{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T09:18:14Z","timestamp":1762161494388,"version":"build-2065373602"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,11,25]],"date-time":"2020-11-25T00:00:00Z","timestamp":1606262400000},"content-version":"vor","delay-in-days":269,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cytokine"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1016\/j.cyto.2019.154931","type":"journal-article","created":{"date-parts":[[2019,11,26]],"date-time":"2019-11-26T11:59:29Z","timestamp":1574769569000},"page":"154931","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Strongyloides venezuelensis-infection alters the profile of cytokines and liver inflammation in mice co-infected with Schistosoma mansoni"],"prefix":"10.1016","volume":"127","author":[{"given":"Michelle Carvalho","family":"de Rezende","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Marcelo Peixoto","family":"Moreira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura Liana Maggi","family":"Fernandes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3037-4161","authenticated-orcid":false,"given":"Vanessa Fernandes","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah","family":"Negr\u00e3o-Corr\u00eaa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cyto.2019.154931_b0005","unstructured":"World Health Organization, Schistosomiasis. In. World Health Organization, 2016 <https:\/\/www.who.int\/gho\/neglected_diseases\/schistosomiasis\/en\/>."},{"key":"10.1016\/j.cyto.2019.154931_b0010","unstructured":"World Health Organization, Soil Transmitted Helminthiases. Eliminating soil-transmitted helminthiases as a public health problem in children, Progress report 2001\u20132010 and strategic plan 2011\u20132020, 2012."},{"key":"10.1016\/j.cyto.2019.154931_b0015","first-page":"11","article-title":"Albendazole and ivermectin for the control of soil-transmitted helminths in an area with high prevalence of Strongyloides stercoralis and hookworm in northwestern Argentina: a community-based pragmatic study","volume":"9","author":"Echaz\u00fa","year":"2017","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"10","key":"10.1016\/j.cyto.2019.154931_b0020","doi-asserted-by":"crossref","first-page":"e0005685","DOI":"10.1371\/journal.pntd.0005685","article-title":"Strongyloides stercoralis is associated with significant morbidity in rural Cambodia, including stunting in children","volume":"11","author":"Forrer","year":"2017","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.cyto.2019.154931_b0025","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1017\/S0031182008000346","article-title":"The health impact of polyparasitism in humans: are we under-estimating the burden of parasitic diseases?","volume":"135","author":"Pullan","year":"2008","journal-title":"Parasitology"},{"issue":"1","key":"10.1016\/j.cyto.2019.154931_b0030","doi-asserted-by":"crossref","first-page":"e0005310","DOI":"10.1371\/journal.pntd.0005310","article-title":"Diagnosing polyparasitism in a high-prevalence setting in Beira, Mozambique: detection of intestinal parasites in fecal samples by microscopy and Real-Time PCR","volume":"11","author":"Meurs","year":"2017","journal-title":"PLoS Negl.Trop. Dis."},{"key":"10.1016\/j.cyto.2019.154931_b0035","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1073\/pnas.0707221105","article-title":"Ecological rules governing helminth-microparasite coinfection","volume":"105","author":"Graham","year":"2008","journal-title":"Proc. Natl. Acad. Sci. United States"},{"issue":"8","key":"10.1016\/j.cyto.2019.154931_b0040","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1186\/s13071-015-1167-9","article-title":"The importance of multiparasitism: examining the consequences of co-infections for human and animal health","volume":"20","author":"Vaumourin","year":"2015","journal-title":"Parasites Vectors"},{"issue":"12","key":"10.1016\/j.cyto.2019.154931_b0045","doi-asserted-by":"crossref","first-page":"4601","DOI":"10.1007\/s00436-015-4706-6","article-title":"Effect of different stages of Schistosoma mansoni infection on the parasite burden and immune response to Strongyloides venezuelensis in co-infected mice","volume":"114","author":"Rezende","year":"2015","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.cyto.2019.154931_b0050","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0020-7519(90)90173-K","article-title":"Strongyloides venezuelensis infections in mice","volume":"20","author":"Sato","year":"1990","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.cyto.2019.154931_b0055","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1128\/IAI.72.2.1135-1142.2004","article-title":"Platelet-activating factor receptor deficiency delays elimination of adult worms but reduces fecundity in Strongyloides venezuelensis-infected mice","volume":"72","author":"Negr\u00e3o-Corr\u00eaa","year":"2004","journal-title":"Infect. Immun."