{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T07:59:40Z","timestamp":1791187180380,"version":"4.1.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"17","license":[{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,8,22]],"date-time":"2013-08-22T00:00:00Z","timestamp":1377129600000},"content-version":"vor","delay-in-days":721,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100014185","name":"Searle Scholars Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014185","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["F31NS060341"],"award-info":[{"award-number":["F31NS060341"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NS061908"],"award-info":[{"award-number":["NS061908"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006211","name":"Klingenstein Third Generation Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006211","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Biology"],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1016\/j.cub.2011.07.040","type":"journal-article","created":{"date-parts":[[2011,8,27]],"date-time":"2011-08-27T00:53:19Z","timestamp":1314406399000},"page":"1480-1487","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"title":["Dscam1-Mediated Self-Avoidance Counters Netrin-Dependent Targeting of Dendrites in Drosophila"],"prefix":"10.1016","volume":"21","author":[{"given":"Benjamin\u00a0J.","family":"Matthews","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wesley\u00a0B.","family":"Grueber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cub.2011.07.040_bib1","doi-asserted-by":"crossref","first-page":"a001750","DOI":"10.1101\/cshperspect.a001750","article-title":"Self-avoidance and tiling: Mechanisms of dendrite and axon spacing","volume":"2","author":"Grueber","year":"2010","journal-title":"Cold Spring Harb Perspect Biol"},{"key":"10.1016\/j.cub.2011.07.040_bib2","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/1756-6606-3-28","article-title":"Molecular mechanisms of tiling and self-avoidance in neural development","volume":"3","author":"Cameron","year":"2010","journal-title":"Mol. Brain"},{"key":"10.1016\/j.cub.2011.07.040_bib3","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/S0092-8674(00)80878-8","article-title":"Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity","volume":"101","author":"Schmucker","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.cub.2011.07.040_bib4","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/j.neuron.2004.07.020","article-title":"Analysis of Dscam diversity in regulating axon guidance in Drosophila mushroom bodies","volume":"43","author":"Zhan","year":"2004","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2011.07.040_bib5","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/S0896-6273(02)00570-6","article-title":"Drosophila Dscam is required for divergent segregation of sister branches and suppresses ectopic bifurcation of axons","volume":"33","author":"Wang","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2011.07.040_bib6","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.neuron.2004.06.033","article-title":"Transmembrane\/juxtamembrane domain-dependent Dscam distribution and function during mushroom body neuronal morphogenesis","volume":"43","author":"Wang","year":"2004","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2011.07.040_bib7","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/nature06099","article-title":"Dscam diversity is essential for neuronal wiring and self-recognition","volume":"449","author":"Hattori","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.cub.2011.07.040_bib8","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/nn1652","article-title":"Dendritic patterning by Dscam and synaptic partner matching in the Drosophila antennal lobe","volume":"9","author":"Zhu","year":"2006","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.cub.2011.07.040_bib9","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.cell.2007.04.013","article-title":"Dendrite self-avoidance is controlled by Dscam","volume":"129","author":"Matthews","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.cub.2011.07.040_bib10","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.neuron.2007.03.029","article-title":"Drosophila sensory neurons require Dscam for dendritic self-avoidance and proper dendritic field organization","volume":"54","author":"Soba","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2011.07.040_bib11","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.neuron.2007.04.013","article-title":"Homophilic Dscam interactions control complex dendrite morphogenesis","volume":"54","author":"Hughes","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2011.07.040_bib12","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.neuron.2009.09.027","article-title":"DSCAM and DSCAML1 function in self-avoidance in multiple cell types in the developing mouse retina","volume":"64","author":"Fuerst","year":"2009","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2011.07.040_bib13","doi-asserted-by":"crossref","first-page":"2867","DOI":"10.1242\/dev.129.12.2867","article-title":"Tiling of the Drosophila epidermis by multidendritic sensory neurons","volume":"129","author":"Grueber","year":"2002","journal-title":"Development"},{"key":"10.1016\/j.cub.2011.07.040_bib14","series-title":"Comprehensive Insect Physiology, Biochemistry and Pharmacology","first-page":"71","article-title":"Mechanoreception","author":"McIver","year":"1985"},{"key":"10.1016\/j.cub.2011.07.040_bib15","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.cell.2004.08.021","article-title":"Alternative splicing of Drosophila Dscam generates axon guidance receptors that exhibit isoform-specific homophilic binding","volume":"118","author":"Wojtowicz","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.cub.2011.07.040_bib16","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1016\/j.cell.2007.08.026","article-title":"A vast repertoire of Dscam binding specificities arises from modular interactions of variable Ig domains","volume":"130","author":"Wojtowicz","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.cub.2011.07.040_bib17","doi-asserted-by":"crossref","first-page":"3839","DOI":"10.1242\/dev.023739","article-title":"Dscam guides embryonic axons by Netrin-dependent and -independent functions","volume":"135","author":"Andrews","year":"2008","journal-title":"Development"},{"key":"10.1016\/j.cub.2011.07.040_bib18","doi-asserted-by":"crossref","first-page":"2951","DOI":"10.1073\/pnas.0811083106","article-title":"DSCAM functions as a netrin receptor in commissural axon pathfinding","volume":"106","author":"Liu","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cub.2011.07.040_bib19","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1016\/j.cell.2008.05.030","article-title":"DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1","volume":"133","author":"Ly","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.cub.2011.07.040_bib20","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1038\/nn1625","article-title":"Netrins guide Drosophila commissural axons at short