{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,12]],"date-time":"2023-05-12T02:40:24Z","timestamp":1683859224540},"reference-count":66,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2007,4,1]],"date-time":"2007-04-01T00:00:00Z","timestamp":1175385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cytokine"],"published-print":{"date-parts":[[2007,4]]},"DOI":"10.1016\/j.cyto.2007.04.007","type":"journal-article","created":{"date-parts":[[2007,5,30]],"date-time":"2007-05-30T11:58:18Z","timestamp":1180526298000},"page":"22-31","source":"Crossref","is-referenced-by-count":1,"title":["FGF2 effects in periosteal fibroblasts bearing the FGFR2 receptor Pro253 Arg mutation"],"prefix":"10.1016","volume":"38","author":[{"given":"Cinzia","family":"Lilli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catia","family":"Bellucci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiziano","family":"Baroni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Aisa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Carinci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Scapoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Carinci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Furio","family":"Pezzetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleonora","family":"Lumare","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giordano","family":"Stabellini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Bodo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cyto.2007.04.007_bib1","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1002\/1097-0177(2000)9999:9999<::AID-DVDY1073>3.0.CO;2-F","article-title":"Cranial sutures as intramembranous bone growth sites","volume":"219","author":"Opperman","year":"2000","journal-title":"Dev Dyn"},{"key":"10.1016\/j.cyto.2007.04.007_bib2","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1002\/ajmg.10982","volume":"115","author":"Cohen","year":"2002","journal-title":"Am J Med Genet"},{"issue":"7","key":"10.1016\/j.cyto.2007.04.007_bib3","doi-asserted-by":"crossref","first-page":"1899","DOI":"10.1097\/01.PRS.0000122202.26792.BF","article-title":"Molecular analysis of patients with synostotic frontal plagiocephaly (unilateral coronal synostosis)","volume":"113","author":"Mulliken","year":"2004","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.cyto.2007.04.007_bib4","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1097\/01.PRS.0000146703.08958.95","article-title":"Understanding the molecular basis of Apert syndrome","volume":"115","author":"Ibrahimi","year":"2005","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.cyto.2007.04.007_bib5","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/s004410051374","article-title":"Differential in vitro phenotype pattern, transforming growth factor-beta (1) activity and mRNA expression of transforming growth factor-beta (1) in Apert osteoblasts","volume":"279","author":"Locci","year":"1999","journal-title":"Cell Tissue Res"},{"issue":"4","key":"10.1016\/j.cyto.2007.04.007_bib6","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1359\/jbmr.2003.18.4.751","article-title":"Fibroblast growth factors lead to increased Msx2 expression and fusion in calvarial sutures","volume":"18","author":"Ignelzi","year":"2003","journal-title":"J Bone Miner Res"},{"issue":"6","key":"10.1016\/j.cyto.2007.04.007_bib7","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1097\/01.PRS.0000117362.33347.43","article-title":"TGF-beta1, FGF-2, and receptor mRNA expression in suture mesenchyme and dura versus underlying brain in fusing and nonfusing mouse cranial sutures","volume":"113","author":"Gosain","year":"2004","journal-title":"Plast Reconstr Surg"},{"issue":"4","key":"10.1016\/j.cyto.2007.04.007_bib8","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1597\/02-140.1","article-title":"Transforming growth factor-beta isoform expression in the perisutural tissues of craniosynostotic rabbits","volume":"41","author":"Poisson","year":"2004","journal-title":"Cleft Palate Craniofac J"},{"key":"10.1016\/j.cyto.2007.04.007_bib9","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1006\/cyto.1996.0103","article-title":"Effect of interleukins on Crouzon fibroblast phenotype in vitro. Release of cytokines and IL-6 mRNA expression","volume":"8","author":"Bodo","year":"1996","journal-title":"Cytokine"},{"key":"10.1016\/j.cyto.2007.04.007_bib10","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1046\/j.1365-2362.1997.660618.x","article-title":"Apert\u2019s syndrome: differential in vitro production of matrix macromolecules and its regulation by