{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T08:06:16Z","timestamp":1790755576654,"version":"4.1.0"},"reference-count":127,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Rafsanjan University of Medical Sciences"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cytokine"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1016\/j.cyto.2019.154896","type":"journal-article","created":{"date-parts":[[2019,10,25]],"date-time":"2019-10-25T12:08:17Z","timestamp":1572005297000},"page":"154896","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":77,"special_numbering":"C","title":["Role(s) of cytokines in pulpitis: Latest evidence and therapeutic approaches"],"prefix":"10.1016","volume":"126","author":[{"given":"Mohammad M.Y.","family":"Khorasani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gholamhossein","family":"Hassanshahi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aniela","family":"Brodzikowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossein","family":"Khorramdelazad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.cyto.2019.154896_b0005","article-title":"Acute dental pain and salivary biomarkers for stress and inflammation in patients with pulpal or periapical inflammation","volume":"33","author":"Rethnam Haug","year":"2019","journal-title":"J. Oral Facial Pain Headache"},{"issue":"2","key":"10.1016\/j.cyto.2019.154896_b0010","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/0003-9969(91)90077-8","article-title":"Microbiological studies of carious dentine from human teeth with irreversible pulpitis","volume":"36","author":"Hahn","year":"1991","journal-title":"Arch. Oral Biol."},{"issue":"3","key":"10.1016\/j.cyto.2019.154896_b0015","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/S0099-2399(81)80122-7","article-title":"Inflammatory response of the dental pulp to bacterial irritation","volume":"7","author":"Bergenholtz","year":"1981","journal-title":"J. Endod."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0020","doi-asserted-by":"crossref","first-page":"25","DOI":"10.18869\/acadpub.johe.6.1.25","article-title":"The prevalence of caries in the first permanent molars among students of 7 and 12 years of age in Rafsanjan, Iran, in 2009\u20132010","volume":"6","author":"YaghootiKhorasani","year":"2017","journal-title":"J. Occup. Health Epidemiol."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0025","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1177\/1753425909348527","article-title":"Expression of NOD2 is increased in inflamed human dental pulps and lipoteichoic acid-stimulated odontoblast-like cells","volume":"17","author":"Keller","year":"2011","journal-title":"Innate Immunity"},{"issue":"3","key":"10.1016\/j.cyto.2019.154896_b0030","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1177\/0022034511405390","article-title":"Pattern-recognition receptors in pulp defense","volume":"23","author":"Staquet","year":"2011","journal-title":"Adv. Dental Res."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0035","doi-asserted-by":"crossref","DOI":"10.1111\/jicd.12290","article-title":"Association of S100 calcium-binding protein A12, receptor for advanced glycation endproducts, and nuclear factor-\u03baB expression with inflammation in pulp tissues from tooth caries","volume":"9","author":"Khorasani","year":"2018","journal-title":"J. Invest. Clin. Dent."},{"key":"10.1016\/j.cyto.2019.154896_b0040","series-title":"Cytokines and chemokines. In: Mosaic of Autoimmunity","first-page":"127","author":"Tsuchida","year":"2019"},{"issue":"4","key":"10.1016\/j.cyto.2019.154896_b0045","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1177\/154405910708600403","article-title":"Chemokines in oral inflammatory diseases: apical periodontitis and periodontal disease","volume":"86","author":"Silva","year":"2007","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.cyto.2019.154896_b0050","doi-asserted-by":"crossref","first-page":"214","DOI":"10.3389\/fimmu.2015.00214","article-title":"Chemokine function in periodontal disease and oral cavity cancer","volume":"6","author":"Sahingur","year":"2015","journal-title":"Front. Immunol."},{"key":"10.1016\/j.cyto.2019.154896_b0055","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.cyto.2018.11.011","article-title":"Inflammasome and cytokine expression profiling in experimental periodontitis in the integrin \u03b26 null mouse","volume":"114","author":"Bi","year":"2019","journal-title":"Cytokine"},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0060","first-page":"129","article-title":"Inflammatory cytokine serum levels in sockets following extraction of teeth with apical periodontitis","volume":"12","author":"Amin","year":"2019","journal-title":"J. Int. Dental Med. Res."},{"issue":"12","key":"10.1016\/j.cyto.2019.154896_b0065","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1016\/j.joen.2009.09.032","article-title":"Identify and define all diagnostic terms for pulpal health and disease states","volume":"35","author":"Levin","year":"2009","journal-title":"J. Endod."},{"issue":"3","key":"10.1016\/j.cyto.2019.154896_b0070","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.joen.2018.11.017","article-title":"Microbiome of deep dentinal caries from reversible pulpitis to irreversible pulpitis","volume":"45","author":"Zheng","year":"2019","journal-title":"J. Endod."