{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:56:28Z","timestamp":1791294988523,"version":"4.1.0"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100010609","name":"Gda\u0144ski Uniwersytet Medyczny","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010609","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cytokine"],"published-print":{"date-parts":[[2019,2]]},"DOI":"10.1016\/j.cyto.2018.11.005","type":"journal-article","created":{"date-parts":[[2018,11,9]],"date-time":"2018-11-09T21:41:39Z","timestamp":1541799699000},"page":"81-85","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["CCR5-\u039432 polymorphism is a genetic risk factor associated with dyslipidemia in patients with type 1 diabetes"],"prefix":"10.1016","volume":"114","author":[{"given":"Bartosz","family":"S\u0142omi\u0144ski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urszula","family":"\u0141awrynowicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Ryba-Stanis\u0142awowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Skrzypkowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jolanta","family":"My\u015bliwska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ma\u0142gorzata","family":"My\u015bliwiec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cyto.2018.11.005_b0005","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1007\/s00125-007-0921-8","article-title":"High prevalence of cardiovascular risk factors in children and adolescents with type 1 diabetes: a population-based study","volume":"51","author":"Margeirsdottir","year":"2008","journal-title":"Diabetologia"},{"key":"10.1016\/j.cyto.2018.11.005_b0010","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1007\/s00125-003-1116-6","article-title":"Mortality from heart disease in a cohort of 23,000 patients with insulin-treated diabetes","volume":"46","author":"Laing","year":"2003","journal-title":"Diabetologia"},{"key":"10.1016\/j.cyto.2018.11.005_b0015","first-page":"75","article-title":"Early diabetes-related complications in adolescents: risk factors and screening","volume":"63","author":"Daneman","year":"2005","journal-title":"Horm. Res."},{"key":"10.1016\/j.cyto.2018.11.005_b0020","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1001\/jama.281.8.727","article-title":"Prevalence and extent of atherosclerosis in adolescents and young adults: implications for prevention from the Pathobiological Determinants of Atherosclerosis in YouthStudy","volume":"281","author":"Strong","year":"1991","journal-title":"JAMA"},{"key":"10.1016\/j.cyto.2018.11.005_b0025","first-page":"254","article-title":"Potential influence of lipids in diabetic nephropathy: insights from experimental data and clinical studies","volume":"26","author":"Bonnet","year":"2000","journal-title":"DiabetesMetab."},{"key":"10.1016\/j.cyto.2018.11.005_b0030","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1038\/nri1882","article-title":"The immune response in atherosclerosis: a double-edged sword","volume":"6","author":"Hansson","year":"2006","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.cyto.2018.11.005_b0035","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1161\/ATVBAHA.107.161240","article-title":"Chemokines and cardiovascular risk","volume":"28","author":"Aukrust","year":"2008","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.cyto.2018.11.005_b0040","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1161\/ATVBAHA.108.165423","article-title":"A novel RANTES antagonist prevents progression of established atherosclerotic lesions in mice","volume":"28","author":"Braunersreuther","year":"2008","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.cyto.2018.11.005_b0045","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1161\/CIRCULATIONAHA.107.745091","article-title":"Combined inhibition of CCL2, CX3CR1, and CCR5 abrogates Ly6C(hi) and Ly6C(lo) monocytosis and almost abolishes atherosclerosis in hypercholesterolemic mice","volume":"117","author":"Combadi\u00e8re","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.cyto.2018.11.005_b0050","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1038\/ng0597-100","article-title":"Global distribution of the CCR5 gene 32-basepair deletion","volume":"16","author":"Martinson","year":"1997","journal-title":"Nat. Genet."},{"key":"10.1016\/j.cyto.2018.11.005_b0055","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1161\/CIRCGENETICS.109.897793","article-title":"Genetic association of the CCR5 region with lipid levels in at-risk cardiovascular patients","volume":"3","author":"Hyde","year":"2010","journal-title":"Circ. Cardiovasc. Genet."