{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T22:53:56Z","timestamp":1769122436976,"version":"3.49.0"},"reference-count":92,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100020508","name":"Universidad Cat\u00f3lica de Temuco","doi-asserted-by":"publisher","award":["PMAFI-01\/24"],"award-info":[{"award-number":["PMAFI-01\/24"]}],"id":[{"id":"10.13039\/100020508","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Complementary Therapies in Clinical Practice"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1016\/j.ctcp.2025.101960","type":"journal-article","created":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T03:19:20Z","timestamp":1739416760000},"page":"101960","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Moderate intensity continuous training, combined moderate-intensity continuous training vs combined high-intensity interval training in adults with hypertension: Randomized controlled trial"],"prefix":"10.1016","volume":"59","author":[{"given":"Isabel","family":"L\u00f3pez-Ruiz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando Lozano","family":"Ruiz-Poveda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Dolores","family":"Mas\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Ram\u00f3n","family":"Heredia-Elvar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noelia","family":"Gonz\u00e1lez-G\u00e1lvez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"25","key":"10.1016\/j.ctcp.2025.101960_bib1","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1016\/j.jacc.2022.11.005","article-title":"The global burden of cardiovascular diseases and risk: a compass for future health","volume":"80","author":"Vaduganathan","year":"2022","journal-title":"J. Am. Coll. Cardiol."},{"issue":"25","key":"10.1016\/j.ctcp.2025.101960_bib2","doi-asserted-by":"crossref","first-page":"2350","DOI":"10.1016\/j.jacc.2023.11.007","article-title":"Global burden of cardiovascular diseases and risks, 1990-2022","volume":"82","author":"Mensah","year":"2023","journal-title":"J. Am. Coll. Cardiol."},{"issue":"12","key":"10.1016\/j.ctcp.2025.101960_bib3","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1097\/HJH.0000000000003480","volume":"41","author":"Mancia","year":"2023","journal-title":"J. Hypertens."},{"issue":"Suppl 3","key":"10.1016\/j.ctcp.2025.101960_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/sms.12581","article-title":"Exercise as medicine - evidence for prescribing exercise as therapy in 26 different chronic diseases","volume":"25","author":"Pedersen","year":"2015","journal-title":"Scand. J. Med. Sci. Sports"},{"issue":"13","key":"10.1016\/j.ctcp.2025.101960_bib5","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1136\/bjsports-2021-105061","article-title":"Muscle-strengthening activities are associated with lower risk and mortality in major non-communicable diseases: a systematic review and meta-analysis of cohort studies","volume":"56","author":"Momma","year":"2022","journal-title":"Br. J. Sports Med."},{"issue":"1","key":"10.1016\/j.ctcp.2025.101960_bib6","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/eurheartj\/ehaa605","article-title":"2020 ESC Guidelines on sports cardiology and exercise in patients with cardiovascular disease: the Task Force on sports cardiology and exercise in patients with cardiovascular disease of the European Society of Cardiology (ESC)","volume":"42","author":"Pelliccia","year":"2020","journal-title":"Eur. Heart J."},{"issue":"1","key":"10.1016\/j.ctcp.2025.101960_bib7","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1097\/HJH.0000000000003563","article-title":"Lifestyle management of hypertension: international society of hypertension position paper endorsed by the world hypertension league and European society of hypertension","volume":"42","author":"Charchar","year":"2024","journal-title":"J. Hypertens."