},{"issue":"11","key":"10.1016\/j.cyto.2019.154896_b0075","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0167289","article-title":"Biological markers for pulpal inflammation: a systematic review","volume":"11","author":"Rechenberg","year":"2016","journal-title":"PloS One"},{"issue":"3","key":"10.1016\/j.cyto.2019.154896_b0080","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1097\/00004770-200003000-00012","article-title":"Pulpal pain diagnosis\u2014a review","volume":"26","author":"Bender","year":"2000","journal-title":"J. Endod."},{"issue":"6","key":"10.1016\/j.cyto.2019.154896_b0085","doi-asserted-by":"crossref","first-page":"633","DOI":"10.2341\/06-000","article-title":"Tooth regeneration in operative dentistry","volume":"31","author":"N\u00f6r","year":"2006","journal-title":"Oper. Dentistry"},{"issue":"10","key":"10.1016\/j.cyto.2019.154896_b0090","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1097\/01.don.0000164138.49923.e5","article-title":"The application of tissue engineering to regeneration of pulp and dentin in endodontics","volume":"31","author":"Nakashima","year":"2005","journal-title":"J. Endod."},{"key":"10.1016\/j.cyto.2019.154896_b0095","doi-asserted-by":"crossref","first-page":"367","DOI":"10.3389\/fphys.2015.00367","article-title":"The perivascular niche and self-renewal of stem cells","volume":"6","author":"Oh","year":"2015","journal-title":"Front. Physiol."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0100","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1590\/S0103-64402011000100001","article-title":"Dental pulp tissue engineering","volume":"22","author":"Demarco","year":"2011","journal-title":"Brazilian Dental J."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0105","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1002\/jemt.10010","article-title":"Lymphatic vessels in the oral cavity: different structures for the same function","volume":"56","author":"Marchetti","year":"2002","journal-title":"Microsc. Res. Tech."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0110","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1002\/jemt.10006","article-title":"Lymphatic networks in the periodontal tissue and dental pulp as revealed by histochemical study","volume":"56","author":"Matsumoto","year":"2002","journal-title":"Microsc. Res. Tech."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0115","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/j.1600-0722.2008.00592.x","article-title":"Characterization of the dental lymphatic system and identification of cells immunopositive to specific lymphatic markers","volume":"117","author":"Berggreen","year":"2009","journal-title":"Eur. J. Oral Sci."},{"key":"10.1016\/j.cyto.2019.154896_b0120","unstructured":"Virtej, A., 2016. Vascular endothelial growth factors and receptors-from normal dental pulp to apical pathology."},{"key":"10.1016\/j.cyto.2019.154896_b0125","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1111\/j.1834-7819.2007.tb00525.x","article-title":"An overview of the dental pulp: its functions and responses to injury","volume":"52","author":"Yu","year":"2007","journal-title":"Aust. Dent. J."},{"issue":"6","key":"10.1016\/j.cyto.2019.154896_b0130","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.joen.2007.01.001","article-title":"Innate immune responses of the dental pulp to caries","volume":"33","author":"Hahn","year":"2007","journal-title":"J. Endod."},{"key":"10.1016\/j.cyto.2019.154896_b0135","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/230251","article-title":"Dental pulp defence and repair mechanisms in dental caries","volume":"2015","author":"Farges","year":"2015","journal-title":"Mediators Inflamm."},{"issue":"6","key":"10.1016\/j.cyto.2019.154896_b0140","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1080\/00016350410010045","article-title":"Effect of electrical tooth stimulation on blood flow and immunocompetent cells in rat dental pulp after sympathectomy","volume":"62","author":"Csillag","year":"2004","journal-title":"Acta Odontologica Scandinavica"},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0145","doi-asserted-by":"crossref","first-page":"5304","DOI":"10.3402\/jom.v3i0.5304","article-title":"Review of osteoimmunology and the host response in endodontic and periodontal lesions","volume":"3","author":"Graves","year":"2011","journal-title":"J. Oral Microbiol."},{"issue":"3","key":"10.1016\/j.cyto.2019.154896_b0150","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1600-9657.1990.tb00400.x","article-title":"The role of immune cytokines in the pathogenesis of periapical lesions","volume":"6","author":"Stashenko","year":"1990","journal-title":"Dent. Traumatol."},{"key":"10.1016\/j.cyto.2019.154896_b0155","doi-asserted-by":"crossref","first-page":"12549","DOI":"10.1038\/srep12549","article-title":"Toll-like receptor 4 signaling in neurons of trigeminal ganglion contributes to nociception induced by acute pulpitis in rats","volume":"5","author":"Lin","year":"2015","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.cyto.2019.154896_b0160","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.imbio.2010.08.006","article-title":"Cytokine production by human odontoblast-like cells upon Toll-like receptor-2 engagement","volume":"216","author":"Farges","year":"2011","journal-title":"Immunobiology"},{"issue":"2","key":"10.1016\/j.cyto.2019.154896_b0165","first-page":"209","article-title":"Up-regulation of TLR2 and TLR4 in high mobility group Box1-stimulated macrophages in pulpitis patients","volume":"20","author":"Mahmoudi","year":"2017","journal-title":"Iran. J. Basic Med. Sci."