{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T23:34:28Z","timestamp":1789601668202,"version":"build-2803163510"},"reference-count":79,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Clinics of North America: Food Animal Practice"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.cvfa.2023.02.004","type":"journal-article","created":{"date-parts":[[2023,4,7]],"date-time":"2023-04-07T15:33:26Z","timestamp":1680881606000},"page":"307-324","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":40,"title":["Hyperketonemia"],"prefix":"10.1016","volume":"39","author":[{"given":"Sabine","family":"Mann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica A.A.","family":"McArt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cvfa.2023.02.004_bib1","unstructured":"Udall DH. The practice of veterinary medicine: with one hundred and two illustrations. Ithaca, NY: Published by the author; 1943."},{"issue":"3","key":"10.1016\/j.cvfa.2023.02.004_bib2","first-page":"60","article-title":"Observations of acetonaemia of cattle","volume":"2","author":"Legard","year":"1938","journal-title":"Can J Comp Med"},{"issue":"6","key":"10.1016\/j.cvfa.2023.02.004_bib3","doi-asserted-by":"crossref","first-page":"974","DOI":"10.3168\/jds.S0022-0302(71)85953-2","article-title":"Clinical diagnosis and treatment of ketosis","volume":"54","author":"Fox","year":"1971","journal-title":"J\u00a0Dairy Sci"},{"issue":"10","key":"10.1016\/j.cvfa.2023.02.004_bib4","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1111\/j.1439-0442.1996.tb00491.x","article-title":"New aspects of ketone bodies in energy metabolism of dairy cows: a review","volume":"43","author":"Holtenius","year":"1996","journal-title":"Zentralbl Veterinarmed A"},{"issue":"1","key":"10.1016\/j.cvfa.2023.02.004_bib5","doi-asserted-by":"crossref","first-page":"701","DOI":"10.3168\/jds.2015-9908","article-title":"Dry period plane of energy: effects on glucose tolerance in transition dairy cows","volume":"99","author":"Mann","year":"2016","journal-title":"J\u00a0Dairy Sci"},{"issue":"2","key":"10.1016\/j.cvfa.2023.02.004_bib6","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S0749-0720(15)30102-X","article-title":"Ruminant adaptation to negative energy balance. Influences on the etiology of ketosis and fatty liver","volume":"16","author":"Herdt","year":"2000","journal-title":"Vet Clin North Am Food Anim Pract"},{"issue":"2","key":"10.1016\/j.cvfa.2023.02.004_bib7","doi-asserted-by":"crossref","first-page":"571","DOI":"10.3168\/jds.2008-1507","article-title":"Impact of hyperketonemia in early lactation dairy cows on health and production","volume":"92","author":"Duffield","year":"2009","journal-title":"J\u00a0Dairy Sci"},{"issue":"6","key":"10.1016\/j.cvfa.2023.02.004_bib8","doi-asserted-by":"crossref","first-page":"936","DOI":"10.3168\/jds.S0022-0302(71)85950-7","article-title":"Hyperketonemia-ketogenesis and ketone body metabolism","volume":"54","author":"Bergman","year":"1971","journal-title":"J\u00a0Dairy Sci"},{"issue":"6","key":"10.1016\/j.cvfa.2023.02.004_bib9","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1136\/vr.78.6.187","article-title":"Bovine ketosis","volume":"78","author":"Krebs","year":"1966","journal-title":"Vet Rec"},{"issue":"5","key":"10.1016\/j.cvfa.2023.02.004_bib10","first-page":"121","article-title":"Roles for insulin and glucagon in the development of ruminant ketosis - a review","volume":"20","author":"Brockman","year":"1979","journal-title":"Can Vet J"},{"issue":"4","key":"10.1016\/j.cvfa.2023.02.004_bib11","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1172\/JCI104949","article-title":"Effect