{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,14]],"date-time":"2026-11-14T02:41:40Z","timestamp":1794624100735,"version":"4.9.1"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cytokine"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.cyto.2021.155440","type":"journal-article","created":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T12:10:48Z","timestamp":1612527048000},"page":"155440","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"special_numbering":"C","title":["Immunological alterations in patients with chronic prostatitis\/chronic pelvic pain syndrome and experimental autoimmune prostatitis model: A systematic review and meta-analysis"],"prefix":"10.1016","volume":"141","author":[{"given":"Lei","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zichen","family":"Bian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jialin","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaozhao","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.cyto.2021.155440_b0005","doi-asserted-by":"crossref","DOI":"10.1177\/1557988320903200","article-title":"Chronic prostatitis\/chronic pelvic pain syndrome: a disease or symptom? Current perspectives on diagnosis, treatment, and prognosis","volume":"14","author":"Zhang","year":"2020","journal-title":"Am. J. Men's Health"},{"issue":"3","key":"10.1016\/j.cyto.2021.155440_b0010","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1001\/jama.282.3.236","article-title":"NIH consensus definition and classification of prostatitis","volume":"282","author":"Krieger","year":"1999","journal-title":"JAMA"},{"issue":"2","key":"10.1016\/j.cyto.2021.155440_b0015","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/fcp.12517","article-title":"Chronic prostatitis\/chronic pelvic pain syndrome and prostate cancer: study of immune cells and cytokines","volume":"34","author":"Liu","year":"2020","journal-title":"Fundam. Clin. Pharmacol."},{"issue":"2","key":"10.1016\/j.cyto.2021.155440_b0020","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1046\/j.1365-2249.2002.01853.x","article-title":"Autoimmune T cell responses to seminal plasma in chronic pelvic pain syndrome (CPPS)","volume":"128","author":"Batstone","year":"2002","journal-title":"Clin. Exp. Immunol."},{"issue":"3","key":"10.1016\/j.cyto.2021.155440_b0025","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.mehy.2008.10.020","article-title":"Chronic prostatitis\/chronic pelvic pain syndrome in males may be an autoimmune disease, potentially responsive to corticosteroid therapy","volume":"72","author":"Tomaskovic","year":"2009","journal-title":"Med. Hypotheses"},{"issue":"5","key":"10.1016\/j.cyto.2021.155440_b0030","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/nrurol.2014.63","article-title":"Immune mediators of chronic pelvic pain syndrome","volume":"11","author":"Murphy","year":"2014","journal-title":"Nat. Rev. Urol."},{"issue":"6","key":"10.1016\/j.cyto.2021.155440_b0035","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1006\/jaut.1998.0248","article-title":"Non-obese diabetic (NOD) mice are genetically susceptible to experimental autoimmune prostatitis (EAP)","volume":"11","author":"Rivero","year":"1998","journal-title":"J. Autoimmun."},{"issue":"2","key":"10.1016\/j.cyto.2021.155440_b0040","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1006\/clim.2002.5281","article-title":"Prostatein or steroid binding protein (PSBP) induces experimental autoimmune prostatitis (EAP) in NOD mice","volume":"105","author":"Rivero","year":"2002","journal-title":"Clin. Immunol. (Orlando, Fla)"},{"issue":"2\u20133","key":"10.1016\/j.cyto.2021.155440_b0045","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.1365-3083.2007.01971.x","article-title":"Autoimmune prostatitis: state of the art","volume":"66","author":"Motrich","year":"2007","journal-title":"Scand. J. Immunol."},{"issue":"1","key":"10.1016\/j.cyto.2021.155440_b0050","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1002\/pros.23252","article-title":"Chronic pelvic pain development and prostate inflammation in strains of mice with different susceptibility to experimental autoimmune prostatitis","volume":"77","author":"Breser","year":"2017","journal-title":"Prostate"},{"issue":"9","key":"10.1016\/j.cyto.2021.155440_b0055","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1007\/s10654-010-9491-z","article-title":"Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses","volume":"25","author":"Stang","year":"2010","journal-title":"Eur. J. Epidemiol."