{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T02:30:19Z","timestamp":1791945019648,"version":"4.3.4"},"reference-count":49,"publisher":"Elsevier BV","issue":"20","license":[{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,10,19]],"date-time":"2016-10-19T00:00:00Z","timestamp":1476835200000},"content-version":"vor","delay-in-days":384,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Biology"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1016\/j.cub.2015.08.038","type":"journal-article","created":{"date-parts":[[2015,10,14]],"date-time":"2015-10-14T16:36:54Z","timestamp":1444840614000},"page":"2599-2609","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":208,"title":["A Neural Mechanism for Sensing and Reproducing a Time Interval"],"prefix":"10.1016","volume":"25","author":[{"given":"Mehrdad","family":"Jazayeri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael\u00a0N.","family":"Shadlen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cub.2015.08.038_bib1","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1037\/0033-295X.107.2.289","article-title":"Time, rate, and conditioning","volume":"107","author":"Gallistel","year":"2000","journal-title":"Psychol. Rev."},{"key":"10.1016\/j.cub.2015.08.038_bib2","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1016\/S0028-3932(01)00120-8","article-title":"Orienting attention to instants in time","volume":"39","author":"Nobre","year":"2001","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.cub.2015.08.038_bib3","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1038\/nrn1764","article-title":"What makes us tick? Functional and neural mechanisms of interval timing","volume":"6","author":"Buhusi","year":"2005","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.cub.2015.08.038_bib4","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1146\/annurev.neuro.27.070203.144247","article-title":"The neural basis of temporal processing","volume":"27","author":"Mauk","year":"2004","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.cub.2015.08.038_bib5","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1038\/nn1386","article-title":"A representation of the hazard rate of elapsed time in macaque area LIP","volume":"8","author":"Janssen","year":"2005","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.cub.2015.08.038_bib6","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S0896-6273(03)00185-5","article-title":"Representation of time by neurons in the posterior parietal cortex of the macaque","volume":"38","author":"Leon","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2015.08.038_bib7","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0926-6410(97)00031-1","article-title":"Neuropharmacology of timing and time perception","volume":"6","author":"Meck","year":"1998","journal-title":"Brain Res. Cogn. Brain Res."},{"key":"10.1016\/j.cub.2015.08.038_bib8","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.neuron.2004.12.017","article-title":"The representation of time for motor learning","volume":"45","author":"Medina","year":"2005","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2015.08.038_bib9","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1037\/0735-7044.106.4.666","article-title":"Learning-dependent timing of Pavlovian eyelid responses: differential conditioning using multiple interstimulus intervals","volume":"106","author":"Mauk","year":"1992","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.cub.2015.08.038_bib10","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1038\/nn.2159","article-title":"The temporal precision of reward prediction in dopamine neurons","volume":"11","author":"Fiorillo","year":"2008","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.cub.2015.08.038_bib11","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1038\/nn1617","article-title":"Inactivation of the central thalamus delays self-timed saccades","volume":"9","author":"Tanaka","year":"2006","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.cub.2015.08.038_bib12","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1038\/nn.2272","article-title":"Interval time coding by neurons in the presupplementary and supplementary motor areas","volume":"12","author":"Mita","year":"2009","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.cub.2015.08.038_bib13","doi-asserted-by":"crossref","first-page":"e1001413","DOI":"10.1371\/journal.pbio.1001413","article-title":"Temporal production signals in parietal cortex","volume":"10","author":"Schneider","year":"2012","journal-title":"PLoS Biol."},{"key":"10.1016\/j.cub.2015.08.038_bib14","doi-asserted-by":"crossref","first-page":"19784","DOI":"10.1073\/pnas.1112933108","article-title":"Measuring time with different neural chronometers during a synchronization-continuation task","volume":"108","author":"Merchant","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cub.2015.08.038_bib15","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1038\/nature05078","article-title":"Experience-dependent representation of visual categories in parietal cortex","volume":"443","author":"Freedman","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.cub.2015.08.038_bib16","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1152\/jn.2001.86.4.1916","article-title":"Neural basis of a perceptual decision in the parietal cortex (area LIP) of the rhesus monkey","volume":"86","author":"Shadlen","year":"2001","journal-title":"J.