{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:25:59Z","timestamp":1786987559616,"version":"build-2736575974"},"reference-count":66,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,5,14]],"date-time":"2018-05-14T00:00:00Z","timestamp":1526256000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","cancertreatmentreviews.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cancer Treatment Reviews"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1016\/j.ctrv.2018.05.008","type":"journal-article","created":{"date-parts":[[2018,6,26]],"date-time":"2018-06-26T12:12:38Z","timestamp":1530015158000},"page":"136-144","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"special_numbering":"C","title":["Does pelvic radiation increase rectal cancer incidence? \u2013 A systematic review and meta-analysis"],"prefix":"10.1016","volume":"68","author":[{"given":"A.J.M.","family":"Rombouts","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Hugen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.J.P.","family":"van Beek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.M.P.","family":"Poortmans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.H.W.","family":"de Wilt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.D.","family":"Nagtegaal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ctrv.2018.05.008_b0005","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1002\/cncr.21324","article-title":"The role of radiotherapy in cancer treatment: estimating optimal utilization from a review of evidence-based clinical guidelines","volume":"104","author":"Delaney","year":"2005","journal-title":"Cancer"},{"key":"10.1016\/j.ctrv.2018.05.008_b0010","doi-asserted-by":"crossref","first-page":"24","DOI":"10.3389\/fmolb.2014.00024","article-title":"Biological response of cancer cells to radiation treatment","volume":"1","author":"Baskar","year":"2014","journal-title":"Front Mol Biosci"},{"key":"10.1016\/j.ctrv.2018.05.008_b0015","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1136\/jclinpath-2014-202494","article-title":"Predictive markers of radiotherapy-induced rectal cancer regression","volume":"67","author":"Shin","year":"2014","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.ctrv.2018.05.008_b0020","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/S1470-2045(11)70097-3","article-title":"Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer: 12-year follow-up of the multicentre, randomised controlled TME trial","volume":"12","author":"van Gijn","year":"2011","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ctrv.2018.05.008_b0025","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1097\/COC.0b013e318271b1aa","article-title":"Management of radiation proctitis","volume":"37","author":"Mendenhall","year":"2014","journal-title":"Am J Clin Oncol"},{"key":"10.1016\/j.ctrv.2018.05.008_b0030","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.brachy.2014.03.002","article-title":"High-dose-rate brachytherapy as monotherapy for prostate cancer","volume":"13","author":"Demanes","year":"2014","journal-title":"Brachytherapy"},{"key":"10.1016\/j.ctrv.2018.05.008_b0035","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.ijrobp.2009.11.041","article-title":"Overall survival benefit from postoperative radiation therapy for organ-confined, margin-positive prostate cancer","volume":"79","author":"Dillman","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ctrv.2018.05.008_b0040","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1080\/02841860310014660","article-title":"A systematic overview of radiation therapy effects in cervical cancer (cervix uteri)","volume":"42","author":"Einhorn","year":"2003","journal-title":"Acta Oncol"},{"key":"10.1016\/j.ctrv.2018.05.008_b0045","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1053\/j.gastro.2004.12.038","article-title":"Increased risk of rectal cancer after prostate radiation: a population-based study","volume":"128","author":"Baxter","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.ctrv.2018.05.008_b0050","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.radonc.2005.04.003","article-title":"Adverse effects after radiotherapy for early stage (I, IIa, IIb) seminoma","volume":"76","author":"Majewski","year":"2005","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ctrv.2018.05.008_b0055","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1002\/1097-0142(19950801)76:3<442::AID-CNCR2820760315>3.0.CO;2-L","article-title":"Second primary cancer after treatment for cervical