{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:52:00Z","timestamp":1785419520713,"version":"3.56.0"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:00:00Z","timestamp":1759190400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Complementary Therapies in Medicine"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.ctim.2025.103254","type":"journal-article","created":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T00:53:25Z","timestamp":1759798405000},"page":"103254","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Effectiveness of massage therapy for constipation in children with cerebral palsy: A systematic review and meta-analysis"],"prefix":"10.1016","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-3407-1272","authenticated-orcid":false,"given":"Mengqi","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0359-761X","authenticated-orcid":false,"given":"Guorui","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1614-0931","authenticated-orcid":false,"given":"Ruobing","family":"Lan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2386-7544","authenticated-orcid":false,"given":"Yu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6580-1894","authenticated-orcid":false,"given":"Shuying","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5413-2155","authenticated-orcid":false,"given":"Xiaolei","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2281-4729","authenticated-orcid":false,"given":"Yuxing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6397-8780","authenticated-orcid":false,"given":"Duo","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.ctim.2025.103254_bib1","first-page":"8","article-title":"A report: the definition and classification of cerebral palsy April 2006","volume":"49","author":"Rosenbaum","year":"2007","journal-title":"Dev Med Child Neurol"},{"issue":"12","key":"10.1016\/j.ctim.2025.103254_bib2","doi-asserted-by":"crossref","DOI":"10.1111\/dmcn.15346","article-title":"Global prevalence of cerebral palsy: a systematic analysis","volume":"64","author":"McIntyre","year":"2022","journal-title":"Dev Med Child Neurol"},{"issue":"9924","key":"10.1016\/j.ctim.2025.103254_bib3","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1016\/S0140-6736(13)61835-8","article-title":"Cerebral palsy","volume":"383","author":"Colver","year":"2014","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.ctim.2025.103254_bib4","article-title":"Cerebral palsy","volume":"2","author":"Graham","year":"2016","journal-title":"Nat Rev Dis Prim"},{"key":"10.1016\/j.ctim.2025.103254_bib5","series-title":"Data and Statistics for Cerebral palsy","author":"CDC","year":"2018"},{"issue":"9","key":"10.1016\/j.ctim.2025.103254_bib6","doi-asserted-by":"crossref","first-page":"e216","DOI":"10.1111\/j.1469-8749.2010.03701.x","article-title":"Prevalence and clinical presentation of constipation in children with severe generalized cerebral palsy","volume":"52","author":"Veugelers","year":"2010","journal-title":"Dev Med Child Neurol"},{"issue":"5","key":"10.1016\/j.ctim.2025.103254_bib7","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0387-7604(99)00025-X","article-title":"Gastrointestinal manifestations in children with cerebral palsy","volume":"21","author":"Del Giudice","year":"1999","journal-title":"Brain Dev"},{"issue":"3","key":"10.1016\/j.ctim.2025.103254_bib8","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0003-9993(03)00479-9","article-title":"Colonic transit time and constipation in children with spastic cerebral palsy","volume":"85","author":"Park","year":"2004","journal-title":"Arch Phys Med Rehabil"},{"issue":"2","key":"10.1016\/j.ctim.2025.103254_bib9","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/BF01308169","article-title":"Association of constipation with neurologic diseases","volume":"37","author":"Johanson","year":"1992","journal-title":"Dig Dis Sci"},{"issue":"1","key":"10.1016\/j.ctim.2025.103254_bib10","article-title":"Factors associated with the stool characteristics of children with cerebral palsy and chronic constipation","volume":"112","author":"Garc\u00eda","year":"2019","journal-title":"Rev Esp Enferm Dig"},{"issue":"5","key":"10.1016\/j.ctim.2025.103254_bib11","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1111\/ipd.12488","article-title":"Constipation, antiepileptic