},{"issue":"10","key":"10.1016\/j.cyto.2019.154896_b0170","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1111\/iej.12921","article-title":"Astrocyte elevated gene-1 participates in the production of pro-inflammatory cytokines in dental pulp cells via NF-\u03baB signalling pathway","volume":"51","author":"Wu","year":"2018","journal-title":"Int. Endod. J."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0175","doi-asserted-by":"crossref","first-page":"58","DOI":"10.4103\/0973-029X.203795","article-title":"Pulpal changes associated with advanced periodontal disease: a histopathological study","volume":"21","author":"Gautam","year":"2017","journal-title":"J. Oral Maxillofacial Pathol.: JOMFP"},{"key":"10.1016\/j.cyto.2019.154896_b0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.joen.2019.02.014","article-title":"Neutrophil extracellular traps exert potential cytotoxic and proinflammatory effects in the dental pulp","author":"Holder","year":"2019","journal-title":"J. Endod."},{"issue":"11","key":"10.1016\/j.cyto.2019.154896_b0185","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1016\/j.joen.2013.07.003","article-title":"Absent in melanoma 2 (AIM2) in rat dental pulp mediates the inflammatory response during pulpitis","volume":"39","author":"Wang","year":"2013","journal-title":"J. Endod."},{"issue":"7","key":"10.1016\/j.cyto.2019.154896_b0190","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.joen.2007.01.002","article-title":"Update on the adaptive immune responses of the dental pulp","volume":"33","author":"Hahn","year":"2007","journal-title":"J. Endod."},{"key":"10.1016\/j.cyto.2019.154896_b0195","first-page":"14","article-title":"Associations between HBD3 and Pro-inflammatory cytokines in asymptomatic irreversible pulpitis","volume":"2","author":"Aminoshariae","year":"2017","journal-title":"Dent. Res. Mang."},{"issue":"2","key":"10.1016\/j.cyto.2019.154896_b0200","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/S0099-2399(06)81571-2","article-title":"Pathogenic mechanisms in pulpal disease","volume":"16","author":"Bergenholtz","year":"1990","journal-title":"J. Endod."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0205","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1080\/21655979.2019.1621135","article-title":"5-aza-2\u2019-deoxycytidine enhances lipopolysaccharide-induced inflammatory cytokine expression in human dental pulp cells by regulating TRAF6 methylation","volume":"10","author":"Feng","year":"2019","journal-title":"Bioengineered"},{"issue":"2","key":"10.1016\/j.cyto.2019.154896_b0210","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1097\/AIA.0b013e318034194e","article-title":"Cytokines, inflammation and pain","volume":"45","author":"Zhang","year":"2007","journal-title":"Int. Anesthesiol. Clin."},{"issue":"5","key":"10.1016\/j.cyto.2019.154896_b0215","doi-asserted-by":"crossref","first-page":"755","DOI":"10.2217\/bmm.10.81","article-title":"Cytokine patterns after therapy with Avonex\u00ae, Rebif\u00ae, Betaferon\u00ae and CinnoVex\u2122 in relapsing\u2013remitting multiple sclerosis in Iranian patients","volume":"4","author":"Arababadi","year":"2010","journal-title":"Biomarkers Med."},{"issue":"6","key":"10.1016\/j.cyto.2019.154896_b0220","doi-asserted-by":"crossref","DOI":"10.1111\/and.12685","article-title":"Inflammatory and anti-inflammatory cytokines in the seminal plasma of infertile men suffering from varicocele","volume":"49","author":"Zeinali","year":"2017","journal-title":"Andrologia"},{"issue":"11","key":"10.1016\/j.cyto.2019.154896_b0225","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1111\/j.1365-2591.2009.01605.x","article-title":"Sensory pulpal nerve fibres and trigeminal ganglion neurons express IL-1RI: a potential mechanism for development of inflammatory hyperalgesia","volume":"42","author":"Bletsa","year":"2009","journal-title":"Int. Endod. J."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0230","first-page":"66","article-title":"Melatonin attenuates inflammation of acute pulpitis subjected to dental pulp injury","volume":"7","author":"Li","year":"2015","journal-title":"Am. J. Transl. Res."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0235","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.joen.2016.09.003","article-title":"Pulpal tissue inflammatory reactions after experimental pulpal exposure in mice","volume":"43","author":"He","year":"2017","journal-title":"J. Endod."},{"issue":"2","key":"10.1016\/j.cyto.2019.154896_b0240","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1177\/0022034515612086","article-title":"Immune cells and molecular networks in experimentally induced pulpitis","volume":"95","author":"Renard","year":"2016","journal-title":"J. Dent. Res."},{"issue":"2","key":"10.1016\/j.cyto.2019.154896_b0245","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1177\/0022034515612022","article-title":"Conditional TNF-\u03b1 overexpression in the tooth and alveolar bone results in painful pulpitis and osteitis","volume":"95","author":"Hall","year":"2016","journal-title":"J. Dent. Res."