of infused ketone bodies on glucose utilization in the dog","volume":"43","author":"Felts","year":"1964","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.cvfa.2023.02.004_bib12","first-page":"177","article-title":"Hypoglycemic action of ketones. I. Effects of ketones on hepatic glucose output and peripheral glucose utilization","volume":"63","author":"Mebane","year":"1964","journal-title":"J\u00a0Lab Clin Med"},{"issue":"1","key":"10.1016\/j.cvfa.2023.02.004_bib13","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0749-0720(15)30761-1","article-title":"Therapy of Diseases of Ruminant Intermediary Metabolism","volume":"8","author":"Herdt","year":"1992","journal-title":"Vet Clin North Am Food Anim Pract"},{"issue":"3","key":"10.1016\/j.cvfa.2023.02.004_bib14","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.3168\/jds.2016-11714","article-title":"Elevation of blood \u03b2-hydroxybutyrate concentration affects glucose metabolism in dairy cows before and after parturition","volume":"100","author":"Zarrin","year":"2017","journal-title":"J\u00a0Dairy Sci"},{"issue":"5","key":"10.1016\/j.cvfa.2023.02.004_bib15","doi-asserted-by":"crossref","first-page":"2960","DOI":"10.3168\/jds.2012-6224","article-title":"Long-term elevation of \u03b2-hydroxybutyrate in dairy cows through infusion: Effects on feed intake, milk production, and metabolism","volume":"96","author":"Zarrin","year":"2013","journal-title":"J\u00a0Dairy Sci"},{"key":"10.1016\/j.cvfa.2023.02.004_bib16","doi-asserted-by":"crossref","first-page":"700278","DOI":"10.3389\/fimmu.2021.700278","article-title":"Connecting metabolism to mastitis: Hyperketonemia impaired mammary gland defenses during a Streptococcus uberis challenge in dairy cattle","volume":"12","author":"Swartz","year":"2021","journal-title":"Front Immunol"},{"issue":"6","key":"10.1016\/j.cvfa.2023.02.004_bib17","first-page":"1174","article-title":"Hepatic ketogenesis and peripheral ketone body utilization in the ruminant","volume":"117","author":"Heitmann","year":"1987","journal-title":"J\u00a0Nutr"},{"issue":"3","key":"10.1016\/j.cvfa.2023.02.004_bib18","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.appet.2010.04.005","article-title":"Role of \u03b2-hydroxybutyric acid in the central regulation of energy balance","volume":"54","author":"Laeger","year":"2010","journal-title":"Appetite"},{"issue":"4","key":"10.1016\/j.cvfa.2023.02.004_bib19","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.3168\/jds.2009-2852","article-title":"Associations of elevated nonesterified fatty acids and beta-hydroxybutyrate concentrations with early lactation reproductive performance and milk production in transition dairy cattle in the northeastern United States","volume":"93","author":"Ospina","year":"2010","journal-title":"J\u00a0Dairy Sci"},{"issue":"10","key":"10.1016\/j.cvfa.2023.02.004_bib20","doi-asserted-by":"crossref","first-page":"5676","DOI":"10.3168\/jds.2011-5132","article-title":"Herd-level association of serum metabolites in the transition period with disease, milk production, and early lactation reproductive performance","volume":"95","author":"Chapinal","year":"2012","journal-title":"J\u00a0Dairy Sci"},{"issue":"9","key":"10.1016\/j.cvfa.2023.02.004_bib21","doi-asserted-by":"crossref","first-page":"5056","DOI":"10.3168\/jds.2012-5443","article-title":"Epidemiology of subclinical ketosis in early lactation dairy cattle","volume":"95","author":"McArt","year":"2012","journal-title":"J\u00a0Dairy Sci"},{"issue":"1","key":"10.1016\/j.cvfa.2023.02.004_bib22","doi-asserted-by":"crossref","first-page":"159","DOI":"10.3168\/jds.S0022-0302(05)72674-6","article-title":"Metabolic