},{"key":"10.1016\/j.cyto.2019.154931_b0060","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1084\/jem.20042202","article-title":"IL-18 with IL-2 protects against Strongyloides venezuelensis infection by activating mucosal mast cell\u2013dependent type 2 innate immunity","volume":"202","author":"Sasaki","year":"2005","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.cyto.2019.154931_b0065","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1016\/j.ijpara.2006.05.005","article-title":"Expression of IL-4 receptor on non-bone marrow-derived cells is necessary for the timely elimination of Strongyloides venezuelensis in mice, but not for intestinal IL-4 production","volume":"36","author":"Negr\u00e3o-Corr\u00eaa","year":"2006","journal-title":"Int. J. Parasitol."},{"issue":"1 Suppl","key":"10.1016\/j.cyto.2019.154931_b0070","first-page":"e432","article-title":"Major histocompatibility complex (MHC) class II but not MHC class I molecules are required for efficient control of Strongyloides venezuelensis infection in mice","volume":"128","author":"Rodrigues","year":"2009","journal-title":"Immunology"},{"key":"10.1016\/j.cyto.2019.154931_b0075","doi-asserted-by":"crossref","unstructured":"E.S. Ara\u00fajo, C.A. de Jesus Pereira, A.T. de Moura Pereira, J.M. Moreira, M.C. de Rezende, J.L. Rodrigues, M.M. Teixeira, D. Negr\u00e3o-Corr\u00eaa, The role of IL-33\/ST2, IL-4, and eosinophils on the airway hyperresponsiveness induced byStrongyloidesvenezuelensis in BALB\/c mice. The role of IL-33\/ST2, IL-4, and eosinophils on the airway hyperresponsiveness induced by Strongyloides venezuelensis in BALB\/c mice. Parasitology Research 115(8) (2016) 3107\u20133117.","DOI":"10.1007\/s00436-016-5066-6"},{"key":"10.1016\/j.cyto.2019.154931_b0080","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1038\/nri843","article-title":"The immunobiology of schistosomiasis","volume":"2","author":"Pearce","year":"2002","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.cyto.2019.154931_b0085","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/j.1365-3024.2009.01098.x","article-title":"Immunopathogenesis of human schistosomiasis","volume":"31","author":"Burke","year":"2009","journal-title":"Parasite Immunol."},{"issue":"5","key":"10.1016\/j.cyto.2019.154931_b0090","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.pt.2005.03.003","article-title":"Comparison of skin invasion among three major species of Schistosoma","volume":"21","author":"He","year":"2005","journal-title":"Trends of Parasitology"},{"key":"10.1016\/j.cyto.2019.154931_b0095","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.idc.2012.03.004","article-title":"Schistosomiasis","volume":"26","author":"Gryseels","year":"2012","journal-title":"Infect. Dis. Clin. North Am."},{"issue":"4","key":"10.1016\/j.cyto.2019.154931_b0100","first-page":"89","article-title":"The Schistosoma granuloma: friend or foe?","volume":"15","author":"Hams","year":"2013","journal-title":"Front. Immunol."},{"issue":"2","key":"10.1016\/j.cyto.2019.154931_b0105","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1002\/path.2277","article-title":"Cellular and molecular mechanisms of fibrosis","volume":"214","author":"Wynn","year":"2008","journal-title":"J. Pathol."},{"issue":"11","key":"10.1016\/j.cyto.2019.154931_b0110","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1111\/j.1365-3024.2009.01157.x","article-title":"Schistosomiasis and liver fibrosis","volume":"31","author":"Andrade","year":"2009","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.cyto.2019.154931_b0115","doi-asserted-by":"crossref","first-page":"6406","DOI":"10.4049\/jimmunol.164.12.6406","article-title":"IL-10 and the dangers of immune polarization: excessive type 1 and type 2 cytokine responses induce distinct forms of lethal immunopathology in murine schistosomiasis","volume":"164","author":"Hoffmann","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.cyto.2019.154931_b0120","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.pt.2013.12.009","article-title":"Cellular and chemokine-mediated regulation in schistosome-induced hepatic pathology","volume":"30","author":"Chuah","year":"2014","journal-title":"Trend Parasitol."