},{"issue":"17","key":"10.1016\/j.ctcp.2025.101960_bib8","first-page":"e426","volume":"138","author":"Whelton","year":"2018","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.ctcp.2025.101960_bib9","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1093\/eurjpc\/zwaa141","article-title":"Personalized exercise prescription in the prevention and treatment of arterial hypertension: a consensus document from the European association of preventive cardiology (EAPC) and the ESC council on hypertension","volume":"29","author":"Hanssen","year":"2021","journal-title":"Eur. J. Prev. Cardiol."},{"issue":"2","key":"10.1016\/j.ctcp.2025.101960_bib10","doi-asserted-by":"crossref","DOI":"10.1097\/HCR.0000000000000696","article-title":"Working toward optimal exercise prescription: strength training should not Be overlooked","volume":"42","author":"Kaminsky","year":"2022","journal-title":"J Cardiopulm Rehabil Prev"},{"issue":"3","key":"10.1016\/j.ctcp.2025.101960_bib11","doi-asserted-by":"crossref","first-page":"S28","DOI":"10.1016\/j.ihj.2018.03.005","article-title":"Heart rate variability following combined aerobic and resistance training in sedentary hypertensive women: a randomised control trial","volume":"70","author":"Masroor","year":"2018","journal-title":"Indian Heart J."},{"issue":"6","key":"10.1016\/j.ctcp.2025.101960_bib12","doi-asserted-by":"crossref","first-page":"363","DOI":"10.6061\/clinics\/2017(06)06","article-title":"Combined aerobic and resistance training: are there additional benefits for older hypertensive adults?","volume":"72","author":"Lima","year":"2017","journal-title":"Clinics"},{"issue":"2","key":"10.1016\/j.ctcp.2025.101960_bib13","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.ijcard.2014.01.100","article-title":"Heated water-based exercise training reduces 24-hour ambulatory blood pressure levels in resistant hypertensive patients: a randomized controlled trial (HEx trial)","volume":"172","author":"Guimaraes","year":"2014","journal-title":"Int. J. Cardiol."},{"issue":"11","key":"10.1016\/j.ctcp.2025.101960_bib14","doi-asserted-by":"crossref","first-page":"3073","DOI":"10.1519\/JSC.0000000000000537","article-title":"Acute and chronic cardiovascular response to 16 weeks of combined eccentric or traditional resistance and aerobic training in elderly hypertensive women: a randomized controlled trial","volume":"28","author":"Dos Santos","year":"2014","journal-title":"J. Strength Condit Res."},{"issue":"7","key":"10.1016\/j.ctcp.2025.101960_bib15","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1097\/HJH.0000000000003455","article-title":"Exercise characteristics and blood pressure reduction after combined aerobic and resistance training: a systematic review with meta-analysis and meta-regression","volume":"41","author":"Schneider","year":"2023","journal-title":"J. Hypertens."},{"issue":"6","key":"10.1016\/j.ctcp.2025.101960_bib16","doi-asserted-by":"crossref","DOI":"10.3390\/sports11060115","article-title":"Multicomponent training and optimal dosing strategies for adults with hypertension: a systematic review and meta-analysis of randomized controlled trials","volume":"11","author":"L\u00f3pez-Ruiz","year":"2023","journal-title":"Sports"},{"issue":"4","key":"10.1016\/j.ctcp.2025.101960_bib17","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1080\/00913847.2017.1387022","article-title":"The effectiveness of structured exercise in the south Asian population with type 2 diabetes: a systematic review","volume":"45","author":"Albalawi","year":"2017","journal-title":"Physician Sportsmed."},{"issue":"4","key":"10.1016\/j.ctcp.2025.101960_bib18","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.jsams.2018.09.228","article-title":"The effect of high Intensity interval training versus moderate intensity continuous training on arterial stiffness and 24h blood pressure responses: a systematic review and meta-analysis","volume":"22","author":"Way","year":"2019","journal-title":"J. Sci. Med. Sport"},{"issue":"50","key":"10.1016\/j.ctcp.2025.101960_bib19","article-title":"Effects of high-intensity interval training versus moderate-intensity continuous training on blood pressure in patients with hypertension: a meta-analysis","volume":"101","author":"Li","year":"2022","journal-title":"Medicine (Baltim.)"