{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T01:08:11Z","timestamp":1780708091220,"version":"3.54.1"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cytokine"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.cyto.2020.155397","type":"journal-article","created":{"date-parts":[[2020,12,17]],"date-time":"2020-12-17T07:05:24Z","timestamp":1608188724000},"page":"155397","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["Suppression of lncRNA MALAT1 reduces pro-inflammatory cytokines production by regulating miR-150-5p\/ZBTB4 axis through JAK\/STAT signal pathway in systemic juvenile idiopathic arthritis"],"prefix":"10.1016","volume":"138","author":[{"given":"Hongjie","family":"Jiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingzhe","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.cyto.2020.155397_b0005","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1136\/annrheumdis-2019-216030","article-title":"Adenosine deaminase 2 as a biomarker of macrophage activation syndrome in systemic juvenile idiopathic arthritis","volume":"79","author":"Lee","year":"2020","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.cyto.2020.155397_b0010","doi-asserted-by":"crossref","unstructured":"T. Beukelman, Treatment advances in systemic juvenile idiopathic arthritis, F1000prime reports 6 (2014) 21.","DOI":"10.12703\/P6-21"},{"issue":"8","key":"10.1016\/j.cyto.2020.155397_b0015","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.autrev.2011.02.001","article-title":"The pathogenesis of oligoarticular\/polyarticular vs systemic juvenile idiopathic arthritis","volume":"10","author":"Lin","year":"2011","journal-title":"Autoimmun. Rev."},{"issue":"10","key":"10.1016\/j.cyto.2020.155397_b0020","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1136\/annrheumdis-2019-215211","article-title":"Development and initial validation of the MS score for diagnosis of macrophage activation syndrome in systemic juvenile idiopathic arthritis","volume":"78","author":"Minoia","year":"2019","journal-title":"Ann. Rheum. Dis."},{"issue":"9","key":"10.1016\/j.cyto.2020.155397_b0025","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1002\/eji.201546092","article-title":"Understanding inflammation in juvenile idiopathic arthritis: How immune biomarkers guide clinical strategies in the systemic onset subtype","volume":"46","author":"Swart","year":"2016","journal-title":"Eur. J. Immunol."},{"issue":"6","key":"10.1016\/j.cyto.2020.155397_b0030","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1016\/j.cell.2013.02.012","article-title":"Long noncoding RNAs: cellular address codes in development and disease","volume":"152","author":"Batista","year":"2013","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.cyto.2020.155397_b0035","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.tibs.2013.10.002","article-title":"Long noncoding RNAs: fresh perspectives into the RNA world","volume":"39","author":"Yang","year":"2014","journal-title":"Trends Biochem. Sci."},{"issue":"2","key":"10.1016\/j.cyto.2020.155397_b0040","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1109\/TCBB.2017.2701379","article-title":"Integrating multiple heterogeneous networks for novel LncRNA-disease association inference","volume":"16","author":"Zhang","year":"2019","journal-title":"IEEE\/ACM Trans. Computational Biol. Bioinformatics"},{"issue":"3","key":"10.1016\/j.cyto.2020.155397_b0045","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.cell.2018.01.011","article-title":"Functional classification and experimental dissection of long noncoding RNAs","volume":"172","author":"Kopp","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.cyto.2020.155397_b0050","doi-asserted-by":"crossref","first-page":"110507","DOI":"10.1016\/j.biopha.2020.110507","article-title":"The crucial role of non-coding RNAs in the pathophysiology of inflammatory bowel disease","volume":"129","author":"Ghafouri-Fard","year":"2020","journal-title":"Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie"},{"issue":"2","key":"10.1016\/j.cyto.2020.155397_b0055","doi-asserted-by":"crossref","first-page":"112136","DOI":"10.1016\/j.yexcr.2020.112136","article-title":"Inhibiting role of long non-coding RNA LINC01197 in inflammation in rheumatoid arthritis through the microRNA-150\/THBS2 axis","volume":"394","author":"Zhao","year":"2020","journal-title":"Exp. Cell Res."