{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T00:14:19Z","timestamp":1769818459025,"version":"3.49.0"},"reference-count":88,"publisher":"Elsevier BV","issue":"15","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T00:00:00Z","timestamp":1750377600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004826","name":"Beijing Natural Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","award":["2022ZD0207500"],"award-info":[{"award-number":["2022ZD0207500"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019018","name":"Chinese Academy of Medical Sciences Initiative for Innovative Medicine","doi-asserted-by":"publisher","award":["2024-I2M-ZD-013"],"award-info":[{"award-number":["2024-I2M-ZD-013"]}],"id":[{"id":"10.13039\/501100019018","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005150","name":"Chinese Academy of Medical Sciences & Peking Union Medical College","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005150","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005089","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["5254052"],"award-info":[{"award-number":["5254052"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Biology"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.cub.2025.06.050","type":"journal-article","created":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T17:18:44Z","timestamp":1752599924000},"page":"3650-3663.e6","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Altered cortical dynamics and adaptive behavior following early-onset sucrose overconsumption"],"prefix":"10.1016","volume":"35","author":[{"given":"Huixin","family":"Lin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingjun","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhaoyang","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingchun","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1893-1025","authenticated-orcid":false,"given":"Jingfeng","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cub.2025.06.050_bib1","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0002-8223(00)00018-3","article-title":"Food sources of added sweeteners in the diets of Americans","volume":"100","author":"Guthrie","year":"2000","journal-title":"J. Am. Diet. Assoc."},{"key":"10.1016\/j.cub.2025.06.050_bib2","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1161\/CIRCULATIONAHA.109.192627","article-title":"Dietary sugars intake and cardiovascular health: a scientific statement from the American Heart Association","volume":"120","author":"Johnson","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.cub.2025.06.050_bib3","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.e7492","article-title":"Dietary sugars and body weight: systematic review and meta-analyses of randomised controlled trials and cohort studies","volume":"346","author":"Te Morenga","year":"2012","journal-title":"BMJ"},{"key":"10.1016\/j.cub.2025.06.050_bib4","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-023-41269-8","article-title":"Sugar-sweetened beverage intakes among adults between 1990 and 2018 in 185 countries","volume":"14","author":"Lara-Castor","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.cub.2025.06.050_bib5","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/482027a","article-title":"The toxic truth about sugar","volume":"482","author":"Lustig","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.cub.2025.06.050_bib6","doi-asserted-by":"crossref","first-page":"e1017","DOI":"10.1161\/CIR.0000000000000439","article-title":"Added sugars and cardiovascular disease risk in children: a scientific statement from the American Heart Association","volume":"135","author":"Vos","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.cub.2025.06.050_bib7","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/S1054-139X(03)00248-9","article-title":"Children and adolescents\u2019 choices of foods and beverages high in added sugars are associated with intakes of key nutrients and food groups","volume":"34","author":"Frary","year":"2004","journal-title":"J. Adolesc. Health"},{"key":"10.1016\/j.cub.2025.06.050_bib8","doi-asserted-by":"crossref","first-page":"2156","DOI":"10.1038\/s41366-021-00894-3","article-title":"Learning of food preferences: mechanisms and implications for obesity & metabolic diseases","volume":"45","author":"Berthoud","year":"2021","journal-title":"Int. J. Obes. (Lond)"},{"key":"10.1016\/j.cub.2025.06.050_bib9","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1038\/s41574-021-00627-6","article-title":"The role of sugar-sweetened beverages in the global epidemics of obesity and chronic diseases","volume":"18","author":"Malik","year":"2022","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.cub.2025.06.050_bib10","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2021.670430","article-title":"Long-term overconsumption of sugar starting at adolescence