{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T21:59:01Z","timestamp":1790114341652,"version":"4.0.1"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Research Committee of the Pharmacy School of Shahid Beheshti University of Medical Sciences"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Complementary Therapies in Medicine"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.ctim.2016.08.001","type":"journal-article","created":{"date-parts":[[2016,9,9]],"date-time":"2016-09-09T18:49:11Z","timestamp":1473446951000},"page":"29-34","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"special_numbering":"C","title":["Evaluating the effect of Matricaria recutita and Mentha piperita herbal mouthwash on management of oral mucositis in patients undergoing hematopoietic stem cell transplantation: A randomized, double blind, placebo controlled clinical trial"],"prefix":"10.1016","volume":"29","author":[{"given":"Maria","family":"Tavakoli Ardakani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Ghassemi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahshid","family":"Mehdizadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faraz","family":"Mojab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamshid","family":"Salamzadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samaneh","family":"Ghassemi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbas","family":"Hajifathali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.ctim.2016.08.001_bib0005","doi-asserted-by":"crossref","first-page":"e74","DOI":"10.4317\/jced.51313","article-title":"Prevention and treatment of oral mucositis in patients receiving chemotherapy","volume":"6","author":"Alvari\u00f1o-Mart\u00edn","year":"2014","journal-title":"J Clin Exp Dent"},{"issue":"12","key":"10.1016\/j.ctim.2016.08.001_bib0010","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1002\/hed.10318","article-title":"Oral mucositis: a challenging complication of radiotherapy, chemotherapy, and radiochemotherapy: part 1, pathogenesis and prophylaxis of mucositis","volume":"25","author":"Scully","year":"2003","journal-title":"Head Neck"},{"issue":"6 Suppl. 3","key":"10.1016\/j.ctim.2016.08.001_bib0015","first-page":"3","article-title":"Oral mucositis in cancer therapy","volume":"2","author":"Sonis","year":"2004","journal-title":"J Support Oncol"},{"issue":"9 Suppl. 4","key":"10.1016\/j.ctim.2016.08.001_bib0020","first-page":"13","article-title":"Clinical and economic consequences of mucositis induced by chemotherapy and\/or radiation therapy","volume":"5","author":"Murphy","year":"2007","journal-title":"J Support Oncol"},{"issue":"4","key":"10.1016\/j.ctim.2016.08.001_bib0025","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1038\/nrc1318","article-title":"The pathobiology of mucositis","volume":"4","author":"Sonis","year":"2004","journal-title":"Nat Rev Cancer"},{"issue":"1","key":"10.1016\/j.ctim.2016.08.001_bib0030","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.cden.2007.10.002","article-title":"Peterson management of oral mucositis In patients with cancer","volume":"52","author":"Lalla","year":"2008","journal-title":"Dent Clin North Am"},{"issue":"1","key":"10.1016\/j.ctim.2016.08.001_bib0035","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/hed.10326","article-title":"Oral mucositis: a challenging complication of radiotherapy, chemotherapy, and radiochemotherapy. Part 2: diagnosis and management of mucositis","volume":"26","author":"Scully","year":"2004","journal-title":"Head Neck"},{"key":"10.1016\/j.ctim.2016.08.001_bib0040","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1002\/cncr.28592","article-title":"MASCC\/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy","volume":"120","author":"Lalla","year":"2014","journal-title":"Cancer"},{"issue":"3","key":"10.1016\/j.ctim.2016.08.001_bib0045","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1080\/09553000500103033","article-title":"Effects of dexpanthenol with or without Aloe Vera extract on radiation-induced oral mucositis: preclinical studies","volume":"81","author":"D\u00f6rr","year":"2005","journal-title":"Int J Rad Biol"},{"issue":"4","key":"10.1016\/j.ctim.2016.08.001_bib0050","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.ctcp.2005.02.001","article-title":"Novel approaches to radiotherapy induced skin reactions: a literature review","volume":"11","author":"Maddocks-Jennings","year":"2005","journal-title":"Complement Ther Clin Pract"},{"key":"10.1016\/j.ctim.2016.08.001_bib0055","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.ijrobp.2004.02.012","article-title":"Phase II double-blind randomized study comparing oral Aloe Vera versus placebo to prevent radiation-related mucositis in patients with head-and-neck