},{"issue":"9","key":"10.1016\/j.ctcp.2025.101960_bib20","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.1007\/s40279-018-0944-y","article-title":"Effects of high-intensity interval training versus moderate-intensity continuous training on blood pressure in adults with pre- to established hypertension: a systematic review and meta-analysis of randomized trials","volume":"48","author":"Costa","year":"2018","journal-title":"Sports Med."},{"issue":"5","key":"10.1016\/j.ctcp.2025.101960_bib21","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1007\/s40279-015-0321-z","article-title":"The impact of high-intensity interval training versus moderate-intensity continuous training on vascular function: a systematic review and meta-analysis","volume":"45","author":"Ramos","year":"2015","journal-title":"Sports Med."},{"key":"10.1016\/j.ctcp.2025.101960_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.exger.2021.111657","article-title":"High-intensity interval training reduces blood pressure in older adults: a systematic review and meta-analysis","volume":"158","author":"Carpes","year":"2022","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.ctcp.2025.101960_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.hipert.2024.07.001","article-title":"Six weeks of a concurrent training therapy improves endothelial function and arterial stiffness in hypertensive adults with minimum non-responders","author":"Alvarez","year":"2024","journal-title":"Hipertens. Riesgo Vasc."},{"issue":"1","key":"10.1016\/j.ctcp.2025.101960_bib24","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1186\/s12944-023-01940-x","article-title":"Effect of resistance training and high-intensity interval training on metabolic parameters and serum level of Sirtuin1 in postmenopausal women with metabolic syndrome: a randomized controlled trial","volume":"22","author":"Kazemi","year":"2023","journal-title":"Lipids Health Dis."},{"key":"10.1016\/j.ctcp.2025.101960_bib25","series-title":"Bases de la programaci\u00f3n del entrenamiento de fuerza: Inde","author":"Badillo","year":"2002"},{"issue":"1","key":"10.1016\/j.ctcp.2025.101960_bib26","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1186\/s40798-022-00513-z","article-title":"Toward a new paradigm in resistance training by means of velocity monitoring: a critical and challenging narrative","volume":"8","author":"Gonz\u00e1lez-Badillo","year":"2022","journal-title":"Sports Med Open"},{"issue":"9","key":"10.1016\/j.ctcp.2025.101960_bib27","doi-asserted-by":"crossref","first-page":"2537","DOI":"10.1519\/JSC.0000000000002881","article-title":"Relationship between velocity loss and repetitions in reserve in the bench press and back squat exercises","volume":"34","author":"Rodr\u00edguez-Rosell","year":"2020","journal-title":"J. Strength Condit Res."},{"issue":"5","key":"10.1016\/j.ctcp.2025.101960_bib28","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1055\/s-0030-1248333","article-title":"Movement velocity as a measure of loading intensity in resistance training","volume":"31","author":"Gonz\u00e1lez-Badillo","year":"2010","journal-title":"Int. J. Sports Med."},{"issue":"9","key":"10.1016\/j.ctcp.2025.101960_bib29","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1249\/MSS.0b013e318213f880","article-title":"Velocity loss as an indicator of neuromuscular fatigue during resistance training","volume":"43","author":"S\u00e1nchez-Medina","year":"2011","journal-title":"Med. Sci. Sports Exerc."},{"key":"10.1016\/j.ctcp.2025.101960_bib30","series-title":"La velocidad de ejecuci\u00f3n como referencia para la programaci\u00f3n, control y evaluaci\u00f3n del entrenamiento de fuerza: Ergotech","author":"Badillo","year":"2017"},{"issue":"8","key":"10.1016\/j.ctcp.2025.101960_bib31","doi-asserted-by":"crossref","DOI":"10.3390\/jcm9082458","article-title":"Movement velocity as A measure of exercise intensity in persons with multiple sclerosis: a validity study","volume":"9","author":"Andreu-Caravaca","year":"2020","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.ctcp.2025.101960_bib32","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.7533","article-title":"Movement