{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T18:30:15Z","timestamp":1789756215117,"version":"4.0.1"},"reference-count":60,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,2,8]],"date-time":"2022-02-08T00:00:00Z","timestamp":1644278400000},"content-version":"vor","delay-in-days":372,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100005492","name":"Stanford University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005492","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008069","name":"University of California, San Francisco","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008069","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Biology"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.cub.2020.11.035","type":"journal-article","created":{"date-parts":[[2020,11,25]],"date-time":"2020-11-25T10:35:57Z","timestamp":1606300557000},"page":"601-612.e3","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"title":["Human Responses to Visually Evoked Threat"],"prefix":"10.1016","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2343-8895","authenticated-orcid":false,"given":"Melis","family":"Yilmaz Balban","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5389-5886","authenticated-orcid":false,"given":"Erin","family":"Cafaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1027-2571","authenticated-orcid":false,"given":"Lauren","family":"Saue-Fletcher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1035-9530","authenticated-orcid":false,"given":"Marlon J.","family":"Washington","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9060-8129","authenticated-orcid":false,"given":"Maryam","family":"Bijanzadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. Moses","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2480-4700","authenticated-orcid":false,"given":"Edward F.","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew D.","family":"Huberman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cub.2020.11.035_bib1","doi-asserted-by":"crossref","first-page":"17024","DOI":"10.1038\/nrdp.2017.24","article-title":"Anxiety disorders","volume":"3","author":"Craske","year":"2017","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.cub.2020.11.035_bib2","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/j.nicl.2016.09.023","article-title":"Specifically altered brain responses to threat in generalized anxiety disorder relative to social anxiety disorder and panic disorder","volume":"12","author":"Buff","year":"2016","journal-title":"Neuroimage Clin."},{"key":"10.1016\/j.cub.2020.11.035_bib3","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1017\/S0033291716002634","article-title":"Transdiagnostic brain responses to disorder-related threat across four psychiatric disorders","volume":"47","author":"Feldker","year":"2017","journal-title":"Psychol. Med."},{"key":"10.1016\/j.cub.2020.11.035_bib4","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.1016\/j.cub.2013.08.015","article-title":"Rapid innate defensive responses of mice to looming visual stimuli","volume":"23","author":"Yilmaz","year":"2013","journal-title":"Curr. Biol."},{"key":"10.1016\/j.cub.2020.11.035_bib5","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/s41586-018-0078-2","article-title":"A midline thalamic circuit determines reactions to visual threat","volume":"557","author":"Salay","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.cub.2020.11.035_bib6","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/j.cub.2018.02.005","article-title":"Stress accelerates defensive responses to looming in mice and involves a locus coeruleus-superior colliculus projection","volume":"28","author":"Li","year":"2018","journal-title":"Curr. Biol."},{"key":"10.1016\/j.cub.2020.11.035_bib7","doi-asserted-by":"crossref","first-page":"37","DOI":"10.3389\/fpsyt.2014.00037","article-title":"Posttraumatic stress disorder: a theoretical model of the hyperarousal subtype","volume":"5","author":"Weston","year":"2014","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.cub.2020.11.035_bib8","doi-asserted-by":"crossref","first-page":"193","DOI":"10.2147\/NSS.S138823","article-title":"Hyperarousal and sleep reactivity in insomnia: current insights","volume":"10","author":"Kalmbach","year":"2018","journal-title":"Nat. Sci. Sleep"},{"key":"10.1016\/j.cub.2020.11.035_bib9","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1001\/jamapsychiatry.2017.3951","article-title":"Transdiagnostic symptom clusters and associations with brain, behavior, and daily function in mood, anxiety, and trauma disorders","volume":"75","author":"Grisanzio","year":"2018","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.cub.2020.11.035_bib10","doi-asserted-by":"crossref","first-page":"2150","DOI":"10.1016\/j.cub.2016.06.006","article-title":"Vision guides selection of freeze or flight defense strategies in mice","volume":"26","author":"De Franceschi","year":"2016","journal-title":"Curr. Biol."},{"key":"10.1016\/j.cub.2020.11.035_bib11","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.cobeha.2018.02.007","article-title":"Fear paradigms: the times they are a-changin\u2019","volume":"24","author":"Kim","year":"2018","journal-title":"Curr. Opin. Behav. Sci."