{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T06:56:08Z","timestamp":1792652168712,"version":"4.5.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,1,11]],"date-time":"2017-01-11T00:00:00Z","timestamp":1484092800000},"content-version":"vor","delay-in-days":376,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Biology"],"published-print":{"date-parts":[[2016,1]]},"DOI":"10.1016\/j.cub.2015.11.032","type":"journal-article","created":{"date-parts":[[2016,1,11]],"date-time":"2016-01-11T18:30:32Z","timestamp":1452537032000},"page":"R41-R46","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":112,"title":["Genes and Odors Underlying the Recent Evolution of Mosquito Preference for Humans"],"prefix":"10.1016","volume":"26","author":[{"given":"Carolyn\u00a0S.","family":"McBride","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cub.2015.11.032_bib1","series-title":"The Biology of Mosquitoes","author":"Clements","year":"1999"},{"key":"10.1016\/j.cub.2015.11.032_bib2","unstructured":"World Health Organization | Fact sheets. WHO. Available at: http:\/\/www.who.int\/mediacentre\/factsheets\/en\/."},{"key":"10.1016\/j.cub.2015.11.032_bib3","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1080\/00034983.1957.11685829","article-title":"Genetical aspects of the Aedes aegypti problem. I:\u00a0Taxonomy and bionomics","volume":"51","author":"Mattingly","year":"1957","journal-title":"Ann. Trop. Med. Parasitol."},{"key":"10.1016\/j.cub.2015.11.032_bib4","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1146\/annurev-ecolsys-102710-145028","article-title":"Evolution of Anopheles gambiae in relation to humans and malaria","volume":"42","author":"White","year":"2011","journal-title":"Annu. Rev. Ecol. Evol. Syst."},{"key":"10.1016\/j.cub.2015.11.032_bib5","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.ympev.2006.01.006","article-title":"Analysis of the complete mitochondrial DNA from Anopheles funestus: an improved dipteran mitochondrial genome annotation and a temporal dimension of mosquito evolution","volume":"39","author":"Krzywinski","year":"2006","journal-title":"Mol. Phylogenet. Evol."},{"key":"10.1016\/j.cub.2015.11.032_bib6","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.pt.2004.03.007","article-title":"No accounting for taste: host preference in malaria vectors","volume":"20","author":"Besansky","year":"2004","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.cub.2015.11.032_bib7","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1080\/00034983.1963.11686176","article-title":"Serological identification of natural hosts of Aedes aegypti (L.) and some other mosquitoes (Diptera, Culicidae) caught resting in vegetation in Kenya and Uganda","volume":"57","author":"McClelland","year":"1963","journal-title":"Ann. Trop. Med. Parasitol."},{"key":"10.1016\/j.cub.2015.11.032_bib8","unstructured":"McKenna, J. (1973). Attraction of seven strains of Aedes aegypti to man and guinea pig in the laboratory. Ph.D. thesis in Entomology, University of California, Davis."},{"key":"10.1016\/j.cub.2015.11.032_bib9","first-page":"680","article-title":"Host preferences of various strains of Aedes aegypti and Aedes simpsoni as determined by an olfactometer","volume":"47","author":"Gouck","year":"1972","journal-title":"Bull. World Health Org."},{"key":"10.1016\/j.cub.2015.11.032_bib10","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1038\/nature13964","article-title":"Evolution of mosquito preference for humans linked to an odorant receptor","volume":"515","author":"McBride","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.cub.2015.11.032_bib11","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1146\/annurev-ento-120811-153618","article-title":"Host preferences of blood-feeding mosquitoes","volume":"58","author":"Takken","year":"2013","journal-title":"Annu. Rev. Entomol."},{"key":"10.1016\/j.cub.2015.11.032_bib12","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1603\/0022-2585-38.6.868","article-title":"Innate preference for host-odor blends modulates degree of anthropophagy of Anopheles gambiae sensu lato (Diptera: Culicidae)","volume":"38","author":"Dekker","year":"2001","journal-title":"J.\u00a0Med. Entomol."