{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T13:31:15Z","timestamp":1762263075840,"version":"build-2065373602"},"reference-count":67,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Clinics of North America: Small Animal Practice"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.cvsm.2025.06.017","type":"journal-article","created":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T20:11:09Z","timestamp":1756152669000},"page":"1159-1175","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Integrative Veterinary Oncology"],"prefix":"10.1016","volume":"55","author":[{"given":"Betsy","family":"Hershey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.cvsm.2025.06.017_bib1","doi-asserted-by":"crossref","first-page":"e555","DOI":"10.1016\/S2214-109X(18)30127-X","article-title":"Changing cancer survival in China during 2003-15: a pooled analysis of 17 population-based cancer registries","volume":"6","author":"Zhang","year":"2018","journal-title":"Lancet Glob Health"},{"issue":"5","key":"10.1016\/j.cvsm.2025.06.017_bib2","doi-asserted-by":"crossref","first-page":"361","DOI":"10.5326\/0420361","article-title":"The use of complementary and alternative therapies in dogs and cats with cancer","volume":"42","author":"Lana","year":"2006","journal-title":"J Am Animal Hosp Assoc"},{"key":"10.1016\/j.cvsm.2025.06.017_bib3","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.jams.2019.04.002","article-title":"Canine and feline patients referred exclusively for acupuncture and herbs: a two year retrospective analysis","volume":"5","author":"Schmalberg","year":"2019","journal-title":"J Acupunct Meridian Stud"},{"issue":"5","key":"10.1016\/j.cvsm.2025.06.017_bib4","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1111\/jvim.16825","article-title":"Changes in diet and supplement use in dogs with cancer","volume":"37","author":"Kramer","year":"2023","journal-title":"J Vet Intern Med"},{"issue":"2","key":"10.1016\/j.cvsm.2025.06.017_bib5","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1001\/jama.293.2.194","article-title":"Fasting serum glucose level and cancer risk in Korean men and women","volume":"293","author":"Ha Jee","year":"2005","journal-title":"JAMA"},{"issue":"Suppl 1","key":"10.1016\/j.cvsm.2025.06.017_bib6","first-page":"37S","article-title":"Ketogenic diets and cancer: emerging evidence","volume":"34","author":"Tan-Shalaby","year":"2017","journal-title":"Fed Pract"},{"key":"10.1016\/j.cvsm.2025.06.017_bib7","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.molmet.2019.06.026","article-title":"Ketogenic diet in the treatment of cancer-where do we stand","volume":"33","author":"Weber","year":"2020","journal-title":"Mol Metab"},{"issue":"6","key":"10.1016\/j.cvsm.2025.06.017_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0065522","article-title":"The ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer","volume":"8","author":"Poff","year":"2013","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.cvsm.2025.06.017_bib9","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1016\/j.nut.2012.05.001","article-title":"Targeting insulin inhibition as a metabolic therapy in advanced cancer: a pilot safety and feasibility dietary trial in 10 patients","volume":"28","author":"Fine","year":"2012","journal-title":"Nutrition"},{"issue":"2","key":"10.1016\/j.cvsm.2025.06.017_bib10","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1111\/jpn.13913","article-title":"Ketogenic diets: a systematic review of current scientific evidence and possible applicability in dogs and cats","volume":"108","author":"Vendramini","year":"2024","journal-title":"J Anim Physiol Anim Nutr"},{"key":"10.1016\/j.cvsm.2025.06.017_bib11","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2023.1157517","article-title":"Case report: resolution of malignant canine mast cell tumor using ketogenic metabolic therapy alone","volume":"10","author":"Seyfried","year":"2023","journal-title":"Front Nutr"},{"issue":"2","key":"10.1016\/j.cvsm.2025.06.017_bib12","first-page":"148","article-title":"Acceptance of a novel, highly palatable, calorically dense, and nutritionally complete diet in dogs with benign and malignant tumors Vet","volume":"10","author":"Anthony","year":"2023","journal-title":"Sci"},{"issue":"7","key":"10.1016\/j.cvsm.2025.06.017_bib13","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1142\/S0192415X20500780","article-title":"Positive role of Chinese herbal medicine in cancer immune regulation","volume":"48","author":"Wang","year":"2020","journal-title":"Am