velocity can be used to estimate the relative load during the bench press and leg press exercises in older women","volume":"7","author":"Marcos-Pardo","year":"2019","journal-title":"PeerJ"},{"key":"10.1016\/j.ctcp.2025.101960_bib33","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.16175","article-title":"Estimating the one-repetition maximum on the leg-press exercise in female breast cancer survivors","volume":"11","author":"D\u00edez-Fern\u00e1ndez","year":"2023","journal-title":"PeerJ"},{"issue":"1","key":"10.1016\/j.ctcp.2025.101960_bib34","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0210292","article-title":"Comparative effectiveness of aerobic, resistance, and combined training on cardiovascular disease risk factors: a randomized controlled trial","volume":"14","author":"Schroeder","year":"2019","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.ctcp.2025.101960_bib35","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.hipert.2022.09.002","article-title":"Gu\u00eda pr\u00e1ctica sobre el diagn\u00f3stico y tratamiento de la hipertensi\u00f3n arterial en Espa\u00f1a, 2022. Sociedad Espa\u00f1ola de Hipertensi\u00f3n-Liga Espa\u00f1ola para la Lucha contra la Hipertensi\u00f3n Arterial (SEH-LELHA)","volume":"39","author":"Gorostidi","year":"2022","journal-title":"Hipertens. Riesgo Vasc."},{"issue":"7","key":"10.1016\/j.ctcp.2025.101960_bib36","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1001\/archinte.165.7.756","article-title":"Effect of exercise on blood pressure in older persons: a randomized controlled trial","volume":"165","author":"Stewart","year":"2005","journal-title":"Arch. Intern. Med."},{"issue":"1","key":"10.1016\/j.ctcp.2025.101960_bib37","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/s41387-022-00223-1","article-title":"Validation of a multi-frequency bioelectrical impedance analysis device for the assessment of body composition in older adults with type 2 diabetes","volume":"12","author":"Buch","year":"2022","journal-title":"Nutr. Diabetes"},{"issue":"8","key":"10.1016\/j.ctcp.2025.101960_bib38","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1038\/s41430-020-00839-5","article-title":"Comparison of body composition assessment across body mass index categories by two multifrequency bioelectrical impedance analysis devices and dual-energy X-ray absorptiometry in clinical settings","volume":"75","author":"Lahav","year":"2021","journal-title":"Eur. J. Clin. Nutr."},{"key":"10.1016\/j.ctcp.2025.101960_bib39","series-title":"Sociedad Internacional para el Avance de la Cineantropometr\u00eda (ISAK)","author":"Marfell Jones","year":"2006"},{"key":"10.1016\/j.ctcp.2025.101960_bib40","first-page":"22","article-title":"Automated devices for clinical use","volume":"16\u201324","author":"Hypertension","year":"2010","journal-title":"Dabl Educational Trust, resting cuff sizes"},{"issue":"7","key":"10.1016\/j.ctcp.2025.101960_bib41","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1097\/HJH.0000000000002843","article-title":"2021 European Society of Hypertension practice guidelines for office and out-of-office blood pressure measurement","volume":"39","author":"Stergiou","year":"2021","journal-title":"J. Hypertens."},{"issue":"2","key":"10.1016\/j.ctcp.2025.101960_bib42","first-page":"69","article-title":"Grip and pinch strength: normative data for adults","volume":"66","author":"Mathiowetz","year":"1985","journal-title":"Arch. Phys. Med. Rehabil."},{"issue":"3","key":"10.1016\/j.ctcp.2025.101960_bib43","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1055\/s-0042-120324","article-title":"Velocity loss as a variable for monitoring resistance exercise","volume":"38","author":"Gonz\u00e1lez-Badillo","year":"2017","journal-title":"Int. J. Sports Med."},{"issue":"2","key":"10.1016\/j.ctcp.2025.101960_bib44","doi-asserted-by":"crossref","first-page":"E80","DOI":"10.1055\/s-0043-102933","article-title":"Estimation of relative load from bar velocity in the full back squat exercise","volume":"1","author":"S\u00e1nchez-Medina","year":"2017","journal-title":"Sports Medicine Int. Open"},{"issue":"1","key":"10.1016\/j.ctcp.2025.101960_bib45","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1097\/00005768-200101000-00020","article-title":"Knee biomechanics of the dynamic squat exercise","volume":"33","author":"Escamilla","year":"2001","journal-title":"Med. Sci. Sports Exerc."