interleukins","volume":"27","author":"Bodo","year":"1997","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.cyto.2007.04.007_bib11","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S0171-9335(98)80072-1","article-title":"Interleukin pattern of Apert fibroblasts in vitro","volume":"75","author":"Bodo","year":"1998","journal-title":"Eur J Cell Biol"},{"key":"10.1016\/j.cyto.2007.04.007_bib12","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1006\/cyto.1999.0730","article-title":"Interleukin secretion, proteoglycans and procollagen-1(I) gene expression in Crouzon fibroblasts treated with basic fibroblast growth factor","volume":"12","author":"Bodo","year":"2000","journal-title":"Cytokine"},{"key":"10.1016\/j.cyto.2007.04.007_bib13","first-page":"715","article-title":"Role of the extracellular matrix and growth factors in skull morphogenesis and in the pathogenesis of craniosynostosis","volume":"44","author":"Carinci","year":"2000","journal-title":"Int J Dev Biol"},{"issue":"2","key":"10.1016\/j.cyto.2007.04.007_bib14","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1002\/jcp.20148","article-title":"P253R fibroblast growth factor receptor-2 mutation induces RUNX2 transcript variants and calvarial osteoblast differentiation","volume":"202","author":"Baroni","year":"2005","journal-title":"J Cell Physiol"},{"key":"10.1016\/j.cyto.2007.04.007_bib15","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S0171-9335(99)80066-1","article-title":"A regulatory role of fibroblast growth factor in the expression of decorin, biglycan, betaglycan and syndecan in osteoblasts from patients with Crouzon\u2019s syndrome","volume":"78","author":"Bodo","year":"1999","journal-title":"Eur J Cell Biol"},{"key":"10.1016\/j.cyto.2007.04.007_bib16","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1089\/10799900260100105","article-title":"Basic fibroblast growth factor: effects on matrix remodeling, receptor expression, and transduction pathway in human periosteal fibroblasts with FGFR2 gene mutation","volume":"22","author":"Bodo","year":"2002","journal-title":"J Interferon Cytokine Res"},{"key":"10.1016\/j.cyto.2007.04.007_bib17","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1007\/BF03402174","article-title":"Expression profiles of craniosynostosis-derived fibroblasts","volume":"8","author":"Carinci","year":"2002","journal-title":"Mol Med"},{"key":"10.1016\/j.cyto.2007.04.007_bib18","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1006\/cyto.2002.0877","article-title":"Crouzon\u2019s syndrome: differential in vitro secretion of bFGF, TGFbeta I isoforms and extracellular matrix macromolecules in patients with FGFR2 gene mutation","volume":"19","author":"Baroni","year":"2002","journal-title":"Cytokine"},{"key":"10.1016\/j.cyto.2007.04.007_bib19","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/S0168-9525(00)89088-5","article-title":"Fibroblast-growth-factor receptor mutations in human skeletal disorders","volume":"11","author":"Muenke","year":"1995","journal-title":"Trends Genet"},{"key":"10.1016\/j.cyto.2007.04.007_bib20","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S1010-5182(97)80048-0","article-title":"Fibroblast growth factor, their receptors and receptor disorders","volume":"25","author":"Gorlin","year":"1997","journal-title":"J Craniomaxillofac Surg"},{"key":"10.1016\/j.cyto.2007.04.007_bib21","doi-asserted-by":"crossref","first-page":"781","DOI":"10.2741\/A321","article-title":"FGF signaling in skeletal development","volume":"3","author":"Naski","year":"1998","journal-title":"Front Biosci"},{"key":"10.1016\/j.cyto.2007.04.007_bib22","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1359\/jbmr.1998.13.4.645","article-title":"The effects of fibroblast growth factor-2 on human neonatal calvaria osteoblastic cells are differentiation stage specific","volume":"13","author":"Debiais","year":"1998","journal-title":"J Bone Miner Res"},{"issue":"6","key":"10.1016\/j.cyto.2007.04.007_bib23","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1083\/jcb.149.6.1297","article-title":"Signaling by fibroblast growth factors (FGF) and fibroblast growth factor receptor 2 (FGFR2)-activating mutations blocks mineralization and induces apoptosis in osteoblasts","volume":"149","author":"Mansukhani","year":"2000","journal-title":"J Cell Biol"},{"key":"10.1016\/j.cyto.2007.04.007_bib24","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1597\/1545-1569(2002)039<0487:FGFIIC>2.0.CO;2","article-title":"Fibroblast growth factor 2 induces increased calvarial osteoblast proliferation and cranial suture fusion","volume":"39","author":"Moursi","year":"2002","journal-title":"J Cleft Palate Craniofac"},{"key":"10.1016\/j.cyto.2007.04.007_bib25","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.2741\/1671","article-title":"Roles