},{"issue":"4","key":"10.1016\/j.cyto.2019.154896_b0250","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1111\/j.1365-2591.2011.01983.x","article-title":"Cytokine expression in response to root canal infection in gnotobiotic mice","volume":"45","author":"Maciel","year":"2012","journal-title":"Int. Endod. J."},{"issue":"10","key":"10.1016\/j.cyto.2019.154896_b0255","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1111\/iej.12240","article-title":"Immunohistochemical localization of NALP 3 inflammasome in experimental periapical lesions","volume":"47","author":"Liu","year":"2014","journal-title":"Int. Endod. J."},{"issue":"5","key":"10.1016\/j.cyto.2019.154896_b0260","doi-asserted-by":"crossref","first-page":"e70","DOI":"10.1016\/j.tripleo.2008.01.025","article-title":"The effects of mineral trioxide aggregates on cytokine production by mouse pulp tissue","volume":"105","author":"Silva","year":"2008","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endodontol."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0265","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.cyto.2007.08.003","article-title":"Effects of TGF-\u03b21 on interleukin profile of human dental pulp and odontoblasts","volume":"40","author":"P\u00e4\u00e4kk\u00f6nen","year":"2007","journal-title":"Cytokine"},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0270","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5395\/JKACD.2005.30.1.001","article-title":"Effects of Enterococcus faecalis sonicated extracts on IL-2, IL-4 and TGF-\u03b21 production from human lymphocytes","volume":"30","author":"Kim","year":"2005","journal-title":"J. Korean Acad. Conserv. Dentist."},{"issue":"4","key":"10.1016\/j.cyto.2019.154896_b0275","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.joen.2016.11.003","article-title":"The effects of M1 and M2 macrophages on odontogenic differentiation of human dental pulp cells","volume":"43","author":"Park","year":"2017","journal-title":"J. Endod."},{"key":"10.1016\/j.cyto.2019.154896_b0280","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.archoralbio.2019.05.003","article-title":"Interleukin-17 plays a role in pulp inflammation partly by WNT5A protein induction","volume":"103","author":"Liu","year":"2019","journal-title":"Arch. Oral Biol."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0285","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1111\/iej.12274","article-title":"Absence of interleukin 22 affects the oral microbiota and the progression of induced periapical lesions in murine teeth","volume":"48","author":"De Oliveira","year":"2015","journal-title":"Int. Endod. J."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0290","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1186\/s12903-018-0586-3","article-title":"Increased interleukin 1\u03b1 and interleukin 1\u03b2 expression is involved in the progression of periapical lesions in primary teeth","volume":"18","author":"Yang","year":"2018","journal-title":"BMC Oral Health"},{"issue":"3","key":"10.1016\/j.cyto.2019.154896_b0295","doi-asserted-by":"crossref","first-page":"232","DOI":"10.5395\/JKACD.2002.27.3.232","article-title":"Interleukin-6 and interleukin-10 in experimentally induced rat pulpal inflammation","volume":"27","author":"Chang","year":"2002","journal-title":"J. Korean Acad. Conserv. Dentistr."},{"issue":"2","key":"10.1016\/j.cyto.2019.154896_b0300","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/S1079-2104(99)70118-6","article-title":"Increased interleukin-8 expression in inflamed human dental pulps","volume":"88","author":"Huang","year":"1999","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endodontol."},{"issue":"3\u20134","key":"10.1016\/j.cyto.2019.154896_b0305","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/S1043-4666(03)00116-9","article-title":"Cytokine gene expression\u2014part of host defence in pulpitis","volume":"22","author":"Zehnder","year":"2003","journal-title":"Cytokine"},{"issue":"3","key":"10.1016\/j.cyto.2019.154896_b0310","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1097\/00004770-200203000-00003","article-title":"Interleukin-1\u03b2 activity and collagen synthesis in human dental pulp fibroblasts","volume":"28","author":"Barkhordar","year":"2002","journal-title":"J. Endod."},{"issue":"6","key":"10.1016\/j.cyto.2019.154896_b0315","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/S0099-2399(98)80022-8","article-title":"Effects of interleukin-1\u03b2 on human pulpal fibroblast proliferation and collagen synthesis","volume":"24","author":"Lertchirakarn","year":"1998","journal-title":"J. Endod."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0320","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0113334","article-title":"Decreasing NF-\u03baB expression enhances odontoblastic differentiation and collagen expression in dental pulp stem cells exposed to inflammatory cytokines","volume":"10","author":"Hozhabri","year":"2015","journal-title":"PloS One"},{"issue":"4","key":"10.1016\/j.cyto.2019.154896_b0325","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1067\/moe.2002.122641","article-title":"A mouse model of inflammatory root resorption induced by pulpal infection","volume":"93","author":"Balto","year":"2002","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endodontol."