},{"issue":"7109","key":"10.1016\/j.cyto.2021.155440_b0060","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ (Clinical research ed)"},{"issue":"2","key":"10.1016\/j.cyto.2021.155440_b0065","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/j.0006-341X.2000.00455.x","article-title":"Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis","volume":"56","author":"Duval","year":"2000","journal-title":"Biometrics"},{"issue":"7","key":"10.1016\/j.cyto.2021.155440_b0070","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000100","article-title":"The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration","volume":"6","author":"Liberati","year":"2009","journal-title":"PLoS Med."},{"issue":"5","key":"10.1016\/j.cyto.2021.155440_b0075","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1016\/j.juro.2008.01.028","article-title":"Monocyte chemoattractant protein-1 and macrophage inflammatory protein-1alpha as possible biomarkers for the chronic pelvic pain syndrome","volume":"179","author":"Desireddi","year":"2008","journal-title":"J. Urol."},{"issue":"1","key":"10.1016\/j.cyto.2021.155440_b0080","first-page":"63","article-title":"Expression of macrophage inflammatory protein-1alpha in EPS and its significance","volume":"18","author":"Zou","year":"2012","journal-title":"Zhonghua nan ke xue = Natl. J. Androl."},{"issue":"1","key":"10.1016\/j.cyto.2021.155440_b0085","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/S0022-5347(05)67497-6","article-title":"IL-1beta and TNF-alpha in prostatic secretions are indicators in the evaluation of men with chronic prostatitis","volume":"164","author":"Nadler","year":"2000","journal-title":"J. Urol."},{"issue":"11","key":"10.1016\/j.cyto.2021.155440_b0090","first-page":"1035","article-title":"Effects of pollen extract EA-10, P5 on chronic prostatitis or infertility with chronic prostatitis","volume":"23","author":"Chen","year":"2002","journal-title":"Acta Pharmacol. Sin."},{"issue":"10","key":"10.1016\/j.cyto.2021.155440_b0095","first-page":"740","article-title":"IL-8 and TNF-alpha in prostatic secretions as indications in evaluating chronic prostatitis","volume":"10","author":"He","year":"2004","journal-title":"Zhonghua nan ke xue = Natl. J. Androl."},{"issue":"1","key":"10.1016\/j.cyto.2021.155440_b0100","first-page":"25","article-title":"Clinical evaluation of four cytokines in serum and prostatic fluid in chronic abacterial prostatitis","volume":"12","author":"Li","year":"2006","journal-title":"Zhonghua nan ke xue = Natl. J. Androl."},{"issue":"3","key":"10.1016\/j.cyto.2021.155440_b0105","first-page":"245","article-title":"Determination of uric acid in the expressed prostatic secretion of chronic prostatitis patients and its clinical significance","volume":"14","author":"Hou","year":"2008","journal-title":"Zhonghua nan ke xue = Natl. J. Androl."},{"issue":"3","key":"10.1016\/j.cyto.2021.155440_b0110","first-page":"1666","article-title":"The value of neutrophil elastase in diagnosis of type III prostatitis","volume":"11","author":"Zhu","year":"2014","journal-title":"Urol J"},{"issue":"10","key":"10.1016\/j.cyto.2021.155440_b0115","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1007\/s11255-014-0743-9","article-title":"Correlation study of chronic nonbacterial prostatitis with the levels of COX-2 and PGE2 in prostatic secretion","volume":"46","author":"Yuan","year":"2014","journal-title":"Int. Urol. Nephrol."},{"issue":"8","key":"10.1016\/j.cyto.2021.155440_b0120","first-page":"598","article-title":"Effect of chronic abacterial prostatitis on semen quality and efficacy of antibacterial agents","volume":"10","author":"Zhang","year":"2004","journal-title":"Zhonghua nan ke xue = Natl. J. Androl."},{"issue":"5","key":"10.1016\/j.cyto.2021.155440_b0125","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1111\/andr.12386","article-title":"Inflammatory reaction found in prostate-specific material - method standardization and proposed optimal cut-off points","volume":"5","author":"Korrovits","year":"2017","journal-title":"Andrology"},{"issue":"9","key":"10.1016\/j.cyto.2021.155440_b0130","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1046\/j.1442-2042.2001.00358.x","article-title":"Seminal plasma cytokine levels in the diagnosis of chronic pelvic pain syndrome","volume":"8","author":"Orhan","year":"2001","journal-title":"Int. J. Urol."