{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T07:36:53Z","timestamp":1790235413840,"version":"4.1.0"},"reference-count":113,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,5,14]],"date-time":"2020-05-14T00:00:00Z","timestamp":1589414400000},"content-version":"am","delay-in-days":318,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100005825","name":"National Institute of Food and Agriculture","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005825","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011129","name":"North Dakota Agricultural Experiment Station","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Clinics of North America: Food Animal Practice"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1016\/j.cvfa.2019.02.006","type":"journal-article","created":{"date-parts":[[2019,5,15]],"date-time":"2019-05-15T18:28:21Z","timestamp":1557944901000},"page":"229-247","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":137,"title":["Developmental Programming of Fetal Growth and Development"],"prefix":"10.1016","volume":"35","author":[{"given":"Lawrence P.","family":"Reynolds","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawel P.","family":"Borowicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel S.","family":"Caton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew S.","family":"Crouse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl R.","family":"Dahlen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison K.","family":"Ward","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cvfa.2019.02.006_bib1","series-title":"Fetal and infant origins of adult disease","author":"Barker","year":"1992"},{"key":"10.1016\/j.cvfa.2019.02.006_bib2","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1098\/rstb.2004.1518","article-title":"Developmental origins of well being","volume":"359","author":"Barker","year":"2004","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib3","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1136\/bmj.310.6977.411","article-title":"Early origin of coronary heart disease (the \u201cBarker hypothesis\u201d)","volume":"1310","author":"Paneth","year":"1995","journal-title":"Br Med J"},{"key":"10.1016\/j.cvfa.2019.02.006_bib4","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1113\/jphysiol.2004.072009","article-title":"Developmental programming of the metabolic syndrome by maternal nutritional imbalance: how strong is the evidence from experimental models in mammals?","volume":"561","author":"Armitage","year":"2004","journal-title":"J\u00a0Physiol"},{"key":"10.1016\/j.cvfa.2019.02.006_bib5","doi-asserted-by":"crossref","first-page":"2316","DOI":"10.2527\/jas.2006-156","article-title":"Intrauterine growth retardation: implications for the animal sciences","volume":"84","author":"Wu","year":"2006","journal-title":"J\u00a0Anim Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib6","series-title":"Proc. 4th grazing livestock nutrition conference","first-page":"104","article-title":"Maternal plane of nutrition: impacts on fetal outcomes and postnatal offspring responses","author":"Caton","year":"2010"},{"issue":"13","key":"10.1016\/j.cvfa.2019.02.006_bib7","doi-asserted-by":"crossref","first-page":"E61","DOI":"10.2527\/jas.2009-2359","article-title":"Developmental programming: the concept, large animal models, and the key role of uteroplacental vascular development","volume":"88","author":"Reynolds","year":"2010","journal-title":"J\u00a0Anim Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib8","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.mce.2011.11.013","article-title":"Role of the pre- and post-natal environment in developmental programming of health and productivity","volume":"354","author":"Reynolds","year":"2012","journal-title":"Mol Cell Endocrinol"},{"issue":"2\u20133","key":"10.1016\/j.cvfa.2019.02.006_bib9","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1387\/ijdb.082799lr","article-title":"Uteroplacental vascular development and placental function: an update","volume":"54","author":"Reynolds","year":"2010","journal-title":"Int J Dev Biol"},{"key":"10.1016\/j.cvfa.2019.02.006_bib10","doi-asserted-by":"crossref","first-page":"12","DOI":"10.2527\/af.2017-0123","article-title":"Livestock as models for developmental programming","volume":"7","author":"Reynolds","year":"2017","journal-title":"Animal Frontiers"},{"key":"10.1016\/j.cvfa.2019.02.006_bib11","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1080\/14647270500320121","article-title":"Nutritional paradigms of ovine fetal growth restriction: implications for human pregnancy","volume":"8","author":"Luther","year":"2005","journal-title":"Hum