{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:56:43Z","timestamp":1787237803596,"version":"build-2736575974"},"reference-count":24,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cytokine"],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1016\/j.cyto.2011.12.010","type":"journal-article","created":{"date-parts":[[2012,1,10]],"date-time":"2012-01-10T17:57:14Z","timestamp":1326218234000},"page":"6-9","source":"Crossref","is-referenced-by-count":67,"title":["Increased levels of interleukin-33 associated with bone erosion and interstitial lung diseases in patients with rheumatoid arthritis"],"prefix":"10.1016","volume":"58","author":[{"given":"Zhu","family":"Xiangyang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Lutian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhao","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Liping","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shen","family":"Hui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Jing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.cyto.2011.12.010_b0005","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1136\/ard.54.8.654","article-title":"Detection of cytokine producing cells in the synovial membrane from patients with rheumatoid arthritis","volume":"54","author":"Ulfgren","year":"1995","journal-title":"Ann Rheum Dis"},{"issue":"5","key":"10.1016\/j.cyto.2011.12.010_b0010","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.immuni.2005.09.015","article-title":"IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines","volume":"23","author":"Schmitz","year":"2005","journal-title":"Immunity"},{"issue":"36","key":"10.1016\/j.cyto.2011.12.010_b0125","doi-asserted-by":"crossref","first-page":"26369","DOI":"10.1074\/jbc.M704916200","article-title":"Soluble ST2 blocks interleukin-33 signaling in allergic airway inflammation","volume":"282","author":"Hayakawa","year":"2007","journal-title":"J Biol Chem"},{"issue":"9","key":"10.1016\/j.cyto.2011.12.010_b0020","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1016\/j.cellsig.2008.05.013","article-title":"TRAF6 is a critical signal transducer in IL-33 signaling pathway","volume":"20","author":"Funakoshi-Tago","year":"2008","journal-title":"Cell Signal"},{"issue":"10","key":"10.1016\/j.cyto.2011.12.010_b0025","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1038\/nrd2660","article-title":"The IL-33\/ST2 pathway: therapeutic target and novel biomarker","volume":"7","author":"Kakkar","year":"2008","journal-title":"Nat Rev Drug Discov"},{"issue":"2","key":"10.1016\/j.cyto.2011.12.010_b0030","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1111\/j.1365-2222.2009.03384.x","article-title":"IL-33: a tissue derived cytokine pathway involved in allergic inflammation and asthma","volume":"40","author":"Smith","year":"2010","journal-title":"Clin Exp Allergy"},{"issue":"8","key":"10.1016\/j.cyto.2011.12.010_b0130","doi-asserted-by":"crossref","first-page":"5094","DOI":"10.4049\/jimmunol.0802387","article-title":"Increased expression of IL-33 in severe asthma: evidence of expression by airway smooth muscle cells","volume":"183","author":"Prefontaine","year":"2009","journal-title":"J Immunol"},{"issue":"1","key":"10.1016\/j.cyto.2011.12.010_b0040","doi-asserted-by":"crossref","first-page":"18","DOI":"10.3899\/jrheum.090492","article-title":"Increased levels of interleukin 33 in sera and synovial fluid from patients with active rheumatoid arthritis","volume":"37","author":"Matsuyama","year":"2010","journal-title":"J Rheumatol"},{"issue":"11","key":"10.1016\/j.cyto.2011.12.010_b0045","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1038\/mp.2009.10","article-title":"Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer\u2019s disease","volume":"14","author":"Chapuis","year":"2009","journal-title":"Mol Psychiatry"},{"issue":"2","key":"10.1016\/j.cyto.2011.12.010_b0050","doi-asserted-by":"crossref","first-page":"143","DOI":"10.2332\/allergolint.10-RAI-0186","article-title":"IL-33 and IL-33 receptors in host defense and diseases","volume":"59","author":"Oboki","year":"2010","journal-title":"Allergol Int"},{"issue":"9","key":"10.1016\/j.cyto.2011.12.010_b0055","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1136\/ard.2009.122655","article-title":"IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy","volume":"69","author":"Verri","year":"2010","journal-title":"Ann Rheum Dis"},{"issue":"31","key":"10.1016\/j.cyto.2011.12.010_b0135","doi-asserted-by":"crossref","first-page":"10913","DOI":"10.1073\/pnas.0801898105","article-title":"IL-33 