range","volume":"9","author":"Brankatschk","year":"2006","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.cub.2011.07.040_bib21","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0092-8674(00)81337-9","article-title":"UNC-40, a C. elegans homolog of DCC (Deleted in Colorectal Cancer), is required in motile cells responding to UNC-6 netrin cues","volume":"87","author":"Chan","year":"1996","journal-title":"Cell"},{"key":"10.1016\/j.cub.2011.07.040_bib22","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0092-8674(00)81336-7","article-title":"Deleted in Colorectal Cancer (DCC) encodes a netrin receptor","volume":"87","author":"Keino-Masu","year":"1996","journal-title":"Cell"},{"key":"10.1016\/j.cub.2011.07.040_bib23","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/S0896-6273(01)00505-0","article-title":"Short- and long-range repulsion by the Drosophila Unc5 netrin receptor","volume":"32","author":"Keleman","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2011.07.040_bib24","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0092-8674(00)81338-0","article-title":"Frazzled encodes a Drosophila member of the DCC immunoglobulin subfamily and is required for CNS and motor axon guidance","volume":"87","author":"Kolodziej","year":"1996","journal-title":"Cell"},{"key":"10.1016\/j.cub.2011.07.040_bib25","doi-asserted-by":"crossref","first-page":"13328","DOI":"10.1523\/JNEUROSCI.2858-06.2006","article-title":"Netrin\/DCC signaling controls contralateral dendrites of octavolateralis efferent neurons","volume":"26","author":"Suli","year":"2006","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.cub.2011.07.040_bib26","doi-asserted-by":"crossref","first-page":"4325","DOI":"10.1242\/dev.012872","article-title":"Cytoplasmic domain requirements for Frazzled-mediated attractive axon turning at the Drosophila midline","volume":"134","author":"Garbe","year":"2007","journal-title":"Development"},{"key":"10.1016\/j.cub.2011.07.040_bib27","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.ijdevneu.2008.07.004","article-title":"Frazzled cytoplasmic P-motifs are differentially required for axon pathway formation in the Drosophila embryonic CNS","volume":"26","author":"Dorsten","year":"2008","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.cub.2011.07.040_bib28","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0896-6273(00)80154-3","article-title":"Guidance cues at the Drosophila CNS midline: Identification and characterization of two Drosophila Netrin\/UNC-6 homologs","volume":"17","author":"Harris","year":"1996","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2011.07.040_bib29","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0896-6273(00)80153-1","article-title":"Genetic analysis of Netrin genes in Drosophila: Netrins guide CNS commissural axons and peripheral motor axons","volume":"17","author":"Mitchell","year":"1996","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2011.07.040_bib30","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/nature05382","article-title":"Specialized hepatocyte-like cells regulate Drosophila lipid metabolism","volume":"445","author":"Gutierrez","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.cub.2011.07.040_bib31","doi-asserted-by":"crossref","first-page":"e1000199","DOI":"10.1371\/journal.pbio.1000199","article-title":"Dendritic targeting in the leg neuropil of Drosophila: The role of midline signalling molecules in generating a myotopic map","volume":"7","author":"Brierley","year":"2009","journal-title":"PLoS Biol."},{"key":"10.1016\/j.cub.2011.07.040_bib32","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/nn1017","article-title":"Robo and Frazzled\/DCC mediate dendritic guidance at the CNS midline","volume":"6","author":"Furrer","year":"2003","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.cub.2011.07.040_bib33","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.cub.2006.11.067","article-title":"Intrinsic control of precise dendritic targeting by an ensemble of transcription factors","volume":"17","author":"Komiyama","year":"2007","journal-title":"Curr. Biol."},{"key":"10.1016\/j.cub.2011.07.040_bib34","doi-asserted-by":"crossref","first-page":"e1000200","DOI":"10.1371\/journal.pbio.1000200","article-title":"Midline signalling systems direct the formation of a neural map by dendritic targeting in the Drosophila motor system","volume":"7","author":"Mauss","year":"2009","journal-title":"PLoS Biol."},{"key":"10.1016\/j.cub.2011.07.040_bib35","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1038\/35007001","article-title":"Semaphorin 3A is\u00a0a chemoattractant for cortical apical dendrites","volume":"404","author":"Polleux","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.cub.2011.07.040_bib36","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/j.cell.2008.07.042","article-title":"A double S shape provides the structural basis for the extraordinary binding specificity of Dscam isoforms","volume":"134","author":"Sawaya","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.cub.2011.07.040_bib37","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1038\/nature05855","article-title":"Dscam2 mediates axonal tiling in the Drosophila visual system","volume":"447","author":"Millard","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.cub.2011.07.040_bib38","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/j.neuron.2010.08.030","article-title":"Drosophila dscam proteins regulate postsynaptic specificity at multiple-contact synapses","volume":"67","author":"Millard","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2011.07.040_bib39","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/nature06514","article-title":"Neurite arborization and mosaic spacing in the mouse retina require DSCAM","volume":"451","author":"Fuerst","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.cub.2011.07.040_bib40","doi-asserted-by":"crossref","first-page":"2227","DOI":"10.1242\/dev.047795","article-title":"Netrin-guided accessory cell morphogenesis dictates the dendrite orientation and migration of a Drosophila sensory neuron","volume":"137","author":"Mrkusich","year":"2010","journal-title":"Development"}],"container-title":["Current Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960982211008414?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960982211008414?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T09:19:42Z","timestamp":1760779182000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960982211008414"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":40,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["S0960982211008414"],"URL":"https:\/\/doi.org\/10.1016\/j.cub.2011.07.040","relation":{},"ISSN":["0960-9822"],"issn-type":[{"value":"0960-9822","type":"print"}],"subject":[],"published":{"date-parts":[[2011,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dscam1-Mediated Self-Avoidance Counters Netrin-Dependent Targeting of Dendrites in Drosophila","name":"articletitle","label":"Article Title"},{"value":"Current Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cub.2011.07.040","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}