of FGF signaling in skeletal development and human genetic diseases","volume":"10","author":"Chen","year":"2005","journal-title":"Front Biosci"},{"issue":"2","key":"10.1016\/j.cyto.2007.04.007_bib26","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1086\/427956","article-title":"Mutations that cause osteoglophonic dysplasia define novel roles for FGFR1 in bone elongation","volume":"76","author":"White","year":"2005","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.cyto.2007.04.007_bib27","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.cytogfr.2005.03.001","article-title":"Bad bones, absent smell, selfish testes: the pleiotropic consequences of human FGF receptor mutations","volume":"16","author":"Wilkie","year":"2005","journal-title":"Cytokine Growth Factor Rev"},{"key":"10.1016\/j.cyto.2007.04.007_bib28","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1128\/MCB.14.1.181","article-title":"Fibroblast growth factor receptors have different signaling and mitogenic potentials","volume":"14","author":"Wang","year":"1994","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.cyto.2007.04.007_bib29","doi-asserted-by":"crossref","first-page":"3305","DOI":"10.1073\/pnas.89.8.3305","article-title":"Characterization of the murine BEK fibroblast growth factor (FGF) receptor: activation by three members of the FGF family and requirement for heparin","volume":"89","author":"Mansukhani","year":"1992","journal-title":"Proc Natl Acad USA"},{"issue":"2","key":"10.1016\/j.cyto.2007.04.007_bib30","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1002\/(SICI)1521-1878(200002)22:2<108::AID-BIES2>3.0.CO;2-M","article-title":"FGFs, heparan sulfate and FGFRs: complex interactions essential for development","volume":"22","author":"Ornitz","year":"2000","journal-title":"Bioessays"},{"issue":"5103","key":"10.1016\/j.cyto.2007.04.007_bib31","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1126\/science.8456318","article-title":"An essential heparin-binding domain in the fibroblast growth factor receptor kinase","volume":"259","author":"Kan","year":"1993","journal-title":"Science"},{"key":"10.1016\/j.cyto.2007.04.007_bib32","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1002\/0470846658.ch8","article-title":"Genetic control of the cell proliferation-differentiation balance in the developing skull vault: roles of fibroblast growth factor receptor signalling pathways","volume":"232","author":"Morriss-Kay","year":"2001","journal-title":"Novartis Found Sym"},{"key":"10.1016\/j.cyto.2007.04.007_bib33","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1002\/bdrc.10025","article-title":"Roles of FGF receptors in mammalian development and congenital diseases","volume":"69","author":"Coumoul","year":"2003","journal-title":"Birth Defects Res"},{"key":"10.1016\/j.cyto.2007.04.007_bib34","doi-asserted-by":"crossref","first-page":"3063","DOI":"10.1242\/dev.00491","article-title":"Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth","volume":"130","author":"Yu","year":"2003","journal-title":"Development"},{"issue":"34","key":"10.1016\/j.cyto.2007.04.007_bib35","doi-asserted-by":"crossref","first-page":"12555","DOI":"10.1073\/pnas.0405031101","article-title":"A gain-of-function mutation of FGFR2 demonstrates the roles of this receptor variant in osteogenesis","volume":"101","author":"Eswarakumar","year":"2004","journal-title":"Proc Natl Acad USA"},{"issue":"5","key":"10.1016\/j.cyto.2007.04.007_bib36","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1002\/ajmg.1320420505","article-title":"Birth prevalence study of the Apert syndrome","volume":"42","author":"Cohen","year":"1992","journal-title":"Am J Med Genet"},{"issue":"44","key":"10.1016\/j.cyto.2007.04.007_bib37","doi-asserted-by":"crossref","first-page":"45926","DOI":"10.1074\/jbc.M404824200","article-title":"A soluble form of fibroblast growth factor receptor 2 (FGFR2) wth S252W mutation acts as an efficient inhibitor for the enhanced osteoblastic differentiation caused by FGFR2 activation in Apert syndrome","volume":"279","author":"Tanimoto","year":"2004","journal-title":"J Biol Chem"},{"issue":"1","key":"10.1016\/j.cyto.2007.04.007_bib38","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1080\/03008200390181799","article-title":"Activating (P253R, C278F) and dominant negative mutation of FGFR2: differential effects on calvarial bone cell proliferation, differentiation, and mineralization","volume":"44","author":"Ratisoontorn","year":"2003","journal-title":"Connect Tissue Res"},{"issue":"5","key":"10.1016\/j.cyto.2007.04.007_bib39","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1359\/jbmr.2001.16.5.832","article-title":"Role of N-cadherin and protein kinase