cancer. An international cancer registries study","volume":"76","author":"Kleinerman","year":"1995","journal-title":"Cancer"},{"key":"10.1016\/j.ctrv.2018.05.008_b0060","first-page":"219","article-title":"Summary: multiple primary cancers in Connecticut, 1935\u201382","volume":"68","author":"Curtis","year":"1985","journal-title":"Natl Cancer Inst Monogr"},{"key":"10.1016\/j.ctrv.2018.05.008_b0065","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1200\/JCO.2014.58.6693","article-title":"No increased risk of second cancer after radiotherapy in patients treated for rectal or endometrial cancer in the randomized TME, PORTEC-1, and PORTEC-2 trials","volume":"33","author":"Wiltink","year":"2015","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ctrv.2018.05.008_b0070","doi-asserted-by":"crossref","first-page":"4510","DOI":"10.1200\/JCO.2011.35.0991","article-title":"Prostate brachytherapy and second primary cancer risk: a competitive risk analysis","volume":"29","author":"Hinnen","year":"2011","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ctrv.2018.05.008_b0075","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1093\/annonc\/mdw661","article-title":"Incidence of second tumors after treatment with or without radiation for rectal cancer","volume":"28","author":"Rombouts","year":"2017","journal-title":"Ann Oncol"},{"key":"10.1016\/j.ctrv.2018.05.008_b0080","doi-asserted-by":"crossref","first-page":"145","DOI":"10.3109\/02841868509134378","article-title":"Cohort study of the long-term effect of irradiation for carcinoma of the uterine cervix. Second primary malignancies in the pelvic organs in women irradiated for cervical carcinoma at Radiumhemmet 1914\u20131965","volume":"24","author":"Pettersson","year":"1985","journal-title":"Acta Radiol Oncol"},{"key":"10.1016\/j.ctrv.2018.05.008_b0085","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/j.juro.2006.10.071","article-title":"Bladder cancer incidence and risk factors in men with prostate cancer: results from cancer of the prostate strategic urologic research endeavor","volume":"177","author":"Boorjian","year":"2007","journal-title":"J Urol"},{"key":"10.1016\/j.ctrv.2018.05.008_b0090","unstructured":"Wells GA, Shea B, O'Connell D, Peterson J, Welch V, Losos M, Tugwell P. Newcastle \u2013 Ottawa quality assessment scale for cohort studies [Internet]; 2014 [cited 11 August 2017]. Available from http:\/\/www.ohri.ca\/programs\/clinical_epidemiology\/oxford.asp."},{"key":"10.1016\/j.ctrv.2018.05.008_b0095","unstructured":"Review Manager (RevMan) [Computer program]. Version 5.3. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration; 2014."},{"key":"10.1016\/j.ctrv.2018.05.008_b0100","unstructured":"Rombouts Anouk JM, van Beek Jasper, Hugen Niek, Poortmans Philip MD, de Wilt Johannes HW, Nagtegaal Iris D. Radiation therapy-induced rectal cancer: a systematic review. PROSPERO 2017 CRD42017046045 Available from: http:\/\/www.crd.york.ac.uk\/PROSPERO\/display_record.php?ID=CRD42017046045."},{"key":"10.1016\/j.ctrv.2018.05.008_b0105","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1002\/1097-0142(19910115)67:2<398::AID-CNCR2820670214>3.0.CO;2-A","article-title":"Second cancer after radiation therapy for cancer of the uterine cervix","volume":"67","author":"Arai","year":"1991","journal-title":"Cancer"},{"key":"10.1016\/j.ctrv.2018.05.008_b0110","first-page":"553","article-title":"Second primary cancer following treatment for cervical cancer","volume":"131","author":"Clarke","year":"1984","journal-title":"Can Med Assoc J"},{"key":"10.1016\/j.ctrv.2018.05.008_b0115","first-page":"181","article-title":"Occurrence of second primary cancers among patients with cervical cancer in Osaka, Japan","volume":"69","author":"Hiyama","year":"1985","journal-title":"Natl Cancer Inst Monogr"},{"key":"10.1016\/j.ctrv.2018.05.008_b0120","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1038\/bjc.1989.93","article-title":"Subsequent primary cancers in relation to treatment of ovarian cancer","volume":"59","author":"Prior","year":"1989","journal-title":"Br J Cancer"},{"key":"10.1016\/j.ctrv.2018.05.008_b0125","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1093\/jnci\/61.5.1195","article-title":"Second primary neoplasms following ovarian cancer","volume":"61","author":"Reimer","year":"1978","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.ctrv.2018.05.008_b0130","article-title":"New malignancies following cancer of the uterine corpus and