},{"key":"10.1016\/j.cub.2020.11.035_bib12","doi-asserted-by":"crossref","first-page":"3186","DOI":"10.1073\/pnas.1712314115","article-title":"How cognitive and reactive fear circuits optimize escape decisions in humans","volume":"115","author":"Qi","year":"2018","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cub.2020.11.035_bib13","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1126\/science.1144298","article-title":"When fear is near: threat imminence elicits prefrontal-periaqueductal gray shifts in humans","volume":"317","author":"Mobbs","year":"2007","journal-title":"Science"},{"key":"10.1016\/j.cub.2020.11.035_bib14","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.conb.2008.06.006","article-title":"Fear, faces, and the human amygdala","volume":"18","author":"Adolphs","year":"2008","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.cub.2020.11.035_bib15","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.physbeh.2007.05.057","article-title":"On the unconscious subcortical origin of human fear","volume":"92","author":"\u00d6hman","year":"2007","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.cub.2020.11.035_bib16","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/S0149-7634(01)00056-2","article-title":"Human defensive behaviors to threat scenarios show parallels to fear- and anxiety-related defense patterns of non-human mammals","volume":"25","author":"Blanchard","year":"2001","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.cub.2020.11.035_bib17","doi-asserted-by":"crossref","first-page":"e0133682","DOI":"10.1371\/journal.pone.0133682","article-title":"Exploring the structure of human defensive responses from judgments of threat scenarios","volume":"10","author":"Harrison","year":"2015","journal-title":"PLoS ONE"},{"key":"10.1016\/j.cub.2020.11.035_bib18","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.cub.2014.01.046","article-title":"Human hippocampus arbitrates approach-avoidance conflict","volume":"24","author":"Bach","year":"2014","journal-title":"Curr. Biol."},{"key":"10.1016\/j.cub.2020.11.035_bib19","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.tics.2016.11.001","article-title":"Differences in behavior and brain activity during hypothetical and real choices","volume":"21","author":"Camerer","year":"2017","journal-title":"Trends Cogn. Sci."},{"key":"10.1016\/j.cub.2020.11.035_bib20","doi-asserted-by":"crossref","first-page":"3743","DOI":"10.1016\/j.cub.2017.10.062","article-title":"Theta oscillations in the human medial temporal lobe during real-world ambulatory movement","volume":"27","author":"M Aghajan","year":"2017","journal-title":"Curr. Biol."},{"key":"10.1016\/j.cub.2020.11.035_bib21","doi-asserted-by":"crossref","first-page":"408","DOI":"10.3389\/fnins.2018.00408","article-title":"Enhancing the ecological validity of fMRI memory research using virtual reality","volume":"12","author":"Reggente","year":"2018","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.cub.2020.11.035_bib22","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1207\/S15327965PLI1302_01","article-title":"Immersive virtual environment technology as a methodological tool for social psychology","volume":"13","author":"Blascovich","year":"2002","journal-title":"Psychol. Inq."},{"key":"10.1016\/j.cub.2020.11.035_bib23","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1080\/15213269.2015.1015740","article-title":"How immersive is enough? A meta-analysis of the effect of immersive technology on user presence","volume":"19","author":"Cummings","year":"2016","journal-title":"Media Psychol."},{"issue":"sup5","key":"10.1016\/j.cub.2020.11.035_bib24","doi-asserted-by":"crossref","first-page":"1414560","DOI":"10.1080\/20008198.2017.1414560","article-title":"Clinical virtual reality tools to advance the prevention, assessment, and treatment of PTSD","volume":"8","author":"Rizzo","year":"2017","journal-title":"Eur. J. Psychotraumatol."},{"key":"10.1016\/j.cub.2020.11.035_bib25","doi-asserted-by":"crossref","first-page":"e48469","DOI":"10.1371\/journal.pone.0048469","article-title":"Efficacy of virtual reality exposure therapy in the treatment of PTSD: a systematic review","volume":"7","author":"Gon\u00e7alves","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.cub.2020.11.035_bib26","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.janxdis.2018.08.003","article-title":"Virtual reality exposure therapy for anxiety and related disorders: a meta-analysis of randomized controlled trials","volume":"61","author":"Carl","year":"2019","journal-title":"J.\u00a0Anxiety Disord."},{"key":"10.1016\/j.cub.2020.11.035_bib27","series-title":"Animal Models in Psychopharmacology","first-page":"117","article-title":"Risk assessment and animal models of anxiety","author":"Blanchard","year":"1991"},{"key":"10.1016\/j.cub.2020.11.035_bib28","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1016\/j.neubiorev.2010.10.016","article-title":"Risk assessment as an evolved threat detection and analysis process","volume":"35","author":"Blanchard","year":"2011","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.cub.2020.11.035_bib29","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1037\/h0062283","article-title":"Some quantitative properties of anxiety","volume":"29","author":"Estes","year":"1941","journal-title":"J.