Fertil"},{"issue":"a","key":"10.1016\/j.cvfa.2019.02.006_bib12","doi-asserted-by":"crossref","first-page":"S61","DOI":"10.1016\/j.placenta.2005.12.002","article-title":"Nutritional modulation of adolescent pregnancy outcome\u2013a review","volume":"27","author":"Wallace","year":"2006","journal-title":"Placenta"},{"key":"10.1016\/j.cvfa.2019.02.006_bib13","series-title":"Biology of domestic animals","first-page":"85","article-title":"Epigenetics and developmental programming in ruminants\u2013long-term impacts on growth and development","author":"Reynolds","year":"2017"},{"key":"10.1016\/j.cvfa.2019.02.006_bib14","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1126\/science.1251872","article-title":"The intergenerational transmission of inequality: maternal disadvantage and health at birth","volume":"344","author":"Aizer","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.cvfa.2019.02.006_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fgene.2011.00027","article-title":"Developmental programming in response to maternal overnutrition","volume":"2","author":"Alfaradhi","year":"2011","journal-title":"Front Genet"},{"issue":"Pt 1","key":"10.1016\/j.cvfa.2019.02.006_bib16","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1113\/jphysiol.2004.079756","article-title":"Experimental models of developmental programming: consequences of exposure to an energy rich diet during development","volume":"565","author":"Armitage","year":"2005","journal-title":"J\u00a0Physiol"},{"key":"10.1016\/j.cvfa.2019.02.006_bib17","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1016\/S0140-6736(14)60082-9","article-title":"Effect of smoke-free legislation on perinatal and child health: a systematic review and meta-analysis","volume":"383","author":"Been","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.cvfa.2019.02.006_bib18","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1111\/j.1365-2826.2010.01974.x","article-title":"Foetal hypothalamic and pituitary expression of gonadotrophin-releasing hormone and galanin systems is disturbed by exposure to sewage sludge chemicals via maternal ingestion","volume":"22","author":"Bellingham","year":"2010","journal-title":"J\u00a0Neuroendocrinol"},{"key":"10.1016\/j.cvfa.2019.02.006_bib19","doi-asserted-by":"crossref","first-page":"R175","DOI":"10.1530\/REP-13-0258","article-title":"Effects of maternal exposure to social stress during pregnancy: consequences for mother and offspring","volume":"146","author":"Brunton","year":"2013","journal-title":"Reproduction"},{"key":"10.1016\/j.cvfa.2019.02.006_bib20","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/j.fertnstert.2008.08.067","article-title":"Female reproductive disorders: the role of endocrine-disrupting compounds and developmental timing","volume":"90","author":"Crain","year":"2008","journal-title":"Fertil Steril"},{"key":"10.1016\/j.cvfa.2019.02.006_bib21","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1016\/j.theriogenology.2012.06.016","article-title":"Maternal environment and reproductive function of the offspring","volume":"78","author":"Dupont","year":"2012","journal-title":"Theriogenology"},{"key":"10.1016\/j.cvfa.2019.02.006_bib22","doi-asserted-by":"crossref","first-page":"3185","DOI":"10.2527\/jas.2014-7763","article-title":"Reproduction Symposium: does grazing on biosolids-treated pasture pose a pathophysiological risk associated with increased exposure to endocrine disrupting compounds?","volume":"92","author":"Evans","year":"2014","journal-title":"J\u00a0Anim Sci"},{"issue":"6","key":"10.1016\/j.cvfa.2019.02.006_bib23","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1113\/expphysiol.2008.046359","article-title":"Hormones as epigenetic signals in developmental programming","volume":"94","author":"Fowden","year":"2009","journal-title":"Exp Physiol"},{"key":"10.1016\/j.cvfa.2019.02.006_bib24","first-page":"29","article-title":"Intrauterine programming of physiological systems: causes and consequences","volume":"21","author":"Fowden","year":"2006","journal-title":"Physiology (Bethesda)"},{"key":"10.1016\/j.cvfa.2019.02.006_bib25","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.mce.2011.10.021","article-title":"Impact of endocrine-disrupting compounds (EDCs) on female reproductive health","volume":"355","author":"Fowler","year":"2012","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.cvfa.2019.02.006_bib26","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1177\/2042098614522682","article-title":"Antipsychotic drugs in pregnancy: a review of their maternal and fetal effects","volume":"52","author":"Galbally","year":"2014","journal-title":"Ther Adv Drug Saf"},{"key":"10.1016\/j.cvfa.2019.02.006_bib27","doi-asserted-by":"crossref","first-page":"734","DOI":"10.2527\/jas.2012-5769","article-title":"Effect