ovary","author":"Freedman","year":"2006"},{"key":"10.1016\/j.ctrv.2018.05.008_b0135","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1158\/1055-9965.EPI-09-0241","article-title":"Association of colorectal cancer and prostate cancer and impact of radiation therapy","volume":"18","author":"Huo","year":"2009","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.ctrv.2018.05.008_b0140","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1200\/JCO.2009.26.0133","article-title":"Time trends and local variation in primary treatment of localized prostate cancer","volume":"28","author":"Cooperberg","year":"2010","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ctrv.2018.05.008_b0145","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.3109\/0284186X.2015.1061691","article-title":"Risk of radiation-induced secondary rectal and bladder cancer following radiotherapy of prostate cancer","volume":"54","author":"Stokkevag","year":"2015","journal-title":"Acta Oncol"},{"key":"10.1016\/j.ctrv.2018.05.008_b0150","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1002\/ijc.23601","article-title":"Increased risk of colon cancer after external radiation therapy for prostate cancer","volume":"123","author":"Rapiti","year":"2008","journal-title":"Int J Cancer"},{"key":"10.1016\/j.ctrv.2018.05.008_b0155","doi-asserted-by":"crossref","first-page":"e0140693","DOI":"10.1371\/journal.pone.0140693","article-title":"Risk of second primary cancer among prostate cancer patients in Korea: a population-based cohort study","volume":"10","author":"Joung","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.ctrv.2018.05.008_b0160","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.ijrobp.2009.02.011","article-title":"The rate of secondary malignancies after radical prostatectomy versus external beam radiation therapy for localized prostate cancer: a population-based study on 17,845 patients","volume":"76","author":"Bhojani","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ctrv.2018.05.008_b0165","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1097\/SLA.0b013e3182382fd5","article-title":"Radiation therapy for prostate cancer increases the risk of subsequent rectal cancer","volume":"254","author":"Margel","year":"2011","journal-title":"Ann Surg"},{"key":"10.1016\/j.ctrv.2018.05.008_b0170","doi-asserted-by":"crossref","first-page":"2735","DOI":"10.1002\/cncr.28769","article-title":"Risk of second primary tumors in men diagnosed with prostate cancer: a population-based cohort study","volume":"120","author":"Davis","year":"2014","journal-title":"Cancer"},{"key":"10.1016\/j.ctrv.2018.05.008_b0175","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/j.ijrobp.2014.07.032","article-title":"Incidence of second malignancies in prostate cancer patients treated with low-dose-rate brachytherapy and radical prostatectomy","volume":"90","author":"Hamilton","year":"2014","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ctrv.2018.05.008_b0180","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.ijrobp.2005.11.013","article-title":"Prostatic irradiation is not associated with any measurable increase in the risk of subsequent rectal cancer","volume":"65","author":"Kendal","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ctrv.2018.05.008_b0185","series-title":"New malignancies among cancer survivors: SEER cancer registries, 1973\u20132000","first-page":"207","article-title":"New malignancies following cancer of the Cervix Uteri, Vagina, and Vulva","author":"Kleinerman","year":"2006"},{"key":"10.1016\/j.ctrv.2018.05.008_b0190","doi-asserted-by":"crossref","first-page":"3","DOI":"10.2307\/3577477","article-title":"Radiation dose and second cancer risk in patients treated for cancer of the cervix","volume":"116","author":"Boice","year":"1988","journal-title":"Radiat Res"},{"issue":"Suppl 24","key":"10.1016\/j.ctrv.2018.05.008_b0195","doi-asserted-by":"crossref","first-page":"5119","DOI":"10.1002\/cncr.30906","article-title":"Cervical cancer survival in the United States by race and stage (2001\u20132009): Findings from the CONCORD-2 study","volume":"123","author":"Benard","year":"2017","journal-title":"Cancer"},{"key":"10.1016\/j.ctrv.2018.05.008_b0200","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1007\/s12032-014-0943-2","article-title":"Risk of colorectal cancer among long-term cervical cancer survivors","volume":"31","author":"Rodriguez","year":"2014","journal-title":"Med Oncol"},{"key":"10.1016\/j.ctrv.2018.05.008_b0205","first-page":"955","article-title":"Second cancers following radiation treatment for cervical cancer. An