},{"issue":"12","key":"10.1016\/j.ctcp.2025.101960_bib46","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1080\/02640414.2015.1090010","article-title":"Movement velocity as a measure of exercise intensity in three lower limb exercises","volume":"34","author":"Concei\u00e7\u00e3o","year":"2016","journal-title":"J. Sports Sci."},{"issue":"8","key":"10.1016\/j.ctcp.2025.101960_bib47","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1139\/apnm-2019-0829","article-title":"Velocity-based resistance training: impact of velocity loss in the set on neuromuscular performance and hormonal response","volume":"45","author":"Rodr\u00edguez-Rosell","year":"2020","journal-title":"Appl. Physiol. Nutr. Metabol."},{"issue":"6","key":"10.1016\/j.ctcp.2025.101960_bib48","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1519\/JSC.0000000000002017","article-title":"Movement velocity as a measure of level of effort during resistance exercise","volume":"33","author":"Mor\u00e1n-Navarro","year":"2019","journal-title":"J. Strength Condit Res."},{"key":"10.1016\/j.ctcp.2025.101960_bib49","article-title":"La importancia de los ajustes de la bicicleta en la prevenci\u00f3n de las lesiones en el ciclismo: aplicaciones pr\u00e1cticas","author":"G\u00f3mez-Puerto","year":"2008","journal-title":"Rev. Andal. Med. Deporte"},{"issue":"1","key":"10.1016\/j.ctcp.2025.101960_bib50","first-page":"5","article-title":"Pruebas de esfuerzo en medicina del deporte","volume":"33","author":"Marqueta","year":"2016","journal-title":"Documento de consenso de la Sociedad Espa\u00f1ola de Medicina del Deporte (SEMED-FEMEDE). Archivos de medicina del deporte: revista de la Federaci\u00f3n Espa\u00f1ola de Medicina del Deporte y de la Confederaci\u00f3n Iberoamericana de Medicina del Deporte"},{"key":"10.1016\/j.ctcp.2025.101960_bib51","first-page":"328","article-title":"ACSM's guidelines for exercise testing and prescription 9th","volume":"58","author":"Ferguson","year":"2014","journal-title":"J. Can. Chiropr. Assoc."},{"key":"10.1016\/j.ctcp.2025.101960_bib52","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2022.845225","article-title":"Effects of high-intensity interval vs. Moderate-intensity continuous training on cardiac rehabilitation in patients with cardiovascular disease: a systematic review and meta-analysis","volume":"9","author":"Yue","year":"2022","journal-title":"Front. Cardiovasc. Med."},{"key":"10.1016\/j.ctcp.2025.101960_bib53","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/192479","article-title":"Effects of high intensity interval versus moderate continuous training on markers of ventilatory and cardiac efficiency in coronary heart disease patients","volume":"2015","author":"Cardozo","year":"2015","journal-title":"Sci. World J."},{"issue":"9","key":"10.1016\/j.ctcp.2025.101960_bib54","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1016\/j.amjcard.2004.12.063","article-title":"Effectiveness of high-intensity interval training for the rehabilitation of patients with coronary artery disease","volume":"95","author":"Warburton","year":"2005","journal-title":"Am. J. Cardiol."},{"issue":"1","key":"10.1016\/j.ctcp.2025.101960_bib55","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1093\/eurjpc\/zwab007","article-title":"Exercise intensity assessment and prescription in cardiovascular rehabilitation and beyond: why and how: a position statement from the Secondary Prevention and Rehabilitation Section of the European Association of Preventive Cardiology","volume":"29","author":"Hansen","year":"2021","journal-title":"European J.Prev. Cardiol."