\u00a0Exp. Psychol."},{"key":"10.1016\/j.cub.2020.11.035_bib30","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.beproc.2015.06.011","article-title":"Frozen with fear: conditioned suppression in a virtual reality model of human anxiety","volume":"118","author":"Allcoat","year":"2015","journal-title":"Behav. Processes"},{"key":"10.1016\/j.cub.2020.11.035_bib31","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.chb.2012.11.016","article-title":"Conditioned suppression in a virtual environment","volume":"29","author":"Greville","year":"2013","journal-title":"Comput. Human Behav."},{"key":"10.1016\/j.cub.2020.11.035_bib32","doi-asserted-by":"crossref","first-page":"16146","DOI":"10.1038\/s41598-018-34289-8","article-title":"The effect of anxiety on emotional recognition: evidence from an ERP study","volume":"8","author":"Yu","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cub.2020.11.035_bib33","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/nn1176","article-title":"Neural systems supporting interoceptive awareness","volume":"7","author":"Critchley","year":"2004","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.cub.2020.11.035_bib34","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1038\/s41593-019-0469-1","article-title":"Aversive state processing in the posterior insular cortex","volume":"22","author":"Gehrlach","year":"2019","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.cub.2020.11.035_bib35","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1093\/cercor\/10.3.295","article-title":"Emotion, decision making and the orbitofrontal cortex","volume":"10","author":"Bechara","year":"2000","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.cub.2020.11.035_bib36","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1038\/nn.3982","article-title":"What the orbitofrontal cortex does not do","volume":"18","author":"Stalnaker","year":"2015","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.cub.2020.11.035_bib37","doi-asserted-by":"crossref","first-page":"R1083","DOI":"10.1016\/j.cub.2018.07.018","article-title":"Orbitofrontal cortex","volume":"28","author":"Rudebeck","year":"2018","journal-title":"Curr. Biol."},{"key":"10.1016\/j.cub.2020.11.035_bib38","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/j.1749-6632.2001.tb03476.x","article-title":"The anterior cingulate cortex. The evolution of an interface between emotion and cognition","volume":"935","author":"Allman","year":"2001","journal-title":"Ann. N Y Acad. Sci."},{"key":"10.1016\/j.cub.2020.11.035_bib39","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.neuron.2009.12.002","article-title":"Synchronized activity between the ventral hippocampus and the medial prefrontal cortex during anxiety","volume":"65","author":"Adhikari","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2020.11.035_bib40","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1016\/j.cell.2018.10.005","article-title":"An amygdala-hippocampus subnetwork that encodes variation in human mood","volume":"175","author":"Kirkby","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.cub.2020.11.035_bib41","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1097\/WNP.0000000000000377","article-title":"Structure and function of the human insula","volume":"34","author":"Uddin","year":"2017","journal-title":"J.\u00a0Clin. Neurophysiol."},{"key":"10.1016\/j.cub.2020.11.035_bib42","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.tins.2017.02.002","article-title":"The insula: an underestimated brain area in clinical neuroscience, psychiatry, and neurology","volume":"40","author":"Namkung","year":"2017","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.cub.2020.11.035_bib43","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1093\/cercor\/bhx334","article-title":"The roles of subdivisions of human insula in emotion perception and auditory processing","volume":"29","author":"Zhang","year":"2019","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.cub.2020.11.035_bib44","doi-asserted-by":"crossref","first-page":"e105906","DOI":"10.1371\/journal.pone.0105906","article-title":"Visual exploration during locomotion limited by fear of heights","volume":"9","author":"Kugler","year":"2014","journal-title":"PLoS ONE"},{"key":"10.1016\/j.cub.2020.11.035_bib45","doi-asserted-by":"crossref","first-page":"433","DOI":"10.3233\/VES-140529","article-title":"Fear of heights freezes gaze to the horizon","volume":"24","author":"Kugler","year":"2014","journal-title":"J.\u00a0Vestib. Res."},{"key":"10.1016\/j.cub.2020.11.035_bib46","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1089\/cyber.2015.0326","article-title":"Identifying anxiety through tracked head movements in a virtual classroom","volume":"19","author":"Won","year":"2016","journal-title":"Cyberpsychol. Behav. Soc. Netw."