predictors of displaced abomasum in dairy cattle","volume":"88","author":"LeBlanc","year":"2005","journal-title":"J\u00a0Dairy Sci"},{"issue":"6","key":"10.1016\/j.cvfa.2023.02.004_bib23","doi-asserted-by":"crossref","first-page":"5349","DOI":"10.3168\/jds.2021-20863","article-title":"Transition cow nutrition and management strategies of dairy herds in the northeastern United States: Part II-Associations of metabolic- and inflammation-related analytes with health, milk yield, and reproduction","volume":"105","author":"Kerwin","year":"2022","journal-title":"J\u00a0Dairy Sci"},{"issue":"9","key":"10.1016\/j.cvfa.2023.02.004_bib24","doi-asserted-by":"crossref","first-page":"8527","DOI":"10.3168\/jds.2019-16477","article-title":"Hyperketolactia occurrence before or after artificial insemination is associated with a decreased pregnancy per artificial insemination in dairy cows","volume":"102","author":"Albaaj","year":"2019","journal-title":"J\u00a0Dairy Sci"},{"key":"10.1016\/j.cvfa.2023.02.004_bib25","doi-asserted-by":"crossref","first-page":"104908","DOI":"10.1016\/j.prevetmed.2020.104908","article-title":"Assessment of associations between transition diseases and reproductive performance of dairy cows using survival analysis and decision tree algorithms","volume":"176","author":"Bogado Pascottini","year":"2020","journal-title":"Prev Vet Med"},{"issue":"6","key":"10.1016\/j.cvfa.2023.02.004_bib26","doi-asserted-by":"crossref","first-page":"4808","DOI":"10.3168\/jds.2015-10154","article-title":"The effect of subclinical ketosis on activity at estrus and reproductive performance in dairy cattle","volume":"99","author":"Rutherford","year":"2016","journal-title":"J\u00a0Dairy Sci"},{"issue":"3","key":"10.1016\/j.cvfa.2023.02.004_bib27","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.tvjl.2013.08.011","article-title":"Elevated non-esterified fatty acids and \u03b2-hydroxybutyrate and their association with transition dairy cow performance","volume":"198","author":"McArt","year":"2013","journal-title":"Vet J"},{"issue":"12","key":"10.1016\/j.cvfa.2023.02.004_bib28","doi-asserted-by":"crossref","first-page":"7547","DOI":"10.3168\/jds.2014-8237","article-title":"Diseases, reproductive performance, and changes in milk production associated with subclinical ketosis in dairy cows: a meta-analysis and review","volume":"97","author":"Raboisson","year":"2014","journal-title":"J\u00a0Dairy Sci"},{"issue":"5","key":"10.1016\/j.cvfa.2023.02.004_bib29","doi-asserted-by":"crossref","first-page":"4410","DOI":"10.3168\/jds.2021-20836","article-title":"Assessment of milk yield and composition, early reproductive performance, and herd removal in multiparous dairy cattle based on the week of diagnosis of hyperketonemia in early lactation","volume":"105","author":"Rodriguez","year":"2022","journal-title":"J\u00a0Dairy Sci"},{"issue":"9","key":"10.1016\/j.cvfa.2023.02.004_bib30","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.2460\/javma.243.9.1329","article-title":"Association between \u03b2-hydroxybutyrate concentration at surgery for correction of left-displaced abomasum in dairy cows and removal from the herd after surgery","volume":"243","author":"Croushore","year":"2013","journal-title":"J\u00a0Am Vet Med Assoc"},{"issue":"6","key":"10.1016\/j.cvfa.2023.02.004_bib31","doi-asserted-by":"crossref","first-page":"3806","DOI":"10.3168\/jds.2014-9017","article-title":"Factors associated with survival in the herd for dairy cows following surgery to correct left displaced