},{"issue":"2","key":"10.1016\/j.cyto.2019.154931_b0125","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/s00436-002-0719-z","article-title":"A method to obtain axenic Angiostrongylus vasorum first-stage larvae from dog feces","volume":"89","author":"Bar\u00e7ante","year":"2003","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.cyto.2019.154931_b0130","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1365-3024.2007.01009.x","article-title":"Evaluation of the immune response against Strongyloides venezuelensis in antigen-immunized or previously infected mice","volume":"30","author":"Fernandes","year":"2008","journal-title":"Parasite Immunol."},{"issue":"3","key":"10.1016\/j.cyto.2019.154931_b0135","first-page":"500","article-title":"New criterion for interpretation of the intradermal reaction in schistosomiasis","volume":"8","author":"Pellegrino","year":"1956","journal-title":"Revista Brasileira De Malariologia e Doen\u00e7as Tropicais"},{"key":"10.1016\/j.cyto.2019.154931_b0140","first-page":"589","article-title":"A perfusion technic for recovery of Schistosoma mansoni from experimentally infected guinea pigs","volume":"8","author":"Pellegrino","year":"1956","journal-title":"Revista Brasileira de Malariologia e Doen\u00e7as Tropical"},{"issue":"2","key":"10.1016\/j.cyto.2019.154931_b0145","first-page":"328","article-title":"Conditions affecting the accuracy of potassium hydroxide Digestion techniques for counting Schistosoma mansoni eggs in tissues","volume":"39","author":"Cheever","year":"1968","journal-title":"Bull World Health Organ"},{"issue":"2","key":"10.1016\/j.cyto.2019.154931_b0150","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/0022-1759(85)90242-X","article-title":"Detection of eosinophils using an eosinophil peroxidase assay. Its use as an assay for eosinophil differentiation factors","volume":"83","author":"Strath","year":"1985","journal-title":"J. Immunol. Methods"},{"issue":"6","key":"10.1016\/j.cyto.2019.154931_b0155","doi-asserted-by":"crossref","first-page":"2720","DOI":"10.1172\/JCI117974","article-title":"Neutrophil chemoattractants generated in two phases during reperfusion of ischemic myocardium in the rabbit. Evidence for a role for C5a and interleukin-8","volume":"95","author":"Ivey","year":"1995","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.cyto.2019.154931_b0160","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/BF00914166","article-title":"Induction of cell infiltration and acid hydrolase release into the peritoneal cavity of mice","volume":"4","author":"Green","year":"1980","journal-title":"Inflammation"},{"issue":"2","key":"10.1016\/j.cyto.2019.154931_b0165","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1189\/jlb.1104682","article-title":"Impaired inflammatory angiogenesis, but not leukocyte influx, in mice lacking TNFR1","volume":"78","author":"Barcelos","year":"2005","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.cyto.2019.154931_b0170","doi-asserted-by":"crossref","first-page":"6533","DOI":"10.4049\/jimmunol.167.11.6533","article-title":"Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1\/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism","volume":"167","author":"Hesse","year":"2001","journal-title":"J. Immunol."},{"issue":"66","key":"10.1016\/j.cyto.2019.154931_b0175","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.niox.2017.02.013","article-title":"S. mansoni-T. cruzi co-infection modulates arginase-1\/iNOS expression, liver and heart disease in mice","volume":"1","author":"Rodrigues","year":"2017","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.cyto.2019.154931_b0180","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.jchromb.2006.07.054","article-title":"Analysis of nitrite and nitrate in biological fluids by assays based on the Griess reaction: appraisal of the Griess reaction in the L-arginine\/nitric oxide area of research","volume":"15","author":"Tsikas","year":"2007","journal-title":"J. Chromatogr., B: Anal. Technol. Biomed. Life Sci."