C in osteoblast gene activation induced by the S252W fibroblast growth factor receptor 2 mutation in Apert craniosynostosis","volume":"16","author":"Lemmonier","year":"2001","journal-title":"J Bone Miner Res"},{"issue":"5","key":"10.1016\/j.cyto.2007.04.007_bib40","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1016\/S0002-9440(10)64139-9","article-title":"Increased osteoblast apoptosis in Apert craniosynostosis: role of protein kinase C and interleukin-1","volume":"158","author":"Lemmonier","year":"2001","journal-title":"Am J Pathol"},{"issue":"5","key":"10.1016\/j.cyto.2007.04.007_bib41","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1016\/S0002-9440(10)65401-6","article-title":"Decreased proliferation and altered differentiation in osteoblasts from genetically an clinically distinct craniosynostotic disorders","volume":"154","author":"Fragale","year":"1999","journal-title":"Am J Pathol"},{"key":"10.1016\/j.cyto.2007.04.007_bib42","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1007\/s003810050457","article-title":"Craniosynostosis: from a clinical description to an understanding of bone formation of the skull","volume":"15","author":"Lajeunie","year":"1999","journal-title":"Childs Nerv Syst"},{"key":"10.1016\/j.cyto.2007.04.007_bib43","doi-asserted-by":"crossref","first-page":"6861","DOI":"10.1016\/S0021-9258(17)39929-5","article-title":"Differences in glycosaminoglycans synthesized by fibroblast-like cells from chick cornea, heart, and skin","volume":"252","author":"Conrad","year":"1977","journal-title":"J Biol Chem"},{"key":"10.1016\/j.cyto.2007.04.007_bib44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/ijc.2910200102","article-title":"Binding of soluble form of fibroblast surface protein, fibronectin, to collagen","volume":"20","author":"Engvall","year":"1977","journal-title":"Int J Cancer"},{"key":"10.1016\/j.cyto.2007.04.007_bib45","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1016\/S0006-291X(76)80180-5","article-title":"The estimation of two collagens from human dermis by interrupted gel electrophoresis","volume":"72","author":"Sykes","year":"1976","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.cyto.2007.04.007_bib46","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0014-5793(92)80300-6","article-title":"A novel coumarin-labelled peptide for sensitive continuous assay of the matrix metalloproteinases","volume":"296","author":"Knight","year":"1992","journal-title":"FEBS Lett"},{"key":"10.1016\/j.cyto.2007.04.007_bib47","doi-asserted-by":"crossref","first-page":"21491","DOI":"10.1074\/jbc.274.31.21491","article-title":"Matrix metalloproteinases","volume":"274","author":"Nagase","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1016\/j.cyto.2007.04.007_bib48","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0304-4165(03)00054-0","article-title":"Cathepsin B in osteoblasts","volume":"1621","author":"Aisa","year":"2003","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.cyto.2007.04.007_bib49","doi-asserted-by":"crossref","first-page":"5346","DOI":"10.1073\/pnas.87.14.5346","article-title":"Autocrine transformation by a chimeric signal-peptide-basic fibroblast growth factor: reversal by suramin","volume":"87","author":"Yayon","year":"1990","journal-title":"Proc Natl Acad Sci USA"},{"issue":"4","key":"10.1016\/j.cyto.2007.04.007_bib50","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/0092-8674(91)90512-W","article-title":"Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor","volume":"64","author":"Yayon","year":"1991","journal-title":"Cell"},{"key":"10.1016\/j.cyto.2007.04.007_bib51","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1111\/j.1749-6632.1949.tb27297.x","article-title":"The attractions of proteins for small molecules and ions","volume":"51","author":"Scatchard","year":"1949","journal-title":"Ann NY Acad Sci"},{"issue":"12","key":"10.1016\/j.cyto.2007.04.007_bib52","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1101\/gad.990702","article-title":"FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease","volume":"16","author":"Ornitz","year":"2002","journal-title":"Genes Dev"},{"issue":"2","key":"10.1016\/j.cyto.2007.04.007_bib53","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/s00441-004-0966-7","article-title":"Hyaluronidase expression in cultured growth plate chondrocytes during differentiation","volume":"318","author":"Tanimoto","year":"2004","journal-title":"Cell Tissue Res"},{"issue":"3","key":"10.1016\/j.cyto.2007.04.007_bib54","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1097\/01.SCS.0000157078.53871.11","article-title":"Apert and Crouzon Syndromes: clinical findings, genes and extracellular