produces persistent hyperactivity and neurocognitive deficits in adulthood","volume":"15","author":"Beecher","year":"2021","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.cub.2025.06.050_bib11","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0009296","article-title":"Sugar overconsumption during adolescence selectively alters motivation and reward function in adult rats","volume":"5","author":"Vendruscolo","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.cub.2025.06.050_bib12","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.neuropharm.2017.11.021","article-title":"Protracted motivational dopamine-related deficits following adolescence sugar overconsumption","volume":"129","author":"Naneix","year":"2018","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.cub.2025.06.050_bib13","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1080\/1028415X.2017.1378851","article-title":"Early-life sugar consumption has long-term negative effects on memory function in male rats","volume":"22","author":"Noble","year":"2019","journal-title":"Nutr. Neurosci."},{"key":"10.1016\/j.cub.2025.06.050_bib14","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.neuroscience.2015.12.018","article-title":"High sucrose consumption induces memory impairment in rats associated with electrophysiological modifications but not with metabolic changes in the hippocampus","volume":"315","author":"Lemos","year":"2016","journal-title":"Neuroscience"},{"key":"10.1016\/j.cub.2025.06.050_bib15","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.physbeh.2013.08.012","article-title":"Chronic restricted access to 10% sucrose solution in adolescent and young adult rats impairs spatial memory and alters sensitivity to outcome devaluation","volume":"120","author":"Kendig","year":"2013","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.cub.2025.06.050_bib16","article-title":"Long-term consumption of sugar-sweetened beverage during the growth period promotes social aggression in adult mice with proinflammatory responses in the brain","volume":"7","author":"Choi","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cub.2025.06.050_bib17","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1039\/C8FO02118J","article-title":"A high-fat high-sugar diet in adolescent rats impairs social memory and alters chemical markers characteristic of atypical neuroplasticity and parvalbumin interneuron depletion in the medial prefrontal cortex","volume":"10","author":"Reichelt","year":"2019","journal-title":"Food Funct."},{"key":"10.1016\/j.cub.2025.06.050_bib18","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.neubiorev.2007.04.019","article-title":"Evidence for sugar addiction: Behavioral and neurochemical effects of intermittent, excessive sugar intake","volume":"32","author":"Avena","year":"2008","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.cub.2025.06.050_bib19","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1136\/bjsports-2017-097971","article-title":"Sugar addiction: is it real? A narrative review","volume":"52","author":"DiNicolantonio","year":"2018","journal-title":"Br. J. Sports Med."},{"key":"10.1016\/j.cub.2025.06.050_bib20","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2018.00545","article-title":"Sugar addiction: from evolution to revolution","volume":"9","author":"Wiss","year":"2018","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.cub.2025.06.050_bib21","doi-asserted-by":"crossref","first-page":"2627","DOI":"10.1038\/s41386-018-0025-9","article-title":"Unlimited sucrose consumption during adolescence generates a depressive-like phenotype in adulthood","volume":"43","author":"Gueye","year":"2018","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.cub.2025.06.050_bib22","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1111\/ejn.13149","article-title":"Long-lasting deficits in hedonic and nucleus accumbens reactivity to sweet rewards by sugar overconsumption during adolescence","volume":"43","author":"Naneix","year":"2016","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.cub.2025.06.050_bib23","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1007\/s13668-019-0270-5","article-title":"Excessive consumption of sugar: an insatiable drive for reward","volume":"8","author":"Olszewski","year":"2019","journal-title":"Curr. Nutr. Rep."