{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:25:55Z","timestamp":1786987555755,"version":"build-2736575974"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2018YFC1704600"],"award-info":[{"award-number":["2018YFC1704600"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Complementary Therapies in Clinical Practice"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.ctcp.2021.101484","type":"journal-article","created":{"date-parts":[[2021,9,8]],"date-time":"2021-09-08T13:09:01Z","timestamp":1631106541000},"page":"101484","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Acupuncture for treating chronic stable angina pectoris associated anxiety and depression: A systematic review and meta-analysis"],"prefix":"10.1016","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6048-8111","authenticated-orcid":false,"given":"Mingqi","family":"Tu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongliang","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hantong","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binjun","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofen","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianqiao","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ctcp.2021.101484_bib1","unstructured":"Section of Interventional Cardiology of Chinese Society of Cardiology, Section of Atherosclerosis and Coronary Artery Disease of Chinese Society of Cardiology, Specialty Committee on Prevention and Treatment of Thrombosis of Chinese College of Cardiovascular Physicians, Guideline on the diagnosis and treatment of stable coronary artery disease, Chin. J. Cardiol. 46 (2018) 680\u2013694. https:\/\/doi.org\/10.3760\/cma.j.issn.0253-3758.2018.09.004."},{"key":"10.1016\/j.ctcp.2021.101484_bib2","doi-asserted-by":"crossref","first-page":"2949","DOI":"10.1093\/eurheartj\/eht296","article-title":"2013 ESC guidelines on the management of stable coronary artery disease: the Task Force on the management of stable coronary artery disease of the European Society of Cardiology","volume":"34","author":"Montalescot","year":"2013","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ctcp.2021.101484_bib3","doi-asserted-by":"crossref","first-page":"e56","DOI":"10.1161\/CIR.0000000000000659","article-title":"Heart disease and stroke statistics\u20142019 update: a report from the American Heart Association","volume":"139","author":"Benjamin","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.ctcp.2021.101484_bib4","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1161\/01.CIR.86.5.1485","article-title":"Identification of patients with coronary disease at high risk for loss of employment: a prospective validation study","volume":"86","author":"Mark","year":"1992","journal-title":"Circulation"},{"key":"10.1016\/j.ctcp.2021.101484_bib5","first-page":"1","article-title":"Mood disorders impaired quality of life but not the mortality or morbidity risk in stable coronary heart disease patients","author":"Mayer","year":"2019","journal-title":"Acta Cardiol."},{"key":"10.1016\/j.ctcp.2021.101484_bib6","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1007\/s10654-014-9926-z","article-title":"The association of depression and angina pectoris across 47 countries: findings from the 2002 World Health Survey","volume":"29","author":"Loerbroks","year":"2014","journal-title":"Eur. J. Epidemiol."},{"key":"10.1016\/j.ctcp.2021.101484_bib7","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.jad.2012.04.012","article-title":"Depression, anxiety and cardiovascular disease: which symptoms are associated with increased risk in community dwelling older adults?","volume":"142","author":"Gallagher","year":"2012","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.ctcp.2021.101484_bib8","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1177\/1559827610393868","article-title":"Anxiety, Health risk factors, and chronic disease","volume":"5","author":"Sawchuk","year":"2011","journal-title":"Am. J. Lifestyle Med."},{"key":"10.1016\/j.ctcp.2021.101484_bib9","article-title":"The efficacy of acupuncture for stable angina pectoris: a systematic review and meta-analysis","author":"Yang","year":"2019","journal-title":"Euro. J. Prevent. Cardiol."},{"key":"10.1016\/j.ctcp.2021.101484_bib10","doi-asserted-by":"crossref","first-page":"2991","DOI":"10.3760\/cma.j.issn.0366-6999.20140036","article-title":"Prevalence of depression in coronary heart disease in China: a systematic review and meta-analysis","volume":"127","author":"Ren","year":"2014","journal-title":"Chinese Med J"},{"key":"10.1016\/j.ctcp.2021.101484_bib11","doi-asserted-by":"crossref","first-page":"63","DOI":"10.7861\/clinmedicine.13-1-63","article-title":"Pharmacological treatment of chronic stable angina pectoris","volume":"13","author":"Tarkin","year":"2013","journal-title":"Clin. Med."