},{"key":"10.1016\/j.cyto.2018.11.005_b0060","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1038\/sj.gene.6363760","article-title":"Genetic variation at the chemokine receptors CCR5\/CCR2 in myocardial infarction","volume":"2","author":"Gonz\u00e1lez","year":"2001","journal-title":"Genes Immun."},{"key":"10.1016\/j.cyto.2018.11.005_b0065","doi-asserted-by":"crossref","first-page":"1972","DOI":"10.1161\/STROKEAHA.107.504381","article-title":"Common CCR5-del32 frameshift mutation associated with serum levels of inflammatory markers and cardiovascular disease risk in the Bruneck population","volume":"39","author":"Afzal","year":"2008","journal-title":"Stroke"},{"key":"10.1016\/j.cyto.2018.11.005_b0070","doi-asserted-by":"crossref","first-page":"637","DOI":"10.3324\/haematol.12239","article-title":"Role of polymorphisms of CC-chemokine receptor-5 gene in acute myocardial infarction and biological implications for longevity","volume":"93","author":"Balistreri","year":"2008","journal-title":"Haematologica"},{"key":"10.1016\/j.cyto.2018.11.005_b0075","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1111\/j.1365-2796.2005.01491.x","article-title":"CC chemokine receptor (CCR5) deletion polymorphism does not protect Czech males against early myocardial infarction","volume":"257","author":"Petrkova","year":"2005","journal-title":"J. Intern. Med."},{"key":"10.1016\/j.cyto.2018.11.005_b0080","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.thromres.2005.12.016","article-title":"Effects of polymorphisms in chemokine ligands and receptors on susceptibility to coronary artery disease","volume":"119","author":"Apostolakis","year":"2007","journal-title":"Thromb. Res."},{"key":"10.1016\/j.cyto.2018.11.005_b0085","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.cyto.2007.10.007","article-title":"Genetic control of chemokines in severe human internal carotid artery stenosis","volume":"41","author":"Ghilardi","year":"2008","journal-title":"Cytokine"},{"key":"10.1016\/j.cyto.2018.11.005_b0090","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.atherosclerosis.2005.06.041","article-title":"Polymorphisms in the CC-chemokine receptor-2 (CCR2) and -5 (CCR5) genes and risk of coronary heart disease among US women","volume":"186","author":"Pai","year":"2006","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.cyto.2018.11.005_b0095","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1310\/hct1201-24","article-title":"Maraviroc can improve lipid profiles in dyslipidemic patients with HIV: results from the MERIT trial","volume":"12","author":"MacInnes","year":"2011","journal-title":"HIV Clin. Trials."},{"key":"10.1016\/j.cyto.2018.11.005_b0100","doi-asserted-by":"crossref","first-page":"S62","DOI":"10.2337\/dc10-S062","article-title":"Diagnosis and classification of diabetes mellitus","volume":"33","author":"American Diabetes Association","year":"2010","journal-title":"Diabetes Care"},{"key":"10.1016\/j.cyto.2018.11.005_b0105","doi-asserted-by":"crossref","first-page":"2194","DOI":"10.2337\/diacare.26.7.2194","article-title":"Management of dyslipidemia in children and adolescents with diabetes","volume":"26","author":"American Diabetes Association","year":"2003","journal-title":"Diabetes Care"},{"key":"10.1016\/j.cyto.2018.11.005_b0110","doi-asserted-by":"crossref","first-page":"S6","DOI":"10.1016\/j.jpeds.2009.04.051","article-title":"Growth curves for cardio-metabolic risk factors in children and adolescents","volume":"155","author":"Cook","year":"2009","journal-title":"J. Pediatr."},{"key":"10.1016\/j.cyto.2018.11.005_b0115","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.2215\/CJN.01640309","article-title":"Measurement and estimation of GFR in children and adolescents","volume":"4","author":"Schwartz","year":"2009","journal-title":"CJASN"},{"key":"10.1016\/j.cyto.2018.11.005_b0120","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/clinchem\/18.6.499","article-title":"Estimation of the concentration of low density lipoprotein cholesterol in plasma, without the use of preparative ultra","volume":"18","author":"Friedewald","year":"1972","journal-title":"Clin. Chem."},{"key":"10.1016\/j.cyto.2018.11.005_b0125","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.mce.2016.09.009","article-title":"CCR5-\u039432 gene polymorphism is associated with retinopathy in patients with type 1 diabetes","volume":"439","author":"S\u0142omi\u0144ski","year":"2017","journal-title":"Mol. Cell Endocrinol."