},{"key":"10.1016\/j.cub.2025.06.050_bib24","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.neubiorev.2019.05.021","article-title":"The impact of sugar consumption on stress driven, emotional and addictive behaviors","volume":"103","author":"Jacques","year":"2019","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.cub.2025.06.050_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.mehy.2019.109421","article-title":"The depressogenic potential of added dietary sugars","volume":"134","author":"Reis","year":"2020","journal-title":"Med. Hypotheses"},{"key":"10.1016\/j.cub.2025.06.050_bib26","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.neuroscience.2024.09.028","article-title":"Intermittent access to sugary drinks associated with fasting induces overeating and depressive-like behavior in female C57BL\/6J mice","volume":"560","author":"Paim","year":"2024","journal-title":"Neuroscience"},{"key":"10.1016\/j.cub.2025.06.050_bib27","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.physbeh.2018.06.027","article-title":"Binge-like intake of sucrose reduces the rewarding value of sucrose in adult rats","volume":"194","author":"Smail-Crevier","year":"2018","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.cub.2025.06.050_bib28","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.neuropharm.2017.11.041","article-title":"Sucrose withdrawal induces depression and anxiety-like behavior by Kir2.1 upregulation in the nucleus accumbens","volume":"130","author":"Kim","year":"2018","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.cub.2025.06.050_bib29","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.molbrainres.2004.02.013","article-title":"Opiate-like effects of sugar on gene expression in reward areas of the rat brain","volume":"124","author":"Spangler","year":"2004","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.cub.2025.06.050_bib30","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.brainres.2005.05.012","article-title":"Chronic sucrose ingestion enhances mu-opioid discriminative stimulus effects","volume":"1050","author":"Jewett","year":"2005","journal-title":"Brain Res."},{"key":"10.1016\/j.cub.2025.06.050_bib31","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1097\/00001756-200208270-00017","article-title":"Repeated sucrose access influences dopamine D2 receptor density in the striatum","volume":"13","author":"Bello","year":"2002","journal-title":"NeuroReport"},{"key":"10.1016\/j.cub.2025.06.050_bib32","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2016.00054","article-title":"Prolonged consumption of sucrose in a binge-like manner, alters the morphology of medium spiny neurons in the nucleus accumbens shell","volume":"10","author":"Klenowski","year":"2016","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.cub.2025.06.050_bib33","doi-asserted-by":"crossref","first-page":"3549","DOI":"10.1097\/00001756-200111160-00035","article-title":"Excessive sugar intake alters binding to dopamine and mu-opioid receptors in the brain","volume":"12","author":"Colantuoni","year":"2001","journal-title":"NeuroReport"},{"key":"10.1016\/j.cub.2025.06.050_bib34","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1038\/oby.2002.66","article-title":"Evidence that intermittent, excessive sugar intake causes endogenous opioid dependence","volume":"10","author":"Colantuoni","year":"2002","journal-title":"Obes. Res."},{"key":"10.1016\/j.cub.2025.06.050_bib35","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/j.neuroscience.2005.12.037","article-title":"Sucrose sham feeding on a binge schedule releases accumbens dopamine repeatedly and eliminates the acetylcholine satiety response","volume":"139","author":"Avena","year":"2006","journal-title":"Neuroscience"},{"key":"10.1016\/j.cub.2025.06.050_bib36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1196\/annals.1390.008","article-title":"Learning about multiple attributes of reward in Pavlovian conditioning","volume":"1104","author":"Delamater","year":"2007","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.cub.2025.06.050_bib37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3758\/s13420-011-0036-4","article-title":"On the nature of CS and US representations in Pavlovian learning","volume":"40","author":"Delamater","year":"2012","journal-title":"Learn. Behav."},{"key":"10.1016\/j.cub.2025.06.050_bib38","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1037\/bne0000455","article-title":"To be specific: The role of orbitofrontal cortex in signaling reward identity","volume":"135","author":"Howard","year":"2021","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.cub.2025.06.050_bib39","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1523\/JNEUROSCI.4507-04.2005","article-title":"Double dissociation of basolateral and central amygdala lesions on the general and outcome-specific forms of pavlovian-instrumental transfer","volume":"25","author":"Corbit","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cub.2025.06.050_bib40","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S0028-3908(98)00033-1","article-title":"Goal-directed instrumental action: contingency and incentive learning and their cortical substrates","volume":"37","author":"Balleine","year":"1998","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.cub.2025.06.050_bib41","doi-asserted-by":"crossref","first-page":"4819","DOI":"10.1523\/JNEUROSCI.5443-06.2007","article-title":"Orbitofrontal