},{"key":"10.1016\/j.cub.2015.11.032_bib13","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1079\/BER200198","article-title":"Differential behaviour of Anopheles gambiae sensu stricto (Diptera: Culicidae) to human and cow odours in the laboratory","volume":"91","author":"Pates","year":"2001","journal-title":"Bull. Entomol. Res."},{"key":"10.1016\/j.cub.2015.11.032_bib14","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1046\/j.1365-2915.1998.00073.x","article-title":"Differential responses of mosquito sibling species Anopheles arabiensis and An. quadriannulatus to carbon dioxide, a man or a calf","volume":"12","author":"Dekker","year":"1998","journal-title":"Med. Vet. Entomol."},{"key":"10.1016\/j.cub.2015.11.032_bib15","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1111\/j.1365-2915.1995.tb00143.x","article-title":"Activation of Anopheles gambiae mosquitoes by carbon dioxide and human breath","volume":"9","author":"Healy","year":"1995","journal-title":"Med. Vet. Entomol."},{"key":"10.1016\/j.cub.2015.11.032_bib16","doi-asserted-by":"crossref","first-page":"2963","DOI":"10.1242\/jeb.01736","article-title":"Carbon dioxide instantly sensitizes female yellow fever mosquitoes to human skin odours","volume":"208","author":"Dekker","year":"2005","journal-title":"J.\u00a0Exp. Biol."},{"key":"10.1016\/j.cub.2015.11.032_bib17","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1007\/BF02765606","article-title":"Odor-mediated flight behavior of Anopheles gambiae Giles sensu stricto and An. stephensi Liston in response to CO2, acetone, and 1-octen-3-ol (Diptera: Culicidae)","volume":"10","author":"Takken","year":"1997","journal-title":"J.\u00a0Insect Behav."},{"key":"10.1016\/j.cub.2015.11.032_bib18","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1111\/phen.12048","article-title":"Close encounters: contributions of carbon dioxide and human skin odour to finding and landing on a host in Aedes aegypti","volume":"39","author":"Lacey","year":"2014","journal-title":"Physiol. Entomol."},{"key":"10.1016\/j.cub.2015.11.032_bib19","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1046\/j.0269-283x.2002.00345.x","article-title":"L-lactic acid: a human-signifying host cue for the anthropophilic mosquito Anopheles gambiae","volume":"16","author":"Dekker","year":"2002","journal-title":"Med. Vet. Entomol."},{"key":"10.1016\/j.cub.2015.11.032_bib20","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1126\/science.161.3848.1346","article-title":"L-Lactic acid: a mosquito attractant isolated from humans","volume":"161","author":"Acree","year":"1968","journal-title":"Science"},{"key":"10.1016\/j.cub.2015.11.032_bib21","series-title":"Olfaction in Mosquito Host Interactions","first-page":"132","article-title":"A search for components in human body odour that attract females of Aedes aegypti","author":"Geier","year":"1996"},{"key":"10.1016\/j.cub.2015.11.032_bib22","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1093\/chemse\/26.5.523","article-title":"The effect of lactic acid on odour-related host preference of yellow fever mosquitoes","volume":"26","author":"Steib","year":"2001","journal-title":"Chem. Sens."},{"key":"10.1016\/j.cub.2015.11.032_bib23","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1046\/j.1365-3032.2001.00227.x","article-title":"The response of the malaria mosquito, Anopheles gambiae, to two components of human sweat, ammonia and l-lactic acid, in an olfactometer","volume":"26","author":"Braks","year":"2001","journal-title":"Physiol. Entomol."},{"key":"10.1016\/j.cub.2015.11.032_bib24","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1093\/chemse\/bji010","article-title":"Synergism between ammonia, lactic acid and carboxylic acids as kairomones in the host-seeking behaviour of the malaria mosquito Anopheles gambiae sensu stricto (Diptera: Culicidae)","volume":"30","author":"Smallegange","year":"2005","journal-title":"Chem. Sens."},{"key":"10.1016\/j.cub.2015.11.032_bib25","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1093\/chemse\/24.6.647","article-title":"Ammonia as an attractive component of host odour for the yellow fever mosquito, Aedes aegypti","volume":"24","author":"Geier","year":"1999","journal-title":"Chem. Sens."},{"key":"10.1016\/j.cub.2015.11.032_bib26","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1093\/oxfordjournals.chemse.a014042","article-title":"Contribution of fatty acids to olfactory host finding of female Aedes aegypti","volume":"25","author":"Bosch","year":"2000","journal-title":"Chem. Sens."