J Chin Med"},{"key":"10.1016\/j.cvsm.2025.06.017_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2019.109570","article-title":"Antitumor effects of immunity-enhancing traditional Chinese medicine","volume":"121","author":"Wang","year":"2020","journal-title":"Biomed Pharmacother"},{"issue":"12","key":"10.1016\/j.cvsm.2025.06.017_bib15","first-page":"3379","article-title":"Topical Yunnan Baiyao administration as an adjunctive therapy for bleeding complications in adolescents with advanced cancer","volume":"20","author":"Ladas","year":"2012","journal-title":"Support Care Cancer"},{"issue":"3","key":"10.1016\/j.cvsm.2025.06.017_bib16","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1111\/vco.12100","article-title":"In vitro effects of Yunnan Baiyao on canine hemangiosarcoma cell lines","volume":"14","author":"Wirth","year":"2016","journal-title":"Vet Comp Oncol"},{"key":"10.1016\/j.cvsm.2025.06.017_bib66","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1186\/1471-2407-9-451","article-title":"Survival of cancer patients treated with mistletoe extract (Iscador): a systematic literature review","volume":"9","author":"Ostermann","year":"2009","journal-title":"BMC Cancer"},{"key":"10.1016\/j.cvsm.2025.06.017_bib67","doi-asserted-by":"crossref","first-page":"4628287","DOI":"10.1155\/2016\/4628287","article-title":"Intravenous mistletoe treatment in integrative cancer care: a qualitative study exploring the procedures, concepts, and observations of expert doctors","volume":"2016","author":"Kienle","year":"2016","journal-title":"Evid Based Complement Alternat Med"},{"issue":"1","key":"10.1016\/j.cvsm.2025.06.017_bib17","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1186\/s12957-021-02293-4","article-title":"Effect of mistletoe extract on tumor response in neoadjuvant chemoradiotherapy for rectal cancer: a cohort study","volume":"19","author":"Baek","year":"2021","journal-title":"World J Surg Oncol"},{"issue":"2","key":"10.1016\/j.cvsm.2025.06.017_bib18","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1158\/2767-9764.CRC-23-0002","article-title":"Phase I trial of intravenous mistletoe extract in advanced cancer","volume":"3","author":"Paller","year":"2023","journal-title":"Cancer Res Commun"},{"issue":"1","key":"10.1016\/j.cvsm.2025.06.017_bib19","first-page":"31","article-title":"European mistletoe (Viscum album) extract is cytotoxic to canine high-grade astrocytoma cells in vitro and has additive effects with mebendazole","volume":"9","author":"Wright","year":"2022","journal-title":"Vet Sci"},{"issue":"6","key":"10.1016\/j.cvsm.2025.06.017_bib20","first-page":"349","article-title":"Postsurgical adjuvant treatment with mistletoe extract (Viscum album ssp. album) in canine mammary tumors","volume":"24","author":"Biegel","year":"2017","journal-title":"Compl Med Res"},{"issue":"18","key":"10.1016\/j.cvsm.2025.06.017_bib21","first-page":"1392","article-title":"Mistletoe in adjuvant cancer treatment in companion animals","volume":"85","author":"Biegel","year":"2019","journal-title":"Planta Med"},{"issue":"7","key":"10.1016\/j.cvsm.2025.06.017_bib22","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.3390\/cancers12071985","article-title":"Anti-cancer potential of cannabinoids, terpenes, and flavonoids present in cannabis","volume":"12","author":"Tomko","year":"2020","journal-title":"Cancers"},{"year":"2015","series-title":"Medical marijuana & your pet. The definitive guide","author":"Silver","key":"10.1016\/j.cvsm.2025.06.017_bib23"},{"issue":"2","key":"10.1016\/j.cvsm.2025.06.017_bib24","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1097\/SPC.0000000000000493","article-title":"Cannabis and cannabinoids in cancer pain management","volume":"14","author":"Meng","year":"2020","journal-title":"Curr Opin Support Palliat Care"},{"key":"10.1016\/j.cvsm.2025.06.017_bib25","article-title":"Medical cannabis or cannabinoids for chronic non-cancer and cancer related pain: a systematic review and meta-analysis of randomised clinical trials","volume":"374","author":"Wang","year":"2021","journal-title":"BMJ Clin Res Ed"},{"issue":"4","key":"10.1016\/j.cvsm.2025.06.017_bib26","first-page":"202","article-title":"MASCC guideline: cannabis for cancer-related pain and risk of harms and adverse events","volume":"31","author":"To","year":"2023","journal-title":"Support Care Cancer"},{"issue":"1","key":"10.1016\/j.cvsm.2025.06.017_bib27","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2022-068182","article-title":"Cannabis