},{"key":"10.1016\/j.cyto.2019.154896_b0330","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.archoralbio.2015.10.008","article-title":"IL-1\u03b2-induced MCP-1 expression and secretion of human dental pulp cells is related to TAK1, MEK\/ERK, and PI3K\/Akt signaling pathways","volume":"61","author":"Chang","year":"2016","journal-title":"Arch. Oral Biol."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0335","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/odi.12219","article-title":"IL-1\u03b2-induced matrix metalloproteinase-3 regulates cell proliferation in rat dental pulp cells","volume":"21","author":"Ozeki","year":"2015","journal-title":"Oral Dis."},{"issue":"12","key":"10.1016\/j.cyto.2019.154896_b0340","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1111\/iej.12411","article-title":"Effects of JNK 1\/2 on the inflammation cytokine TNF-\u03b1-enhanced production of MMP-3 in human dental pulp fibroblast-like cells","volume":"48","author":"Goda","year":"2015","journal-title":"Int. Endod. J."},{"issue":"5","key":"10.1016\/j.cyto.2019.154896_b0345","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1111\/odi.12165","article-title":"Cytokines induce MMP-3-regulated proliferation of embryonic stem cell-derived odontoblast-like cells","volume":"20","author":"Ozeki","year":"2014","journal-title":"Oral Dis."},{"issue":"4","key":"10.1016\/j.cyto.2019.154896_b0350","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0124542","article-title":"Interleukin-1\u03b2-induced autophagy-related gene 5 regulates proliferation of embryonic stem cell-derived odontoblastic cells","volume":"10","author":"Ozeki","year":"2015","journal-title":"PloS One"},{"issue":"6","key":"10.1016\/j.cyto.2019.154896_b0355","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.joen.2012.02.030","article-title":"Regulation of vascular cell adhesion molecule-1 in dental pulp cells by interleukin-1\u03b2: the role of prostanoids","volume":"38","author":"Chang","year":"2012","journal-title":"J. Endod."},{"issue":"6","key":"10.1016\/j.cyto.2019.154896_b0360","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1111\/iej.12030","article-title":"Cytokines as diagnostic markers of pulpal inflammation","volume":"46","author":"Elsalhy","year":"2013","journal-title":"Int. Endod. J."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0365","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/1471-2172-12-9","article-title":"Caries induced cytokine network in the odontoblast layer of human teeth","volume":"12","author":"Horst","year":"2011","journal-title":"BMC Immunol."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0370","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.joen.2009.09.022","article-title":"Effect of proinflammatory cytokines on the expression and regulation of human beta-defensin 2 in human dental pulp cells","volume":"36","author":"Kim","year":"2010","journal-title":"J. Endod."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0375","first-page":"129","article-title":"Effect of neuropeptides on human dental pulp cells; mRNA expression of proinflammatory cytokines","volume":"45","author":"Shida","year":"2011","journal-title":"J. Osaka Dental Univ."},{"issue":"3","key":"10.1016\/j.cyto.2019.154896_b0380","first-page":"113","article-title":"Relation between pulpal neuropeptides and dental caries","volume":"5","author":"Haghighi","year":"2010","journal-title":"Iran. Endod. J."},{"issue":"6","key":"10.1016\/j.cyto.2019.154896_b0385","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1111\/iej.12339","article-title":"IL-17 stimulates the production of the inflammatory chemokines IL-6 and IL-8 in human dental pulp fibroblasts","volume":"48","author":"Xiong","year":"2015","journal-title":"Int. Endod. J."},{"issue":"6","key":"10.1016\/j.cyto.2019.154896_b0390","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/S0099-2399(97)80184-7","article-title":"Detection of human IL-2 in normal and inflamed dental pulps","volume":"23","author":"Rauschenberger","year":"1997","journal-title":"J. Endod."},{"issue":"9","key":"10.1016\/j.cyto.2019.154896_b0395","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1097\/00004770-200209000-00006","article-title":"Evaluating IL-2 levels in human pulp tissue","volume":"28","author":"Anderson","year":"2002","journal-title":"J. Endod."},{"issue":"3","key":"10.1016\/j.cyto.2019.154896_b0400","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1097\/00004770-200203000-00014","article-title":"T lymphocyte subpopulations and interleukin-2, interferon-\u03b3, and interleukin-4 in rat pulpitis experimentally induced by specific bacteria","volume":"28","author":"Kim","year":"2002","journal-title":"J. Endod."},{"issue":"3","key":"10.1016\/j.cyto.2019.154896_b0405","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/S1079-2104(03)00067-2","article-title":"Immunolocalization of interleukin 4, interleukin 6, and lymphotoxin \u03b1 in dental granulomas","volume":"96","author":"de S\u00e1","year":"2003","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endodontol."},{"issue":"3","key":"10.1016\/j.cyto.2019.154896_b0410","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1097\/00004770-200203000-00008","article-title":"Interleukin-10 inhibits expression of interleukin-6 and-8 mRNA in human dental pulp cell cultures via nuclear factor-\u03baB deactivation","volume":"28","author":"Tokuda","year":"2002","journal-title":"J. Endod."