},{"key":"10.1016\/j.cub.2020.11.035_bib47","doi-asserted-by":"crossref","first-page":"2116","DOI":"10.3389\/fpsyg.2017.02116","article-title":"A public database of immersive VR videos with corresponding ratings of arousal, valence, and correlations between head movements and self report measures","volume":"8","author":"Li","year":"2017","journal-title":"Front. Psychol."},{"issue":"Suppl","key":"10.1016\/j.cub.2020.11.035_bib48","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/0278-5846(89)90105-X","article-title":"Attack and defense in rodents as ethoexperimental models for the study of emotion","volume":"13","author":"Blanchard","year":"1989","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.cub.2020.11.035_bib49","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.neubiorev.2014.02.014","article-title":"Brain systems underlying the affective and social monitoring of actions: an integrative review","volume":"46","author":"Koban","year":"2014","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.cub.2020.11.035_bib50","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1006\/nimg.2002.1087","article-title":"Functional neuroanatomy of emotion: a meta-analysis of emotion activation studies in PET and fMRI","volume":"16","author":"Phan","year":"2002","journal-title":"Neuroimage"},{"key":"10.1016\/j.cub.2020.11.035_bib51","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1176\/appi.ajp.2007.07030504","article-title":"Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia","volume":"164","author":"Etkin","year":"2007","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.cub.2020.11.035_bib52","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.jad.2019.05.046","article-title":"Social anxiety, posterior insula activation, and autonomic response during self-initiated action in a Cyberball game","volume":"255","author":"Wang","year":"2019","journal-title":"J.\u00a0Affect. Disord."},{"key":"10.1016\/j.cub.2020.11.035_bib53","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/nrn2555","article-title":"How do you feel\u2013now? The anterior insula and human awareness","volume":"10","author":"Craig","year":"2009","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.cub.2020.11.035_bib54","doi-asserted-by":"crossref","first-page":"8596","DOI":"10.1038\/s41598-018-26995-0","article-title":"Subcortical structural connectivity of insular subregions","volume":"8","author":"Ghaziri","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cub.2020.11.035_bib55","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1073\/pnas.1712214114","article-title":"Closing the loop on impulsivity via nucleus accumbens delta-band activity in mice and man","volume":"115","author":"Wu","year":"2018","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cub.2020.11.035_bib56","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/nature11020","article-title":"Selective cortical representation of attended speaker in multi-talker speech perception","volume":"485","author":"Mesgarani","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.cub.2020.11.035_bib57","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.neuroimage.2012.01.021","article-title":"FreeSurfer","volume":"62","author":"Fischl","year":"2012","journal-title":"Neuroimage"},{"key":"10.1016\/j.cub.2020.11.035_bib58","first-page":"797","article-title":"cvxEDA: a convex optimization approach to electrodermal activity processing","volume":"63","author":"Greco","year":"2016","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"10.1016\/j.cub.2020.11.035_bib59","doi-asserted-by":"crossref","first-page":"3893","DOI":"10.1016\/j.cub.2018.10.026","article-title":"Direct electrical stimulation of lateral orbitofrontal cortex acutely improves mood in individuals with symptoms of depression","volume":"28","author":"Rao","year":"2018","journal-title":"Curr. Biol."},{"key":"10.1016\/j.cub.2020.11.035_bib60","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1006\/nimg.1997.0290","article-title":"Multimodal image coregistration and partitioning--a unified framework","volume":"6","author":"Ashburner","year":"1997","journal-title":"Neuroimage"}],"container-title":["Current Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960982220317462?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960982220317462?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T09:50:43Z","timestamp":1760781043000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960982220317462"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":60,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["S0960982220317462"],"URL":"https:\/\/doi.org\/10.1016\/j.cub.2020.11.035","relation":{},"ISSN":["0960-9822"],"issn-type":[{"value":"0960-9822","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Human Responses to Visually Evoked Threat","name":"articletitle","label":"Article Title"},{"value":"Current Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cub.2020.11.035","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}