of maternal activity during gestation on maternal behavior, fetal growth, umbilical blood flow, and farrowing characteristics in pigs","volume":"91","author":"Harris","year":"2013","journal-title":"J\u00a0Anim Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib28","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1038\/nrendo.2014.97","article-title":"Possible fetal determinants of male infertility","volume":"10","author":"Juul","year":"2014","journal-title":"Nat Rev Endocrinol"},{"key":"10.1016\/j.cvfa.2019.02.006_bib29","doi-asserted-by":"crossref","first-page":"592408","DOI":"10.1155\/2011\/592408","article-title":"Maternal obesity and developmental programming of metabolic disorders in offspring: evidence from animal models","volume":"2011","author":"Li","year":"2011","journal-title":"Exp Diabetes Res"},{"key":"10.1016\/j.cvfa.2019.02.006_bib30","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.yhbeh.2014.03.011","article-title":"Our stolen figures: the interface of sexual differentiation, endocrine disruptors, maternal programming, and energy balance","volume":"66","author":"Schneider","year":"2014","journal-title":"Horm Behav"},{"key":"10.1016\/j.cvfa.2019.02.006_bib31","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1186\/1471-2393-14-148","article-title":"Antenatal exercise in overweight and obese women and its effects on offspring and maternal health: design and rationale of the IMPROVE (Improving Maternal and Progeny Obesity Via Exercise) randomized controlled trial","volume":"14","author":"Seneviratne","year":"2014","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.cvfa.2019.02.006_bib32","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.mce.2014.07.019","article-title":"Endocrine disruptor induction of epigenetic transgenerational inheritance of disease","volume":"398","author":"Skinner","year":"2014","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.cvfa.2019.02.006_bib33","doi-asserted-by":"crossref","first-page":"2301","DOI":"10.2527\/jas.2011-4568","article-title":"Alpharma Beef Cattle Nutrition Symposium: implications of nutritional management for beef cow-calf systems","volume":"90","author":"Funston","year":"2012","journal-title":"J\u00a0Anim Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib34","doi-asserted-by":"crossref","first-page":"169","DOI":"10.3945\/an.115.010405","article-title":"The role of the small intestine in developmental programming: impact of maternal nutrition on the dam and offspring","volume":"7","author":"Meyer","year":"2016","journal-title":"Adv Nutr"},{"key":"10.1016\/j.cvfa.2019.02.006_bib35","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1017\/S1357729800050323","article-title":"Nutritional effects on foetal growth","volume":"68","author":"Robinson","year":"1999","journal-title":"Anim Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib36","series-title":"Nutrient requirements of beef cattle","author":"National Research Council (NRC)","year":"1996"},{"key":"10.1016\/j.cvfa.2019.02.006_bib37","series-title":"Nutrients requirements of small ruminants, sheep, goats, cervids and new world camelids","author":"National Research Council (NRC)","year":"2007"},{"key":"10.1016\/j.cvfa.2019.02.006_bib38","series-title":"The physiology of reproduction in the cow","author":"Hammond","year":"1927"},{"key":"10.1016\/j.cvfa.2019.02.006_bib39","first-page":"311","article-title":"The maternal effects on growth and conformation in Shire horse-Shetland pony crosses","volume":"125","author":"Walton","year":"1938","journal-title":"Proceedings of the Royal Society B"},{"issue":"Suppl. 1","key":"10.1016\/j.cvfa.2019.02.006_bib40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jas\/sky027.002","article-title":"Genetic parameters for lamb mortality associated with pneumonia","volume":"96","author":"Holland","year":"2018","journal-title":"J\u00a0Anim Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib41","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.livsci.2014.09.024","article-title":"Genetic analysis for gestation length, birth weight, weaning weight, and accumulated productivity in Nellore beef cattle","volume":"170","author":"Chud","year":"2014","journal-title":"Livest Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib42","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/bmb\/60.1.5","article-title":"The thrifty phenotype hypothesis","volume":"60","author":"Hales","year":"2001","journal-title":"Br Med Bull"},{"key":"10.1016\/j.cvfa.2019.02.006_bib43","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1111\/j.1469-185X.2006.00007.x","article-title":"The thrifty phenotype as an adaptive maternal