{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T23:58:01Z","timestamp":1762300681023,"version":"3.33.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T00:00:00Z","timestamp":1716336000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["ctro.science","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical and Translational Radiation Oncology"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.ctro.2024.100798","type":"journal-article","created":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T01:14:26Z","timestamp":1717204466000},"page":"100798","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Preoperative radiosurgery for brain metastases (PREOP-1): A feasibility trial"],"prefix":"10.1016","volume":"47","author":[{"given":"S","family":"Rogers","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Schwyzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Lomax","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Alonso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Lazeroms","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Gomez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Diahovets","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Fischer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Schwenne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Ademaj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Berkmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Tortora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Marbacher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Remonda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.A.","family":"Schubert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O","family":"Riesterer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ctro.2024.100798_b0005","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1001\/jama.2016.9839","article-title":"Effect of Radiosurgery Alone vs Radiosurgery With Whole Brain Radiation Therapy on Cognitive Function in Patients With 1 to 3 Brain Metastases: A Randomized Clinical Trial","volume":"316","author":"Brown","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.ctro.2024.100798_b0010","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/S1470-2045(09)70263-3","article-title":"Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomised controlled trial","volume":"10","author":"Chang","year":"2009","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ctro.2024.100798_b0015","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.ijrobp.2017.04.006","article-title":"Single-Fraction Stereotactic Radiosurgery (SRS) Alone Versus Surgical Resection and SRS for Large Brain Metastases: A Multi-institutional Analysis","volume":"99","author":"Prabhu","year":"2017","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ctro.2024.100798_b0020","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1016\/S1470-2045(17)30414-X","article-title":"Post-operative stereotactic radiosurgery versus observation for completely resected brain metastases: a single-centre, randomised, controlled, phase 3 trial","volume":"18","author":"Mahajan","year":"2017","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ctro.2024.100798_b0025","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/S1470-2045(17)30441-2","article-title":"Postoperative stereotactic radiosurgery compared with whole brain radiotherapy for resected metastatic brain disease (NCCTG N107C\/CEC.3): a multicentre, randomised, controlled, phase 3 trial","volume":"18","author":"Brown","year":"2017","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ctro.2024.100798_b0030","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1007\/s11060-017-2666-7","article-title":"Risk of leptomeningeal carcinomatosis in patients with brain metastases treated with stereotactic radiosurgery","volume":"136","author":"Ma","year":"2018","journal-title":"J Neurooncol"},{"key":"10.1016\/j.ctro.2024.100798_b0035","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.ijrobp.2013.07.034","article-title":"Risk of leptomeningeal disease in patients treated with stereotactic radiosurgery targeting the postoperative resection cavity for brain metastases","volume":"87","author":"Atalar","year":"2013","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ctro.2024.100798_b0040","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1227\/NEU.0000000000000626","article-title":"Tumor progression in patients receiving adjuvant whole-brain radiotherapy vs localized radiotherapy after surgical resection of brain metastases","volume":"76","author":"Hsieh","year":"2015","journal-title":"Neurosurgery"},{"key":"10.1016\/j.ctro.2024.100798_b0045","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1002\/cam4.206","article-title":"Gamma Knife radiosurgery to four or more brain metastases in patients without prior intracranial radiation or surgery","volume":"3","author":"Ojerholm","year":"2014","journal-title":"Cancer Med"},{"key":"10.1016\/j.ctro.2024.100798_b0050","doi-asserted-by":"crossref","DOI":"10.1007\/s11060-021-03840-5","article-title":"Five fraction stereotactic radiotherapy after brain metastasectomy: a single-institution experience and literature review","author":"Rogers","year":"2021","journal-title":"J Neurooncol"},{"key":"10.1016\/j.ctro.2024.100798_b0055","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.ijrobp.2017.09.047","article-title":"Consensus Contouring Guidelines for Postoperative Completely Resected Cavity Stereotactic Radiosurgery for Brain Metastases","volume":"100","author":"Soliman","year":"2018","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ctro.2024.100798_b0060","doi-asserted-by":"crossref","first-page":"984","DOI":"10.3171\/2012.1.JNS111560","article-title":"Risk for leptomeningeal seeding after resection for brain metastases: implication of tumor location with mode of resection","volume":"116","author":"Ahn","year":"2012","journal-title":"J Neurosurg"},{"key":"10.1016\/j.ctro.2024.100798_b0065","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1007\/s11060-016-2334-3","article-title":"Comparing pre-operative stereotactic radiosurgery (SRS) to post-operative whole brain radiation therapy (WBRT) for resectable brain metastases: a multi-institutional analysis","volume":"131","author":"Patel","year":"2017","journal-title":"J Neurooncol"},{"key":"10.1016\/j.ctro.2024.100798_b0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijrobp.2021.05.124","article-title":"Preoperative Radiosurgery for Resected Brain Metastases: The PROPS-BM