drugs, and gingivitis in children and adolescents with cerebral palsy","volume":"29","author":"Ferreira","year":"2019","journal-title":"Int J Paediatr Dent"},{"issue":"4","key":"10.1016\/j.ctim.2025.103254_bib12","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.seizure.2010.12.011","article-title":"Gastrointestinal adverse effects of antiepileptic drugs in intractable epileptic patients","volume":"20","author":"Jahromi","year":"2011","journal-title":"Seizure"},{"issue":"2","key":"10.1016\/j.ctim.2025.103254_bib13","doi-asserted-by":"crossref","first-page":"122","DOI":"10.5223\/pghn.2019.22.2.122","article-title":"Evaluation and treatment of malnutrition and associated gastrointestinal complications in children with cerebral palsy","volume":"22","author":"Trivi\u0107","year":"2019","journal-title":"Pedia Gastroenterol Hepatol Nutr"},{"issue":"2","key":"10.1016\/j.ctim.2025.103254_bib14","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1002\/ddrr.18","article-title":"Gastrointestinal disorders in children with neurodevelopmental disabilities","volume":"14","author":"Sullivan","year":"2008","journal-title":"Dev Disabil Res Rev"},{"issue":"12","key":"10.1016\/j.ctim.2025.103254_bib15","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1111\/jpc.12675","article-title":"Factors relating to hospitalisation and economic burden of paediatric constipation in the state of Victoria, Australia, 2002-2009","volume":"50","author":"Ansari","year":"2014","journal-title":"J Paediatr Child Health"},{"issue":"5","key":"10.1016\/j.ctim.2025.103254_bib16","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1097\/MOP.0b013e32832ff241","article-title":"Recent advances in chronic constipation","volume":"21","author":"Walia","year":"2009","journal-title":"Curr Opin Pedia"},{"issue":"12","key":"10.1016\/j.ctim.2025.103254_bib17","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1111\/j.1469-8749.2001.tb00171.x","article-title":"Management of constipation in children with disabilities","volume":"43","author":"Elawad","year":"2001","journal-title":"Dev Med Child Neurol"},{"issue":"11","key":"10.1016\/j.ctim.2025.103254_bib18","first-page":"34","article-title":"A national audit of chronic constipation in the community","volume":"99","author":"Addison","year":"2003","journal-title":"PubMed"},{"issue":"8","key":"10.1016\/j.ctim.2025.103254_bib19","doi-asserted-by":"crossref","first-page":"326","DOI":"10.12968\/bjcn.2006.11.8.21664","article-title":"A new look at constipation management in the community","volume":"11","author":"Emly","year":"2006","journal-title":"Br J Community Nurs"},{"issue":"8","key":"10.1016\/j.ctim.2025.103254_bib20","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.3390\/jcm10081669","article-title":"Neurogenic bowel dysfunction in children and adolescents","volume":"10","author":"Mosiello","year":"2021","journal-title":"J Clin Med"},{"key":"10.1016\/j.ctim.2025.103254_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.ctim.2020.102553","article-title":"The effect of abdominal massage on gastrointestinal functions: a systematic review","volume":"54","author":"Dehghan","year":"2020","journal-title":"Complement Ther Med"},{"issue":"1","key":"10.1016\/j.ctim.2025.103254_bib22","doi-asserted-by":"crossref","DOI":"10.1186\/s13634-021-00788-6","article-title":"Health efficacy of electrically operated automated massage on muscle properties, peripheral circulation, and physio-psychological variables: a narrative review","volume":"2021","author":"Paul","year":"2021","journal-title":"EURASIP J Adv Signal Process"},{"issue":"24","key":"10.1016\/j.ctim.2025.103254_bib23","first-page":"3764","article-title":"Meta-analysis on the clinical effect of massage therapy in treating infantile constipation","volume":"33","author":"Chen","year":"2018","journal-title":"Guangming J Chin Med"},{"issue":"4","key":"10.1016\/j.ctim.2025.103254_bib24","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.3390\/s21041192","article-title":"Abdominal stiffness evaluation in massage for constipation","volume":"21","author":"Wang","year":"2021","journal-title":"Sensors"},{"issue":"1","key":"10.1016\/j.ctim.2025.103254_bib25","first-page":"90","article-title":"The effectiveness of abdominal massage