\u00a0Neurophysiol."},{"key":"10.1016\/j.cub.2015.08.038_bib17","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1126\/science.1094765","article-title":"Matching behavior and the representation of value in the parietal cortex","volume":"304","author":"Sugrue","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.cub.2015.08.038_bib18","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/22268","article-title":"Neural correlates of decision variables in parietal cortex","volume":"400","author":"Platt","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.cub.2015.08.038_bib19","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/4594","article-title":"Dissociation of visual, motor and predictive signals in parietal cortex during visual guidance","volume":"2","author":"Eskandar","year":"1999","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.cub.2015.08.038_bib20","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1038\/373518a0","article-title":"Neuronal correlates of inferred motion in primate posterior parietal cortex","volume":"373","author":"Assad","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.cub.2015.08.038_bib21","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1038\/nn1716","article-title":"A cognitive signal for the proactive timing of action in macaque LIP","volume":"9","author":"Maimon","year":"2006","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.cub.2015.08.038_bib22","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1038\/nn.2590","article-title":"Temporal context calibrates interval timing","volume":"13","author":"Jazayeri","year":"2010","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.cub.2015.08.038_bib23","doi-asserted-by":"crossref","first-page":"2528","DOI":"10.1152\/jn.01055.2002","article-title":"Putaminal activity for simple reactions or self-timed movements","volume":"89","author":"Lee","year":"2003","journal-title":"J.\u00a0Neurophysiol."},{"key":"10.1016\/j.cub.2015.08.038_bib24","doi-asserted-by":"crossref","first-page":"9475","DOI":"10.1523\/JNEUROSCI.22-21-09475.2002","article-title":"Response of neurons in the lateral intraparietal area during a combined visual discrimination reaction time task","volume":"22","author":"Roitman","year":"2002","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.cub.2015.08.038_bib25","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1126\/science.274.5286.427","article-title":"Neural control of voluntary movement initiation","volume":"274","author":"Hanes","year":"1996","journal-title":"Science"},{"key":"10.1016\/j.cub.2015.08.038_bib26","doi-asserted-by":"crossref","first-page":"12109","DOI":"10.1523\/JNEUROSCI.1873-07.2007","article-title":"Cognitive signals in the primate motor thalamus predict saccade timing","volume":"27","author":"Tanaka","year":"2007","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.cub.2015.08.038_bib27","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0079-6123(06)55010-1","article-title":"Saccades, salience and attention: the role of the lateral intraparietal area in visual behavior","volume":"155","author":"Goldberg","year":"2006","journal-title":"Prog. Brain Res."},{"key":"10.1016\/j.cub.2015.08.038_bib28","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1038\/35135","article-title":"The representation of visual salience in monkey parietal cortex","volume":"391","author":"Gottlieb","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.cub.2015.08.038_bib29","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1038\/nature01057","article-title":"Attentional modulation in visual cortex depends on task timing","volume":"419","author":"Ghose","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.cub.2015.08.038_bib30","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1146\/annurev.neuro.20.1.303","article-title":"Multimodal representation of space in the posterior parietal cortex and its use in planning movements","volume":"20","author":"Andersen","year":"1997","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.cub.2015.08.038_bib31","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1146\/annurev.neuro.25.112701.142922","article-title":"Intentional maps in posterior parietal cortex","volume":"25","author":"Andersen","year":"2002","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.cub.2015.08.038_bib32","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1146\/annurev.neuro.29.051605.113038","article-title":"The neural basis of decision making","volume":"30","author":"Gold","year":"2007","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.cub.2015.08.038_bib33","doi-asserted-by":"crossref","first-page":"e208","DOI":"10.1371\/journal.pbio.0050208","article-title":"Monotonic coding of numerosity in macaque lateral intraparietal area","volume":"5","author":"Roitman","year":"2007","journal-title":"PLoS Biol."},{"key":"10.1016\/j.cub.2015.08.038_bib34","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1152\/jn.00906.2011","article-title":"Delay activity of saccade-related neurons in the caudal dentate nucleus of the macaque cerebellum","volume":"109","author":"Ashmore","year":"2013","journal-title":"J.\u00a0Neurophysiol."