},{"key":"10.1016\/j.ctcp.2025.101960_bib56","series-title":"Borg's Perceived Exertion and Pain Scales","author":"Borg","year":"1998"},{"key":"10.1016\/j.ctcp.2025.101960_bib57","series-title":"Training and Racing with a Power Meter","author":"Allen","year":"2019"},{"issue":"1","key":"10.1016\/j.ctcp.2025.101960_bib58","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1249\/MSS.0b013e31818cb278","article-title":"Progressive statistics for studies in sports medicine and exercise science","volume":"41","author":"Hopkins","year":"2009","journal-title":"Med. Sci. Sports Exerc."},{"issue":"14","key":"10.1016\/j.ctcp.2025.101960_bib87","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1096\/fj.02-0367com","article-title":"Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1","volume":"16","author":"Baar","year":"2002","journal-title":"FASEB J."},{"issue":"3 Pt 1","key":"10.1016\/j.ctcp.2025.101960_bib59","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1161\/01.HYP.30.3.405","article-title":"Reduced plasma concentrations of nitrogen oxide in individuals with essential hypertension","volume":"30","author":"Node","year":"1997","journal-title":"Hypertension"},{"issue":"8670","key":"10.1016\/j.ctcp.2025.101960_bib60","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/S0140-6736(89)91013-1","article-title":"Effects of endothelium-derived nitric oxide on peripheral arteriolar tone in man","volume":"2","author":"Vallance","year":"1989","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.ctcp.2025.101960_bib61","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1161\/01.HYP.0000252425.06216.26","article-title":"Contribution of endothelial nitric oxide to blood pressure in humans","volume":"49","author":"Gamboa","year":"2007","journal-title":"Hypertension"},{"issue":"5","key":"10.1016\/j.ctcp.2025.101960_bib62","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1161\/HYPERTENSIONAHA.114.03575","article-title":"Endothelial dysfunction and hypertension","volume":"64","author":"Brandes","year":"2014","journal-title":"Hypertension"},{"issue":"6","key":"10.1016\/j.ctcp.2025.101960_bib63","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1038\/hr.2011.39","article-title":"Oxidative stress and endothelial dysfunction in hypertension","volume":"34","author":"Schulz","year":"2011","journal-title":"Hypertens. Res."},{"key":"10.1016\/j.ctcp.2025.101960_bib64","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.atherosclerosis.2021.07.009","article-title":"Effects of resistance training on endothelial function: a systematic review and meta-analysis","volume":"333","author":"Silva","year":"2021","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.ctcp.2025.101960_bib65","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/3756750","article-title":"Exercise for prevention and relief of cardiovascular disease: prognoses, mechanisms, and approaches","volume":"2019","author":"Tian","year":"2019","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"12","key":"10.1016\/j.ctcp.2025.101960_bib66","doi-asserted-by":"crossref","first-page":"2501","DOI":"10.1097\/HJH.0000000000002581","article-title":"Effect of aerobic and resistance exercise training on inflammation, endothelial function and ambulatory blood pressure in middle-aged hypertensive patients","volume":"38","author":"Boeno","year":"2020","journal-title":"J. Hypertens."},{"issue":"8","key":"10.1016\/j.ctcp.2025.101960_bib67","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/nrendo.2012.49","article-title":"Muscles, exercise and obesity: skeletal muscle as a secretory organ","volume":"8","author":"Pedersen","year":"2012","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.ctcp.2025.101960_bib68","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2023.1043108","article-title":"Effect of continuous aerobic exercise on endothelial function: a systematic review and meta-analysis of randomized controlled trials","volume":"14","author":"Tao","year":"2023","journal-title":"Front. Physiol."},{"key":"10.1016\/j.ctcp.2025.101960_bib69","article-title":"Effects of different intensities and durations of aerobic exercise on vascular endothelial function in middle-aged and elderly people: a meta-analysis","volume":"12","author":"You","year":"2021","journal-title":"Front. Physiol."