},{"issue":"9","key":"10.1016\/j.cyto.2021.155440_b0135","doi-asserted-by":"crossref","first-page":"2567","DOI":"10.1093\/humrep\/dei073","article-title":"Reduced semen quality in chronic prostatitis patients that have cellular autoimmune response to prostate antigens","volume":"20","author":"Motrich","year":"2005","journal-title":"Hum. Reprod."},{"issue":"5","key":"10.1016\/j.cyto.2021.155440_b0140","doi-asserted-by":"crossref","first-page":"876","DOI":"10.2164\/jandrol.111.014555","article-title":"Chronic pelvic pain syndrome and semen quality of Korean men in their fourth decade","volume":"33","author":"Byun","year":"2012","journal-title":"J. Androl."},{"issue":"1","key":"10.1016\/j.cyto.2021.155440_b0145","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1159\/000479188","article-title":"Clinical evaluation of urine prostatic exosomal protein in the diagnosis of chronic prostatitis","volume":"100","author":"Li","year":"2018","journal-title":"Urol. Int."},{"issue":"6","key":"10.1016\/j.cyto.2021.155440_b0150","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1111\/andr.12273","article-title":"Chronic prostatitis\/chronic pelvic pain syndrome impairs erectile function through increased endothelial dysfunction, oxidative stress, apoptosis, and corporal fibrosis in a rat model","volume":"4","author":"Hu","year":"2016","journal-title":"Andrology"},{"issue":"8","key":"10.1016\/j.cyto.2021.155440_b0155","doi-asserted-by":"crossref","DOI":"10.1111\/and.13302","article-title":"Upregulation of TRPV1 in spinal dorsal root ganglion by activating NGF-TrkA pathway contributes to pelvic organ cross-sensitisation in rats with experimental autoimmune prostatitis","volume":"51","author":"Zhang","year":"2019","journal-title":"Andrologia"},{"issue":"12","key":"10.1016\/j.cyto.2021.155440_b0160","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1002\/pros.23866","article-title":"Effect of alcohol on chronic pelvic pain and prostatic inflammation in a mouse model of experimental autoimmune prostatitis","volume":"79","author":"Zhang","year":"2019","journal-title":"Prostate"},{"issue":"2","key":"10.1016\/j.cyto.2021.155440_b0165","first-page":"211","article-title":"Effects of different Chinese herbal prescriptions on cytokines in au- toimmune prostatitis rats.","volume":"35","author":"Guohong","year":"2015","journal-title":"J. Traditional Chinese Med. = Chung i tsa chih ying wen pan"},{"issue":"11","key":"10.1016\/j.cyto.2021.155440_b0170","first-page":"1018","article-title":"Effect of danpu capsule on inflammatory factors in rat model of autoimmune prostatitis","volume":"28","author":"Li","year":"2008","journal-title":"Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chin. J. Integr. Traditional Western Med."},{"issue":"5","key":"10.1016\/j.cyto.2021.155440_b0175","first-page":"414","article-title":"Establishment of a rat model of autoimmune prostatitis with purified prostatic proteins","volume":"20","author":"Li","year":"2014","journal-title":"Zhonghua nan ke xue = Natl. J. Androl."},{"issue":"4","key":"10.1016\/j.cyto.2021.155440_b0180","first-page":"290","article-title":"Morphological and molecular biological peculiarities of the experimental autoimmune prostatitis rat model","volume":"11","author":"Zhou","year":"2005","journal-title":"Zhonghua nan ke xue = Natl. J. Androl."},{"issue":"5","key":"10.1016\/j.cyto.2021.155440_b0185","first-page":"460","article-title":"Musk and carterii birdw enhance the effect of polygonum extract on chronic non-bacterial prostatitis: an animal experimental study","volume":"18","author":"Zhou","year":"2012","journal-title":"Zhonghua nan ke xue = Natl. J. Androl."},{"issue":"7","key":"10.1016\/j.cyto.2021.155440_b0190","first-page":"602","article-title":"Expressions of SP and NK-1R increase in the posterior horn of the L5\u2013S2 spinal cord in rats with chronic nonbacterial prostatitis","volume":"22","author":"Hao","year":"2016","journal-title":"Zhonghua nan ke xue = Natl. J. Androl."