},{"issue":"2","key":"10.1016\/j.cyto.2019.154896_b0415","doi-asserted-by":"crossref","first-page":"198","DOI":"10.4103\/0976-237X.183059","article-title":"Evaluation of salivary interleukin-6 in children with early childhood caries after treatment","volume":"7","author":"Menon","year":"2016","journal-title":"Contemporary Clin. Dentistr."},{"issue":"2","key":"10.1016\/j.cyto.2019.154896_b0420","doi-asserted-by":"crossref","first-page":"323","DOI":"10.37358\/RC.17.2.5445","article-title":"Detection and assessment of interleukin 6 in irreversible pulp inflamation","volume":"68","author":"Giuroiu","year":"2017","journal-title":"Rev. Chim."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0425","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s00784-014-1227-0","article-title":"Effect of interleukin-1\u03b2 on ICAM-1 expression of dental pulp cells: role of PI3K\/Akt, MEK\/ERK, and cyclooxygenase","volume":"19","author":"Chang","year":"2015","journal-title":"Clin. Oral Invest."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0430","article-title":"Analysis of Interleukin 17A in periapical abscess and granuloma lesions","volume":"30","author":"Ferreira","year":"2016","journal-title":"Brazil. Oral Res."},{"issue":"5","key":"10.1016\/j.cyto.2019.154896_b0435","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1016\/j.joen.2018.02.004","article-title":"Inhibition of SOX9 promotes inflammatory and immune responses of dental pulp","volume":"44","author":"Luo","year":"2018","journal-title":"J. Endod."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0440","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.joen.2012.09.006","article-title":"Camphorquinone inhibits odontogenic differentiation of dental pulp cells and triggers release of inflammatory cytokines","volume":"39","author":"Kim","year":"2013","journal-title":"J. Endod."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0445","first-page":"18","article-title":"In vitro effect of hydroalcoholic extract of aloe vera and 0.2% chlorhexidine mouthwash on Streptococcus sanguinis, Streptococcus salivarius and Streptococcus mutans","volume":"36","author":"Shakerian","year":"2018","journal-title":"Shahid Beheshti Univ. Dental J."},{"key":"10.1016\/j.cyto.2019.154896_b0450","unstructured":"Li, C., et al., 2012. Preoperative oral nonsteroidal anti-inflammatory drugs for the success of the inferior alveolar nerve block in irreversible pulpitis treatment: a systematic review and meta-analysis based on randomized controlled trials."},{"issue":"1","key":"10.1016\/j.cyto.2019.154896_b0455","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/aej.12125","article-title":"Efficacy and safety of articaine versus lidocaine for irreversible pulpitis treatment: a systematic review and meta-analysis of randomised controlled trials","volume":"42","author":"Su","year":"2016","journal-title":"Aust. Endod. J."},{"issue":"14","key":"10.1016\/j.cyto.2019.154896_b0460","first-page":"31","article-title":"Phytochemical profiles of propolis Trigona spp. from three regions in Indonesia using GC-MS","volume":"6","author":"Kalsum","year":"2016","journal-title":"J. Biol. Agric. Healthcare"},{"issue":"5","key":"10.1016\/j.cyto.2019.154896_b0465","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1016\/j.sjbs.2016.12.019","article-title":"Interleukin-6 expression on inflamed rat dental pulp tissue after capped with Trigona sp. propolis from south, Sulawesi, Indonesia","volume":"24","author":"Sabir","year":"2017","journal-title":"Saudi J. Biol. Sci."},{"issue":"4","key":"10.1016\/j.cyto.2019.154896_b0470","first-page":"259","article-title":"Quercetin decreases Th17 production by down-regulation of MAPK-TLR4 signaling pathway on T cells in dental pulpitis","volume":"19","author":"Hashemi","year":"2018","journal-title":"J. Dent."},{"issue":"8","key":"10.1016\/j.cyto.2019.154896_b0475","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1177\/154405910508400815","article-title":"Effect of NOS inhibitor on cytokine and COX2 expression in rat pulpitis","volume":"84","author":"Kawashima","year":"2005","journal-title":"J. Dent. Res."},{"issue":"4","key":"10.1016\/j.cyto.2019.154896_b0480","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.joen.2008.01.015","article-title":"Terrein reduces pulpal inflammation in human dental pulp cells","volume":"34","author":"Lee","year":"2008","journal-title":"J. Endod."},{"issue":"9","key":"10.1016\/j.cyto.2019.154896_b0485","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1016\/j.joen.2014.04.001","article-title":"Down-regulation of inflammatory mediator synthesis and infiltration of inflammatory cells by MMP-3 in experimentally induced rat pulpitis","volume":"40","author":"Takimoto","year":"2014","journal-title":"J. Endod."},{"issue":"12","key":"10.1016\/j.cyto.2019.154896_b0490","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0052523","article-title":"The anti-inflammatory effects of matrix metalloproteinase-3 on irreversible pulpitis of mature erupted teeth","volume":"7","author":"Eba","year":"2012","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.cyto.2019.154896_b0495","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1111\/bph.12404","article-title":"Fluocinolone acetonide partially restores the mineralization of LPS-stimulated dental pulp cells through inhibition of NF-\u03baB pathway and activation of AP-1 pathway","volume":"170","author":"Liu","year":"2013","journal-title":"Br. J. Pharmacol."