{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T22:30:24Z","timestamp":1774650624423,"version":"3.50.1"},"reference-count":28,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2005,7,1]],"date-time":"2005-07-01T00:00:00Z","timestamp":1120176000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,21]],"date-time":"2013-07-21T00:00:00Z","timestamp":1374364800000},"content-version":"vor","delay-in-days":2942,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Therapeutic Research"],"published-print":{"date-parts":[[2005,7]]},"DOI":"10.1016\/j.curtheres.2005.08.010","type":"journal-article","created":{"date-parts":[[2005,10,10]],"date-time":"2005-10-10T11:07:21Z","timestamp":1128942441000},"page":"375-384","source":"Crossref","is-referenced-by-count":12,"title":["Effects of isoflurane, sevoflurane, and desflurane on platelet function: A prospective, randomized, single-blind, in vivo study"],"prefix":"10.1016","volume":"66","author":[{"given":"Nesrin","family":"Bozdogan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Halit","family":"Madenoglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kudret","family":"Dogru","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karamehmet","family":"Yildiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa S.","family":"Kotanoglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa","family":"Cetin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adem","family":"Boyaci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.curtheres.2005.08.010_bib1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.2174\/1389450023347759","article-title":"The effects of drugs used in anaesthesia on platelet membrane receptors and on platelet function","volume":"3","author":"Kozek-Langenecker","year":"2002","journal-title":"Curr Drug Targets"},{"key":"10.1016\/j.curtheres.2005.08.010_bib2","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1177\/0310057X9101900402","article-title":"The effects of anaesthetic agents on platelet function","volume":"19","author":"Gibbs","year":"1991","journal-title":"Anaesth Intensive Care"},{"key":"10.1016\/j.curtheres.2005.08.010_bib3","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1097\/00000542-197105000-00006","article-title":"The effect of volatile general anesthetics on adenosine diphosphate-induced platelet aggregation","volume":"34","author":"Ueda","year":"1971","journal-title":"Anesthesiology"},{"key":"10.1016\/j.curtheres.2005.08.010_bib4","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1002\/bjs.1800640217","article-title":"Platelet function tests during major operation for gastro-intestinal carcinoma","volume":"64","author":"Kokores","year":"1977","journal-title":"Br J Surg"},{"key":"10.1016\/j.curtheres.2005.08.010_bib5","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1213\/00000539-197907000-00006","article-title":"Platelet aggregation during and after general anesthesia and surgery","volume":"58","author":"Lichtenfeld","year":"1979","journal-title":"Anesth Analg"},{"key":"10.1016\/j.curtheres.2005.08.010_bib6","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1093\/bja\/56.11.1197","article-title":"Effect of volatile anaesthetics and nitrous oxidefentanyl anaesthesia on bleeding time","volume":"56","author":"Fyman","year":"1984","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.curtheres.2005.08.010_bib7","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1093\/bja\/53.10.1039","article-title":"Impaired platelet aggregation and increased bleeding time during general anesthesia with halothane","volume":"53","author":"Dalsgaard-Nielsen","year":"1981","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.curtheres.2005.08.010_bib8","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1213\/00000539-198611000-00012","article-title":"The in vitro and in vivo effects of isoflurane and nitrous oxide on platelet aggregation","volume":"65","author":"Fauss","year":"1986","journal-title":"Anesth Analg"},{"key":"10.1016\/j.curtheres.2005.08.010_bib9","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1177\/0310057X8701500306","article-title":"The effect of halothane general anaesthesia on platelet function","volume":"15","author":"Sweeney","year":"1987","journal-title":"Anaesth Intensive Care"},{"key":"10.1016\/j.curtheres.2005.08.010_bib10","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s005400050056","article-title":"Anesthesia with sevoflurane, but not isoflurane, prolongs bleeding time in humans","volume":"13","author":"Yokubol","year":"1999","journal-title":"J Anesth"},{"key":"10.1016\/j.curtheres.2005.08.010_bib11","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1213\/00000539-199902000-00039","article-title":"The in vitro effects of isoflurane, sevoflurane, and propofol on platelet aggregation","volume":"88","author":"Dogan","year":"1999","journal-title":"Anesth Analg"},{"key":"10.1016\/j.curtheres.2005.08.010_bib12","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1111\/j.1365-2141.2004.04859.x","article-title":"In vivo and in vitro effects of different anaesthetics on platelet