},{"issue":"10","key":"10.1016\/j.cyto.2021.155440_b0195","first-page":"1918","article-title":"Influence of Kudou Shencha decotion on INF-gamma, ICAM-1, MCP-1 levels of prostate tissue homogenate in immunity prostatitis model rats","volume":"39","author":"Xia","year":"2014","journal-title":"Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China J. Chin. Materia Medica"},{"issue":"6","key":"10.1016\/j.cyto.2021.155440_b0200","doi-asserted-by":"crossref","first-page":"521","DOI":"10.3109\/21681805.2013.769460","article-title":"Assessing chronic pelvic pain syndrome patients: blood plasma factors and cortisol saliva","volume":"47","author":"Lundh","year":"2013","journal-title":"Scand. J. Urol."},{"key":"10.1016\/j.cyto.2021.155440_b0205","doi-asserted-by":"crossref","first-page":"28608","DOI":"10.1038\/srep28608","article-title":"The role of inflammatory cytokines and ERK1\/2 signaling in chronic prostatitis\/chronic pelvic pain syndrome with related mental health disorders","volume":"6","author":"Hu","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cyto.2021.155440_b0210","doi-asserted-by":"crossref","DOI":"10.1002\/pros.23684","article-title":"Identification and preliminary study of immunogens involved in autoimmune prostatitis in human males","author":"Lu","year":"2018","journal-title":"Prostate"},{"issue":"20","key":"10.1016\/j.cyto.2021.155440_b0215","first-page":"4185","article-title":"Heat shock protein 9-mediated inflammation reaction in patients with chronic prostatitis with erectile dysfunction","volume":"20","author":"Zhao","year":"2016","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"6","key":"10.1016\/j.cyto.2021.155440_b0220","first-page":"449","article-title":"Clinical evaluation of IL-1beta and TNF-alpha in prostatic secretions for chronic prostatitis","volume":"10","author":"Yang","year":"2004","journal-title":"Zhonghua nan ke xue = Natl. J. Androl."},{"issue":"3","key":"10.1016\/j.cyto.2021.155440_b0225","first-page":"201","article-title":"Analysis of cytokines (IL-2, IL-8, IL-10) in the expressed prostatic secretions of chronic prostatitis","volume":"11","author":"Duan","year":"2005","journal-title":"Zhonghua nan ke xue = Natl. J. Androl."},{"issue":"3","key":"10.1016\/j.cyto.2021.155440_b0230","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.urology.2009.09.061","article-title":"Clinical significance of IL-2, IL-10, and TNF-alpha in prostatic secretion of patients with chronic prostatitis","volume":"75","author":"He","year":"2010","journal-title":"Urology"},{"issue":"1","key":"10.1016\/j.cyto.2021.155440_b0235","first-page":"11","article-title":"Acupuncture for chronic pelvic pain syndromes (CPPS) and its effect on cytokines in prostatic fluid","volume":"31","author":"Yuan","year":"2011","journal-title":"Zhongguo Zhen Jiu"},{"issue":"33","key":"10.1016\/j.cyto.2021.155440_b0240","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000016848","article-title":"The application of IL-10 and TNF-\u03b1 in expressed prostatic secretions and prostatic exosomal protein in urine in the diagnosis of patients with chronic prostatitis","volume":"98","author":"Yin","year":"2019","journal-title":"Medicine (Baltimore)"},{"issue":"4","key":"10.1016\/j.cyto.2021.155440_b0245","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0060987","article-title":"Th1-Th17 cells contribute to the development of uropathogenic Escherichia coli-induced chronic pelvic pain","volume":"8","author":"Quick","year":"2013","journal-title":"PLoS ONE"},{"issue":"3","key":"10.1016\/j.cyto.2021.155440_b0250","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1111\/j.1365-2605.2009.00972.x","article-title":"Chronic inflammation in the pathogenesis of benign prostatic hyperplasia","volume":"33","author":"Fibbi","year":"2010","journal-title":"Int. J. Androl."},{"issue":"2","key":"10.1016\/j.cyto.2021.155440_b0255","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1038\/nm1551","article-title":"A brief history of T(H)17, the first major revision in the T(H)1\/T(H)2 hypothesis of T cell-mediated tissue damage","volume":"13","author":"Steinman","year":"2007","journal-title":"Nat. Med."},{"issue":"4","key":"10.1016\/j.cyto.2021.155440_b0260","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1016\/j.urology.2009.07.1229","article-title":"Characterization of circulating CD4+CD25high regulatory T cells in men with chronic prostatitis\/chronic pelvic pain syndrome","volume":"75","author":"Bai","year":"2010","journal-title":"Urology"},{"issue":"4","key":"10.1016\/j.cyto.2021.155440_b0265","first-page":"pp. 330","article-title":"Detection of peripheral blood Th1\/Th2 cell ratio in patients with chronic abacterial prostatitis\/chronic pelvic pain syndrome","volume":"12","author":"Liu","year":"2006","journal-title":"Zhonghua nan ke xue = Natl. J. Androl."