},{"issue":"4","key":"10.1016\/j.cyto.2019.154896_b0500","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1097\/00004770-200304000-00010","article-title":"Effect of an intraosseous injection of depo-medrol on pulpal concentrations of PGE2 and IL-8 in untreated irreversible pulpitis","volume":"29","author":"Isett","year":"2003","journal-title":"J. Endod."},{"key":"10.1016\/j.cyto.2019.154896_b0505","doi-asserted-by":"crossref","unstructured":"Dias, T.R., et al., 2018. Nutritional factors and male reproduction.","DOI":"10.1016\/B978-0-12-801238-3.64616-0"},{"issue":"3","key":"10.1016\/j.cyto.2019.154896_b0510","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/iej.12312","article-title":"Catechins inhibit vascular endothelial growth factor production and cyclooxygenase-2 expression in human dental pulp cells","volume":"48","author":"Nakanishi","year":"2015","journal-title":"Int. Endod. J."},{"issue":"17\u201318","key":"10.1016\/j.cyto.2019.154896_b0515","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.lfs.2010.02.017","article-title":"Tea catechins reduce inflammatory reactions via mitogen-activated protein kinase pathways in toll-like receptor 2 ligand-stimulated dental pulp cells","volume":"86","author":"Hirao","year":"2010","journal-title":"Life Sci."},{"issue":"3","key":"10.1016\/j.cyto.2019.154896_b0520","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1038\/ijos.2013.63","article-title":"Inhibition of matrix metalloproteinases expression in human dental pulp cells by all-trans retinoic acid","volume":"6","author":"Kim","year":"2014","journal-title":"Int. J. Oral Sci."},{"issue":"2","key":"10.1016\/j.cyto.2019.154896_b0525","doi-asserted-by":"crossref","first-page":"225","DOI":"10.2334\/josnusd.53.225","article-title":"Use of aminoguanidine, a selective inducible nitric oxide synthase inhibitor, to evaluate the role of nitric oxide in periapical inflammation","volume":"53","author":"Farhad","year":"2011","journal-title":"J. Oral Sci."},{"issue":"4","key":"10.1016\/j.cyto.2019.154896_b0530","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1111\/j.0143-2885.2007.01223.x","article-title":"The effect of chemical inhibition of matrix metalloproteinases on the size of experimentally induced apical periodontitis","volume":"40","author":"Tj\u00e4derhane","year":"2007","journal-title":"Int. Endod. J."},{"issue":"2","key":"10.1016\/j.cyto.2019.154896_b0535","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.joen.2016.10.020","article-title":"ASH1L suppresses matrix metalloproteinase through mitogen-activated protein kinase signaling pathway in pulpitis","volume":"43","author":"Bei","year":"2017","journal-title":"J. Endod."},{"issue":"3","key":"10.1016\/j.cyto.2019.154896_b0540","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/iej.12303","article-title":"Anti-inflammatory effects of glutamine on LPS-stimulated human dental pulp cells correlate with activation of MKP-1 and attenuation of the MAPK and NF-\u03baB pathways","volume":"48","author":"Kim","year":"2015","journal-title":"Int. Endod. J."},{"key":"10.1016\/j.cyto.2019.154896_b0545","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/385127","article-title":"The anti-inflammatory effect of human telomerase-derived peptide on P. gingivalis lipopolysaccharide-induced inflammatory cytokine production and its mechanism in human dental pulp cells","author":"Ko","year":"2015","journal-title":"Mediators Inflamm."},{"issue":"1\u20133","key":"10.1016\/j.cyto.2019.154896_b0550","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.ejphar.2010.06.059","article-title":"Effects of sappanchalcone on the cytoprotection and anti-inflammation via heme oxygenase-1 in human pulp and periodontal ligament cells","volume":"644","author":"Jeong","year":"2010","journal-title":"Eur. J. Pharmacol."},{"issue":"6","key":"10.1016\/j.cyto.2019.154896_b0555","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/j.joen.2013.02.003","article-title":"Ketoprofen inhibits expression of inflammatory mediators in human dental pulp cells","volume":"39","author":"Choi","year":"2013","journal-title":"J. Endod."},{"issue":"33","key":"10.1016\/j.cyto.2019.154896_b0560","first-page":"2451","article-title":"Inhibition of lipopolysaccharide-induced expression of cyclooxygenase-2 by Zingiber cassumunar Roxb. constituents in human dental pulp cells","volume":"7","author":"Aupaphong","year":"2013","journal-title":"J. Medicinal Plants Res."},{"issue":"4","key":"10.1016\/j.cyto.2019.154896_b0565","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.joen.2008.12.012","article-title":"Anti-inflammatory effect of peroxisome proliferator activated receptor gamma on human dental pulp cells","volume":"35","author":"Yu","year":"2009","journal-title":"J. Endod."},{"key":"10.1016\/j.cyto.2019.154896_b0570","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.archoralbio.2018.11.022","article-title":"Betamethasone suppresses the inflammatory response in LPS-stimulated dental pulp cells through inhibition of NF-\u03baB","volume":"98","author":"Wang","year":"2019","journal-title":"Arch. Oral Biol."},{"issue":"4","key":"10.1016\/j.cyto.2019.154896_b0575","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.joen.2009.01.004","article-title":"Cholinoceptor modulation on nitric oxide regulates prostaglandin E2 and metalloproteinase-3 production in experimentally induced inflammation of rat dental pulp","volume":"35","author":"Pita","year":"2009","journal-title":"J. Endod."