{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T22:41:29Z","timestamp":1767912089516,"version":"3.49.0"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001349","name":"National Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]},{"name":"New Investigator Grant"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cytokine"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1016\/j.cyto.2016.05.009","type":"journal-article","created":{"date-parts":[[2016,5,27]],"date-time":"2016-05-27T17:05:08Z","timestamp":1464368708000},"page":"56-62","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Aqueous humor immune factors and cytomegalovirus (CMV) levels in CMV retinitis through treatment \u2013 The CRIGSS study"],"prefix":"10.1016","volume":"84","author":[{"given":"Jayant Venkatramani","family":"Iyer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rupesh","family":"Agrawal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tun Kuan","family":"Yeo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dinesh V.","family":"Gunasekeran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Praveen Kumar","family":"Balne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernett","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veonice Bijin","family":"Au","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Connolly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen C.B.","family":"Teoh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cyto.2016.05.009_b0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.cytogfr.2015.09.001","article-title":"Current topics in HIV-1 pathogenesis: the emergence of deregulated immuno-metabolism in HIV-infected subjects","author":"Dagenais-Lussier","year":"2015","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.cyto.2016.05.009_b0010","doi-asserted-by":"crossref","first-page":"285","DOI":"10.2147\/OPTH.S6700","article-title":"Optimal management of cytomegalovirus retinitis in patients with AIDS","volume":"4","author":"Stewart","year":"2010","journal-title":"Clin Ophthalmol."},{"key":"10.1016\/j.cyto.2016.05.009_b0015","first-page":"623","article-title":"Ocular manifestations of HIV infection","volume":"63","author":"Jabs","year":"1995","journal-title":"Trans. Am. Ophthalmol. Soc."},{"key":"10.1016\/j.cyto.2016.05.009_b0020","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/S0002-9394(14)71453-9","article-title":"Correlation between CD4 counts and prevalence of cytomegalovirus retinitis and human immunodeficiency virus-related noninfectious retinal vasculopathy in patients with acquired immunodeficiency syndrome","volume":"115","author":"Kupperman","year":"1993","journal-title":"Am. J. Ophthalmol."},{"issue":"2","key":"10.1016\/j.cyto.2016.05.009_b0025","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1093\/infdis\/158.2.449","article-title":"Cytomegalovirus infection in patients with AIDS","volume":"158","author":"Drew","year":"1988","journal-title":"J. Infect. Dis."},{"issue":"5","key":"10.1016\/j.cyto.2016.05.009_b0030","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1097\/00000441-199905000-00009","article-title":"Cytomegalovirus infection in the era of highly active antiretroviral therapy (HAART)","volume":"317","author":"Skiest","year":"1999","journal-title":"Am. J. Med. Sci."},{"issue":"2\u20133","key":"10.1016\/j.cyto.2016.05.009_b0035","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1080\/02713680490504641","article-title":"AIDS-related CMV retinitis: lessons from the laboratory","volume":"29","author":"Dix","year":"2004","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.cyto.2016.05.009_b0040","first-page":"7","article-title":"Advances in understanding cytomegalovirus infection after transplantation","volume":"26","author":"Ho","year":"1994","journal-title":"Transpl. Proc."},{"key":"10.1016\/j.cyto.2016.05.009_b0045","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1056\/NEJM199807233390406","article-title":"Ocular manifestations of HIV infection","volume":"339","author":"Cunningham","year":"1998","journal-title":"N. Engl. J. Med."},{"issue":"7","key":"10.1016\/j.cyto.2016.05.009_b0050","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1016\/j.ophtha.2015.02.033","article-title":"Studies of the ocular complications of AIDS research group. Long-term outcomes of CMVR in the era of modern antiretroviral therapy: results from a United States cohort","volume":"122","author":"Jabs","year":"2015","journal-title":"Ophthalmology"},{"issue":"9","key":"10.1016\/j.cyto.2016.05.009_b0055","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1007\/s00417-014-2587-5","article-title":"Outcome of cytomegalovirus retinitis in immunocompromised patients without Human Immunodeficiency virus treated with intravitreal ganciclovir injection","volume":"252","author":"Agarwal","year":"2014","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"issue":"4","key":"10.1016\/j.cyto.2016.05.009_b0060","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1167\/iovs.05-0836","article-title":"Cytokine profile of aqueous humor and sera of patients with infectious or noninfectious uveitis","volume":"47","author":"Takase","year":"2006","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.cyto.2016.05.009_b0065","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1097\/ICU.0b013e32801094b5","article-title":"Inflammatory mediators of uveitis: cytokines and chemokines","volume":"17","author":"Curnow","year":"2006","journal-title":"Curr. Opin. Ophthalmol."