},{"key":"10.1016\/j.cub.2015.11.032_bib27","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1603\/0022-2585-40.5.653","article-title":"Synergistic attraction of Aedes aegypti (L.) to binary blends of l-lactic acid and acetone, dichloromethane, or dimethyl disulfide","volume":"40","author":"Bernier","year":"2003","journal-title":"J.\u00a0Med. Entomol."},{"key":"10.1016\/j.cub.2015.11.032_bib28","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1017\/S0007485300027292","article-title":"Behavioural and electrophysiological responses of the female malaria mosquito Anopheles gambiae (Diptera: Culicidae) to Limburger cheese volatiles","volume":"87","author":"Knols","year":"1997","journal-title":"Bull. Entomol. Res."},{"key":"10.1016\/j.cub.2015.11.032_bib29","doi-asserted-by":"crossref","first-page":"288","DOI":"10.2987\/8756-971X(2007)23[288:LCOAAA]2.0.CO;2","article-title":"Laboratory comparison of Aedes aegypti attraction to human odors and to synthetic human odor compounds and blends","volume":"23","author":"Bernier","year":"2007","journal-title":"J.\u00a0Am. Mosquito Control Assoc."},{"key":"10.1016\/j.cub.2015.11.032_bib30","doi-asserted-by":"crossref","first-page":"e8951","DOI":"10.1371\/journal.pone.0008951","article-title":"Development and field evaluation of a synthetic mosquito lure that is more attractive than humans","volume":"5","author":"Okumu","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.cub.2015.11.032_bib31","first-page":"338","article-title":"Effectiveness of synthetic versus natural human volatiles as attractants for Anopheles gambiae (Diptera: Culicidae) sensu stricto","volume":"47","author":"Smallegange","year":"2010","journal-title":"J.\u00a0Med. Entomol."},{"key":"10.1016\/j.cub.2015.11.032_bib32","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.cois.2014.10.006","article-title":"Peripheral olfactory signaling in insects","volume":"6","author":"Suh","year":"2014","journal-title":"Curr. Opin. Insect Sci."},{"key":"10.1016\/j.cub.2015.11.032_bib33","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1038\/nature12206","article-title":"orco mutant mosquitoes lose strong preference for humans and are not repelled by volatile DEET","volume":"498","author":"DeGennaro","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.cub.2015.11.032_bib34","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/s10886-008-9436-0","article-title":"Identification of human-derived volatile chemicals that interfere with attraction of Aedes aegypti mosquitoes","volume":"34","author":"Logan","year":"2008","journal-title":"J.\u00a0Chem. Ecol."},{"key":"10.1016\/j.cub.2015.11.032_bib35","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1186\/1475-2875-9-239","article-title":"Arm-in-cage testing of natural human-derived mosquito repellents","volume":"9","author":"Logan","year":"2010","journal-title":"Malar. J."},{"key":"10.1016\/j.cub.2015.11.032_bib36","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1111\/mve.12061","article-title":"Assessing the efficacy of candidate mosquito repellents against the background of an attractive source that mimics a human host","volume":"28","author":"Menger","year":"2014","journal-title":"Med. Vet. Entomol."},{"key":"10.1016\/j.cub.2015.11.032_bib37","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1111\/j.1365-2583.2007.00748.x","article-title":"Molecular characterization of the Aedes aegypti odorant receptor gene family","volume":"16","author":"Bohbot","year":"2007","journal-title":"Insect Mol. Biol."},{"key":"10.1016\/j.cub.2015.11.032_bib38","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1186\/1471-2164-14-749","article-title":"Antennal transcriptome profiles of anopheline mosquitoes reveal human host olfactory specialization in Anopheles gambiae","volume":"14","author":"Rinker","year":"2013","journal-title":"BMC Genomics"},{"key":"10.1016\/j.cub.2015.11.032_bib39","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/S0022-1910(99)00081-5","article-title":"Olfactory sensitivities of mosquitoes with different host preferences (Anopheles gambiae s.s., An.\u00a0arabiensis, An. quadriannulatus, An. m. atroparvus) to synthetic host odours","volume":"45","author":"van den Broek","year":"1999","journal-title":"J.