},{"issue":"3","key":"10.1016\/j.cyto.2020.155397_b0060","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1007\/s10753-020-01189-x","article-title":"Long non-coding RNA THRIL mediates cell growth and inflammatory response of fibroblast-like synoviocytes by activating PI3K\/AKT signals in rheumatoid arthritis","volume":"43","author":"Liang","year":"2020","journal-title":"Inflammation"},{"key":"10.1016\/j.cyto.2020.155397_b0065","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.jaut.2016.07.012","article-title":"Identification of the long noncoding RNA NEAT1 as a novel inflammatory regulator acting through MAPK pathway in human lupus","volume":"75","author":"Zhang","year":"2016","journal-title":"J. Autoimmun."},{"issue":"1","key":"10.1016\/j.cyto.2020.155397_b0070","doi-asserted-by":"crossref","first-page":"188316","DOI":"10.1016\/j.bbcan.2019.188316","article-title":"Long non-coding RNAs and nuclear factor-\u03baB crosstalk in cancer and other human diseases","volume":"1873","author":"Gupta","year":"2020","journal-title":"Biochim. Biophys. Acta, Rev. Cancer"},{"issue":"11","key":"10.1016\/j.cyto.2020.155397_b0075","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.3349\/ymj.2019.60.11.1081","article-title":"LncRNA MALAT1\/MiR-145 adjusts IL-1\u03b2-induced chondrocytes viability and cartilage matrix degradation by regulating ADAMTS5 in human osteoarthritis","volume":"60","author":"Liu","year":"2019","journal-title":"Yonsei Med. J."},{"issue":"5","key":"10.1016\/j.cyto.2020.155397_b0080","doi-asserted-by":"crossref","first-page":"6070","DOI":"10.1096\/fj.201902280R","article-title":"Long noncoding RNA MALAT1 contributes to pregnancy-induced hypertension development by enhancing oxidative stress and inflammation through the regulation of the miR-150-5p\/ET-1 axis","volume":"34","author":"Ou","year":"2020","journal-title":"FASEB J. Off. Publ. Federation Am. Soc. Exp. Biol."},{"issue":"11","key":"10.1016\/j.cyto.2020.155397_b0085","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1038\/nrd4140","article-title":"MicroRNAs and other non-coding RNAs as targets for anticancer drug development","volume":"12","author":"Ling","year":"2013","journal-title":"Nat. Rev. Drug Discovery"},{"key":"10.1016\/j.cyto.2020.155397_b0090","first-page":"271","article-title":"Analyzing MiRNA-LncRNA Interactions, Methods in molecular biology (Clifton","volume":"1402","author":"Paraskevopoulou","year":"2016","journal-title":"N.J.)"},{"key":"10.1016\/j.cyto.2020.155397_b0095","doi-asserted-by":"crossref","first-page":"3023186","DOI":"10.1155\/2020\/3023186","article-title":"Overexpression of miR-150-5p alleviates apoptosis in sepsis-induced myocardial depression","volume":"2020","author":"Zhu","year":"2020","journal-title":"Biomed Res. Int."},{"key":"10.1016\/j.cyto.2020.155397_b0100","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.placenta.2020.02.019","article-title":"miR-150-5p mediates extravillous trophoblast cell migration and angiogenesis functions by regulating VEGF and MMP9","volume":"93","author":"Zeng","year":"2020","journal-title":"Placenta"},{"issue":"7","key":"10.1016\/j.cyto.2020.155397_b0105","first-page":"3882","article-title":"Effects of miR-150-5p on cerebral infarction rats by regulating the Wnt signaling pathway via p53","volume":"24","author":"Sun","year":"2020","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"9","key":"10.1016\/j.cyto.2020.155397_b0110","first-page":"3311","article-title":"Long noncoding RNA MALAT1 modulates sepsis-induced cardiac inflammation through the miR-150-5p\/NF-\u03baB axis","volume":"12","author":"Wei","year":"2019","journal-title":"Int. J. Clin. Exp. Path."