abomasum","volume":"98","author":"Reynen","year":"2015","journal-title":"J\u00a0Dairy Sci"},{"issue":"2","key":"10.1016\/j.cvfa.2023.02.004_bib32","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0749-0720(15)30103-1","article-title":"Subclinical ketosis in lactating dairy cattle","volume":"16","author":"Duffield","year":"2000","journal-title":"Vet Clin North Am Food Anim Pract"},{"issue":"5","key":"10.1016\/j.cvfa.2023.02.004_bib33","doi-asserted-by":"crossref","first-page":"3685","DOI":"10.3168\/jds.2016-12085","article-title":"Relationships between body condition score change, prior mid-lactation phenotypic residual feed intake, and hyperketonemia onset in transition dairy cows","volume":"100","author":"Rathbun","year":"2017","journal-title":"J\u00a0Dairy Sci"},{"issue":"7","key":"10.1016\/j.cvfa.2023.02.004_bib34","doi-asserted-by":"crossref","first-page":"5462","DOI":"10.3168\/jds.2016-12237","article-title":"Short communication: associations between blood glucose concentration, onset of hyperketonemia, and milk production in early lactation dairy cows","volume":"100","author":"Ruoff","year":"2017","journal-title":"J\u00a0Dairy Sci"},{"issue":"2","key":"10.1016\/j.cvfa.2023.02.004_bib35","doi-asserted-by":"crossref","first-page":"880","DOI":"10.3168\/jds.2014-8362","article-title":"Risk factors for subclinical and clinical ketosis and association with production parameters in dairy cows in the Netherlands","volume":"98","author":"Vanholder","year":"2015","journal-title":"J\u00a0Dairy Sci"},{"issue":"3","key":"10.1016\/j.cvfa.2023.02.004_bib36","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.3168\/jds.2011-4724","article-title":"The association of serum metabolites in the transition period with milk production and early-lactation reproductive performance","volume":"95","author":"Chapinal","year":"2012","journal-title":"J\u00a0Dairy Sci"},{"key":"10.1016\/j.cvfa.2023.02.004_bib37","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.rvsc.2022.01.003","article-title":"Global prevalence of subclinical ketosis in dairy cows: a systematic review and meta-analysis","volume":"144","author":"Loiklung","year":"2022","journal-title":"Res Vet Sci"},{"issue":"1","key":"10.1016\/j.cvfa.2023.02.004_bib38","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1080\/00480169.2013.823829","article-title":"Prevalence of subclinical ketosis in mainly pasture-grazed dairy cows in New Zealand in early lactation","volume":"62","author":"Compton","year":"2014","journal-title":"N\u00a0Z Vet J"},{"key":"10.1016\/j.cvfa.2023.02.004_bib39","doi-asserted-by":"crossref","first-page":"104855","DOI":"10.1016\/j.prevetmed.2019.104855","article-title":"Blood beta-hydroxybutyrate concentrations and early lactation management strategies on pasture-based dairy farms in Colombia","volume":"174","author":"Leal Yepes","year":"2020","journal-title":"Prev Vet Med"},{"issue":"9","key":"10.1016\/j.cvfa.2023.02.004_bib40","doi-asserted-by":"crossref","first-page":"6284","DOI":"10.3168\/jds.2015-9446","article-title":"Short communication: Concentrations of nonesterified fatty acids and beta-hydroxybutyrate in dairy cows are not well correlated during the transition period","volume":"98","author":"McCarthy","year":"2015","journal-title":"J\u00a0Dairy Sci"},{"issue":"1","key":"10.1016\/j.cvfa.2023.02.004_bib41","doi-asserted-by":"crossref","first-page":"198","DOI":"10.3168\/jds.2012-5681","article-title":"Dry period and parturient predictors of early lactation hyperketonemia in dairy cattle","volume":"96","author":"McArt","year":"2013","journal-title":"J\u00a0Dairy