for medical use versus opioids for chronic non-cancer pain: a systematic review and network meta-analysis of randomised clinical trials","volume":"14","author":"Jeddi","year":"2024","journal-title":"BMJ Open"},{"issue":"6","key":"10.1016\/j.cvsm.2025.06.017_bib28","first-page":"CD014915","article-title":"Cannabis-based medicines and medical cannabis for adults with cancer pain","volume":"6","author":"H\u00e4user","year":"2023","journal-title":"Cochrane Database Syst Rev"},{"issue":"11","key":"10.1016\/j.cvsm.2025.06.017_bib29","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1016\/j.annonc.2020.07.020","article-title":"Oral THC:CBD cannabis extract for refractory chemotherapy-induced nausea and vomiting: a randomised, placebo-controlled, phase II crossover trial","volume":"31","author":"Grimison","year":"2020","journal-title":"Ann Oncol"},{"issue":"8","key":"10.1016\/j.cvsm.2025.06.017_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.jnha.2024.100299","article-title":"The potential of cannabinoids in managing cancer-related anorexia in older adults: a systematic review of the literature","volume":"28","author":"Ceolin","year":"2024","journal-title":"J Nutr Health Aging"},{"issue":"2","key":"10.1016\/j.cvsm.2025.06.017_bib31","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/vco.12669","article-title":"The effect of cannabidiol on canine neoplastic cell proliferation and mitogen-activated protein kinase activation during autophagy and apoptosis","volume":"19","author":"Henry","year":"2021","journal-title":"Vet Comp Oncol"},{"issue":"3","key":"10.1016\/j.cvsm.2025.06.017_bib32","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1097\/HNP.0000000000000261","article-title":"Frankincense essential oil as a supportive therapy for cancer-related fatigue: a case study","volume":"32","author":"Reis","year":"2018","journal-title":"Holist Nurs Pract"},{"issue":"3","key":"10.1016\/j.cvsm.2025.06.017_bib33","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.ctim.2015.03.009","article-title":"Effects of inhaled ginger aromatherapy on chemotherapy-induced nausea and vomiting and health-related quality of life in women with breast cancer","volume":"23","author":"Lua","year":"2015","journal-title":"Complement Ther Med"},{"issue":"2","key":"10.1016\/j.cvsm.2025.06.017_bib34","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1188\/18.CJON.203-210","article-title":"Aromatherapy: the effect of lavender on anxiety and sleep quality in patients treated with chemotherapy","volume":"22","author":"Ozkaraman","year":"2018","journal-title":"Clin J Oncol Nurs"},{"issue":"1","key":"10.1016\/j.cvsm.2025.06.017_bib35","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1186\/s12906-022-03668-0","article-title":"Aromatherapy with single essential oils can significantly improve the sleep quality of cancer patients: a meta-analysis","volume":"22","author":"Cheng","year":"2022","journal-title":"BMC Complement Med Ther"},{"issue":"4","key":"10.1016\/j.cvsm.2025.06.017_bib36","doi-asserted-by":"crossref","first-page":"503","DOI":"10.4314\/ajtcam.v9i4.7","article-title":"Aromatherapy as an adjuvant treatment in cancer care- a descriptive systematic review","volume":"9","author":"Boehm","year":"2012","journal-title":"Afr J Tradit Complement Altern Med"},{"issue":"3","key":"10.1016\/j.cvsm.2025.06.017_bib37","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD002287.pub2","article-title":"Aromatherapy and massage for symptom relief in patients with cancer","author":"Fellowes","year":"2004","journal-title":"Cochrane Database Syst Rev"},{"issue":"6","key":"10.1016\/j.cvsm.2025.06.017_bib38","first-page":"1518","article-title":"Essential oil of cinnamon exerts anti-cancer activity against head and neck squamous cell carcinoma via attenuating epidermal growth factor receptor-tyrosine kinase","volume":"20","author":"Yang","year":"2015","journal-title":"JBUON"},{"key":"10.1016\/j.cvsm.2025.06.017_bib39","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1186\/1472-6882-11-129","article-title":"Boswellia sacra essential oil induces tumor cell-specific apoptosis and suppresses tumor aggressiveness in cultured human breast cancer cells","volume":"11","author":"Suhail","year":"2011","journal-title":"BMC Complement Altern Med"},{"issue":"3","key":"10.1016\/j.cvsm.2025.06.017_bib40","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0214594","article-title":"Essential oil of Cyphostemma juttae (Vitaceae): chemical composition and antitumor mechanism in triple negative