},{"issue":"3","key":"10.1016\/j.cyto.2019.154931_b0185","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/0009-9120(96)00003-6","article-title":"A simplified method for the analysis of hydroxyproline in biological tissues","volume":"29","author":"Reddy","year":"1996","journal-title":"Clin. Biochem."},{"issue":"1","key":"10.1016\/j.cyto.2019.154931_b0190","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1093\/ajcp\/28.1.56","article-title":"A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases","volume":"28","author":"Reitman","year":"1957","journal-title":"Am. J. Clin. Pathol."},{"key":"10.1016\/j.cyto.2019.154931_b0195","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1016\/S0140-6736(06)69440-3","article-title":"Human schistosomiasis","volume":"368","author":"Gryseels","year":"2006","journal-title":"The Lancet"},{"key":"10.1016\/j.cyto.2019.154931_b0200","doi-asserted-by":"crossref","first-page":"e2288","DOI":"10.1371\/journal.pntd.0002288","article-title":"Strongyloides stercoralis: Global Distribution and Risk Factors","volume":"7","author":"Schar","year":"2013","journal-title":"PLoS Negl.Trop. Dis."},{"key":"10.1016\/j.cyto.2019.154931_b0205","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1111\/j.0141-9838.2004.00726.x","article-title":"Epidemiological and clinical interaction between HTLV-1 and Strongyloides stercoralis","volume":"26","author":"Carvalho","year":"2004","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.cyto.2019.154931_b0210","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1097\/01.mcg.0000152779.68900.33","article-title":"Intestinal strongyloidiasis: recognition, management, and determinants of outcome","volume":"39","author":"Concha","year":"2005","journal-title":"J. Clin. Gastroenterol."},{"key":"10.1016\/j.cyto.2019.154931_b0215","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.0105-2896.2006.00409.x","article-title":"Natural regulatory T cells and parasites: a common quest for host homeostasis","volume":"212","author":"Belkaid","year":"2006","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.cyto.2019.154931_b0220","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/B978-0-12-391429-3.00005-8","article-title":"Coinfection of Schistosoma (Trematoda) with bacteria, protozoa and helminthes","volume":"77","author":"Abruzzi","year":"2011","journal-title":"Adv. Parasitol."},{"key":"10.1016\/j.cyto.2019.154931_b0225","doi-asserted-by":"crossref","unstructured":"K. Tzanetou, P. Tsiodra, K. Frangia, E. Karakatsani, A. Efstratopoulos, V. Syriopoulos, Coinfection of S. mansoni and Strongyloides in patient with variceal bleeding, Infection 33(4) (2005) 292\u2013294.","DOI":"10.1007\/s15010-005-4098-0"},{"issue":"4","key":"10.1016\/j.cyto.2019.154931_b0230","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1186\/1756-3305-4-232","article-title":"Integrated prevalence mapping of schistosomiasis, soil-transmitted helminthiasis and malaria in lakeside and island communities in Lake Victoria, Uganda","volume":"13","author":"Kabatereine","year":"2011","journal-title":"Parasites & Vectors"},{"key":"10.1016\/j.cyto.2019.154931_b0235","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/0035-9203(86)90301-9","article-title":"Does ancylostomiasis favor the intensity of Schistosoma mansoni infection","volume":"80","author":"Chamone","year":"1986","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.cyto.2019.154931_b0240","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.1365-3156.2005.01541.x","article-title":"Synergistic associations between hookworm and other helminth species in rural community in Brazil","volume":"11","author":"Fleming","year":"2006","journal-title":"Trop. Med. Int. Health"},{"issue":"6","key":"10.1016\/j.cyto.2019.154931_b0245","doi-asserted-by":"crossref","first-page":"e245","DOI":"10.1371\/journal.pntd.0000245","article-title":"The synergistic effect of concomitant schistosomiasis, hookworm, and Trichuris infections on children's anemia burden","volume":"2","author":"Ezeamama","year":"2008","journal-title":"PLoS Negl.Trop. Dis."},{"issue":"Pt B","key":"10.1016\/j.cyto.2019.154931_b0250","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.actatropica.2014.09.016","article-title":"Epidemiology of Strongyloides stercoralis on Mekong islands in southern Laos","volume":"141","author":"Vonghachack","year":"2015","journal-title":"Acta Trop."