Sci"},{"issue":"3","key":"10.1016\/j.cvfa.2023.02.004_bib42","doi-asserted-by":"crossref","first-page":"2476","DOI":"10.3168\/jds.2017-13209","article-title":"Predicting hyperketonemia by logistic and linear regression using test-day milk and performance variables in early-lactation Holstein and Jersey cows","volume":"101","author":"Chandler","year":"2018","journal-title":"J\u00a0Dairy Sci"},{"issue":"6","key":"10.1016\/j.cvfa.2023.02.004_bib43","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.3168\/jds.S0022-0302(01)70170-1","article-title":"Body condition related to ketosis and reproductive performance in norwegian dairy cows","volume":"84","author":"Gillund","year":"2001","journal-title":"J\u00a0Dairy Sci"},{"issue":"12","key":"10.1016\/j.cvfa.2023.02.004_bib44","doi-asserted-by":"crossref","first-page":"8818","DOI":"10.3168\/jds.2015-9667","article-title":"Technical note: Validation of a handheld meter for measuring beta-hydroxybutyrate concentrations in plasma and serum from dairy cows","volume":"98","author":"Pineda","year":"2015","journal-title":"J\u00a0Dairy Sci"},{"issue":"7","key":"10.1016\/j.cvfa.2023.02.004_bib45","doi-asserted-by":"crossref","first-page":"6455","DOI":"10.3168\/jds.2017-13960","article-title":"Technical note: Evaluation of the diagnostic accuracy of 2 point-of-care beta-hydroxybutyrate devices in stored bovine plasma at room temperature and at 37 degrees C","volume":"101","author":"Leal Yepes","year":"2018","journal-title":"J\u00a0Dairy Sci"},{"issue":"12","key":"10.1016\/j.cvfa.2023.02.004_bib46","doi-asserted-by":"crossref","first-page":"7719","DOI":"10.3168\/jds.2013-7121","article-title":"Comparison of 2 electronic cowside tests to detect subclinical ketosis in dairy cows and the influence of the temperature and type of blood sample on the test results","volume":"96","author":"Iwersen","year":"2013","journal-title":"J\u00a0Dairy Sci"},{"issue":"6","key":"10.1016\/j.cvfa.2023.02.004_bib47","doi-asserted-by":"crossref","first-page":"2618","DOI":"10.3168\/jds.2008-1795","article-title":"Evaluation of an electronic cowside test to detect subclinical ketosis in dairy cows","volume":"92","author":"Iwersen","year":"2009","journal-title":"J\u00a0Dairy Sci"},{"issue":"11","key":"10.1016\/j.cvfa.2023.02.004_bib48","doi-asserted-by":"crossref","first-page":"9136","DOI":"10.3168\/jds.2016-11077","article-title":"Technical note: Comparison of 4 electronic handheld meters for diagnosing hyperketonemia in dairy cows","volume":"99","author":"Bach","year":"2016","journal-title":"J\u00a0Dairy Sci"},{"issue":"2","key":"10.1016\/j.cvfa.2023.02.004_bib49","doi-asserted-by":"crossref","first-page":"1524","DOI":"10.3168\/jds.2017-13583","article-title":"Technical note: Validation of the BHBCheck blood beta-hydroxybutyrate meter as a diagnostic tool for hyperketonemia in dairy cows","volume":"101","author":"Sailer","year":"2018","journal-title":"J\u00a0Dairy Sci"},{"issue":"9","key":"10.1016\/j.cvfa.2023.02.004_bib50","doi-asserted-by":"crossref","first-page":"7719","DOI":"10.3168\/jds.2021-21590","article-title":"An investigation of blood, milk, and urine test patterns for the diagnosis of ketosis in dairy cows in early lactation","volume":"105","author":"Serrenho","year":"2022","journal-title":"J\u00a0Dairy Sci"},{"issue":"11","key":"10.1016\/j.cvfa.2023.02.004_bib51","first-page":"713","article-title":"Use of test day milk fat and milk protein to detect subclinical ketosis in dairy cattle in Ontario","volume":"38","author":"Duffield","year":"1997","journal-title":"Can Vet J"},{"issue":"12","key":"10.1016\/j.cvfa.2023.02.004_bib52","doi-asserted-by":"crossref","first-page":"10398","DOI":"10.3168\/jds.2017-13054","article-title":"A\u00a0100-Year