matrix","volume":"16","author":"Carinci","year":"2005","journal-title":"J Craniofac Surg"},{"key":"10.1016\/j.cyto.2007.04.007_bib55","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1002\/ajmg.1320570119","article-title":"Hands and feet in the Apert syndrome","volume":"57","author":"Cohen","year":"1995","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.cyto.2007.04.007_bib56","series-title":"Craniosynostosys, diagnosis, evaluation, and management","first-page":"316","article-title":"Apert syndrome","author":"Cohen","year":"2000"},{"issue":"2","key":"10.1016\/j.cyto.2007.04.007_bib57","first-page":"94","article-title":"Merging the old skeletal biology with the new. II. Molecular aspects of bone formation and bone growth","volume":"20","author":"Cohen","year":"2000","journal-title":"J Craniofac Genet Dev Biol"},{"key":"10.1016\/j.cyto.2007.04.007_bib58","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1034\/j.1399-0004.2000.570208.x","article-title":"Genotype\u2013phenotype analysisi in Apert syndrome suggests opposite effects of the two recurrent mutations on syndactyly and outcome of craniofacial surgery","volume":"57","author":"Von Gernet","year":"2000","journal-title":"Clin Genet"},{"key":"10.1016\/j.cyto.2007.04.007_bib59","doi-asserted-by":"crossref","first-page":"2776","DOI":"10.1074\/jbc.270.6.2776","article-title":"Interaction of biglycan with type I collagen","volume":"270","author":"Schonherr","year":"1995","journal-title":"J Biol Chem"},{"key":"10.1016\/j.cyto.2007.04.007_bib60","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1002\/(SICI)1097-0215(19960328)66:1<82::AID-IJC15>3.0.CO;2-D","article-title":"Stimulation of gelatinase B and tissue inhibitors of metalloproteinase (TIMP) production in co-culture of human osteosarcoma cells and human fibroblasts: gelatinase B production was stimulated via up-regulation of fibroblast growth factor (FGF) receptor","volume":"66","author":"Kurogi","year":"1996","journal-title":"Int J Cancer"},{"key":"10.1016\/j.cyto.2007.04.007_bib61","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1093\/hmg\/7.9.1475","article-title":"Apert syndrome mutations in fibroblast growth factor receptor 2 exhibit increased affinity for FGF ligand","volume":"7","author":"Anderson","year":"1998","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.cyto.2007.04.007_bib62","doi-asserted-by":"crossref","first-page":"14536","DOI":"10.1073\/pnas.97.26.14536","article-title":"Loss of fibroblast growth factor receptor 2 ligand binding specificity in Apert syndrome","volume":"97","author":"Yu","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"issue":"9","key":"10.1016\/j.cyto.2007.04.007_bib63","doi-asserted-by":"crossref","first-page":"5927","DOI":"10.1016\/S0021-9258(18)42643-9","article-title":"Binding of two growth factor families to separate domains of the proteoglycan betaglycan","volume":"267","author":"Andres","year":"1992","journal-title":"J Biol Chem"},{"issue":"13","key":"10.1016\/j.cyto.2007.04.007_bib64","doi-asserted-by":"crossref","first-page":"7182","DOI":"10.1073\/pnas.121183798","article-title":"Structural basis for fibroblast growth factor receptor 2 actvation in Apert syndrome","volume":"98","author":"Ibrahimi","year":"2001","journal-title":"Proc Natl Acad USA"},{"key":"10.1016\/j.cyto.2007.04.007_bib65","doi-asserted-by":"crossref","first-page":"26037","DOI":"10.1074\/jbc.270.44.26037","article-title":"Constitutive activation of fibroblast growth factor receptor-2 by a point mutation associated with Crouzon syndrome","volume":"270","author":"Neilson","year":"1995","journal-title":"J Biol Chem"},{"issue":"1","key":"10.1016\/j.cyto.2007.04.007_bib66","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1002\/(SICI)1097-4652(199707)172:1<117::AID-JCP13>3.0.CO;2-9","article-title":"Mutation associated with Crouzon syndrome causes ligand-independent dimerization and activation of FGF receptor-2","volume":"172","author":"Mangasarian","year":"1997","journal-title":"J Cell Physiol"}],"container-title":["Cytokine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043466607000865?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043466607000865?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,12]],"date-time":"2023-05-12T02:26:00Z","timestamp":1683858360000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1043466607000865"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4]]},"references-count":66,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,4]]}},"alternative-id":["S1043466607000865"],"URL":"https:\/\/doi.org\/10.1016\/j.cyto.2007.04.007","relation":{},"ISSN":["1043-4666"],"issn-type":[{"value":"1043-4666","type":"print"}],"subject":[],"published":{"date-parts":[[2007,4]]}}}