international collaboration among cancer registries","volume":"74","author":"Boice","year":"1985","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.ctrv.2018.05.008_b0210","series-title":"New malignancies among cancer survivors: SEER cancer registries","first-page":"1973","article-title":"New malignancies following cancer of the uterine corpus and ovary","author":"Freedman","year":"2006"},{"key":"10.1016\/j.ctrv.2018.05.008_b0215","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1097\/AOG.0b013e318264f794","article-title":"Ten-year relative survival for epithelial ovarian cancer","volume":"120","author":"Baldwin","year":"2012","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ctrv.2018.05.008_b0220","unstructured":"Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, et al., editors. SEER Cancer Statistics Review, 1975-2012, National Cancer Institute. Bethesda, MD, http:\/\/seer.cancer.gov\/csr\/1975_2012\/, based on November 2014 SEER data submission, posted to the SEER web site, April 2015."},{"key":"10.1016\/j.ctrv.2018.05.008_b0225","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1016\/j.ejca.2009.01.006","article-title":"Long-term morbidity of adjuvant whole abdominal radiotherapy (WART) or chemotherapy for early stage ovarian cancer","volume":"45","author":"Engelen","year":"2009","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.ctrv.2018.05.008_b0230","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.ijrobp.2006.05.016","article-title":"Second malignancies after prostate brachytherapy: incidence of bladder and colorectal cancers in patients with 15 years of potential follow-up","volume":"66","author":"Liauw","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ctrv.2018.05.008_b0235","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1016\/j.juro.2008.07.038","article-title":"Radiation therapy for prostate cancer increases subsequent risk of bladder and rectal cancer: a population based cohort study","volume":"180","author":"Nieder","year":"2008","journal-title":"J Urol"},{"key":"10.1016\/j.ctrv.2018.05.008_b0240","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.ijrobp.2014.10.040","article-title":"Risk of second cancers according to radiation therapy technique and modality in prostate cancer survivors","volume":"91","author":"Berrington de Gonzalez","year":"2015","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ctrv.2018.05.008_b0245","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1158\/1055-9965.EPI-09-0892","article-title":"Comparison of second cancer risks from brachytherapy and external beam therapy after uterine corpus cancer","volume":"19","author":"Lonn","year":"2010","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.ctrv.2018.05.008_b0250","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.ijrobp.2009.07.1692","article-title":"A population-based study of subsequent primary malignancies after endometrial cancer: genetic, environmental, and treatment-related associations","volume":"78","author":"Brown","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ctrv.2018.05.008_b0255","series-title":"New malignancies following cancer of the male genital tract","author":"McMaster","year":"2006"},{"key":"10.1016\/j.ctrv.2018.05.008_b0260","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0959-8049(96)00458-3","article-title":"Risk of subsequent non-germ cell cancer after treatment of germ cell cancer in 2006 Norwegian male patients","volume":"33","author":"Wanderas","year":"1997","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.ctrv.2018.05.008_b0265","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1038\/bjc.1990.142","article-title":"Second non-germ cell malignancies after radiotherapy of testicular cancer with or without chemotherapy","volume":"61","author":"Fossa","year":"1990","journal-title":"Br J Cancer"},{"key":"10.1016\/j.ctrv.2018.05.008_b0270","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1080\/09553009414550161","article-title":"Conformal radiotherapy at the Royal Marsden Hospital (UK)","volume":"65","author":"Horwich","year":"1994","journal-title":"Int J Radiat Biol"},{"key":"10.1016\/j.ctrv.2018.05.008_b0275","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0360-3016(82)90514-4","article-title":"Subsequent malignancies associated with carcinoma of the uterine cervix: including an analysis of the effect of patient and treatment parameters on incidence and sites of metachronous