},{"issue":"30","key":"10.1016\/j.ctcp.2025.101960_bib70","doi-asserted-by":"crossref","first-page":"4686","DOI":"10.2174\/1381612822666160510125011","article-title":"Preventive and therapeutic role of muscle contraction against chronic diseases","volume":"22","author":"Di Raimondo","year":"2016","journal-title":"Curr. Pharm. Des."},{"issue":"4","key":"10.1016\/j.ctcp.2025.101960_bib71","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1210\/endrev\/bnaa016","article-title":"Muscle-organ crosstalk: the emerging roles of myokines","volume":"41","author":"Severinsen","year":"2020","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.ctcp.2025.101960_bib72","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1042\/bse0420105","article-title":"The anti-inflammatory effect of exercise: its role in diabetes and cardiovascular disease control","volume":"42","author":"Pedersen","year":"2006","journal-title":"Essays Biochem."},{"issue":"5","key":"10.1016\/j.ctcp.2025.101960_bib73","doi-asserted-by":"crossref","DOI":"10.3390\/nu13051459","article-title":"The role of exercise, diet, and cytokines in preventing obesity and improving adipose tissue","volume":"13","author":"Atakan","year":"2021","journal-title":"Nutrients"},{"issue":"9","key":"10.1016\/j.ctcp.2025.101960_bib74","doi-asserted-by":"crossref","DOI":"10.1111\/obr.13275","article-title":"Effect of resistance training with and without caloric restriction on visceral fat: a systemic review and meta-analysis","volume":"22","author":"Khalafi","year":"2021","journal-title":"Obes. Rev."},{"key":"10.1016\/j.ctcp.2025.101960_bib75","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/s40279-021-01562-2","article-title":"The effect of resistance training in healthy adults on body fat percentage, fat mass and visceral fat: a systematic review and meta-analysis","volume":"52","author":"Wewege","year":"2022","journal-title":"Sports Med."},{"issue":"5","key":"10.1016\/j.ctcp.2025.101960_bib76","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1097\/HCR.0000000000000525","article-title":"Muscular strength and cardiovascular disease: an updated state-of-the-art narrative review","volume":"40","author":"Carbone","year":"2020","journal-title":"J Cardiopulm Rehabil Prev"},{"issue":"6","key":"10.1016\/j.ctcp.2025.101960_bib77","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1111\/obr.12532","article-title":"The effects of high-intensity interval training vs. moderate-intensity continuous training on body composition in overweight and obese adults: a systematic review and meta-analysis","volume":"18","author":"Wewege","year":"2017","journal-title":"Obes. Rev."},{"issue":"8","key":"10.1016\/j.ctcp.2025.101960_bib78","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1111\/obr.12536","article-title":"A systematic review and meta-analysis of interval training versus moderate-intensity continuous training on body adiposity","volume":"18","author":"Keating","year":"2017","journal-title":"Obes. Rev."},{"issue":"1","key":"10.1016\/j.ctcp.2025.101960_bib79","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/obr.12766","article-title":"The influence of high-intensity interval training on anthropometric variables of adults with overweight or obesity: a systematic review and network meta-analysis","volume":"20","author":"Andreato","year":"2019","journal-title":"Obes. Rev."},{"issue":"4","key":"10.1016\/j.ctcp.2025.101960_bib80","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1152\/physrev.90100.2007","article-title":"Muscle as an endocrine organ: focus on muscle-derived interleukin-6","volume":"88","author":"Pedersen","year":"2008","journal-title":"Physiol. Rev."},{"issue":"5","key":"10.1016\/j.ctcp.2025.101960_bib81","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S0021-9290(96)00170-4","article-title":"Neural adaptations with chronic physical activity","volume":"30","author":"Enoka","year":"1997","journal-title":"J. Biomech."},{"issue":"5 Suppl","key":"10.1016\/j.ctcp.2025.101960_bib82","doi-asserted-by":"crossref","first-page":"S135","DOI":"10.1249\/00005768-198810001-00009","article-title":"Neural adaptation to resistance training","volume":"20","author":"Sale","year":"1988","journal-title":"Med. Sci. Sports Exerc."