},{"issue":"8","key":"10.1016\/j.cyto.2020.155397_b0115","doi-asserted-by":"crossref","first-page":"6570","DOI":"10.18632\/aging.102953","article-title":"Long non-coding RNA MALAT1 exacerbates acute respiratory distress syndrome by upregulating ICAM-1 expression via microRNA-150-5p downregulation","volume":"12","author":"Yao","year":"2020","journal-title":"Aging"},{"key":"10.1016\/j.cyto.2020.155397_b0120","doi-asserted-by":"crossref","unstructured":"J. Tibaldi, A. Pistorio, E. Aldera, L. Puzone, Y. El Miedany, P. Pal, P.P. Giri, H. De, R. Khubchandani, P.P. Chavan, S. Vilaiyuk, B. Lerkvaleekul, J. Yamsuwan, T.K. Sabui, P. Datta, M. Pardeo, C. Bracaglia, S. Sawhney, S. Mittal, W.A. Hassan, G.F. Elderiny, M.H. Abu-Zaid, M. Eissa, F. Sztajnbok, F.C. das Neves Sztajnbok, R. Russo, M.M. Katsicas, R. Cimaz, E. Marrani, E. Alexeeva, T.M. Dvoryakovskaya, M.O. Alsuweiti, R.M. Alzyoud, M. Kostik, I. Chikova, F. Minoia, G. Filocamo, Y. Farag, H. Lotfy, S.I. Nasef, S.M. Al-Mayouf, M.C. Maggio, C.S. Magalhaes, R. Gallizzi, G. Conti, M. Shimizu, A. Civino, E. Felici, G. Giancane, N. Ruperto, A. Consolaro, A. Ravelli, Development and initial validation of a composite disease activity score for systemic juvenile idiopathic arthritis, Rheumatology (Oxford, England) (2020).","DOI":"10.1093\/rheumatology\/keaa240"},{"issue":"8","key":"10.1016\/j.cyto.2020.155397_b0125","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1016\/j.autrev.2015.04.007","article-title":"Juvenile idiopathic arthritis and physical activity: possible inflammatory and immune modulation and tracks for interventions in young populations","volume":"14","author":"Rochette","year":"2015","journal-title":"Autoimmun. Rev."},{"issue":"5","key":"10.1016\/j.cyto.2020.155397_b0130","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1136\/annrheumdis-2016-210324","article-title":"Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications","volume":"76","author":"Ombrello","year":"2017","journal-title":"Ann. Rheum. Dis."},{"issue":"7","key":"10.1016\/j.cyto.2020.155397_b0135","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1038\/nrrheum.2011.68","article-title":"Pathogenesis of systemic juvenile idiopathic arthritis: some answers, more questions","volume":"7","author":"Mellins","year":"2011","journal-title":"Nat. Rev. Rheumatol."},{"issue":"1","key":"10.1016\/j.cyto.2020.155397_b0140","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.cytogfr.2014.05.005","article-title":"Cytokine balance and cytokine-driven natural killer cell dysfunction in systemic juvenile idiopathic arthritis","volume":"26","author":"Avau","year":"2015","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.cyto.2020.155397_b0145","doi-asserted-by":"crossref","unstructured":"T.H. Mogensen, Pathogen recognition and inflammatory signaling in innate immune defenses, Clin. Microbiol. Rev. 22(2) (2009) 240-73, Table of Contents.","DOI":"10.1128\/CMR.00046-08"},{"issue":"3","key":"10.1016\/j.cyto.2020.155397_b0150","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1002\/cre2.69","article-title":"Hydrogen sulfide exposure induces NLRP3 inflammasome-dependent IL-1\u03b2 and IL-18 secretion in human mononuclear leukocytes in vitro","volume":"3","author":"Basic","year":"2017","journal-title":"Clin. Exp. Dental Res."},{"issue":"1","key":"10.1016\/j.cyto.2020.155397_b0155","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1186\/s12967-018-1655-8","article-title":"Plasma interleukin-37 is increased and inhibits the production of inflammatory cytokines in peripheral blood mononuclear cells in systemic juvenile idiopathic arthritis patients","volume":"16","author":"Feng","year":"2018","journal-title":"J. Translational Med."},{"issue":"1","key":"10.1016\/j.cyto.2020.155397_b0160","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s13075-016-1212-x","article-title":"Early changes in gene expression and inflammatory proteins in systemic juvenile idiopathic arthritis patients on canakinumab therapy","volume":"19","author":"Brachat","year":"2017","journal-title":"Arthritis Res. Therapy"},{"issue":"1","key":"10.1016\/j.cyto.2020.155397_b0165","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1038\/s41590-019-0559-y","article-title":"T cells instruct myeloid cells to produce inflammasome-independent IL-1\u03b2 and cause autoimmunity","volume":"21","author":"Jain","year":"2020","journal-title":"Nat. Immunol."