Review: Metabolic health indicators and management of dairy cattle","volume":"100","author":"Overton","year":"2017","journal-title":"J\u00a0Dairy Sci"},{"issue":"11","key":"10.1016\/j.cvfa.2023.02.004_bib53","doi-asserted-by":"crossref","first-page":"10129","DOI":"10.3168\/jds.2019-16926","article-title":"Association of mid-infrared-predicted milk and blood constituents with early-lactation disease, removal, and production outcomes in Holstein cows","volume":"102","author":"Bach","year":"2019","journal-title":"J\u00a0Dairy Sci"},{"issue":"2","key":"10.1016\/j.cvfa.2023.02.004_bib54","first-page":"196","article-title":"Opportunities and limitations of milk mid-infrared spectra-based estimation of acetone and \u03b2-hydroxybutyrate for the prediction of metabolic stress and ketosis in dairy cows","volume":"87","author":"Caldeira","year":"2020","journal-title":"J\u00a0Dairy Res"},{"issue":"1","key":"10.1016\/j.cvfa.2023.02.004_bib55","doi-asserted-by":"crossref","first-page":"818","DOI":"10.3168\/jds.2020-18930","article-title":"Effect of hyperketonemia on the diurnal patterns of energy-related blood metabolites in early-lactation dairy cows","volume":"104","author":"Seely","year":"2021","journal-title":"J\u00a0Dairy Sci"},{"issue":"1","key":"10.1016\/j.cvfa.2023.02.004_bib56","doi-asserted-by":"crossref","first-page":"291","DOI":"10.3168\/jds.2013-7099","article-title":"Effects of time and sampling location on concentrations of beta-hydroxybutyric acid in dairy cows","volume":"97","author":"Mahrt","year":"2014","journal-title":"J\u00a0Dairy Sci"},{"issue":"9","key":"10.1016\/j.cvfa.2023.02.004_bib57","doi-asserted-by":"crossref","first-page":"7362","DOI":"10.3168\/jds.2016-10911","article-title":"Measurement of beta-hydroxybutyrate in capillary blood obtained from an ear to detect hyperketonemia in dairy cows by using an electronic handheld device","volume":"99","author":"Suss","year":"2016","journal-title":"J\u00a0Dairy Sci"},{"issue":"9","key":"10.1016\/j.cvfa.2023.02.004_bib58","doi-asserted-by":"crossref","first-page":"6108","DOI":"10.3168\/jds.2014-8957","article-title":"Suitability of capillary blood obtained by a minimally invasive lancet technique to detect subclinical ketosis in dairy cows by using 3 different electronic hand-held devices","volume":"98","author":"Kanz","year":"2015","journal-title":"J\u00a0Dairy Sci"},{"issue":"7","key":"10.1016\/j.cvfa.2023.02.004_bib59","doi-asserted-by":"crossref","first-page":"5717","DOI":"10.3168\/jds.2016-12011","article-title":"Short communication: repeatability of beta-hydroxybutyrate measurements in capillary blood obtained from the external vulvar skin","volume":"100","author":"Iwersen","year":"2017","journal-title":"J\u00a0Dairy Sci"},{"issue":"2","key":"10.1016\/j.cvfa.2023.02.004_bib60","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.cvfa.2013.04.003","article-title":"Using nonesterified fatty acids and \u03b2-hydroxybutyrate concentrations during the transition period for herd-level monitoring of increased risk of disease and decreased reproductive and milking performance","volume":"29","author":"Ospina","year":"2013","journal-title":"Vet Clin North Am Food Anim Pract"},{"issue":"7","key":"10.1016\/j.cvfa.2023.02.004_bib61","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1136\/inp.m3094","article-title":"Metabolic disease testing on farms: epidemiological principles","volume":"42","author":"McArt","year":"2020","journal-title":"Practice"},{"issue":"2","key":"10.1016\/j.cvfa.2023.02.004_bib62","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.cvfa.2013.03.001","article-title":"Ketosis