effect","volume":"82","author":"Wells","year":"2007","journal-title":"Biol Rev Camb Philos Soc"},{"key":"10.1016\/j.cvfa.2019.02.006_bib44","doi-asserted-by":"crossref","first-page":"2085","DOI":"10.1007\/s00125-012-2589-y","article-title":"The thrifty phenotype hypothesis revisited","volume":"55","author":"Vaag","year":"2012","journal-title":"Diabetologia"},{"issue":"Pt 1","key":"10.1016\/j.cvfa.2019.02.006_bib45","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1113\/jphysiol.2005.104430","article-title":"Evidence for altered placental blood flow and vascularity in compromised pregnancies","volume":"572","author":"Reynolds","year":"2006","journal-title":"J\u00a0Physiol"},{"key":"10.1016\/j.cvfa.2019.02.006_bib46","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.placenta.2004.04.011","article-title":"Short communication: morphometric evidence that villous development and fetoplacental angiogenesis are compromised by intrauterine growth restriction but not by pre-eclampsia","volume":"25","author":"Mayhew","year":"2004","journal-title":"Placenta"},{"key":"10.1016\/j.cvfa.2019.02.006_bib47","first-page":"77","article-title":"A\u00a0stereological perspective on placental morphology in normal and complicated pregnancies","volume":"215","author":"Mayhew","year":"2009","journal-title":"J\u00a0Anat"},{"key":"10.1016\/j.cvfa.2019.02.006_bib48","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1095\/biolreprod.104.037234","article-title":"Influence of maternal nutrition on messenger RNA expression of placental angiogenic factors and their receptors at mid-gestation in adolescent sheep","volume":"72","author":"Redmer","year":"2005","journal-title":"Biol Reprod"},{"key":"10.1016\/j.cvfa.2019.02.006_bib49","doi-asserted-by":"crossref","first-page":"2464","DOI":"10.2527\/jas.2006-805","article-title":"Effect of early gestational undernutrition on angiogenic factor expression and vascularity in the bovine placentome","volume":"85","author":"Vonnahme","year":"2007","journal-title":"J\u00a0Anim Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib50","doi-asserted-by":"crossref","first-page":"2467","DOI":"10.2527\/jas.2012-5929","article-title":"Placental programming: how the maternal environment can impact placental function","volume":"91","author":"Vonnahme","year":"2013","journal-title":"J\u00a0Anim Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib51","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.theriogenology.2012.09.013","article-title":"Placental development during early pregnancy in sheep: effects of embryo origin on fetal and placental growth and global methylation","volume":"79","author":"Grazul-Bilska","year":"2013","journal-title":"Theriogenology"},{"key":"10.1016\/j.cvfa.2019.02.006_bib52","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1530\/REP-13-0663","article-title":"Placental development during early pregnancy in sheep: effects of embryo origin on vascularization","volume":"147","author":"Grazul-Bilska","year":"2014","journal-title":"Reproduction"},{"key":"10.1016\/j.cvfa.2019.02.006_bib53","doi-asserted-by":"crossref","first-page":"160","DOI":"10.2527\/tas2017.0019","article-title":"Impacts of maternal nutrition on placental vascularity and mRNA expression of angiogenic factors during the establishment of pregnancy in beef heifers","volume":"1","author":"McLean","year":"2017","journal-title":"Transl Anim Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib54","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.theriogenology.2016.04.042","article-title":"Maternal environment and placental vascularization in domestic ruminants","volume":"86","author":"Bairagi","year":"2016","journal-title":"Theriogenology"},{"key":"10.1016\/j.cvfa.2019.02.006_bib55","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1007\/s00125-012-2505-5","article-title":"Adipose tissue and fetal programming","volume":"55","author":"Symonds","year":"2012","journal-title":"Diabetologia"},{"key":"10.1016\/j.cvfa.2019.02.006_bib56","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/1440-1681.12505","article-title":"The role of maternal nutrition, metabolic function and the placental in developmental programming of renal dysfunction","volume":"43","author":"Richter","year":"2016","journal-title":"Clin Exp Pharmacol Physiol"},{"issue":"3","key":"10.1016\/j.cvfa.2019.02.006_bib57","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1463-1326.2012.01653.x","article-title":"Metabolic programming of insulin action and secretion","volume":"14","author":"Martin-Gronert","year":"2012","journal-title":"Diabetes Obes Metab"},{"key":"10.1016\/j.cvfa.2019.02.006_bib58","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1097\/GRF.0b013e31829e5b29","article-title":"Prenatal