},{"issue":"4","key":"10.1016\/j.cyto.2020.155397_b0170","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/j.immuni.2019.03.026","article-title":"Targeting interleukin-6 signaling in clinic","volume":"50","author":"Kang","year":"2019","journal-title":"Immunity"},{"key":"10.1016\/j.cyto.2020.155397_b0175","doi-asserted-by":"crossref","unstructured":"A. Cutando, J. Montero, R. G\u00f3mez-de Diego, M.J. Ferrera, A. Lopez-Valverde, Effect of topical application of melatonin on serum levels of C-reactive protein (CRP), interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-\u03b1) in patients with type 1 or type 2 diabetes and periodontal disease, Journal of clinical and experimental dentistry 7(5) (2015) e628-33.","DOI":"10.4317\/jced.52604"},{"key":"10.1016\/j.cyto.2020.155397_b0180","doi-asserted-by":"crossref","unstructured":"A.J. Hueber, D.L. Asquith, A.M. Miller, J. Reilly, S. Kerr, J. Leipe, A.J. Melendez, I.B. McInnes, Mast cells express IL-17A in rheumatoid arthritis synovium, Journal of immunology (Baltimore, Md. : 1950) 184(7) (2010) 3336-40.","DOI":"10.4049\/jimmunol.0903566"},{"issue":"4","key":"10.1016\/j.cyto.2020.155397_b0185","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1136\/gutjnl-2012-303252","article-title":"Collagen degradation and neutrophilic infiltration: a vicious circle in inflammatory bowel disease","volume":"63","author":"Koelink","year":"2014","journal-title":"Gut"},{"issue":"8","key":"10.1016\/j.cyto.2020.155397_b0190","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1161\/CIRCRESAHA.118.314438","article-title":"Protective effects of activated myofibroblasts in the pressure-overloaded myocardium are mediated through Smad-dependent activation of a matrix-preserving program","volume":"124","author":"Russo","year":"2019","journal-title":"Circ. Res."},{"issue":"9","key":"10.1016\/j.cyto.2020.155397_b0195","first-page":"1481","article-title":"Proinflammatory cytokines in monitoring the course of disease and effectiveness of treatment with etanercept (ETN) of children with oligo- and polyarticular juvenile idiopathic arthritis (JIA)","volume":"60","author":"Kaminiarczyk-Pyzalka","year":"2014","journal-title":"Clin. Lab."},{"issue":"6","key":"10.1016\/j.cyto.2020.155397_b0200","doi-asserted-by":"crossref","first-page":"7120","DOI":"10.18632\/oncotarget.6859","article-title":"Identifying and functionally characterizing tissue-specific and ubiquitously expressed human lncRNAs","volume":"7","author":"Jiang","year":"2016","journal-title":"Oncotarget"},{"issue":"1","key":"10.1016\/j.cyto.2020.155397_b0205","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.gene.2016.08.012","article-title":"LncRNAs expression in adjuvant-induced arthritis rats reveals the potential role of LncRNAs contributing to rheumatoid arthritis pathogenesis","volume":"593","author":"Jiang","year":"2016","journal-title":"Gene"},{"issue":"1","key":"10.1016\/j.cyto.2020.155397_b0210","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1186\/s13075-016-1129-4","article-title":"Long noncoding RNA expression profile in fibroblast-like synoviocytes from patients with rheumatoid arthritis","volume":"18","author":"Zhang","year":"2016","journal-title":"Arthritis Res. Therapy"},{"key":"10.1016\/j.cyto.2020.155397_b0215","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.intimp.2017.06.021","article-title":"LncRNA HOTAIR alleviates rheumatoid arthritis by targeting miR-138 and inactivating NF-\u03baB pathway","volume":"50","author":"Zhang","year":"2017","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.cyto.2020.155397_b0220","doi-asserted-by":"crossref","unstructured":"S. Carpenter, D. Aiello, M.K. Atianand, E.P. Ricci, P. Gandhi, L.L. Hall, M. Byron, B. Monks, M. Henry-Bezy, J.B. Lawrence, L.A. O'Neill, M.J. Moore, D.R. Caffrey, K.A. Fitzgerald, A long noncoding RNA mediates both activation and repression of immune response genes, Science (New York, N.Y.) 341(6147) (2013) 789-92.","DOI":"10.1126\/science.1240925"},{"key":"10.1016\/j.cyto.2020.155397_b0225","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.intimp.2017.11.038","article-title":"LncRNA MALAT1 regulates sepsis-induced cardiac inflammation and dysfunction via interaction with miR-125b and p38 