},{"issue":"8","key":"10.1016\/j.cyto.2016.05.009_b0070","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1086\/597478","article-title":"Cytokine profiles in toxoplasmic and viral uveitis","volume":"199","author":"Lahmar","year":"2009","journal-title":"J. Infect. Dis."},{"issue":"2","key":"10.1016\/j.cyto.2016.05.009_b0075","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.cyto.2013.08.006","article-title":"Cytokine analysis of aqueous humor in HIV patients with cytomegalovirus retinitis","volume":"64","author":"Iyer","year":"2013","journal-title":"Cytokine"},{"issue":"4","key":"10.1016\/j.cyto.2016.05.009_b0080","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0966-842X(03)00066-0","article-title":"Human cytomegalovirus retinitis: pathogenicity, immune evasion, and persistence","volume":"11","author":"Scholz","year":"2003","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.cyto.2016.05.009_b0085","unstructured":"J. Iyer, R. Agrawal, T.H. Yeo, D.V. Gunasekeran, P.K. Balne, V.B. Au, J. Connolly, S.C. Teoh, Aqueous humor cytokine profiling in HIV patients with cytomegalovirus (CMV) retinitis, Data in brief (submitted for publication)."},{"issue":"5","key":"10.1016\/j.cyto.2016.05.009_b0090","doi-asserted-by":"crossref","first-page":"2026","DOI":"10.1167\/iovs.02-0980","article-title":"Differential expression of chemokines by human retinal pigment epithelial cells infected with cytomegalovirus","volume":"44","author":"Momma","year":"2003","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"7","key":"10.1016\/j.cyto.2016.05.009_b0095","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1089\/jop.2013.0241","article-title":"Continued decline of aqueous interleukin-8 after multiple intravitreal injections of ganciclovir for cytomegalovirus retinitis","volume":"30","author":"Wang","year":"2014","journal-title":"J. Ocul. Pharmacol. Ther."},{"key":"10.1016\/j.cyto.2016.05.009_b0100","doi-asserted-by":"crossref","DOI":"10.1099\/vir.0.000101","article-title":"Stimulatory effects of human cytomegalovirus tegument protein pp71 lead to increased expression of CCL2 (MCP-1) during infection","author":"Naing","year":"2015","journal-title":"J. Gen. Virol."},{"issue":"Pt. 11","key":"10.1016\/j.cyto.2016.05.009_b0105","doi-asserted-by":"crossref","first-page":"2495","DOI":"10.1099\/vir.0.052878-0","article-title":"Human cytomegalovirus directly modulates expression of chemokine CCL2 (MCP-1) during viral replication","volume":"94","author":"Hamilton","year":"2013","journal-title":"J. Gen. Virol."},{"issue":"1","key":"10.1016\/j.cyto.2016.05.009_b0110","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/2042-4280-1-7","article-title":"RCMV increases intimal hyperplasia by inducing inflammation, MCP-1 expression and recruitment of adventitial cells to intima","volume":"1","author":"Grudzinska","year":"2010","journal-title":"Herpesviridae"},{"key":"10.1016\/j.cyto.2016.05.009_b0115","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/S0022-510X(98)00061-6","article-title":"Time course of chemokines in the cerebrospinal fluid and serum during herpes simplex type 1 encephalitis","volume":"157","author":"Rosler","year":"1998","journal-title":"J. Neurol. Sci."},{"issue":"2","key":"10.1016\/j.cyto.2016.05.009_b0120","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1111\/j.1365-2249.2012.04644.x","article-title":"Normal ageing is associated with an increase in Th2 cells, MCP-1 (CCL1) and RANTES (CCL5), with differences in sCD40L and PDGF-AA within sexes","volume":"170","author":"Mansfield","year":"2012","journal-title":"Clin. Exp. Immunol."}],"container-title":["Cytokine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S104346661630093X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S104346661630093X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,11]],"date-time":"2018-09-11T12:56:01Z","timestamp":1536670561000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S104346661630093X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":24,"alternative-id":["S104346661630093X"],"URL":"https:\/\/doi.org\/10.1016\/j.cyto.2016.05.009","relation":{},"ISSN":["1043-4666"],"issn-type":[{"value":"1043-4666","type":"print"}],"subject":[],"published":{"date-parts":[[2016,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aqueous humor immune factors and cytomegalovirus (CMV) levels in CMV retinitis through treatment \u2013 The CRIGSS study","name":"articletitle","label":"Article Title"},{"value":"Cytokine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cyto.2016.05.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}