cortex mediates outcome encoding in Pavlovian but Not instrumental conditioning","volume":"27","author":"Ostlund","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cub.2025.06.050_bib42","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1523\/JNEUROSCI.3758-08.2009","article-title":"The basolateral amygdala is critical to the expression of Pavlovian and instrumental outcome-specific reinforcer devaluation effects","volume":"29","author":"Johnson","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cub.2025.06.050_bib43","article-title":"The origins and organization of vertebrate Pavlovian conditioning","volume":"8","author":"Fanselow","year":"2015","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.cub.2025.06.050_bib44","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.68617","article-title":"A bidirectional corticoamygdala circuit for the encoding and retrieval of detailed reward memories","volume":"10","author":"Sias","year":"2021","journal-title":"eLife"},{"key":"10.1016\/j.cub.2025.06.050_bib45","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.adn4203","article-title":"Mesostriatal dopamine is sensitive to changes in specific cue-reward contingencies","volume":"10","author":"Garr","year":"2024","journal-title":"Sci. Adv."},{"key":"10.1016\/j.cub.2025.06.050_bib46","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1038\/s41583-024-00898-8","article-title":"The curious case of dopaminergic prediction errors and learning associative information beyond value","volume":"26","author":"Kahnt","year":"2025","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.cub.2025.06.050_bib47","first-page":"2553","article-title":"Reconciling the influence of predictiveness and uncertainty on stimulus salience: a model of attention in associative learning","volume":"278","author":"Esber","year":"2011","journal-title":"Proc. Biol. Sci."},{"key":"10.1016\/j.cub.2025.06.050_bib48","article-title":"Associative learning through acquired salience","volume":"9","author":"Trevi\u00f1o","year":"2015","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.cub.2025.06.050_bib49","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.neuron.2013.10.020","article-title":"Flow of cortical activity underlying a tactile decision in mice","volume":"81","author":"Guo","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2025.06.050_bib50","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/s41586-019-1787-x","article-title":"Distributed coding of choice, action and engagement across the mouse brain","volume":"576","author":"Steinmetz","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.cub.2025.06.050_bib51","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1126\/science.1123513","article-title":"Reward timing in the primary visual cortex","volume":"311","author":"Shuler","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.cub.2025.06.050_bib52","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.neuron.2018.03.045","article-title":"The neural basis of timing: distributed mechanisms for diverse functions","volume":"98","author":"Paton","year":"2018","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2025.06.050_bib53","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.neuron.2017.04.015","article-title":"Transformation of cortex-wide emergent properties during motor learning","volume":"94","author":"Makino","year":"2017","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2025.06.050_bib54","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.neuron.2007.10.007","article-title":"Spatiotemporal dynamics of cortical sensorimotor integration in behaving mice","volume":"56","author":"Ferezou","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2025.06.050_bib55","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1016\/j.cub.2024.02.004","article-title":"Differences in the expression of cortex-wide neural dynamics are related to behavioral phenotype","volume":"34","author":"MacDowell","year":"2024","journal-title":"Curr. Biol."},{"key":"10.1016\/j.cub.2025.06.050_bib56","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1038\/s41593-019-0502-4","article-title":"Single-trial neural dynamics are dominated by richly varied movements","volume":"22","author":"Musall","year":"2019","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.cub.2025.06.050_bib57","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/j.neuron.2019.08.025","article-title":"Task-dependent changes in the large-scale dynamics and necessity of cortical regions","volume":"104","author":"Pinto","year":"2019","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2025.06.050_bib58","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.neuron.2018.09.050","article-title":"Imaging cortical dynamics in GCaMP transgenic rats with a head-mounted widefield