},{"issue":"7","key":"10.1016\/j.ctcp.2025.101960_bib83","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1113\/JP277250","article-title":"The increase in muscle force after 4 weeks of strength training is mediated by adaptations in motor unit recruitment and rate coding","volume":"597","author":"Del Vecchio","year":"2019","journal-title":"J. Physiol."},{"key":"10.1016\/j.ctcp.2025.101960_bib84","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/bs.pmbts.2015.07.016","article-title":"Endurance exercise and the regulation of skeletal muscle metabolism","volume":"135","author":"Booth","year":"2015","journal-title":"Prog Mol Biol Transl Sci"},{"issue":"4","key":"10.1016\/j.ctcp.2025.101960_bib85","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.imr.2014.09.004","article-title":"Exercise-induced PGC-1\u03b1 transcriptional factors in skeletal muscle","volume":"3","author":"Jung","year":"2014","journal-title":"Integr. Med.Res."},{"issue":"20","key":"10.1016\/j.ctcp.2025.101960_bib86","doi-asserted-by":"crossref","first-page":"19587","DOI":"10.1074\/jbc.M408862200","article-title":"Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway","volume":"280","author":"Akimoto","year":"2005","journal-title":"J. Biol. Chem."},{"issue":"9","key":"10.1016\/j.ctcp.2025.101960_bib88","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1139\/apnm-2020-0005","article-title":"PGC-1\u03b1-mediated regulation of mitochondrial function and physiological implications","volume":"45","author":"Halling","year":"2020","journal-title":"Appl. Physiol. Nutr. Metabol."},{"issue":"4","key":"10.1016\/j.ctcp.2025.101960_bib89","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1055\/a-1506-3007","article-title":"Effects of concurrent training on 1RM and VO2 in adults: systematic review with meta-analysis","volume":"43","author":"Pito","year":"2022","journal-title":"Int. J. Sports Med."},{"key":"10.1016\/j.ctcp.2025.101960_bib90","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2022.113888","article-title":"Impact of concurrent training versus aerobic or resistance training on cardiorespiratory fitness and muscular strength in middle-aged to older adults: a systematic review and meta-analysis","volume":"254","author":"Khalafi","year":"2022","journal-title":"Physiol. Behav."},{"issue":"9","key":"10.1016\/j.ctcp.2025.101960_bib91","doi-asserted-by":"crossref","first-page":"2883","DOI":"10.1113\/JP272270","article-title":"Concurrent exercise training: do opposites distract?","volume":"595","author":"Coffey","year":"2017","journal-title":"J. Physiol."},{"issue":"7","key":"10.1016\/j.ctcp.2025.101960_bib92","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1111\/sms.12678","article-title":"Effects of velocity loss during resistance training on athletic performance, strength gains and muscle adaptations","volume":"27","author":"Pareja-Blanco","year":"2017","journal-title":"Scand. J. Med. Sci. Sports"}],"container-title":["Complementary Therapies in Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1744388125000258?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1744388125000258?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T23:04:15Z","timestamp":1762556655000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1744388125000258"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":92,"alternative-id":["S1744388125000258"],"URL":"https:\/\/doi.org\/10.1016\/j.ctcp.2025.101960","relation":{},"ISSN":["1744-3881"],"issn-type":[{"value":"1744-3881","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Moderate intensity continuous training, combined moderate-intensity continuous training vs combined high-intensity interval training in adults with hypertension: Randomized controlled trial","name":"articletitle","label":"Article Title"},{"value":"Complementary Therapies in Clinical Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ctcp.2025.101960","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"101960"}}