on neurogenic bowel dysfunction in patients with spinal cord injury: a systematic review]","volume":"64","author":"Wu","year":"2017","journal-title":"PubMed"},{"issue":"134","key":"10.1016\/j.ctim.2025.103254_bib26","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.jclinepi.2021.02.003","article-title":"Updating guidance for reporting systematic reviews: development of the PRISMA 2020 statement","volume":"134","author":"Page","year":"2021","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.ctim.2025.103254_bib27","unstructured":"Massage Techniques for Traditional Chinese Medicine (GB\/T 39511 - 2020) [Standard]. China Standards Press. 2020. Accessed December 31, 2024. \u3008https:\/\/openstd.samr.gov.cn\/bzgk\/gb\/newGbInfo?hcno=FBB427BF9B9F25832C1B6A65BDDDC887&refer=outter\u3009."},{"key":"10.1016\/j.ctim.2025.103254_bib28","unstructured":"WHO International Standard Terminologies on Traditional Chinese Medicine. \u3008www.who.int\u3009. 2022. \u3008https:\/\/www.who.int\/publications\/i\/item\/9789240042322\u3009."},{"issue":"6","key":"10.1016\/j.ctim.2025.103254_bib29","doi-asserted-by":"crossref","DOI":"10.1002\/jgh3.13102","article-title":"Comparison of the effects of abdominal massage and osteopathic manipulative treatment home program on constipation in children with cerebral palsy","volume":"8","author":"Chatip","year":"2024","journal-title":"JGH Open"},{"key":"10.1016\/j.ctim.2025.103254_bib30","series-title":"Pediatric Tuina","author":"Liu","year":"2023"},{"issue":"1","key":"10.1016\/j.ctim.2025.103254_bib31","doi-asserted-by":"crossref","first-page":"l4898","DOI":"10.1136\/bmj.l4898","article-title":"RoB 2: a revised tool for assessing risk of bias in randomised trials","volume":"366","author":"Sterne","year":"2019","journal-title":"BMJ"},{"issue":"355","key":"10.1016\/j.ctim.2025.103254_bib32","doi-asserted-by":"crossref","first-page":"i4919","DOI":"10.1136\/bmj.i4919","article-title":"ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions","volume":"355","author":"Sterne","year":"2016","journal-title":"BMJ"},{"key":"10.1016\/j.ctim.2025.103254_bib33","series-title":"Cochrane Handbook for Systematic Reviews of Interventions","author":"Cochrane","year":"2024"},{"issue":"07","key":"10.1016\/j.ctim.2025.103254_bib34","first-page":"525","article-title":"Observation of the clinical efficacy of Liu\u2019s pediatric massage therapy in treating constipation in children with cerebral palsy","volume":"36","author":"Chen","year":"2024","journal-title":"J Shanxi Univ Chin Med"},{"issue":"07","key":"10.1016\/j.ctim.2025.103254_bib35","first-page":"525","article-title":"Effect of enteral massage combined with lactulose on the frequency of bowel movements and stool characteristics in Chil-dren with cerebral palsy and constipation","volume":"36","author":"Dai","year":"2022","journal-title":"Mil Med J South China"},{"issue":"01","key":"10.1016\/j.ctim.2025.103254_bib36","first-page":"158","article-title":"Clinical observation of tuina therapy for idiopathic constipation in children with spastic cerebral palsy","volume":"40","author":"Feng","year":"2013","journal-title":"Liaoning J Tradit Chin Med"},{"issue":"21","key":"10.1016\/j.ctim.2025.103254_bib37","article-title":"Integrating routine nursing care with tuina therapy: efficacy evaluation for constipation management in children with cerebral palsy","volume":"8","author":"Liu","year":"2014","journal-title":"Chin J Mod Drug Appl"},{"issue":"11","key":"10.1016\/j.ctim.2025.103254_bib38","article-title":"Nursing efficacy of pediatric tuina therapy for constipation in children with cerebral palsy: a retrospective analysis","author":"Liu","year":"2018","journal-title":"Health Guide"},{"issue":"19","key":"10.1016\/j.ctim.2025.103254_bib39","first-page":"287","article-title":"Clinical efficacy analysis of integrated traditional Chinese and Western Medicine in improving constipation in children with cerebral palsy and motor dysfunction","volume":"30","author":"Luo","year":"2020","journal-title":"China Health Care Nutr"},{"key":"10.1016\/j.ctim.2025.103254_bib40","first-page":"52-52","article-title":"Combined nursing care and tuina therapy for constipation in children with cerebral palsy: a clinical efficacy evaluation","volume":"16","author":"Nian","year":"2015","journal-title":"Med