},{"issue":"2","key":"10.1016\/j.cyto.2018.11.005_b0130","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1038\/ng1706","article-title":"Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies","volume":"38","author":"Skol","year":"2006","journal-title":"Nat. Genet."},{"key":"10.1016\/j.cyto.2018.11.005_b0135","doi-asserted-by":"crossref","first-page":"123","DOI":"10.3109\/08820139.2013.847457","article-title":"The chemokine receptor 5 delta32 polymorphism and type 1 diabetes, Behcet's disease, and asthma: a meta-analysis","volume":"43","author":"Song","year":"2014","journal-title":"Immunol. Invest."},{"key":"10.1016\/j.cyto.2018.11.005_b0140","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1186\/s12881-014-0103-8","article-title":"Meta-analysis of diabetic nephropathy associated genetic variants in inflammation and angiogenesis involved in different biochemical pathways","volume":"15","author":"Nazir","year":"2014","journal-title":"BMC Med. Genet."},{"key":"10.1016\/j.cyto.2018.11.005_b0145","article-title":"CCR5-\u039432 gene polymorphism is related to celiac disease and autoimmune thyroiditis coincidence in patients with type 1 diabetes","author":"S\u0142omi\u0144ski","year":"2018","journal-title":"J. Diabetes Complicat."},{"key":"10.1016\/j.cyto.2018.11.005_b0150","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1111\/j.1399-5448.2010.00665.x","article-title":"Characterization of 33 488 children and adolescents with type 1 diabetes based on the gender-specific increase of cardiovascular risk factors","volume":"11","author":"Schwab","year":"2010","journal-title":"Pediatr. Diabetes"},{"key":"10.1016\/j.cyto.2018.11.005_b0155","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1056\/NEJM199304223281603","article-title":"Genetic and environmental influences on serum lipid levels in twins","volume":"328","author":"Heller","year":"1993","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.cyto.2018.11.005_b0160","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1007\/s12265-012-9363-x","article-title":"Cardiovascular disease risk in young people with type 1 diabetes","volume":"5","author":"Snell-Bergeon","year":"2012","journal-title":"J. Cardiovasc. Transl. Res."},{"key":"10.1016\/j.cyto.2018.11.005_b0165","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1194\/jlr.R300019-JLR200","article-title":"Effects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host","volume":"45","author":"Khovidhunkit","year":"2004","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.cyto.2018.11.005_b0170","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1111\/j.1476-5381.2010.01147.x","article-title":"Chemokine receptor CCR5: from AIDS to atherosclerosis","volume":"162","author":"Jones","year":"2011","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.cyto.2018.11.005_b0175","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s12872-016-0201-y","article-title":"Relationship between regulatory T cells subsets and lipid profile in dyslipidemic patients: a longitudinal study during atorvastatin treatment","volume":"16","author":"Guasti","year":"2016","journal-title":"BMC Cardiovasc. Disord"},{"key":"10.1016\/j.cyto.2018.11.005_b0180","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1172\/JCI63891","article-title":"Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis","volume":"123","author":"Klingenberg","year":"2013","journal-title":"J. Clin. Invest."}],"container-title":["Cytokine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043466618304174?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043466618304174?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T20:51:20Z","timestamp":1760907080000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1043466618304174"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2]]},"references-count":36,"alternative-id":["S1043466618304174"],"URL":"https:\/\/doi.org\/10.1016\/j.cyto.2018.11.005","relation":{},"ISSN":["1043-4666"],"issn-type":[{"value":"1043-4666","type":"print"}],"subject":[],"published":{"date-parts":[[2019,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"CCR5-\u039432 polymorphism is a genetic risk factor associated with dyslipidemia in patients with type 1 diabetes","name":"articletitle","label":"Article Title"},{"value":"Cytokine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cyto.2018.11.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}