breast cancer cells","volume":"14","author":"Zito","year":"2019","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.cvsm.2025.06.017_bib41","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0231437","article-title":"Croton tiglium essential oil compounds have anti-proliferative and pro-apoptotoic effects in A549 lung cancer cell lines","volume":"15","author":"Niu","year":"2020","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.cvsm.2025.06.017_bib42","doi-asserted-by":"crossref","DOI":"10.1002\/cbdv.202000309","article-title":"Antiproliferative effect and cell cycle alterations induced by salvia officinalis essential oil and its three main components in human colon cancer cell lines","volume":"17","author":"Luca","year":"2020","journal-title":"Chem Biodivers"},{"issue":"1","key":"10.1016\/j.cvsm.2025.06.017_bib43","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1186\/s12906-024-04525-y","article-title":"Navel orange peel essential oil inhibits the growth and progression of triple negative breast cancer","volume":"24","author":"Yang","year":"2024","journal-title":"BMC Complement Med Ther"},{"issue":"15","key":"10.1016\/j.cvsm.2025.06.017_bib44","doi-asserted-by":"crossref","first-page":"4834","DOI":"10.3390\/molecules27154834","article-title":"Pinus mugo essential oil impairs STAT3 activation through oxidative stress and induces apoptosis in prostate cancer cells","volume":"27","author":"Thalappil","year":"2022","journal-title":"Molecules"},{"issue":"13","key":"10.1016\/j.cvsm.2025.06.017_bib45","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1111\/jcmm.17801","article-title":"Elemi essential oil nanocapsulated drug ameliorates lung cancer via oxidative stress, apoptosis and inflammation pathway","volume":"27","author":"Kurban","year":"2023","journal-title":"J Cell Mol Med"},{"key":"10.1016\/j.cvsm.2025.06.017_bib46","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.cbi.2010.07.010","article-title":"The role of reactive oxygen species and oxidative stress in environmental carcinogenesis and biomarker development","volume":"188","author":"Ziech","year":"2010","journal-title":"Chem Biol Interact"},{"issue":"1","key":"10.1016\/j.cvsm.2025.06.017_bib47","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1177\/1534735415610427","article-title":"Efficacy and interaction of antioxidant supplements as adjuvant therapy cancer treatment: a systemic review","volume":"15","author":"Yasueda","year":"2016","journal-title":"Integr Cancer Ther"},{"key":"10.1016\/j.cvsm.2025.06.017_bib48","article-title":"Significance of medicinal mushrooms in integrative oncology: a narrative","volume":"11","author":"Jeitle","year":"2020","journal-title":"Review Front Pharmacol"},{"key":"10.1016\/j.cvsm.2025.06.017_bib49","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/384301","article-title":"Single agent polysaccharopeptide delays metastases and improves survival in naturally occurring hemangiosarcoma","volume":"2012","author":"Brown","year":"2012","journal-title":"Evid Based Complement Alternat Med"},{"issue":"4","key":"10.1016\/j.cvsm.2025.06.017_bib50","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1615\/IntJMedMushrooms.v19.i4.10","article-title":"Medicinal mushrooms in human clinical studies. part I. anticancer, oncoimmunological, and immunomodulatory activities: a review","volume":"19","author":"Wasser","year":"2017","journal-title":"Int J Med Mushrooms"},{"key":"10.1016\/j.cvsm.2025.06.017_bib51","doi-asserted-by":"crossref","DOI":"10.1155\/2024\/7944378","article-title":"Synergistic cytotoxicity of extracts of chaga mushroom and microalgae against mammalian cancer cells in vitro","volume":"2024","author":"Wagle","year":"2024","journal-title":"Oxid Med Cell Longev"},{"key":"10.1016\/j.cvsm.2025.06.017_bib52","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.semcancer.2019.05.006","article-title":"Association of autoimmunity and cancer: an emphasis on proteolytic enzymes","volume":"64","author":"Tabrez","year":"2020","journal-title":"Semin Cancer Biol"},{"issue":"10","key":"10.1016\/j.cvsm.2025.06.017_bib53","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1093\/annonc\/mdu106","article-title":"The efficacy and safety of probiotics in people with cancer: a systematic review","volume":"25","author":"Redman","year":"2014","journal-title":"Ann Oncol"},{"issue":"2","key":"10.1016\/j.cvsm.2025.06.017_bib54","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/nri.2018.4","article-title":"Cancer immunotherapy in 2017: the