macroscope","volume":"100","author":"Scott","year":"2018","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2025.06.050_bib59","doi-asserted-by":"crossref","first-page":"2668","DOI":"10.1093\/cercor\/bhab373","article-title":"Wide-field calcium imaging of dynamic cortical networks during locomotion","volume":"32","author":"West","year":"2022","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.cub.2025.06.050_bib60","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1038\/s41586-022-04478-7","article-title":"Cortical processing of flexible and context-dependent sensorimotor sequences","volume":"603","author":"Xu","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.cub.2025.06.050_bib61","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.neuroscience.2005.04.043","article-title":"Daily bingeing on sugar repeatedly releases dopamine in the accumbens shell","volume":"134","author":"Rada","year":"2005","journal-title":"Neuroscience"},{"key":"10.1016\/j.cub.2025.06.050_bib62","first-page":"224","article-title":"High sucrose consumption decouples intrinsic and synaptic excitability of AgRP neurons without altering body weight","volume":"47","author":"Korgan","year":"2023","journal-title":"Int. J. Obes. (Lond)"},{"key":"10.1016\/j.cub.2025.06.050_bib63","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1109\/MSP.2014.2300511","article-title":"Diversity in independent component and vector analyses: identifiability, algorithms, and applications in medical imaging","volume":"31","author":"Adali","year":"2014","journal-title":"IEEE Signal Process. Mag."},{"key":"10.1016\/j.cub.2025.06.050_bib64","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.neuroimage.2006.08.031","article-title":"Independent component analysis of high-resolution imaging data identifies distinct functional domains","volume":"34","author":"Reidl","year":"2007","journal-title":"NeuroImage"},{"key":"10.1016\/j.cub.2025.06.050_bib65","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1002\/hbm.1048","article-title":"A method for making group inferences from functional MRI data using independent component analysis","volume":"14","author":"Calhoun","year":"2001","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.cub.2025.06.050_bib66","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1002\/jmri.28439","article-title":"Independent component and graph theory analyses reveal normalized brain networks on resting-state functional MRI after working memory training in people with HIV","volume":"57","author":"Jia","year":"2023","journal-title":"J. Magn. Reson. Imaging"},{"key":"10.1016\/j.cub.2025.06.050_bib67","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-024-55016-0","article-title":"Reward signals in the motor cortex: from biology to neurotechnology","volume":"16","author":"Derosiere","year":"2025","journal-title":"Nat. Commun."},{"key":"10.1016\/j.cub.2025.06.050_bib68","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.neuroimage.2013.06.061","article-title":"Characterising reward outcome signals in sensory cortex","volume":"83","author":"FitzGerald","year":"2013","journal-title":"NeuroImage"},{"key":"10.1016\/j.cub.2025.06.050_bib69","doi-asserted-by":"crossref","first-page":"5283","DOI":"10.1038\/s41467-024-49652-9","article-title":"Hippocampal and orbitofrontal neurons contribute to complementary aspects of associative structure","volume":"15","author":"Lin","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.cub.2025.06.050_bib70","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/j.neuron.2008.10.051","article-title":"Value-based modulations in human visual cortex","volume":"60","author":"Serences","year":"2008","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2025.06.050_bib71","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.neuron.2021.11.001","article-title":"Context-dependent persistency as a coding mechanism for robust and widely distributed value coding","volume":"110","author":"Hattori","year":"2022","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2025.06.050_bib72","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/j.neuron.2016.10.029","article-title":"Circuit mechanisms of sensorimotor learning","volume":"92","author":"Makino","year":"2016","journal-title":"Neuron"},{"key":"10.1016\/j.cub.2025.06.050_bib73","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1038\/nn.3993","article-title":"Learning-induced autonomy of sensorimotor systems","volume":"18","author":"Bassett","year":"2015","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.cub.2025.06.050_bib74","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1093\/cercor\/bhi005","article-title":"Human functional neuroimaging of brain changes associated with practice","volume":"15","author":"Kelly","year":"2005","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.cub.2025.06.050_bib75","doi-asserted-by":"crossref","first-page":"227","DOI":"10.3758\/LB.36.3.227","article-title":"Cognitive versus stimulus-response theories of learning","volume":"36","author":"Holland","year":"2008","journal-title":"Learn. Behav."