malignancies","volume":"8","author":"Kapp","year":"1982","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ctrv.2018.05.008_b0280","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1111\/j.1464-410X.2011.10424.x","article-title":"Incidence of second malignancies after external beam radiotherapy for clinical stage I testicular seminoma","volume":"109","author":"Lewinshtein","year":"2012","journal-title":"BJU Int"},{"key":"10.1016\/j.ctrv.2018.05.008_b0285","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.radonc.2008.02.021","article-title":"Reirradiation, surgery and IORT for recurrent rectal cancer in previously irradiated patients","volume":"87","author":"Vermaas","year":"2008","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ctrv.2018.05.008_b0290","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1097\/DCR.0000000000000547","article-title":"Treatment of locally recurrent rectal carcinoma in previously (chemo)irradiated patients: a review","volume":"59","author":"van der Meij","year":"2016","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.ctrv.2018.05.008_b0295","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.radonc.2017.02.007","article-title":"Secondary malignancies after rectal cancer resection with and without radiation therapy: A propensity-adjusted, population-based SEER analysis","volume":"123","author":"Warschkow","year":"2017","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ctrv.2018.05.008_b0300","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1097\/01.coc.0000258084.55036.9e","article-title":"A population-based analysis of second primary cancers after irradiation for rectal cancer","volume":"30","author":"Kendal","year":"2007","journal-title":"Am J Clin Oncol"},{"key":"10.1016\/j.ctrv.2018.05.008_b0305","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1002\/cncr.23241","article-title":"External beam radiation treatment for rectal cancer is associated with a decrease in subsequent prostate cancer diagnosis","volume":"112","author":"Hoffman","year":"2008","journal-title":"Cancer"},{"key":"10.1016\/j.ctrv.2018.05.008_b0310","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1016\/j.ijrobp.2006.07.1386","article-title":"Radiation proctopathy in the treatment of prostate cancer","volume":"66","author":"Garg","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ctrv.2018.05.008_b0315","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1046\/j.1463-1318.2003.00510.x","article-title":"Anal and rectal cancer in Crohn's disease","volume":"5","author":"Sjodahl","year":"2003","journal-title":"Colorectal Dis"},{"key":"10.1016\/j.ctrv.2018.05.008_b0320","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1002\/(SICI)1097-0142(19971101)80:9<1875::AID-CNCR29>3.0.CO;2-1","article-title":"Results of hospital cancer registry surveys by the American College of Surgeons: outcomes of prostate cancer treatment by radical prostatectomy","volume":"80","author":"Mettlin","year":"1997","journal-title":"Cancer"},{"issue":"1","key":"10.1016\/j.ctrv.2018.05.008_b0325","doi-asserted-by":"crossref","DOI":"10.1186\/s13014-016-0738-z","article-title":"Risk of second cancer following radiotherapy for prostate cancer: A population-based analysis","volume":"12","author":"Hegemann","year":"2017","journal-title":"Radiation Oncol"},{"key":"10.1016\/j.ctrv.2018.05.008_b0330","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1002\/1097-0142(19880215)61:4<679::AID-CNCR2820610411>3.0.CO;2-S","article-title":"Second primary cancer after treatment for cervical cancer. Late effects after radiotherapy","volume":"61","author":"Storm","year":"1988","journal-title":"Cancer."}],"container-title":["Cancer Treatment Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030573721830077X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030573721830077X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,11,4]],"date-time":"2020-11-04T04:52:31Z","timestamp":1604465551000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S030573721830077X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":66,"alternative-id":["S030573721830077X"],"URL":"https:\/\/doi.org\/10.1016\/j.ctrv.2018.05.008","relation":{},"ISSN":["0305-7372"],"issn-type":[{"value":"0305-7372","type":"print"}],"subject":[],"published":{"date-parts":[[2018,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Does pelvic radiation increase rectal cancer incidence? \u2013 A systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Cancer Treatment Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ctrv.2018.05.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}