breakthrough of the microbiota","volume":"18","author":"Kroemer","year":"2018","journal-title":"Nat Rev Immunol"},{"issue":"9","key":"10.1016\/j.cvsm.2025.06.017_bib55","doi-asserted-by":"crossref","first-page":"497","DOI":"10.2217\/fon-2019-0783","article-title":"Gut microbiota and cancer immunotherapy: prognostic and therapeutic implications","volume":"16","author":"Guven","year":"2020","journal-title":"Future Oncol"},{"issue":"6","key":"10.1016\/j.cvsm.2025.06.017_bib56","first-page":"1798","article-title":"Vitamin D-induced molecular mechanisms to potentiate cancer therapy and to reverse drug-resistance","volume":"12","author":"Negri","year":"2020","journal-title":"Cancer Cells Nutrients"},{"issue":"8","key":"10.1016\/j.cvsm.2025.06.017_bib57","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.2174\/18715206113139990319","article-title":"Omega-3 polyunsaturated fatty acids and cancer","volume":"13","author":"Jing","year":"2013","journal-title":"Anticancer Agents Med Chem"},{"issue":"16","key":"10.1016\/j.cvsm.2025.06.017_bib58","doi-asserted-by":"crossref","first-page":"3774","DOI":"10.1002\/cncr.25933","article-title":"Supplementation with fish oil increased first-line chemotherapy efficacy in patients with advanced nonsmall lung cancer","volume":"117","author":"Murphy","year":"2011","journal-title":"Cancer"},{"issue":"3","key":"10.1016\/j.cvsm.2025.06.017_bib59","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1001\/jamaoncol.2015.0388","article-title":"Increased plasma levels of chemoresistance-inducing fatty acid 16:4(n-3) after consumption of fish and fish Oil","volume":"1","author":"Daenen","year":"2015","journal-title":"JAMA Oncol"},{"issue":"16","key":"10.1016\/j.cvsm.2025.06.017_bib60","doi-asserted-by":"crossref","DOI":"10.3390\/ijms241612587","article-title":"An overview of the enhanced effects of curcumin and chemotherapeutic agents in combined cancer treatments","volume":"24","author":"Cacciola","year":"2023","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.cvsm.2025.06.017_bib61","doi-asserted-by":"crossref","DOI":"10.1016\/j.canlet.2023.216332","article-title":"Curcumin in cancer therapy: exploring molecular mechanisms and overcoming clinical challenges","volume":"570","author":"Wang","year":"2023","journal-title":"Cancer Lett"},{"issue":"14","key":"10.1016\/j.cvsm.2025.06.017_bib62","doi-asserted-by":"crossref","first-page":"4491","DOI":"10.1158\/1078-0432.CCR-08-0024","article-title":"Phase II trial of curcumin in patients with advanced pancreatic cancer","volume":"14","author":"Dhillon","year":"2008","journal-title":"Clin Cancer Res"},{"issue":"5","key":"10.1016\/j.cvsm.2025.06.017_bib63","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1080\/1745039X.2020.1769442","article-title":"Dog food production using curcumin as antioxidant: effects of intake on animal growth, health and feed conservation","volume":"74","author":"Campigotto","year":"2020","journal-title":"Arch Anim Nutr"},{"issue":"4","key":"10.1016\/j.cvsm.2025.06.017_bib64","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1055\/s-2006-957450","article-title":"Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers","volume":"64","author":"Shoba","year":"1998","journal-title":"Planta Med"},{"issue":"8","key":"10.1016\/j.cvsm.2025.06.017_bib65","doi-asserted-by":"crossref","first-page":"4380","DOI":"10.3390\/ijms23084380","article-title":"The result of vitamin C treatment of patients with cancer: conditions influencing the effectiveness","volume":"23","author":"Hunyady","year":"2022","journal-title":"Int J Mol Sci"}],"container-title":["Veterinary Clinics of North America: Small Animal Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0195561625000919?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0195561625000919?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T13:24:27Z","timestamp":1762262667000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0195561625000919"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":67,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["S0195561625000919"],"URL":"https:\/\/doi.org\/10.1016\/j.cvsm.2025.06.017","relation":{},"ISSN":["0195-5616"],"issn-type":[{"type":"print","value":"0195-5616"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Integrative Veterinary Oncology","name":"articletitle","label":"Article Title"},{"value":"Veterinary Clinics of North America: Small Animal Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cvsm.2025.06.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}