},{"key":"10.1016\/j.cub.2015.08.038_bib35","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1007\/BF00227836","article-title":"Role of primate basal ganglia and frontal cortex in the internal generation of movements. III. Neuronal activity in the supplementary motor area","volume":"91","author":"Romo","year":"1992","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.cub.2015.08.038_bib36","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/BF00227834","article-title":"Role of primate basal ganglia and frontal cortex in the internal generation of movements. I. Preparatory activity in the anterior striatum","volume":"91","author":"Schultz","year":"1992","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.cub.2015.08.038_bib37","doi-asserted-by":"crossref","first-page":"2252","DOI":"10.1152\/jn.01000.2005","article-title":"Transient pauses in delay-period activity of superior colliculus neurons","volume":"95","author":"Li","year":"2006","journal-title":"J.\u00a0Neurophysiol."},{"key":"10.1016\/j.cub.2015.08.038_bib38","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s002210100750","article-title":"Pre-excitatory pause in frontal eye field responses","volume":"139","author":"Sato","year":"2001","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.cub.2015.08.038_bib39","doi-asserted-by":"crossref","first-page":"3287","DOI":"10.1523\/JNEUROSCI.6025-09.2010","article-title":"Temporal sequence of attentional modulation in the lateral intraparietal area and middle temporal area during rapid covert shifts of attention","volume":"30","author":"Herrington","year":"2010","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.cub.2015.08.038_bib40","doi-asserted-by":"crossref","first-page":"12787","DOI":"10.1523\/JNEUROSCI.2327-10.2010","article-title":"Surround suppression sharpens the priority map in the lateral intraparietal area","volume":"30","author":"Falkner","year":"2010","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.cub.2015.08.038_bib41","doi-asserted-by":"crossref","first-page":"14930","DOI":"10.1073\/pnas.1415371111","article-title":"Memory trace and timing mechanism localized to cerebellar Purkinje cells","volume":"111","author":"Johansson","year":"2014","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cub.2015.08.038_bib42","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1073\/pnas.93.2.628","article-title":"Motion perception: seeing and deciding","volume":"93","author":"Shadlen","year":"1996","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cub.2015.08.038_bib43","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.neuron.2004.09.009","article-title":"Activity in posterior parietal cortex is correlated with the relative subjective desirability of action","volume":"44","author":"Dorris","year":"2004","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2015.08.038_bib44","doi-asserted-by":"crossref","first-page":"7457","DOI":"10.1073\/pnas.0402239101","article-title":"A parieto-frontal network for visual numerical information in the monkey","volume":"101","author":"Nieder","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cub.2015.08.038_bib45","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1126\/science.1138071","article-title":"Top-down versus bottom-up control of attention in the prefrontal and posterior parietal cortices","volume":"315","author":"Buschman","year":"2007","journal-title":"Science"},{"key":"10.1016\/j.cub.2015.08.038_bib46","doi-asserted-by":"crossref","first-page":"4869","DOI":"10.1523\/JNEUROSCI.4618-14.2015","article-title":"Reward-based decision signals in parietal cortex are partially embodied","volume":"35","author":"Kubanek","year":"2015","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.cub.2015.08.038_bib47","doi-asserted-by":"crossref","first-page":"6679","DOI":"10.1523\/JNEUROSCI.0499-08.2008","article-title":"Coding of shape and position in macaque lateral intraparietal area","volume":"28","author":"Janssen","year":"2008","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.cub.2015.08.038_bib48","doi-asserted-by":"crossref","first-page":"e88725","DOI":"10.1371\/journal.pone.0088725","article-title":"Neural correlates of temporal credit assignment in the parietal lobe","volume":"9","author":"Gersch","year":"2014","journal-title":"PLoS ONE"},{"key":"10.1016\/j.cub.2015.08.038_bib49","doi-asserted-by":"crossref","first-page":"2254","DOI":"10.1523\/JNEUROSCI.2984-12.2013","article-title":"Signal multiplexing and single-neuron computations in lateral intraparietal area during decision-making","volume":"33","author":"Meister","year":"2013","journal-title":"J.\u00a0Neurosci."}],"container-title":["Current Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S096098221501009X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S096098221501009X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,31]],"date-time":"2019-08-31T15:09:03Z","timestamp":1567264143000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S096098221501009X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":49,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["S096098221501009X"],"URL":"https:\/\/doi.org\/10.1016\/j.cub.2015.08.038","relation":{},"ISSN":["0960-9822"],"issn-type":[{"value":"0960-9822","type":"print"}],"subject":[],"published":{"date-parts":[[2015,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Neural Mechanism for Sensing and Reproducing a Time Interval","name":"articletitle","label":"Article Title"},{"value":"Current Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cub.2015.08.038","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}