},{"key":"10.1016\/j.cub.2025.06.050_bib76","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2021.661225","article-title":"What is learned in Pavlovian conditioning in crickets? Revisiting the S-S and S-R learning theories","volume":"15","author":"Mizunami","year":"2021","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.cub.2025.06.050_bib77","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1038\/npp.2009.131","article-title":"Human and rodent homologies in action control: corticostriatal determinants of goal-directed and habitual action","volume":"35","author":"Balleine","year":"2010","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.cub.2025.06.050_bib78","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.cobeha.2018.01.010","article-title":"Understanding the balance between goal-directed and habitual behavioral control","volume":"20","author":"Corbit","year":"2018","journal-title":"Curr. Opin. Behav. Sci."},{"key":"10.1016\/j.cub.2025.06.050_bib79","doi-asserted-by":"crossref","first-page":"349","DOI":"10.3758\/s13420-021-00488-z","article-title":"Context, attention, and the switch between habit and goal-direction in behavior","volume":"49","author":"Bouton","year":"2021","journal-title":"Learn. Behav."},{"key":"10.1016\/j.cub.2025.06.050_bib80","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1098\/rstb.1985.0010","article-title":"Actions and habits the development of behavioural autonomy","volume":"308","author":"Dickinson","year":"1985","journal-title":"Phil. Trans. R. Soc. Lond. B"},{"key":"10.1016\/j.cub.2025.06.050_bib81","doi-asserted-by":"crossref","DOI":"10.1126\/science.abg7277","article-title":"A neuronal mechanism for motivational control of behavior","volume":"375","author":"Courtin","year":"2022","journal-title":"Science"},{"key":"10.1016\/j.cub.2025.06.050_bib82","first-page":"271","article-title":"Omission learning after instrumental pretraining","volume":"51","author":"Dickinson","year":"1998","journal-title":"Q. J. Exp. Psychol."},{"key":"10.1016\/j.cub.2025.06.050_bib83","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1111\/j.1460-9568.2012.08050.x","article-title":"Habits, action sequences and reinforcement learning","volume":"35","author":"Dezfouli","year":"2012","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.cub.2025.06.050_bib84","doi-asserted-by":"crossref","first-page":"2039","DOI":"10.1523\/JNEUROSCI.1907-21.2022","article-title":"Opposing roles of the dorsolateral and dorsomedial striatum in the acquisition of skilled action sequencing in rats","volume":"42","author":"Turner","year":"2022","journal-title":"J. Neurosci."},{"key":"10.1016\/j.cub.2025.06.050_bib85","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/s41593-022-01210-6","article-title":"Disinhibition of the orbitofrontal cortex biases decision-making in obesity","volume":"26","author":"Seabrook","year":"2023","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.cub.2025.06.050_bib86","doi-asserted-by":"crossref","first-page":"3241","DOI":"10.1038\/s41596-021-00527-z","article-title":"Chronic, cortex-wide imaging of specific cell populations during behavior","volume":"16","author":"Couto","year":"2021","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.cub.2025.06.050_bib87","series-title":"Proceedings of the IEEE Int. Conf. Acoust., Speech, Signal Process.","first-page":"2581","article-title":"Consistent run selection for independent component analysis: application to fMRI analysis","author":"Long","year":"2018"},{"key":"10.1016\/j.cub.2025.06.050_bib88","doi-asserted-by":"crossref","DOI":"10.1038\/s42003-024-07088-3","article-title":"Comparison of whole-brain task-modulated functional connectivity methods for fMRI task connectomics","volume":"7","author":"Masharipov","year":"2024","journal-title":"Commun. Biol."}],"container-title":["Current Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960982225008103?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960982225008103?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T13:02:06Z","timestamp":1769778126000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960982225008103"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":88,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["S0960982225008103"],"URL":"https:\/\/doi.org\/10.1016\/j.cub.2025.06.050","relation":{},"ISSN":["0960-9822"],"issn-type":[{"value":"0960-9822","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Altered cortical dynamics and adaptive behavior following early-onset sucrose overconsumption","name":"articletitle","label":"Article Title"},{"value":"Current Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cub.2025.06.050","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}