programming of insulin secretion in intrauterine growth restriction","volume":"56","author":"Gatford","year":"2013","journal-title":"Clin Obstet Gynecol"},{"key":"10.1016\/j.cvfa.2019.02.006_bib59","doi-asserted-by":"crossref","first-page":"E51","DOI":"10.2527\/jas.2009-2311","article-title":"Fetal programming of skeletal muscle development in ruminant animals","volume":"88","author":"Du","year":"2010","journal-title":"J\u00a0Anim Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib60","doi-asserted-by":"crossref","first-page":"583","DOI":"10.2527\/jas.2010-3386","article-title":"Fetal muscle development, mesenchymal multipotent cell differentiation and associated signaling pathways","volume":"89","author":"Du","year":"2011","journal-title":"J\u00a0Anim Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib61","series-title":"Researches on pre-natal life","author":"Barcroft","year":"1946"},{"key":"10.1016\/j.cvfa.2019.02.006_bib62","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0140-6736(97)07244-9","article-title":"Glucose tolerance in adults after prenatal exposure to famine","volume":"351","author":"Ravelli","year":"1998","journal-title":"Lancet"},{"issue":"Suppl","key":"10.1016\/j.cvfa.2019.02.006_bib63","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1038\/ng1089","article-title":"Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals","volume":"33","author":"Jaenisch","year":"2003","journal-title":"Nat Genet"},{"issue":"4","key":"10.1016\/j.cvfa.2019.02.006_bib64","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.tem.2009.12.007","article-title":"Epigenetic transgenerational actions of environmental factors in disease etiology","volume":"21","author":"Skinner","year":"2010","journal-title":"Trends Endocrinol Metab"},{"key":"10.1016\/j.cvfa.2019.02.006_bib65","doi-asserted-by":"crossref","first-page":"R528","DOI":"10.1152\/ajpregu.00316.2007","article-title":"Maternal obesity at conception programs obesity in the offspring","volume":"294","author":"Shankar","year":"2008","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.cvfa.2019.02.006_bib66","doi-asserted-by":"crossref","first-page":"2577","DOI":"10.1210\/en.2010-0017","article-title":"Maternal overweight programs insulin and adiponectin signaling in the offspring","volume":"151","author":"Shankar","year":"2010","journal-title":"Endocrinology"},{"key":"10.1016\/j.cvfa.2019.02.006_bib67","doi-asserted-by":"crossref","first-page":"3727","DOI":"10.2337\/db13-0433","article-title":"Maternal obesity induces epigenetic modifications to facilitate Zfp423 expression and enhance adipogenic differentiation in fetal mice","volume":"62","author":"Yang","year":"2013","journal-title":"Diabetes"},{"key":"10.1016\/j.cvfa.2019.02.006_bib68","doi-asserted-by":"crossref","first-page":"4113","DOI":"10.1210\/en.2012-2255","article-title":"Maternal obesity enhances white adipose tissue differentiation and alters genome-scale DNA methylation in male rat offspring","volume":"154","author":"Borengasser","year":"2013","journal-title":"Endocrinology"},{"key":"10.1016\/j.cvfa.2019.02.006_bib69","doi-asserted-by":"crossref","first-page":"3846","DOI":"10.2527\/jas.2014-7568","article-title":"Maternal overnutrition enhances mRNA expression of adipogenic markers and collagen deposition in skeletal muscle of beef cattle fetuses","volume":"92","author":"Duarte","year":"2014","journal-title":"J\u00a0Anim Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib70","doi-asserted-by":"crossref","first-page":"35","DOI":"10.2527\/jas.2014-8148","article-title":"Maternal nutrition during pregnancy is associated with differential expression of imprinted genes and DNA methyltransferases in muscle of beef cattle offspring","volume":"93","author":"Wang","year":"2015","journal-title":"J\u00a0Anim Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib71","doi-asserted-by":"crossref","first-page":"G1023","DOI":"10.1152\/ajpgi.00052.2010","article-title":"Epigenetics of programmed obesity: alteration of IUGR rat hepatic IGF1 mRNA expression and histone structure in rapid vs. delayed postnatal catch-up growth","volume":"299","author":"Tosh","year":"2010","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.cvfa.2019.02.006_bib72","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1017\/S000711450769196X","volume":"97","author":"Lillycrop","year":"2007","journal-title":"Br J Nutr"},{"key":"10.1016\/j.cvfa.2019.02.006_bib73","doi-asserted-by":"crossref","first-page":"564","DOI":"10.2174\/1570161111311050003","article-title":"Maternal stress and placental vascular function and remodeling","volume":"11","author":"Reynolds","year":"2013","journal-title":"Curr Vasc Pharmacol"},{"key":"10.1016\/j.cvfa.2019.02.006_bib74","series-title":"Advances