Inf"},{"issue":"34","key":"10.1016\/j.ctim.2025.103254_bib41","first-page":"187","article-title":"Effectiveness of pediatric tuina therapy on constipation in children with cerebral palsy: an observational study","volume":"9","author":"Shen","year":"2019","journal-title":"Yiyao Qianyan"},{"key":"10.1016\/j.ctim.2025.103254_bib42","article-title":"Efficacy of tui na in idiopathic constipation in children with cerebral palsy: a randomized controlled clinical trial","volume":"12","author":"Wang","year":"2025","journal-title":"Front Pedia"},{"issue":"06","key":"10.1016\/j.ctim.2025.103254_bib43","first-page":"55","article-title":"Nursing observation of pediatric massage therapy in treating constipation for children with cerebral palsy","volume":"9","author":"Xie","year":"2013","journal-title":"J Pedia Tradit Chin Med"},{"issue":"2","key":"10.1016\/j.ctim.2025.103254_bib44","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1177\/1043454205285874","article-title":"A constipation assessment scale for use in pediatric oncology","volume":"23","author":"Woolery","year":"2006","journal-title":"J Pedia Oncol Nurs"},{"issue":"2","key":"10.1016\/j.ctim.2025.103254_bib45","first-page":"347","article-title":"Analysis of physique factors of constipation in the elderly","volume":"37","author":"Huang","year":"2023","journal-title":"Chin Nurs Res"},{"key":"10.1016\/j.ctim.2025.103254_bib46","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.brainres.2018.02.039","article-title":"The touchy business of gastrointestinal (GI) mechanosensitivity","volume":"1693","author":"Treichel","year":"2018","journal-title":"Brain Res"},{"issue":"1","key":"10.1016\/j.ctim.2025.103254_bib47","doi-asserted-by":"crossref","DOI":"10.1186\/s13063-021-05528-7","article-title":"Efficacy of abdomen-rubbing qigong exercise for chronic insomnia: study protocol for a randomized controlled trial","volume":"22","author":"Guan","year":"2021","journal-title":"Trials"},{"issue":"09","key":"10.1016\/j.ctim.2025.103254_bib48","first-page":"1593","article-title":"Efficacy of massage for the treatment of post-stroke constipation:a meta-analysis","volume":"20","author":"Liu","year":"2022","journal-title":"Chin J Gen Pr"},{"issue":"1","key":"10.1016\/j.ctim.2025.103254_bib49","doi-asserted-by":"crossref","DOI":"10.1186\/s40168-021-01165-z","article-title":"Intestinal microbiota shapes gut physiology and regulates enteric neurons and glia","volume":"9","author":"Vicentini","year":"2021","journal-title":"Microbiome"},{"issue":"10","key":"10.1016\/j.ctim.2025.103254_bib50","doi-asserted-by":"crossref","DOI":"10.1093\/procel\/pwad026","article-title":"The microbiota-gut-brain axis and neurodevelopmental disorders","volume":"14","author":"Wang","year":"2023","journal-title":"Protein Cell"},{"issue":"11","key":"10.1016\/j.ctim.2025.103254_bib51","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1038\/nrmicro2876","article-title":"The interplay between the intestinal microbiota and the brain","volume":"10","author":"Collins","year":"2012","journal-title":"Nat Rev Microbiol"},{"issue":"10","key":"10.1016\/j.ctim.2025.103254_bib52","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1038\/nrn3346","article-title":"Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour","volume":"13","author":"Cryan","year":"2012","journal-title":"Nat Rev Neurosci"}],"container-title":["Complementary Therapies in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S096522992500130X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S096522992500130X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T12:36:28Z","timestamp":1761827788000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S096522992500130X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":52,"alternative-id":["S096522992500130X"],"URL":"https:\/\/doi.org\/10.1016\/j.ctim.2025.103254","relation":{},"ISSN":["0965-2299"],"issn-type":[{"value":"0965-2299","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effectiveness of massage therapy for constipation in children with cerebral palsy: A systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Complementary Therapies in Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ctim.2025.103254","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"103254"}}