neoplasm\u2019s","volume":"60","author":"Su","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"2","key":"10.1016\/j.ctim.2016.08.001_bib0060","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.ejon.2009.01.002","article-title":"Evaluating the effects of the essential oils Leptospermum scoparium (manuka) and Kunzea ericoides (kanuka) on radiotherapy induced mucositis: a randomized, placebo controlled feasibility study","volume":"13","author":"Maddocks-Jennings","year":"2009","journal-title":"Eur J Oncol Nurs"},{"issue":"9","key":"10.1016\/j.ctim.2016.08.001_bib0065","doi-asserted-by":"crossref","first-page":"82","DOI":"10.4103\/0973-7847.79103","article-title":"Chamomile (Matricaria chamomilla L.): an overview","volume":"5","author":"Singh","year":"2011","journal-title":"Pharmacogn Rev"},{"key":"10.1016\/j.ctim.2016.08.001_bib0070","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.chroma.2015.01.067","article-title":"Rapid evaluation and comparison of natural products and antioxidant activity in calendula, feverfew, and German chamomile extracts","volume":"1385","author":"Agatonovic-Kustrin","year":"2015","journal-title":"J Chromatogr A"},{"issue":"6","key":"10.1016\/j.ctim.2016.08.001_bib0075","first-page":"895","article-title":"Chamomile: a herbal an herbal medicine of the past with bright future","volume":"3","author":"Srivastava","year":"2010","journal-title":"Mol Med Rep"},{"issue":"16","key":"10.1016\/j.ctim.2016.08.001_bib0080","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1016\/j.phytochem.2004.07.011","article-title":"Isolation, identification and stability of acylated derivatives of apigenin 7-o-glucoside from chamomile (Chamomilla recutita [L.] Rauschert)","volume":"65","author":"Svehlikova","year":"2004","journal-title":"Phytochemistry"},{"issue":"7","key":"10.1016\/j.ctim.2016.08.001_bib0085","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1002\/ptr.1900","article-title":"A review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.)","volume":"20","author":"McKay","year":"2006","journal-title":"Phytother Res"},{"issue":"1","key":"10.1016\/j.ctim.2016.08.001_bib0090","doi-asserted-by":"crossref","first-page":"12","DOI":"10.25004\/IJPSDR.2010.020102","article-title":"Pharmacological potential of matricaria recutita\u2014a review","volume":"2","author":"Gupta","year":"2010","journal-title":"Int J Pharm Sci Drug Res"},{"issue":"1\u20132","key":"10.1016\/j.ctim.2016.08.001_bib0095","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.phymed.2003.11.003","article-title":"Wild chamomile (Matricaria recutita L.) mouthwashes in methotrexate-induced oral mucositis","volume":"12","author":"Mazokopakis","year":"2005","journal-title":"Phytomedicine"},{"issue":"1","key":"10.1016\/j.ctim.2016.08.001_bib0100","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.jep.2011.05.029","article-title":"Anti-allergic activity of German chamomile (Matricaria recutita L.) in mast cell mediated allergy model","volume":"137","author":"Chandrashekhar","year":"2011","journal-title":"J Ethnopharmacol"},{"issue":"5","key":"10.1016\/j.ctim.2016.08.001_bib0105","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1055\/s-2003-39704","article-title":"Antimicrobial and antioxidant activities of three mentha species essential oils","volume":"69","author":"Mimica-Dukic","year":"2003","journal-title":"Planta Med"},{"issue":"14","key":"10.1016\/j.ctim.2016.08.001_bib0110","doi-asserted-by":"crossref","first-page":"3943","DOI":"10.1021\/jf011476k","article-title":"Antimicrobial screening of mentha piperita essential oils","volume":"50","author":"I\u015fcan","year":"2002","journal-title":"J Agric Food Chem"},{"issue":"8","key":"10.1016\/j.ctim.2016.08.001_bib0115","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1002\/ptr.1936","article-title":"A review of the bioactivity and potential health benefits of peppermint tea (Mentha piperita L.)","volume":"20","author":"McKay","year":"2006","journal-title":"Phytother Res"},{"issue":"6","key":"10.1016\/j.ctim.2016.08.001_bib0120","doi-asserted-by":"crossref","first-page":"327","DOI":"10.2310\/6620.2011.10080","article-title":"Mentha piperita (peppermint)","volume":"21","author":"Herro","year":"2010","journal-title":"Dermatitis"},{"issue":"Suppl. 