},{"key":"10.1016\/j.ctcp.2021.101484_bib12","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1097\/JCP.0000000000001153","article-title":"Efficacy and adverse effects of tranylcypromine and tricyclic antidepressants in the treatment of depression: a systematic review and comprehensive meta-analysis","volume":"40","author":"Ulrich","year":"2020","journal-title":"J. Clin. Psychopharmacol."},{"key":"10.1016\/j.ctcp.2021.101484_bib13","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.ctcp.2018.01.008","article-title":"Acupuncture and electroacupuncture for anxiety disorders: a systematic review of the clinical research","volume":"31","author":"Amorim","year":"2018","journal-title":"Compl. Ther. Clin. Pract."},{"key":"10.1016\/j.ctcp.2021.101484_bib14","series-title":"Acupuncture for Depression","author":"Smith","year":"2018"},{"key":"10.1016\/j.ctcp.2021.101484_bib15","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000021583","article-title":"Acupuncture for treating chronic stable angina pectoris-associated anxiety and depression: a protocol for systematic review and meta-analysis","volume":"99","author":"Tu","year":"2020","journal-title":"Medicine"},{"key":"10.1016\/j.ctcp.2021.101484_bib16","first-page":"29","article-title":"A revised tool for assessing risk of bias in randomized trials","volume":"10","author":"Higgins","year":"2016","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.ctcp.2021.101484_bib17","first-page":"417","article-title":"Impacts on neutrophil to lymphocyte ratio in patients of chronic stable angina pectoris treated with acupuncture at Neiguan (PC 6)","volume":"35","author":"Wang","year":"2015","journal-title":"Chin. Acupunct. Moxibustion"},{"key":"10.1016\/j.ctcp.2021.101484_bib18","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1001\/jamainternmed.2019.2407","article-title":"Acupuncture as adjunctive therapy for chronic stable angina: a randomized clinical trial","volume":"179","author":"Zhao","year":"2019","journal-title":"JAMA Int. Med."},{"key":"10.1016\/j.ctcp.2021.101484_bib19","series-title":"Targeted Metabolomic Study of Acupuncture along Meridians for Chronic Stable Angina Prectoris","author":"Chen","year":"2015"},{"key":"10.1016\/j.ctcp.2021.101484_bib20","first-page":"350","article-title":"Effect of acupuncture treatment on quality of life in patients with stable angina pectoris","volume":"18","author":"Liu","year":"2003","journal-title":"Chin. J. Rehabil."},{"key":"10.1016\/j.ctcp.2021.101484_bib21","series-title":"Clinical Analgesic Effect of Acupuncture for Chronic Stable Angina Pectoris Based on Acupoints along Meridians with Location Differrention","author":"Lyu","year":"2015"},{"key":"10.1016\/j.ctcp.2021.101484_bib22","first-page":"16","article-title":"Effect of acupuncture combined with medicine on quality of life in patients with angina pectoris","volume":"22","author":"Xu","year":"2006","journal-title":"J. Clin. Acupunct. Moxibust."},{"key":"10.1016\/j.ctcp.2021.101484_bib23","series-title":"Explore the Acupuncture Effects on the Amplitude of Low Frequency Fluctuation and Fractional Amplitude of Low Frequency Fluctuation in Patients with Chronic Stable Angina at PC6 and HT5","author":"Yin","year":"2018"},{"key":"10.1016\/j.ctcp.2021.101484_bib24","doi-asserted-by":"crossref","first-page":"915","DOI":"10.2471\/BLT.10.076737","article-title":"Acupuncture-related adverse events: a systematic review of the Chinese literature","volume":"88","author":"Zhang","year":"2010","journal-title":"Bull. World Health Organ."},{"key":"10.1016\/j.ctcp.2021.101484_bib25","first-page":"38","article-title":"Meta analysis of the therapeutic effect of acupuncture on stable angina pectoris","volume":"20","author":"Zhou","year":"2018","journal-title":"J. Hubei Univ. Chin. Med."},{"key":"10.1016\/j.ctcp.2021.101484_bib26","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/0006-3223(90)90427-4","article-title":"Adrenergic status in anxiety disorders: platelet alpha2-adrenergic receptor binding, blood pressure, pulse, and plasma catecholamines in panic and generalized anxiety disorders patients and in normal subjects","volume":"28","author":"Cameron","year":"1990","journal-title":"Biol. Psychiatr."},{"key":"10.1016\/j.ctcp.2021.101484_bib27","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.1016\/j.psyneuen.2013.03.020","article-title":"Nrf2 participates in depressive disorders through an anti-inflammatory mechanism","volume":"38","author":"Mart\u00edn-de-Saavedra","year":"2013","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.ctcp.2021.101484_bib28","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1017\/S0033291707002097","article-title":"Depression and anxiety as predictors of heart rate variability after myocardial infarction","volume":"38","author":"Martens","year":"2008","journal-title":"Psychol. Med."},{"key":"10.1016\/j.ctcp.2021.101484_bib29","first-page":"104","article-title":"Depression, anxiety, and stress in patients with coronary heart disease","volume":"89","author":"Belialov","year":"2017","journal-title":"Ter. Arkh."