in fetal and neonatal physiology","first-page":"193","article-title":"Placental vascular defects in compromised pregnancies: effects of assisted reproductive technologies and other maternal stressors","volume":"vol. 814","author":"Reynolds","year":"2014"},{"issue":"5","key":"10.1016\/j.cvfa.2019.02.006_bib75","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/S0093-691X(02)00935-4","article-title":"Morphology and morphometry of in\u00a0vivo- and in\u00a0vitro-produced bovine concepti from early pregnancy to term and association with high birth weights","volume":"58","author":"Bertolini","year":"2002","journal-title":"Theriogenology"},{"key":"10.1016\/j.cvfa.2019.02.006_bib76","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.theriogenology.2005.09.022","article-title":"Errors in development of fetuses and placentas from in\u00a0vitro-produced bovine embryos","volume":"65","author":"Farin","year":"2006","journal-title":"Theriogenology"},{"key":"10.1016\/j.cvfa.2019.02.006_bib77","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1016\/S0960-9822(01)00480-8","article-title":"Delayed and incomplete reprogramming of chromosome methylation patterns in bovine cloned embryos","volume":"11","author":"Bourc\u2019his","year":"2001","journal-title":"Curr Biol"},{"key":"10.1016\/j.cvfa.2019.02.006_bib78","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1095\/biolreprod.103.026559","article-title":"Effect of limited DNA methylation reprogramming in the normal sheep embryoon somatic cell nuclear transfer","volume":"71","author":"Beaujean","year":"2004","journal-title":"Biol Reprod"},{"key":"10.1016\/j.cvfa.2019.02.006_bib79","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.2527\/jas.2005-695","article-title":"Epigenetic characteristics of cloned and in\u00a0vitro-fertilized swamp buffalo (Bubalus bubalis) embryos","volume":"84","author":"Suteevun","year":"2006","journal-title":"J\u00a0Anim Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib80","doi-asserted-by":"crossref","first-page":"4460","DOI":"10.1093\/hmg\/dds287","article-title":"Gonadotropin stimulation contributes to an increased incidence of epimutations in ICSI-derived mice","volume":"21","author":"de Waal","year":"2012","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.cvfa.2019.02.006_bib81","doi-asserted-by":"crossref","first-page":"4163","DOI":"10.1073\/pnas.1201990109","article-title":"Primary epimutations introduced during intracytoplasmic sperm injection (ICSI) are corrected by germline-specific epigenetic reprogramming","volume":"109","author":"de Waal","year":"2012","journal-title":"Proc Natl Acad Sci U\u00a0S\u00a0A"},{"key":"10.1016\/j.cvfa.2019.02.006_bib82","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1354\/vp.45-6-865","article-title":"Review paper: a review of the pathology of abnormal placentae of somatic cell nuclear transfer clone pregnancies in cattle, sheep, and mice","volume":"45","author":"Palmieri","year":"2008","journal-title":"Vet Pathol"},{"key":"10.1016\/j.cvfa.2019.02.006_bib83","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.placenta.2009.07.007","article-title":"Unearthing the roles of imprinted genes in the placenta","volume":"30","author":"Bressan","year":"2009","journal-title":"Placenta"},{"key":"10.1016\/j.cvfa.2019.02.006_bib84","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.anireprosci.2012.10.030","article-title":"Influence of cloning by chromatin transfer on placental gene expression at Day 45 of pregnancy in cattle","volume":"136","author":"Mesquita","year":"2013","journal-title":"Anim Reprod Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib85","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1093\/humrep\/des397","article-title":"Post-implantation mortality of in\u00a0vitro produced embryos is associated with DNA methyltransferase I dysfunction in sheep placenta","volume":"28","author":"Ptak","year":"2013","journal-title":"Hum Reprod"},{"key":"10.1016\/j.cvfa.2019.02.006_bib86","doi-asserted-by":"crossref","first-page":"5089","DOI":"10.2527\/jas.2016-0761","article-title":"Technical note: a new surgical technique for ovariohysterectomy during early pregnancy in beef heifers","volume":"94","author":"McLean","year":"2016","journal-title":"J\u00a0Anim Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib87","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1093\/jas\/skx001","article-title":"The effects of nutrient restriction on mRNA expression of endogenous retroviruses, interferon-tau, and pregnancy specific protein-B during the establishment of pregnancy in beef heifers","volume":"96","author":"McLean","year":"2018","journal-title":"J\u00a0Anim Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib88","doi-asserted-by":"crossref","unstructured":"Crouse MS, Caton JS, Cushman RA, et al. Moderate nutrient restriction of beef heifers alters expression of genes associated with tissue metabolism, accretion, and function in fetal liver, muscle, and cerebrum by d 50 of gestation. Trans Anim Sci (In Press). doi: 10.1093\/tas\/txz026.","DOI":"10.1093\/tas\/txz026"},{"key":"10.1016\/j.cvfa.2019.02.006_bib89","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1530\/REP-08-0516","article-title":"J.