},{"key":"10.1016\/j.cyto.2021.155440_b0270","doi-asserted-by":"crossref","first-page":"898","DOI":"10.3389\/fimmu.2017.00898","article-title":"Immunological mechanisms underlying chronic pelvic pain and prostate inflammation in chronic pelvic pain syndrome","volume":"8","author":"Breser","year":"2017","journal-title":"Front. Immunol."},{"issue":"3","key":"10.1016\/j.cyto.2021.155440_b0275","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1097\/01.ju.0000136002.76898.04","article-title":"Mechanisms in prostatitis\/chronic pelvic pain syndrome","volume":"172","author":"Pontari","year":"2004","journal-title":"J. Urol."},{"issue":"1","key":"10.1016\/j.cyto.2021.155440_b0280","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1038\/s41590-019-0559-y","article-title":"T cells instruct myeloid cells to produce inflammasome-independent IL-1\u03b2 and cause autoimmunity","volume":"21","author":"Jain","year":"2020","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.cyto.2021.155440_b0285","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1146\/annurev-immunol-030409-101212","article-title":"Differentiation of effector CD4 T cell populations (*)","volume":"28","author":"Zhu","year":"2010","journal-title":"Annu. Rev. Immunol."},{"issue":"11","key":"10.1016\/j.cyto.2021.155440_b0290","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1111\/pim.12357","article-title":"Signalling pathways associated with IL-6 production and epithelial-mesenchymal transition induction in prostate epithelial cells stimulated with Trichomonas vaginalis","volume":"38","author":"Han","year":"2016","journal-title":"Parasite Immunol."},{"issue":"1","key":"10.1016\/j.cyto.2021.155440_b0295","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0014-5793(92)80909-Z","article-title":"Interleukin-8, a chemotactic and inflammatory cytokine","volume":"307","author":"Baggiolini","year":"1992","journal-title":"FEBS Lett."},{"issue":"2","key":"10.1016\/j.cyto.2021.155440_b0300","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0192-0561(94)00088-6","article-title":"Interleukin-8 and the chemokine family","volume":"17","author":"Baggiolini","year":"1995","journal-title":"Int. J. Immunopharmacol."},{"issue":"5","key":"10.1016\/j.cyto.2021.155440_b0305","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1586\/1744666X.2014.894886","article-title":"The CXCL8\/IL-8 chemokine family and its receptors in inflammatory diseases","volume":"10","author":"Russo","year":"2014","journal-title":"Expert Rev. Clin. Immunol."},{"issue":"1","key":"10.1016\/j.cyto.2021.155440_b0310","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s40659-019-0237-4","article-title":"Chronic prostatitis alters the prostatic microenvironment and accelerates preneoplastic lesions in C57BL\/6 mice","volume":"52","author":"Gao","year":"2019","journal-title":"Biol. Res."},{"issue":"2","key":"10.1016\/j.cyto.2021.155440_b0315","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.eururo.2006.07.016","article-title":"Seminal plasma cytokines and chemokines in prostate inflammation: interleukin 8 as a predictive biomarker in chronic prostatitis\/chronic pelvic pain syndrome and benign prostatic hyperplasia","volume":"51","author":"Penna","year":"2007","journal-title":"Eur. Urol."}],"container-title":["Cytokine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S104346662100020X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S104346662100020X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T20:59:11Z","timestamp":1760907551000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S104346662100020X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":63,"alternative-id":["S104346662100020X"],"URL":"https:\/\/doi.org\/10.1016\/j.cyto.2021.155440","relation":{},"ISSN":["1043-4666"],"issn-type":[{"value":"1043-4666","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Immunological alterations in patients with chronic prostatitis\/chronic pelvic pain syndrome and experimental autoimmune prostatitis model: A systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Cytokine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cyto.2021.155440","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"155440"}}