1","key":"10.1016\/j.ctim.2016.08.001_bib0125","first-page":"31","article-title":"Inhibition by the essential oils of peppermint and spearmint of the growth of pathogenic bacteria","volume":"106","author":"Imai","year":"2001","journal-title":"Microbios"},{"issue":"5","key":"10.1016\/j.ctim.2016.08.001_bib0130","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1055\/s-2003-39704","article-title":"Antimicrobial and antioxidant activities of three Mentha species essential oils","volume":"69","author":"Mimica-Duki\u0107","year":"2003","journal-title":"Planta Med"},{"issue":"10","key":"10.1016\/j.ctim.2016.08.001_bib0135","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.3109\/13880209.2014.989623","article-title":"Synergistic anti-candidal activity and mode of action of Mentha piperita essential oil and its major components","volume":"53","author":"Samber","year":"2015","journal-title":"Pharm Biol"},{"issue":"1\u20134","key":"10.1016\/j.ctim.2016.08.001_bib0140","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1002\/biof.5520220117","article-title":"Anticancer and radioprotective potentials of Mentha piperita","volume":"22","author":"Kumar","year":"2004","journal-title":"Biofactors"},{"issue":"6\u20137","key":"10.1016\/j.ctim.2016.08.001_bib0145","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1078\/094471103322331467","article-title":"Virucidal effect of peppermint oil on the enveloped viruses herpes simplex virus type 1 and type 2 in vitro","volume":"10","author":"Schuhmacher","year":"2003","journal-title":"Phytomedicine"},{"issue":"1","key":"10.1016\/j.ctim.2016.08.001_bib0150","doi-asserted-by":"crossref","first-page":"124","DOI":"10.2174\/138955713804484686","article-title":"Menthol-pharmacology of an important naturally medicinal cool","volume":"13","author":"Farco","year":"2013","journal-title":"Mini Rev Med Chem"},{"issue":"5","key":"10.1016\/j.ctim.2016.08.001_bib0155","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/j.jaad.2007.04.008","article-title":"Menthol: a refreshing look at this ancient compound","volume":"57","author":"Patel","year":"2007","journal-title":"J Am Acad Dermatol"},{"issue":"9 Suppl","key":"10.1016\/j.ctim.2016.08.001_bib0160","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1002\/cncr.20162","article-title":"Perspectives on cancer therapy-induced mucosal injury: pathogenesis, measurement epidemiology and consequences for patients","volume":"100","author":"Sonis","year":"2004","journal-title":"Cancer"},{"issue":"Suppl. 1","key":"10.1016\/j.ctim.2016.08.001_bib0165","doi-asserted-by":"crossref","first-page":"S10","DOI":"10.1016\/S1462-3889(07)70003-0","article-title":"Ensuring accurate oral mucositis assessment in the european group for blood and marrow transplantation prospective oral mucositis audit","volume":"11","author":"Quinn","year":"2007","journal-title":"Eur J Oncol Nurs"},{"issue":"2","key":"10.1016\/j.ctim.2016.08.001_bib0170","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1046\/j.1365-2141.2000.02202.x","article-title":"Prospective evaluation of oral mucositis in patients receiving myeloablative conditioning regimens and haemopoietic progenitor rescue","volume":"110","author":"Wardley","year":"2000","journal-title":"Br J Haematol"},{"issue":"3","key":"10.1016\/j.ctim.2016.08.001_bib0175","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/0022-3913(91)90264-W","article-title":"Management of oral mucositis during local radiation and systemic chemotherapy: a study of 98 patients","volume":"66","author":"Carl","year":"1991","journal-title":"J Prosthet Dent"},{"issue":"3","key":"10.1016\/j.ctim.2016.08.001_bib0180","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1002\/(SICI)1097-0142(19960201)77:3<522::AID-CNCR14>3.0.CO;2-6","article-title":"Prospective evaluation of a chamomile mouthwash for prevention of 5-FU-induced oral mucositis","volume":"77","author":"Fidler","year":"1996","journal-title":"Cancer"},{"issue":"4","key":"10.1016\/j.ctim.2016.08.001_bib0185","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1097\/NCC.0000000000000194","article-title":"Use of chamomilla recutita in the prevention and treatment of oral mucositis in patients undergoing hematopoietic stem cell transplantation: a randomized, controlled, phase II clinical trial","volume":"38","author":"Braga","year":"2015","journal-title":"Cancer Nurs"}],"container-title":["Complementary Therapies in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0965229916301066?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0965229916301066?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T17:05:32Z","timestamp":1760807132000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0965229916301066"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":37,"alternative-id":["S0965229916301066"],"URL":"https:\/\/doi.org\/10.1016\/j.ctim.2016.08.001","relation":{},"ISSN":["0965-2299"],"issn-type":[{"value":"0965-2299","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluating the effect of Matricaria recutita and Mentha piperita herbal mouthwash on management of oral mucositis in patients undergoing hematopoietic stem cell transplantation: A randomized, double blind, placebo controlled clinical trial","name":"articletitle","label":"Article Title"},{"value":"Complementary Therapies in Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ctim.2016.08.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}