},{"issue":"11","key":"10.1016\/j.cyto.2019.154931_b0260","doi-asserted-by":"crossref","first-page":"5164","DOI":"10.1128\/IAI.00673-08","article-title":"Coinfection with the intestinal nematode Heligmosomoides polygyrus markedly reduces hepatic egg-induced immunopathology and proinflammatory cytokines in mouse models of severe schistosomiasis","volume":"76","author":"Bazzone","year":"2008","journal-title":"Infect. Immun."},{"key":"10.1016\/j.cyto.2019.154931_b0265","first-page":"17","article-title":"Unchanged susceptibility of jird (Meriones unguiculatus) with existing Brugia pahangi infection to Schistosoma mansoni infection","volume":"31","author":"Sato","year":"1989","journal-title":"Tropical Medicine (Nagaski)"},{"issue":"12","key":"10.1016\/j.cyto.2019.154931_b0270","doi-asserted-by":"crossref","first-page":"5802","DOI":"10.1128\/IAI.00827-08","article-title":"Chronic intestinal nematode infection exacerbates experimental Schistosoma mansoni infection","volume":"76","author":"Bickle","year":"2008","journal-title":"Infect. Immun."},{"issue":"5","key":"10.1016\/j.cyto.2019.154931_b0275","doi-asserted-by":"crossref","first-page":"2303","DOI":"10.4049\/jimmunol.164.5.2303","article-title":"Stat6 regulation of in vivo IL-4 responses","volume":"164","author":"Finkelman","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.cyto.2019.154931_b0280","doi-asserted-by":"crossref","first-page":"13243","DOI":"10.1073\/pnas.231258498","article-title":"Th1-polarizing immunization with egg antigens correlates with severe exacerbation of immunopathology and death in schistosome infection","volume":"98","author":"Rutitzky","year":"2011","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.cyto.2019.154931_b0285","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/j.0105-2896.2004.00197.x","article-title":"The immunobiology of Th1 polarization in high-pathology schistosomiasis","volume":"201","author":"Stadecker","year":"2004","journal-title":"Immunol. Rev."},{"issue":"5","key":"10.1016\/j.cyto.2019.154931_b0290","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.2353\/ajpath.2006.060346","article-title":"TH1-dominant granulomatous pathology does not inhibit fibrosis or cause lethality during murine schistosomiasis","volume":"169","author":"Leeto","year":"2006","journal-title":"Am. J. Pathol."},{"issue":"3","key":"10.1016\/j.cyto.2019.154931_b0295","doi-asserted-by":"crossref","first-page":"e0173456","DOI":"10.1371\/journal.pone.0173456","article-title":"Fasciola hepatica reinfection potentiates a mixed Th1\/Th2\/Th17\/Treg response and correlates with the clinical phenotypes of anemia","volume":"12","author":"Valero","year":"2017","journal-title":"PLoS ONE"},{"key":"10.1016\/j.cyto.2019.154931_b0300","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1038\/nri1412","article-title":"Fibrotic disease and the TH1\/TH2 paradigm","volume":"4","author":"Wynn","year":"2004","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.cyto.2019.154931_b0305","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1038\/sj.icb.7100014","article-title":"Immunopatology of schistosomiasis","volume":"85","author":"Wilson","year":"2007","journal-title":"Immunol. Cell Biol."}],"container-title":["Cytokine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043466619303606?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043466619303606?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T20:53:57Z","timestamp":1760907237000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1043466619303606"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":60,"alternative-id":["S1043466619303606"],"URL":"https:\/\/doi.org\/10.1016\/j.cyto.2019.154931","relation":{},"ISSN":["1043-4666"],"issn-type":[{"type":"print","value":"1043-4666"}],"subject":[],"published":{"date-parts":[[2020,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Strongyloides venezuelensis-infection alters the profile of cytokines and liver inflammation in mice co-infected with Schistosoma mansoni","name":"articletitle","label":"Article Title"},{"value":"Cytokine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cyto.2019.154931","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"154931"}}