{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T13:18:43Z","timestamp":1773753523813,"version":"3.50.1"},"reference-count":31,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cytokine"],"published-print":{"date-parts":[[2015,6]]},"DOI":"10.1016\/j.cyto.2015.02.021","type":"journal-article","created":{"date-parts":[[2015,3,21]],"date-time":"2015-03-21T10:10:12Z","timestamp":1426932612000},"page":"270-276","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"title":["Plasma osteopontin in acute liver failure"],"prefix":"10.1016","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1224-2651","authenticated-orcid":false,"given":"Praveen","family":"Srungaram","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jody A.","family":"Rule","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"He Jun","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Reimold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benny","family":"Dahl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corron","family":"Sanders","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William M.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.cyto.2015.02.021_b0005","doi-asserted-by":"crossref","first-page":"947","DOI":"10.7326\/0003-4819-137-12-200212170-00007","article-title":"Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States","volume":"137","author":"Ostapowicz","year":"2002","journal-title":"Ann Int Med"},{"issue":"5","key":"10.1016\/j.cyto.2015.02.021_b0010","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.jhep.2008.08.009","article-title":"The importance of immune dysfunction in determining outcome in acute liver failure","volume":"49","author":"Antoniades","year":"2008","journal-title":"J Hepatol"},{"issue":"23","key":"10.1016\/j.cyto.2015.02.021_b0015","doi-asserted-by":"crossref","first-page":"8819","DOI":"10.1073\/pnas.83.23.8819","article-title":"Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence","volume":"83","author":"Oldberg","year":"1986","journal-title":"Proc Natl Acad Sci USA"},{"issue":"5","key":"10.1016\/j.cyto.2015.02.021_b0020","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/j.1440-1827.2011.02649.x","article-title":"Osteopontin, intrinsic tissue regulator of intractable inflammatory diseases","volume":"61","author":"Uede","year":"2011","journal-title":"Pathol Int"},{"issue":"4","key":"10.1016\/j.cyto.2015.02.021_b0025","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.immuni.2004.08.012","article-title":"Osteopontin as a mediator of NKT cell function in T cell-mediated liver diseases","volume":"21","author":"Diao","year":"2004","journal-title":"Immunity"},{"issue":"41","key":"10.1016\/j.cyto.2015.02.021_b0030","doi-asserted-by":"crossref","first-page":"15884","DOI":"10.1073\/pnas.0806089105","article-title":"Osteopontin regulates development and function of invariant natural killer T cells","volume":"105","author":"Diao","year":"2008","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.cyto.2015.02.021_b0035","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/s12079-009-0068-0","article-title":"The role of osteopontin in inflammatory processes","volume":"3","author":"Lund","year":"2009","journal-title":"J Cell Commun Signal"},{"issue":"11","key":"10.1016\/j.cyto.2015.02.021_b0040","doi-asserted-by":"crossref","first-page":"2685","DOI":"10.1002\/ijc.26301","article-title":"Prognostic significance of osteopontin in hepatocellular carcinoma: a meta-analysis","volume":"130","author":"Zhang","year":"2012","journal-title":"Int J Cancer"},{"issue":"2","key":"10.1016\/j.cyto.2015.02.021_b0045","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1002\/hep.24703","article-title":"Identification of osteopontin as a novel marker for early hepatocellular carcinoma","volume":"55","author":"Shang","year":"2012","journal-title":"Hepatology"},{"issue":"1\u20133","key":"10.1016\/j.cyto.2015.02.021_b0050","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1007\/s12026-010-8179-5","article-title":"Intracellular osteopontin (iOPN) and immunity","volume":"49","author":"Inoue","year":"2011","journal-title":"Immunol Res"},{"issue":"4","key":"10.1016\/j.cyto.2015.02.021_b0055","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.hepres.2004.03.009","article-title":"Plasma osteopontin levels in patients with fulminant hepatitis","volume":"29","author":"Matsui","year":"2004","journal-title":"Hepatol Res"},{"issue":"1","key":"10.1016\/j.cyto.2015.02.021_b0060","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1080\/00365520510024061","article-title":"Serum osteopontin levels in patients with acute liver dysfunction","volume":"41","author":"Arai","year":"2006","journal-title":"Scand J Gastroenterol"},{"issue":"5","key":"10.1016\/j.cyto.2015.02.021_b0065","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1002\/hep.20703","article-title":"AASLD position paper: the management of acute liver failure","volume":"41","author":"Polson","year":"2005","journal-title":"Hepatology"},{"issue":"7","key":"10.1016\/j.cyto.2015.02.021_b0070","first-page":"1480","article-title":"The association of race and ethnicity with disease expression in male US veterans with rheumatoid arthritis","volume":"34","author":"Mikuls","year":"2007","journal-title":"J Heumatol"},{"issue":"3","key":"10.1016\/j.cyto.2015.02.021_b0075","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0009-9120(96)84728-A","article-title":"Quantification of osteopontin in human plasma with an ELISA: basal levels in pre- and postmenopausal women","volume":"29","author":"Bautista","year":"1996","journal-title":"Clin Biochem"},{"issue":"12","key":"10.1016\/j.cyto.2015.02.021_b9000","first-page":"4060","article-title":"Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate, and lung cancer","volume":"7","author":"Fedarko","year":"2001","journal-title":"Clin Cancer