},{"key":"10.1016\/j.ctcp.2021.101484_bib30","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S1003-5257(12)60027-0","article-title":"Clinical study of acupuncture Tongli acupoints on HRV in healthy adults","volume":"28","author":"Wang","year":"2012","journal-title":"J. Clin. Acupunct. Moxibust."},{"key":"10.1016\/j.ctcp.2021.101484_bib31","first-page":"1798","article-title":"Effects of acupuncture at acupoits on heart rate variability in patients with chronic stable angina","volume":"32","author":"Fan","year":"2017","journal-title":"Chin. J. Trad. Chin. Med. Pharm."},{"key":"10.1016\/j.ctcp.2021.101484_bib32","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.niox.2007.07.001","article-title":"Endothelial nitric oxide production is tightly coupled to the citrulline-NO cycle","volume":"17","author":"Flam","year":"2007","journal-title":"Nitric Oxide Biol. Chem."},{"key":"10.1016\/j.ctcp.2021.101484_bib33","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1161\/01.ATV.0000051384.43104.FC","article-title":"Endothelial dysfunction: a marker of atherosclerotic risk","volume":"23","author":"Bonetti","year":"2003","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.ctcp.2021.101484_bib34","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.bbrc.2019.08.032","article-title":"Protein arginine methyltransferase-1 deficiency restrains depression-like behavior of mice by inhibiting inflammation and oxidative stress via Nrf-2","volume":"518","author":"Liu","year":"2019","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ctcp.2021.101484_bib35","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.1242\/jeb.00361","article-title":"The caveolar nitric oxide synthase\/arginine regeneration system for NO production in endothelial cells","volume":"206","author":"Solomonson","year":"2003","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.ctcp.2021.101484_bib36","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.eurpsy.2007.02.006","article-title":"Insular cortex and neuropsychiatric disorders: a review of recent literature","volume":"22","author":"Nagai","year":"2007","journal-title":"Eur. Psychiatr."},{"key":"10.1016\/j.ctcp.2021.101484_bib37","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/j.neubiorev.2011.11.009","article-title":"A meta-analysis of heart rate variability and neuroimaging studies: implications for heart rate variability as a marker of stress and health","volume":"36","author":"Thayer","year":"2012","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.ctcp.2021.101484_bib38","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1007\/s12471-012-0351-1","article-title":"Central nervous system involvement in the autonomic responses to psychological distress","volume":"21","author":"de Morree","year":"2013","journal-title":"Neth. Heart J."},{"key":"10.1016\/j.ctcp.2021.101484_bib39","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.pain.2008.01.011","article-title":"Acupuncture modulates resting state connectivity in default and sensorimotor brain networks","volume":"136","author":"Dhond","year":"2008","journal-title":"Pain"},{"key":"10.1016\/j.ctcp.2021.101484_bib40","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.joim.2017.12.002","article-title":"Brain functional connectivity network studies of acupuncture: a systematic review on resting-state fMRI","volume":"16","author":"Cai","year":"2018","journal-title":"J. Integr. Med."},{"key":"10.1016\/j.ctcp.2021.101484_bib41","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1159\/000089227","article-title":"Influence of anxiety on the course of heart disease after acute myocardial infarction - risk factor or protective function?","volume":"75","author":"Benninghoven","year":"2006","journal-title":"Psychother. Psychosom."},{"key":"10.1016\/j.ctcp.2021.101484_bib42","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1089\/acm.2004.10.777","article-title":"Long-term effects of integrated rehabilitation in patients with advanced angina pectoris: a nonrandomized comparative study","volume":"10","author":"Ballegaard","year":"2004","journal-title":"J. Alternative Compl. Med."}],"container-title":["Complementary Therapies in Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1744388121001833?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1744388121001833?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T18:54:08Z","timestamp":1761677648000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1744388121001833"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":42,"alternative-id":["S1744388121001833"],"URL":"https:\/\/doi.org\/10.1016\/j.ctcp.2021.101484","relation":{},"ISSN":["1744-3881"],"issn-type":[{"value":"1744-3881","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Acupuncture for treating chronic stable angina pectoris associated anxiety and depression: A systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Complementary Therapies in Clinical Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ctcp.2021.101484","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"101484"}}