\u00a0Insect Physiol."},{"key":"10.1016\/j.cub.2015.11.032_bib40","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1038\/nature08834","article-title":"Odorant reception in the malaria mosquito Anopheles gambiae","volume":"464","author":"Carey","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.cub.2015.11.032_bib41","doi-asserted-by":"crossref","first-page":"4418","DOI":"10.1073\/pnas.0913392107","article-title":"Molecular basis of odor coding in the malaria vector mosquito Anopheles gambiae","volume":"107","author":"Wang","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cub.2015.11.032_bib42","doi-asserted-by":"crossref","first-page":"335","DOI":"10.4269\/ajtmh.1970.19.335","article-title":"Blood-feeding habits of four species of mosquito found in Hawaii","volume":"19","author":"Tempelis","year":"1970","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.cub.2015.11.032_bib43","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1093\/jmedent\/11.6.635","article-title":"Host-feeding patterns of mosquitoes, with a review of advances in analysis of blood meals by serology","volume":"11","author":"Tempelis","year":"1975","journal-title":"J.\u00a0Med. Entomol."},{"key":"10.1016\/j.cub.2015.11.032_bib44","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0035-9203(59)90082-3","article-title":"Studies in filariasis in East Africa 1. Filariasis on the island of Pate, Kenya","volume":"53","author":"Heisch","year":"1959","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.cub.2015.11.032_bib45","doi-asserted-by":"crossref","first-page":"3539","DOI":"10.1007\/s00436-015-4634-5","article-title":"Host-feeding pattern of Aedes aegypti and Aedes albopictus (Diptera: Culicidae) in heterogeneous landscapes of South Andaman, Andaman and Nicobar Islands, India","volume":"114","author":"Sivan","year":"2015","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.cub.2015.11.032_bib46","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1093\/jmedent\/42.5.844","article-title":"Blood feeding patterns of Aedes\u00a0aegypti and Aedes albopictus in Thailand","volume":"42","author":"Ponlawat","year":"2005","journal-title":"J.\u00a0Med. Entomol."},{"key":"10.1016\/j.cub.2015.11.032_bib47","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1093\/jmedent\/30.5.922","article-title":"Blood-feeding patterns of Aedes aegypti (Diptera: Culicidae) collected in a rural Thai village","volume":"30","author":"Scott","year":"1993","journal-title":"J.\u00a0Med. Entomol."},{"key":"10.1016\/j.cub.2015.11.032_bib48","first-page":"711","article-title":"Studies on the bionomics of Aedes aegypti (L.) in its natural habitats in a coastal region of Kenya","volume":"56","author":"Teesdale","year":"1956","journal-title":"Bull. Entomol. Res."},{"key":"10.1016\/j.cub.2015.11.032_bib49","series-title":"Olfaction in Vector-Host Interactions","first-page":"39","article-title":"Olfactory physiology of blood-feeding vector mosquitoes","author":"Qiu","year":"2010"},{"key":"10.1016\/j.cub.2015.11.032_bib50","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1007\/s10886-009-9668-7","article-title":"The effect of aliphatic carboxylic acids on olfaction-based host-seeking of the malaria mosquito Anopheles gambiae sensu stricto","volume":"35","author":"Smallegange","year":"2009","journal-title":"J.\u00a0Chem. Ecol."}],"container-title":["Current Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960982215014268?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960982215014268?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T18:56:31Z","timestamp":1718304991000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960982215014268"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["S0960982215014268"],"URL":"https:\/\/doi.org\/10.1016\/j.cub.2015.11.032","relation":{},"ISSN":["0960-9822"],"issn-type":[{"value":"0960-9822","type":"print"}],"subject":[],"published":{"date-parts":[[2016,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Genes and Odors Underlying the Recent Evolution of Mosquito Preference for Humans","name":"articletitle","label":"Article Title"},{"value":"Current Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cub.2015.11.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}