Res"},{"issue":"4","key":"10.1016\/j.cyto.2015.02.021_b0080","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.3892\/or.2013.2666","article-title":"Plasma osteopontin concentrations in patients with cutaneous melanoma","volume":"30","author":"Filia","year":"2013","journal-title":"Oncol Rep"},{"issue":"3","key":"10.1016\/j.cyto.2015.02.021_b0085","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1002\/cncr.10709","article-title":"Plasma osteopontin: association with survival and metastasis to bone in men with hormone-refractory prostate carcinoma","volume":"95","author":"Hotte","year":"2002","journal-title":"Cancer"},{"issue":"3","key":"10.1016\/j.cyto.2015.02.021_b0090","doi-asserted-by":"crossref","first-page":"354","DOI":"10.4103\/0972-124X.100910","article-title":"Estimation and comparison of osteopontin levels in plasma in subjects with healthy periodontium and generalized chronic periodontitis and its assessment after scaling and root planing","volume":"16","author":"Han","year":"2012","journal-title":"J Indian Soc Periodontol"},{"issue":"3","key":"10.1016\/j.cyto.2015.02.021_b0100","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1006\/bbrc.1999.0372","article-title":"Expression of osteopontin in Kupffer cells and hepatic macrophages and Stellate cells in rat liver after carbon tetrachloride intoxication: a possible factor for macrophage migration into hepatic necrotic areas","volume":"256","author":"Kawashima","year":"1999","journal-title":"Biochem Biophys Res Commun"},{"issue":"1","key":"10.1016\/j.cyto.2015.02.021_b0105","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1093\/toxsci\/kfm246","article-title":"Pathophysiological role of osteopontin in hepatic inflammation, toxicity, and cancer","volume":"103","author":"Ramaiah","year":"2008","journal-title":"Toxicol Sci"},{"key":"10.1016\/j.cyto.2015.02.021_b0110","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1002\/hep.21563","article-title":"The model for end-stage liver disease (MELD)","volume":"45","author":"Kamath","year":"2007","journal-title":"Hepatology"},{"issue":"1","key":"10.1016\/j.cyto.2015.02.021_b0115","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.hepres.2005.01.016","article-title":"Increased cytoprotective function in the liver of transgenic mice expressing osteopontin in hepatocytes","volume":"32","author":"Koh","year":"2005","journal-title":"Hepatol Res"},{"issue":"2","key":"10.1016\/j.cyto.2015.02.021_b0120","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.bbrc.2004.03.057","article-title":"Gene expression profiles in liver regeneration with oval cell induction","volume":"317","author":"Arai","year":"2004","journal-title":"Biochem Biophys Res Commun"},{"issue":"4","key":"10.1016\/j.cyto.2015.02.021_b0125","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1002\/hep.24228","article-title":"Hepatic encephalopathy: a central neuroinflammatory disorder?","volume":"53","author":"Butterworth","year":"2011","journal-title":"Hepatology"},{"issue":"4","key":"10.1016\/j.cyto.2015.02.021_b0130","doi-asserted-by":"crossref","first-page":"249","DOI":"10.2174\/187152810793358778","article-title":"The role of osteopontin in experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS)","volume":"9","author":"Braitch","year":"2010","journal-title":"Inflamm Allergy Drug Targets"},{"issue":"4","key":"10.1016\/j.cyto.2015.02.021_b0135","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.3233\/JAD-2010-1309","article-title":"Osteopontin is increased in the cerebrospinal fluid of patients with Alzheimer\u2019s disease and its levels correlate with cognitive decline","volume":"19","author":"Comi","year":"2010","journal-title":"J Alzheimers Dis"},{"issue":"24","key":"10.1016\/j.cyto.2015.02.021_b0140","doi-asserted-by":"crossref","first-page":"18337","DOI":"10.1074\/jbc.M001529200","article-title":"The activation state of alpha v beta 3 regulates platelet and lymphocyte adhesion to intact and thrombin-cleaved osteopontin","volume":"275","author":"Helluin","year":"2000","journal-title":"J Biol Chem"},{"issue":"51","key":"10.1016\/j.cyto.2015.02.021_b0145","doi-asserted-by":"crossref","first-page":"51285","DOI":"10.1074\/jbc.M304581200","article-title":"Quantitative analysis of platelet alpha v beta 3 binding to osteopontin using laser tweezers","volume":"278","author":"Litvinov","year":"2003","journal-title":"J Biol Chem"},{"issue":"3","key":"10.1016\/j.cyto.2015.02.021_b0150","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1053\/jhep.2003.50113","article-title":"Thrombopoietin in acute liver failure","volume":"37","author":"Schiodt","year":"2003","journal-title":"Hepatology"},{"key":"10.1016\/j.cyto.2015.02.021_b0155","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.jhep.2011.04.020","article-title":"Minimal effects of acute liver injury\/acute liver failure on hemeostasis as assessed by thromboelastography","volume":"56","author":"Stravitz","year":"2012","journal-title":"J Hepatol"}],"container-title":["Cytokine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043466615000800?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043466615000800?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,22]],"date-time":"2019-08-22T02:37:04Z","timestamp":1566441424000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1043466615000800"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["S1043466615000800"],"URL":"https:\/\/doi.org\/10.1016\/j.cyto.2015.02.021","relation":{},"ISSN":["1043-4666"],"issn-type":[{"value":"1043-4666","type":"print"}],"subject":[],"published":{"date-parts":[[2015,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Plasma osteopontin in acute liver failure","name":"articletitle","label":"Article Title"},{"value":"Cytokine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cyto.2015.02.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}