\u00a0Fetoplacental growth and vascular development in overnourished adolescent sheep at day 50, 90 and 130 of gestation","volume":"137","author":"Redmer","year":"2009","journal-title":"Reproduction"},{"key":"10.1016\/j.cvfa.2019.02.006_bib90","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/S0093-691X(99)00264-2","article-title":"The effects of the early uterine environment on the subsequent development of embryo and fetus","volume":"53","author":"Barnes","year":"2000","journal-title":"Theriogenology"},{"key":"10.1016\/j.cvfa.2019.02.006_bib91","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.domaniend.2012.05.001","article-title":"Overfeeding and underfeeding have detrimental effects on oocyte quality measured by in\u00a0vitro fertilization and early embryonic development in sheep","volume":"43","author":"Grazul-Bilska","year":"2012","journal-title":"Domest Anim Endocrinol"},{"key":"10.1016\/j.cvfa.2019.02.006_bib92","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1126\/science.1080803","article-title":"A\u00a0periconceptional nutritional origin for noninfectious preterm birth","volume":"300","author":"Bloomfield","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.cvfa.2019.02.006_bib93","doi-asserted-by":"crossref","first-page":"R67","DOI":"10.1152\/ajpregu.00357.2004","article-title":"Effects of periconceptional undernutrition on the initiation of parturition in sheep","volume":"288","author":"Kumarasamy","year":"2005","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.cvfa.2019.02.006_bib94","first-page":"397","article-title":"The effects of maternal nutrition around the time of conception on the health of the offspring","volume":"64","author":"Oliver","year":"2007","journal-title":"Soc Reprod Fertil Suppl"},{"key":"10.1016\/j.cvfa.2019.02.006_bib95","doi-asserted-by":"crossref","first-page":"449","DOI":"10.2527\/2000.782449x","article-title":"Undegraded intake protein supplementation: I. Effects on forage utilization and performance of periparturient beef cows fed low-quality hay","volume":"78","author":"Sletmoen-Olson","year":"2000","journal-title":"J\u00a0Anim Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib96","first-page":"177","article-title":"Maternal dietary protein level alters function of large-conductance, calcium-activated k (bkca) channels in fetal coronary arterial smooth muscle cells","volume":"68","author":"O'Rourke","year":"2010","journal-title":"Pediatr Res"},{"key":"10.1016\/j.cvfa.2019.02.006_bib97","doi-asserted-by":"crossref","DOI":"10.2527\/jas.2009-2351","article-title":"Effects of maternal nutrition on conceptus growth and offspring performance: implications for beef cattle production","volume":"88","author":"Funston","year":"2010","journal-title":"J\u00a0Anim Sci"},{"issue":"2","key":"10.1016\/j.cvfa.2019.02.006_bib98","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.cvfa.2019.02.011","article-title":"Developmental programming in a beef production system","volume":"35","author":"Broadhead","year":"2019","journal-title":"Vet Clin Food Anim"},{"key":"10.1016\/j.cvfa.2019.02.006_bib99","doi-asserted-by":"crossref","first-page":"S106","DOI":"10.1093\/tas\/txy059","article-title":"Corn supplementation as a winter-feeding strategy alters maternal feeding behavior and endocrine profiles in mid- to late-gestating beef cows","volume":"2","author":"Tanner","year":"2018","journal-title":"Transl Anim Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib100","doi-asserted-by":"crossref","first-page":"2721","DOI":"10.2527\/jas.2006-785","article-title":"Effects of selenium supply and dietary restriction on maternal and fetal body weight, visceral organ mass, cellularity estimates, and jejunal vascularity in pregnant ewe lambs","volume":"85","author":"Reed","year":"2007","journal-title":"J\u00a0Anim Sci"},{"issue":"5","key":"10.1016\/j.cvfa.2019.02.006_bib101","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.2527\/jas.2009-2435","article-title":"Effects of plane of nutrition and selenium supply during gestation on ewe and neonatal offspring performance, body composition, and serum selenium","volume":"88","author":"Meyer","year":"2010","journal-title":"J\u00a0Anim