},{"key":"10.1016\/j.cyto.2019.154896_b0580","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/9371403","article-title":"Effect of 4-allyl-1-hydroxy-2-methoxybenzene (eugenol) on inflammatory and apoptosis processes in dental pulp fibroblasts","volume":"2016","author":"Mart\u00ednez-Herrera","year":"2016","journal-title":"Mediators Inflamm."},{"key":"10.1016\/j.cyto.2019.154896_b0585","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.archoralbio.2018.10.020","article-title":"Resveratrol represses tumor necrosis factor \u03b1\/c-Jun N-terminal kinase signaling via autophagy in human dental pulp stem cells","volume":"97","author":"Wang","year":"2019","journal-title":"Arch. Oral Biol."},{"issue":"2","key":"10.1016\/j.cyto.2019.154896_b0590","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.jcma.2017.04.013","article-title":"Scutellaria baicalensis ameliorates the destruction of periodontal ligament via inhibition of inflammatory cytokine expression","volume":"81","author":"Kim","year":"2018","journal-title":"J. Chin. Med. Assoc."},{"issue":"9","key":"10.1016\/j.cyto.2019.154896_b0595","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1016\/j.joen.2011.05.031","article-title":"In vivo host interactions with mineral trioxide aggregate and calcium hydroxide: inflammatory molecular signaling assessment","volume":"37","author":"Reyes-Carmona","year":"2011","journal-title":"J. Endod."},{"issue":"9","key":"10.1016\/j.cyto.2019.154896_b0600","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1902\/jop.1996.67.9.900","article-title":"Efficacy of a sonic toothbrush on inflammation and probing depth in adult periodontitis","volume":"67","author":"O'Beirne","year":"1996","journal-title":"J. Periodontol."},{"issue":"2","key":"10.1016\/j.cyto.2019.154896_b0605","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1902\/jop.2009.070672","article-title":"Effect of anti-infective mechanical therapy on clinical parameters and cytokine levels in human peri-implant diseases","volume":"80","author":"Duarte","year":"2009","journal-title":"J. Periodontol."},{"issue":"2","key":"10.1016\/j.cyto.2019.154896_b0610","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1034\/j.1600-051x.2000.027002134.x","article-title":"Clinical benefits of oral irrigation for periodontitis are related to reduction of pro-inflammatory cytokine levels and plaque","volume":"27","author":"Cutler","year":"2000","journal-title":"J. Clin. Periodontol."},{"issue":"12","key":"10.1016\/j.cyto.2019.154896_b0615","doi-asserted-by":"crossref","first-page":"2024","DOI":"10.1016\/j.joen.2014.08.015","article-title":"Biocompatibility of new calcium aluminate cement: tissue reaction and expression of inflammatory mediators and cytokines","volume":"40","author":"Garcia","year":"2014","journal-title":"J. Endod."},{"key":"10.1016\/j.cyto.2019.154896_b0620","doi-asserted-by":"crossref","DOI":"10.1111\/idh.12395","article-title":"Effect of two post-surgical cleansing protocols on early periodontal wound healing and cytokine levels following osseous resective surgery: a randomized controlled study","author":"Sijari","year":"2019","journal-title":"Int. J. Dental Hyg."},{"issue":"3","key":"10.1016\/j.cyto.2019.154896_b0625","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/jre.12311","article-title":"Effects of new over-the-counter periodontal ointment-containing applicator with single-tuft brush on cytokine levels in gingival crevicular fluid during supportive periodontal therapy phase: a randomized double-blind clinical trial","volume":"51","author":"Takeuchi-Hatanaka","year":"2016","journal-title":"J. Periodontal Res."},{"key":"10.1016\/j.cyto.2019.154896_b0630","first-page":"1","article-title":"Cytokine levels in gingival crevicular fluid during orthodontic treatment with aligners compared to conventional labial fixed appliances: a 3-week clinical study","author":"Gujar","year":"2019","journal-title":"Acta Odontologica Scandinavica"},{"issue":"5","key":"10.1016\/j.cyto.2019.154896_b0635","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1007\/s00056-019-00184-8","article-title":"Comparison of crevicular fluid cytokine levels after the application of surface sealants","volume":"80","author":"\u015een","year":"2019","journal-title":"J. Orofacial Orthoped.\/Fortschritte der Kieferorthop\u00e4die"}],"container-title":["Cytokine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043466619303254?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043466619303254?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T20:55:35Z","timestamp":1760907335000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1043466619303254"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":127,"alternative-id":["S1043466619303254"],"URL":"https:\/\/doi.org\/10.1016\/j.cyto.2019.154896","relation":{},"ISSN":["1043-4666"],"issn-type":[{"value":"1043-4666","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role(s) of cytokines in pulpitis: Latest evidence and therapeutic approaches","name":"articletitle","label":"Article Title"},{"value":"Cytokine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cyto.2019.154896","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"154896"}}