Multicenter Cohort Study","author":"Prabhu","year":"2021","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ctro.2024.100798_b0075","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.wneu.2023.10.131","article-title":"Preoperative Versus Postoperative Radiosurgery of Brain Metastases: A Meta-Analysis","volume":"182","author":"Dharnipragada","year":"2024","journal-title":"World Neurosurg"},{"key":"10.1016\/j.ctro.2024.100798_b0080","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.ijrobp.2023.09.012","article-title":"Single-Fraction Versus Fractionated Preoperative Radiosurgery for Resected Brain Metastases: A PROPS-BM International Multicenter Cohort Study","volume":"118","author":"Prabhu","year":"2024","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ctro.2024.100798_b0085","article-title":"The Effect of Slice Thickness on Contours of Brain Metastases for Stereotactic Radiosurgery","volume":"6","author":"Thrower","year":"2021","journal-title":"Adv Radiat Oncol"},{"key":"10.1016\/j.ctro.2024.100798_b0090","article-title":"Preoperative stereotactic radiosurgery before planned resection of brain metastases: updated analysis of efficacy and toxicity of a novel treatment paradigm","volume":"1\u20138","author":"Prabhu","year":"2018","journal-title":"J Neurosurg"},{"key":"10.1016\/j.ctro.2024.100798_b0095","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.ijrobp.2008.04.026","article-title":"Conformity of LINAC-based stereotactic radiosurgery using dynamic conformal arcs and micro-multileaf collimator","volume":"73","author":"Hazard","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ctro.2024.100798_b0100","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1093\/jnci\/85.5.365","article-title":"The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology","volume":"85","author":"Aaronson","year":"1993","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.ctro.2024.100798_b0105","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/j.ejca.2010.01.012","article-title":"An international validation study of the EORTC brain cancer module (EORTC QLQ-BN20) for assessing health-related quality of life and symptoms in brain cancer patients","volume":"46","author":"Taphoorn","year":"2010","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.ctro.2024.100798_b0110","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.radonc.2019.08.024","article-title":"Post-operative stereotactic radiosurgery following excision of brain metastases: A systematic review and meta-analysis","volume":"142","author":"Akanda","year":"2020","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ctro.2024.100798_b0115","first-page":"23","article-title":"Significant tumor shift in patients treated with stereotactic radiosurgery for brain metastasis","volume":"2","author":"Hessen","year":"2017","journal-title":"Clin Transl Radiat Oncol"},{"key":"10.1016\/j.ctro.2024.100798_b0120","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/S0360-3016(99)00507-6","article-title":"Single dose radiosurgical treatment of recurrent previously irradiated primary brain tumors and brain metastases: final report of RTOG protocol 90\u201305","volume":"47","author":"Shaw","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ctro.2024.100798_b0125","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.ijrobp.2020.08.013","article-title":"Single- and Multifraction Stereotactic Radiosurgery Dose\/Volume Tolerances of the Brain","volume":"110","author":"Milano","year":"2021","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ctro.2024.100798_b0130","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s10585-018-9896-8","article-title":"Potential impact of invasive surgical procedures on primary tumor growth and metastasis","volume":"35","author":"Alieva","year":"2018","journal-title":"Clin Exp Metastasis"},{"key":"10.1016\/j.ctro.2024.100798_b0135","doi-asserted-by":"crossref","first-page":"4567","DOI":"10.1038\/s41598-022-08507-3","article-title":"Evaluation of the impact of pre-operative stereotactic radiotherapy on the acute changes in histopathologic and immune marker profiles of brain metastases","volume":"12","author":"Kotecha","year":"2022","journal-title":"Sci Rep"},{"key":"10.1016\/j.ctro.2024.100798_b0140","doi-asserted-by":"crossref","first-page":"1056330","DOI":"10.3389\/fonc.2023.1056330","article-title":"What if: A retrospective reconstruction of resection cavity stereotactic radiosurgery to mimic neoadjuvant stereotactic radiosurgery","volume":"13","author":"Acker","year":"2023","journal-title":"Front Oncol"},{"key":"10.1016\/j.ctro.2024.100798_b0145","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.ijrobp.2013.07.022","article-title":"The tumor radiobiology of SRS and SBRT: are more than the 5 Rs involved?","volume":"88","author":"Brown","year":"2014","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ctro.2024.100798_b0150","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/j.ijrobp.2014.03.043","article-title":"Is indirect cell death involved in response of tumors to stereotactic radiosurgery and stereotactic body radiation therapy?","volume":"89","author":"Song","year":"2014","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ctro.2024.100798_b0155","article-title":"Single Fraction vs. Fractionated Preoperative Radiosurgery for Resected Brain Metastases: a PROPS-BM International Multicenter Cohort Study","author":"Prabhu","year":"2023","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["Clinical and Translational Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405630824000752?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405630824000752?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T23:45:40Z","timestamp":1737675940000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405630824000752"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":31,"alternative-id":["S2405630824000752"],"URL":"https:\/\/doi.org\/10.1016\/j.ctro.2024.100798","relation":{},"ISSN":["2405-6308"],"issn-type":[{"type":"print","value":"2405-6308"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Preoperative radiosurgery for brain metastases (PREOP-1): A feasibility trial","name":"articletitle","label":"Article Title"},{"value":"Clinical and Translational Radiation Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ctro.2024.100798","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V. on behalf of European Society for Radiotherapy and Oncology.","name":"copyright","label":"Copyright"}],"article-number":"100798"}}