Sci"},{"issue":"1","key":"10.1016\/j.cvfa.2019.02.006_bib102","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00726-009-0269-0","article-title":"Amino acids: metabolism, functions, and nutrition","volume":"37","author":"Wu","year":"2009","journal-title":"Amino Acids"},{"issue":"3","key":"10.1016\/j.cvfa.2019.02.006_bib103","first-page":"652","article-title":"Dietary L-arginine supplementation enhances the reproductive performance of gilts","volume":"137","author":"Mateo","year":"2007","journal-title":"J\u00a0Nutr"},{"issue":"7","key":"10.1016\/j.cvfa.2019.02.006_bib104","first-page":"1242","article-title":"Parenteral administration of L-arginine prevents fetal growth restriction in undernourished ewes","volume":"140","author":"Lassala","year":"2010","journal-title":"J\u00a0Nutr"},{"issue":"E-Suppl. 2","key":"10.1016\/j.cvfa.2019.02.006_bib105","first-page":"ii","article-title":"Impacts of L-arginine on ovarian function and reproductive performance in ewes","volume":"86","author":"Luther","year":"2008","journal-title":"J\u00a0Anim Sci"},{"key":"10.1016\/j.cvfa.2019.02.006_bib106","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1186\/s40104-018-0298-1","article-title":"Maternal supply of methionine during late-pregnancy enhances rate of Holstein calf development in utero and postnatal growth to a greater extent than colostrum source","volume":"9","author":"Alharthi","year":"2018","journal-title":"J\u00a0Anim Sci Biotechnol"},{"key":"10.1016\/j.cvfa.2019.02.006_bib107","doi-asserted-by":"crossref","first-page":"S7","DOI":"10.1111\/j.1753-4887.2008.00056.x","article-title":"The agouti mouse model: an epigenetic biosensor for nutritional and environmental alterations on the fetal epigenome","volume":"66","author":"Dolinoy","year":"2008","journal-title":"Nutr Rev"},{"key":"10.1016\/j.cvfa.2019.02.006_bib108","first-page":"2393S","article-title":"Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspring","volume":"132","author":"Cooney","year":"2002","journal-title":"J\u00a0Nutr"},{"key":"10.1016\/j.cvfa.2019.02.006_bib109","doi-asserted-by":"crossref","first-page":"e63549","DOI":"10.1371\/journal.pone.0063549","article-title":"Methyl donor supplementation blocks the adverse effects of maternal high fat diet on offspring physiology","volume":"8","author":"Carlin","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.cvfa.2019.02.006_bib110","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1093\/carcin\/bgs125","article-title":"Maternal high-methyl diet suppresses mammary carcinogenesis in female rat offspring","volume":"33","author":"Cho","year":"2012","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.cvfa.2019.02.006_bib111","first-page":"251","article-title":"Sildenafil citrate treatment enhances amino acid availability in the conceptus and fetal growth in an ovine model of intrauterine growth restriction","volume":"140","author":"Satterfield","year":"2010","journal-title":"J\u00a0Nutr"},{"key":"10.1016\/j.cvfa.2019.02.006_bib112","doi-asserted-by":"crossref","first-page":"R454","DOI":"10.1152\/ajpregu.00407.2011","article-title":"Melatonin supplementation alters uteroplacental hemodynamics and fetal development in an ovine model of intrauterine growth restriction","volume":"302","author":"Lemley","year":"2012","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"12","key":"10.1016\/j.cvfa.2019.02.006_bib113","doi-asserted-by":"crossref","first-page":"5100","DOI":"10.1093\/jas\/sky363","article-title":"Effect of chronic melatonin supplementation during mid to late gestation on maternal uterine artery blood flow and subsequent development of male offspring in beef cattle","volume":"96","author":"McCarty","year":"2018","journal-title":"J\u00a0Anim Sci"}],"container-title":["Veterinary Clinics of North America: Food Animal Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749072019300064?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749072019300064?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T03:49:36Z","timestamp":1760068176000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0749072019300064"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":113,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["S0749072019300064"],"URL":"https:\/\/doi.org\/10.1016\/j.cvfa.2019.02.006","relation":{},"ISSN":["0749-0720"],"issn-type":[{"value":"0749-0720","type":"print"}],"subject":[],"published":{"date-parts":[[2019,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Developmental Programming of Fetal Growth and Development","name":"articletitle","label":"Article Title"},{"value":"Veterinary Clinics of North America: Food Animal Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cvfa.2019.02.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}