treatment in lactating dairy cattle","volume":"29","author":"Gordon","year":"2013","journal-title":"Vet Clin North Am Food Anim Pract"},{"issue":"8","key":"10.1016\/j.cvfa.2023.02.004_bib63","doi-asserted-by":"crossref","first-page":"6470","DOI":"10.3168\/jds.2016-12532","article-title":"The effect of different treatments for early-lactation hyperketonemia on blood beta-hydroxybutyrate, plasma nonesterified fatty acids, glucose, insulin, and glucagon in dairy cattle","volume":"100","author":"Mann","year":"2017","journal-title":"J\u00a0Dairy Sci"},{"issue":"10","key":"10.1016\/j.cvfa.2023.02.004_bib64","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.3168\/jds.S0022-0302(64)88848-2","article-title":"Detection, occurrence, and prophylactic treatment of borderline ketosis with propylene glycol feeding1","volume":"47","author":"Emery","year":"1964","journal-title":"J\u00a0Dairy Sci"},{"issue":"12","key":"10.1016\/j.cvfa.2023.02.004_bib65","doi-asserted-by":"crossref","first-page":"6011","DOI":"10.3168\/jds.2011-4463","article-title":"A\u00a0field trial on the effect of propylene glycol on milk yield and resolution of ketosis in fresh cows diagnosed with subclinical ketosis","volume":"94","author":"McArt","year":"2011","journal-title":"J\u00a0Dairy Sci"},{"issue":"2004","key":"10.1016\/j.cvfa.2023.02.004_bib66","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.anifeedsci.2004.03.008","article-title":"Propylene glycol for dairy cows: a review of the metabolism of propylene glycol and its effects on physiological parameters, feed intake, milk production and risk of ketosis","volume":"115","author":"Nielsen","year":"2004","journal-title":"Anim Feed Sci Tech"},{"issue":"5","key":"10.1016\/j.cvfa.2023.02.004_bib67","doi-asserted-by":"crossref","first-page":"2505","DOI":"10.3168\/jds.2011-4908","article-title":"A\u00a0field trial on the effect of propylene glycol on displaced abomasum, removal from herd, and reproduction in fresh cows diagnosed with subclinical ketosis","volume":"95","author":"McArt","year":"2012","journal-title":"J\u00a0Dairy Sci"},{"issue":"5","key":"10.1016\/j.cvfa.2023.02.004_bib68","doi-asserted-by":"crossref","first-page":"3912","DOI":"10.3168\/jds.2016-11926","article-title":"Randomized clinical field trial on the effects of butaphosphan-cyanocobalamin and propylene glycol on ketosis resolution and milk production","volume":"100","author":"Gordon","year":"2017","journal-title":"J\u00a0Dairy Sci"},{"issue":"2","key":"10.1016\/j.cvfa.2023.02.004_bib69","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.3168\/jds.2020-19111","article-title":"A\u00a0randomized controlled trial to evaluate propylene glycol alone or in combination with dextrose as a treatment for hyperketonemia in dairy cows","volume":"104","author":"Capel","year":"2021","journal-title":"J\u00a0Dairy Sci"},{"issue":"11","key":"10.1016\/j.cvfa.2023.02.004_bib70","doi-asserted-by":"crossref","first-page":"8991","DOI":"10.3168\/jds.2016-11358","article-title":"A\u00a0randomized controlled trial of dexamethasone as an adjunctive therapy to propylene glycol for treatment of hyperketonemia in postpartum dairy cattle","volume":"99","author":"Tatone","year":"2016","journal-title":"J\u00a0Dairy Sci"},{"issue":"2","key":"10.1016\/j.cvfa.2023.02.004_bib71","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.3168\/jds.2021-20551","article-title":"Reducing milking frequency from twice to once daily as an adjunct treatment for ketosis in lactating dairy cows-A randomized controlled