MAPK\/NF\u03baB","volume":"55","author":"Chen","year":"2018","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.cyto.2020.155397_b0230","doi-asserted-by":"crossref","first-page":"8245810","DOI":"10.1155\/2019\/8245810","article-title":"LncRNA MALAT1 suppression protects endothelium against oxLDL-induced inflammation via inhibiting expression of MiR-181b target gene TOX","volume":"2019","author":"Wang","year":"2019","journal-title":"Oxid. Med. Cell. Longevity"},{"key":"10.1016\/j.cyto.2020.155397_b0235","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.molimm.2019.04.015","article-title":"LncRNA MALAT1 cessation antagonizes hypoxia\/reoxygenation injury in hepatocytes by inhibiting apoptosis and inflammation via the HMGB1-TLR4 axis","volume":"112","author":"Zhang","year":"2019","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.cyto.2020.155397_b0240","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.intimp.2018.10.007","article-title":"Contribution of IL-1\u03b2, 6 and TNF-\u03b1 to the form of post-traumatic osteoarthritis induced by \u201cidealized\u201d anterior cruciate ligament reconstruction in a porcine model","volume":"65","author":"Han","year":"2018","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.cyto.2020.155397_b0245","doi-asserted-by":"crossref","first-page":"2363460","DOI":"10.1155\/2019\/2363460","article-title":"Exploring the involvement of NLRP3 and IL-1\u03b2 in osteoarthritis of the hand: results from a pilot study","volume":"2019","author":"Fioravanti","year":"2019","journal-title":"Mediators Inflamm."},{"key":"10.1016\/j.cyto.2020.155397_b0250","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.3389\/fimmu.2019.02218","article-title":"Long non-coding RNA HIX003209 promotes inflammation by sponging miR-6089 via TLR4\/NF-\u03baB signaling pathway in rheumatoid arthritis","volume":"10","author":"Yan","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.cyto.2020.155397_b0255","doi-asserted-by":"crossref","first-page":"118095","DOI":"10.1016\/j.lfs.2020.118095","article-title":"LncRNA LOXL1-AS1 is transcriptionally activated by JUND and contributes to osteoarthritis progression via targeting the miR-423-5p\/KDM5C axis","volume":"258","author":"Chen","year":"2020","journal-title":"Life Sci."},{"key":"10.1016\/j.cyto.2020.155397_b0260","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.imlet.2020.08.001","article-title":"LncRNA GAS5 suppresses CD4(+) T cell activation by upregulating E4BP4 via inhibiting miR-92a-3p in systemic lupus erythematosus","volume":"227","author":"Liu","year":"2020","journal-title":"Immunol. Lett."},{"issue":"11\u201312","key":"10.1016\/j.cyto.2020.155397_b0265","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1007\/s10495-018-1474-7","article-title":"MiRNA-126 expression inhibits IL-23R mediated TNF-\u03b1 or IFN-\u03b3 production in fibroblast-like synoviocytes in a mice model of collagen-induced rheumatoid arthritis","volume":"23","author":"Gao","year":"2018","journal-title":"Apoptosis: Int. J. Programmed Cell Death"},{"key":"10.1016\/j.cyto.2020.155397_b0270","doi-asserted-by":"crossref","first-page":"105839","DOI":"10.1016\/j.intimp.2019.105839","article-title":"MicroRNA-27a alleviates IL-1\u03b2-induced inflammatory response and articular cartilage degradation via TLR4\/NF-\u03baB signaling pathway in articular chondrocytes","volume":"76","author":"Qiu","year":"2019","journal-title":"Int. Immunopharmacol."},{"issue":"1","key":"10.1016\/j.cyto.2020.155397_b0275","doi-asserted-by":"crossref","first-page":"129731","DOI":"10.1016\/j.bbagen.2020.129731","article-title":"miR146a up-regulation is involved in small HA oligosaccharides-induced pro-inflammatory response in human chondrocytes","volume":"1865","author":"Avenoso","year":"2020","journal-title":"Biochim. Biophys. Acta, Gen. Subj."},{"issue":"2","key":"10.1016\/j.cyto.2020.155397_b0280","doi-asserted-by":"crossref","first-page":"224","DOI":"10.3109\/14397595.2015.1060663","article-title":"Differential plasma microRNAs expression in juvenile idiopathic arthritis","volume":"26","author":"Ma","year":"2016","journal-title":"Mod. Rheumatol."