exacerbates antigen-induced arthritis by activating mast cells","volume":"105","author":"Xu","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"3","key":"10.1016\/j.cyto.2011.12.010_b0065","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1002\/art.24305","article-title":"Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis","volume":"60","author":"Palmer","year":"2009","journal-title":"Arthritis Rheum"},{"issue":"1","key":"10.1016\/j.cyto.2011.12.010_b0140","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1073\/pnas.0606854104","article-title":"IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo","volume":"104","author":"Carriere","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"3","key":"10.1016\/j.cyto.2011.12.010_b0075","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/art.1780310302","article-title":"The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis","volume":"31","author":"Arnett","year":"1988","journal-title":"Arthritis Rheum"},{"issue":"1","key":"10.1016\/j.cyto.2011.12.010_b0145","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1002\/art.1780380107","article-title":"Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis","volume":"38","author":"Prevoo","year":"1995","journal-title":"Arthritis Rheum"},{"issue":"3","key":"10.1016\/j.cyto.2011.12.010_b0085","first-page":"743","article-title":"How to read radiographs according to the Sharp\/van der Heijde method","volume":"26","author":"van der Heijde","year":"1999","journal-title":"J Rheumatol"},{"issue":"5","key":"10.1016\/j.cyto.2011.12.010_b0090","doi-asserted-by":"crossref","first-page":"2620","DOI":"10.4049\/jimmunol.0902685","article-title":"IL-33 exacerbates autoantibody-induced arthritis","volume":"184","author":"Xu","year":"2010","journal-title":"J Immunol"},{"issue":"10","key":"10.1016\/j.cyto.2011.12.010_b0095","doi-asserted-by":"crossref","first-page":"2006","DOI":"10.3899\/jrheum.100184","article-title":"Elevated serum interleukin 33 is associated with autoantibody production in patients with rheumatoid arthritis","volume":"37","author":"Mu","year":"2010","journal-title":"J Rheumatol"},{"key":"10.1016\/j.cyto.2011.12.010_b0150","doi-asserted-by":"crossref","DOI":"10.1007\/s00296-011-1854-6","article-title":"Sustained elevation of interleukin-33 in sera and synovial fluids from patients with rheumatoid arthritis non-responsive to anti-tumor necrosis factor: possible association with persistent IL-1beta signaling and a poor clinical response","author":"Matsuyama","year":"2011","journal-title":"Rheumatol Int."},{"issue":"12","key":"10.1016\/j.cyto.2011.12.010_b0155","doi-asserted-by":"crossref","first-page":"7879","DOI":"10.4049\/jimmunol.178.12.7879","article-title":"Coexpression of IL-5 and eotaxin-2 in mice creates an eosinophil-dependent model of respiratory inflammation with characteristics of severe asthma","volume":"178","author":"Ochkur","year":"2007","journal-title":"J Immunol"},{"issue":"8","key":"10.1016\/j.cyto.2011.12.010_b0110","doi-asserted-by":"crossref","first-page":"2827","DOI":"10.1073\/pnas.0700021104","article-title":"Transcription factor T-bet regulates skin sclerosis through its function in innate immunity and via IL-13","volume":"104","author":"Aliprantis","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"10","key":"10.1016\/j.cyto.2011.12.010_b0115","doi-asserted-by":"crossref","first-page":"2779","DOI":"10.1002\/eji.200737547","article-title":"IL-33 is a chemoattractant for human Th2 cells","volume":"37","author":"Komai-Koma","year":"2007","journal-title":"Eur J Immunol"},{"issue":"4","key":"10.1016\/j.cyto.2011.12.010_b0160","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.4049\/jimmunol.179.4.2551","article-title":"IL-1 receptor accessory protein and ST2 comprise the IL-33 receptor complex","volume":"179","author":"Chackerian","year":"2007","journal-title":"J Immunol"}],"container-title":["Cytokine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043466611008623?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043466611008623?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T00:25:40Z","timestamp":1543278340000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1043466611008623"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["S1043466611008623"],"URL":"https:\/\/doi.org\/10.1016\/j.cyto.2011.12.010","relation":{},"ISSN":["1043-4666"],"issn-type":[{"value":"1043-4666","type":"print"}],"subject":[],"published":{"date-parts":[[2012,4]]}}}