trial","volume":"105","author":"Williamson","year":"2022","journal-title":"J\u00a0Dairy Sci"},{"issue":"11","key":"10.1016\/j.cvfa.2023.02.004_bib72","doi-asserted-by":"crossref","first-page":"9070","DOI":"10.3168\/jds.2021-21328","volume":"105","author":"Hubner","year":"2022","journal-title":"J\u00a0Dairy Sci"},{"issue":"4","key":"10.1016\/j.cvfa.2023.02.004_bib73","doi-asserted-by":"crossref","first-page":"2954","DOI":"10.3168\/jds.2016-11925","article-title":"Effects of a combination butaphosphan and cyanocobalamin product and insulin on ketosis resolution and milk production","volume":"100","author":"Gordon","year":"2017","journal-title":"J\u00a0Dairy Sci"},{"issue":"5","key":"10.1016\/j.cvfa.2023.02.004_bib74","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1136\/inp.l3041","article-title":"Production-related metabolic disorders of cattle: ketosis, milk fever and grass staggers","volume":"41","author":"Mann","year":"2019","journal-title":"Practice"},{"issue":"4","key":"10.1016\/j.cvfa.2023.02.004_bib75","doi-asserted-by":"crossref","first-page":"3348","DOI":"10.3168\/jds.2018-15386","article-title":"Associations of pre- and postpartum lying time with metabolic, inflammation, and health status of lactating dairy cows","volume":"102","author":"Pineiro","year":"2019","journal-title":"J\u00a0Dairy Sci"},{"issue":"4","key":"10.1016\/j.cvfa.2023.02.004_bib76","doi-asserted-by":"crossref","first-page":"4575","DOI":"10.3168\/jds.2020-18792","article-title":"Prepartum behavior changes in dry Holstein cows at risk of postpartum diseases","volume":"104","author":"Belaid","year":"2021","journal-title":"J\u00a0Dairy Sci"},{"issue":"7","key":"10.1016\/j.cvfa.2023.02.004_bib77","doi-asserted-by":"crossref","first-page":"5604","DOI":"10.3168\/jds.2015-10509","article-title":"Association of rumination time with subclinical ketosis in transition dairy cows","volume":"99","author":"Kaufman","year":"2016","journal-title":"J\u00a0Dairy Sci"},{"issue":"6","key":"10.1016\/j.cvfa.2023.02.004_bib78","doi-asserted-by":"crossref","first-page":"5657","DOI":"10.3168\/jds.2018-15508","article-title":"Effect of rumen-protected branched-chain amino acid supplementation on production- and energy-related metabolites during the first 35\u00a0days in milk in Holstein dairy cows","volume":"102","author":"Leal Yepes","year":"2019","journal-title":"J\u00a0Dairy Sci"},{"issue":"7","key":"10.1016\/j.cvfa.2023.02.004_bib79","doi-asserted-by":"crossref","first-page":"1988","DOI":"10.3390\/ani11071988","article-title":"The use of monensin for ketosis prevention in dairy cows during the transition period: a systematic review","volume":"11","author":"Mammi","year":"2021","journal-title":"Animals"}],"container-title":["Veterinary Clinics of North America: Food Animal Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749072023000154?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749072023000154?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T03:52:27Z","timestamp":1760068347000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0749072023000154"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":79,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["S0749072023000154"],"URL":"https:\/\/doi.org\/10.1016\/j.cvfa.2023.02.004","relation":{},"ISSN":["0749-0720"],"issn-type":[{"value":"0749-0720","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hyperketonemia","name":"articletitle","label":"Article Title"},{"value":"Veterinary Clinics of North America: Food Animal Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cvfa.2023.02.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}