},{"issue":"8","key":"10.1016\/j.cyto.2020.155397_b0285","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/j.autrev.2019.06.006","article-title":"MicroRNAs in juvenile idiopathic arthritis: Can we learn more about pathophysiological mechanisms?","volume":"18","author":"Nziza","year":"2019","journal-title":"Autoimmun. Rev."},{"issue":"8","key":"10.1016\/j.cyto.2020.155397_b0290","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.3899\/jrheum.150593","article-title":"Plasma miR-26a as a diagnostic biomarker regulates cytokine expression in systemic juvenile idiopathic arthritis","volume":"43","author":"Sun","year":"2016","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.cyto.2020.155397_b0295","doi-asserted-by":"crossref","first-page":"580","DOI":"10.3389\/fimmu.2018.00580","article-title":"Regulation of the development and function of B cells by ZBTB transcription factors","volume":"9","author":"Zhu","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.cyto.2020.155397_b0300","doi-asserted-by":"crossref","unstructured":"Y. Yu, R. Shang, Y. Chen, J. Li, Z. Liang, J. Hu, K. Liu, C. Chen, Tumor suppressive ZBTB4 inhibits cell growth by regulating cell cycle progression and apoptosis in Ewing sarcoma, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 100 (2018) 108-115.","DOI":"10.1016\/j.biopha.2018.01.132"},{"key":"10.1016\/j.cyto.2020.155397_b0305","doi-asserted-by":"crossref","unstructured":"E.E. Blue, C.E. Yu, T.A. Thornton, N.H. Chapman, E. Kernfeld, N. Jiang, K.M. Shively, K.J. Buckingham, C.T. Marvin, M.J. Bamshad, T.D. Bird, E.M. Wijsman, Variants regulating ZBTB4 are associated with age-at-onset of Alzheimer's disease, Genes, brain, and behavior 17(6) (2018) e12429.","DOI":"10.1111\/gbb.12429"},{"key":"10.1016\/j.cyto.2020.155397_b0310","doi-asserted-by":"crossref","first-page":"153036","DOI":"10.1016\/j.phymed.2019.153036","article-title":"Genkwanin ameliorates adjuvant-induced arthritis in rats through inhibiting JAK\/STAT and NF-\u03baB signaling pathways","volume":"63","author":"Bao","year":"2019","journal-title":"Phytomedicine: Int. J. Phytotherapy Phytopharmacol."},{"issue":"2","key":"10.1016\/j.cyto.2020.155397_b0315","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1124\/jpet.119.262907","article-title":"Cinnamaldehyde inhibits inflammation of human synoviocyte cells through regulation of Jak\/Stat pathway and ameliorates collagen-induced arthritis in rats","volume":"373","author":"Cheng","year":"2020","journal-title":"J. Pharmacol. Exp. Therapeutics"},{"issue":"5","key":"10.1016\/j.cyto.2020.155397_b0320","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1007\/s12519-019-00268-w","article-title":"Regulation of JAK\/STAT signal pathway by miR-21 in the pathogenesis of juvenile idiopathic arthritis","volume":"16","author":"Li","year":"2020","journal-title":"World J. Pediatrics: WJP"},{"issue":"6","key":"10.1016\/j.cyto.2020.155397_b0325","doi-asserted-by":"crossref","first-page":"2531","DOI":"10.3892\/etm.2016.3188","article-title":"Effect of miR-19a and miR-21 on the JAK\/STAT signaling pathway in the peripheral blood mononuclear cells of patients with systemic juvenile idiopathic arthritis","volume":"11","author":"Li","year":"2016","journal-title":"Exp. Therapeutic Med."}],"container-title":["Cytokine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043466620304130?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043466620304130?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T20:59:07Z","timestamp":1760907547000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1043466620304130"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":65,"alternative-id":["S1043466620304130"],"URL":"https:\/\/doi.org\/10.1016\/j.cyto.2020.155397","relation":{},"ISSN":["1043-4666"],"issn-type":[{"value":"1043-4666","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Suppression of lncRNA MALAT1 reduces pro-inflammatory cytokines production by regulating miR-150-5p\/ZBTB4 axis through JAK\/STAT signal pathway in systemic juvenile idiopathic arthritis","name":"articletitle","label":"Article Title"},{"value":"Cytokine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cyto.2020.155397","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"155397"}}