function","volume":"125","author":"Dordoni","year":"2004","journal-title":"Br J Haematol"},{"key":"10.1016\/j.curtheres.2005.08.010_bib13","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1097\/00000542-200111000-00028","article-title":"Sevoflurane inhibits unstimulated and agonist-induced platelet antigen expression and platelet function in whole blood in vitro","volume":"95","author":"Horn","year":"2001","journal-title":"Anesthesiology"},{"key":"10.1016\/j.curtheres.2005.08.010_bib14","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1097\/00003643-199811000-00004","article-title":"Volatile anaesthetics induce changes in the expression of P-selectin and glycoprotein Ib on the surface of platelets in vitro","volume":"15","author":"Frohlich","year":"1998","journal-title":"Eur J Anaesthesiol"},{"key":"10.1016\/j.curtheres.2005.08.010_bib15","first-page":"S1","article-title":"The effect of general anesthesia with desflurane, sevoflurane or isoflurane on thrombocyte function","volume":"84","author":"Mielke","year":"1997","journal-title":"Anesth Analg"},{"key":"10.1016\/j.curtheres.2005.08.010_bib16","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1097\/00003643-200311000-00004","article-title":"Desflurane inhibits platelet function in vitro similar to halothane","volume":"20","author":"Berlet","year":"2003","journal-title":"Eur J Anaesthesiol"},{"key":"10.1016\/j.curtheres.2005.08.010_bib17","series-title":"Anesthesia","first-page":"74","article-title":"Uptake and distribution","author":"Eger","year":"2000"},{"key":"10.1016\/j.curtheres.2005.08.010_bib18","series-title":"Anesthesia","first-page":"96","article-title":"Cardiovascular pharmacology","author":"Pagel","year":"2000"},{"key":"10.1016\/j.curtheres.2005.08.010_bib19","series-title":"Anesthesia","first-page":"125","article-title":"Pulmonary pharmacology","author":"Pagel","year":"2000"},{"key":"10.1016\/j.curtheres.2005.08.010_bib20","first-page":"128","article-title":"Clinical Anesthesiology","author":"Morgan","year":"2002"},{"key":"10.1016\/j.curtheres.2005.08.010_bib21","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1097\/00000542-199612000-00027","article-title":"Sevoflurane inhibits human platelet aggregation and thromboxane A2 formation, possibly by suppression of cyclooxygenase activity","volume":"85","author":"Hirakata","year":"1996","journal-title":"Anesthesiology"},{"key":"10.1016\/j.curtheres.2005.08.010_bib22","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1097\/00000542-199607000-00014","article-title":"Direct inhibitory mechanisms of halothane on human platelet aggregation","volume":"85","author":"Kohro","year":"1996","journal-title":"Anesthesiology"},{"key":"10.1016\/j.curtheres.2005.08.010_bib23","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1038\/194927b0","article-title":"Aggregation of blood platelets by adenosine diphosphate and its reversal","volume":"9","author":"Born","year":"1962","journal-title":"Nature"},{"key":"10.1016\/j.curtheres.2005.08.010_bib24","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1097\/00000542-200001000-00028","article-title":"Sevoflurane does not inhibit human platelet aggregation induced by thrombin","volume":"92","author":"Nozuchi","year":"2000","journal-title":"Anesthesiology"},{"key":"10.1016\/j.curtheres.2005.08.010_bib25","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1213\/00000539-199704000-00040","article-title":"Propofol inhibits in vitro platelet aggregation in human whole blood","volume":"84","author":"De La Cruz","year":"1997","journal-title":"Anesth Analg"},{"issue":"Suppl 2","key":"10.1016\/j.curtheres.2005.08.010_bib26","first-page":"106","article-title":"Description of an in vitro platelet function analyzer-PFA-100","volume":"21","author":"Kundu","year":"1995","journal-title":"Semin Thromb Hemost"},{"key":"10.1016\/j.curtheres.2005.08.010_bib27","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1055\/s-2007-995840","article-title":"PFA 100 system: A new method for assessment of platelet dysfunction","volume":"24","author":"Mammen","year":"1998","journal-title":"Semin Thromb Hemost"},{"key":"10.1016\/j.curtheres.2005.08.010_bib28","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1007\/BF03013337","article-title":"Platelet aggregation is impaired during anaesthesia with sevoflurane but not with isoflurane","volume":"44","author":"Hirakata","year":"1997","journal-title":"Can J Anaesth"}],"container-title":["Current Therapeutic Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0011393X05000810?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0011393X05000810?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,5]],"date-time":"2023-05-05T01:37:47Z","timestamp":1683250667000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0011393X05000810"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,7]]},"references-count":28,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,7]]}},"alternative-id":["S0011393X05000810"],"URL":"https:\/\/doi.org\/10.1016\/j.curtheres.2005.08.010","relation":{},"ISSN":["0011-393X"],"issn-type":[{"value":"0011-393X","type":"print"}],"subject":[],"published":{"date-parts":[[2005,7]]}}}