{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T22:12:11Z","timestamp":1760911931508,"version":"build-2065373602"},"reference-count":19,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001407","name":"Department of Biotechnology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007338","name":"All-India Institute of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007338","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cytokine"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.cyto.2022.155863","type":"journal-article","created":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T00:50:13Z","timestamp":1648169413000},"page":"155863","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Effect of fetal liver condition media derived cytokines (IL-6 and Flt-3) on human bone marrow stem cells colony formation"],"prefix":"10.1016","volume":"153","author":[{"given":"Rashmi","family":"Bhardwaj","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lalit","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepika","family":"Chhabra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sujata","family":"Mohanty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atul","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.K.","family":"Mehra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vinod","family":"Kochupillai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.cyto.2022.155863_b0005","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1159\/000207558","article-title":"Fetal liver transplantation in aplastic anemia","volume":"62","author":"Kansal","year":"1979","journal-title":"Acta Hem"},{"key":"10.1016\/j.cyto.2022.155863_b0010","first-page":"300","article-title":"Rationale for combined use of fetal liver and thymus for immunological reconstitution in-patient with variants of severe combined immune deficiency","volume":"74","author":"Pahwa","year":"1979","journal-title":"PNAS USA"},{"key":"10.1016\/j.cyto.2022.155863_b0015","first-page":"251","article-title":"Bone marrow reconstitution following human fetal liver infusion (FLI) in sixteen severe aplastic anemia patients","volume":"193","author":"Kochupillai","year":"1985","journal-title":"Prog. Clin. Biol. Res."},{"key":"10.1016\/j.cyto.2022.155863_b0020","first-page":"237","article-title":"Fetal liver transplantation in aplastic anemia and acute leukemia","volume":"193","author":"Izzi","year":"1985","journal-title":"Prog. Clin. Biol. Res."},{"key":"10.1016\/j.cyto.2022.155863_b0025","first-page":"89","article-title":"Fetal liver transplantation in aplastic anemia and leukemia","volume":"12","author":"Gale","year":"1987","journal-title":"Thymus"},{"issue":"suppl 5","key":"10.1016\/j.cyto.2022.155863_b0030","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1111\/j.1600-0609.1991.tb01854.x","article-title":"Hematopoietic improvement after fetal liver infusion in aplastic anemia","volume":"47","author":"Kochupillai","year":"1991","journal-title":"Eur. J. Haematol."},{"key":"10.1016\/j.cyto.2022.155863_b0035","doi-asserted-by":"crossref","first-page":"3500","DOI":"10.1182\/blood.V87.8.3500.bloodjournal8783500","article-title":"The repopulation potential of fetal liver hematopoietic stem cells in mice exceeds that of their liver adult bone marrow counterparts","volume":"87","author":"Rebel","year":"1996","journal-title":"Blood"},{"key":"10.1016\/j.cyto.2022.155863_b0040","doi-asserted-by":"crossref","first-page":"4337","DOI":"10.1182\/blood.V89.12.4337","article-title":"\u2018in vitro\u2019 maintenance of highly purified, transplantable hematopoietic stem cells","volume":"89","author":"Moore","year":"1997","journal-title":"Blood"},{"key":"10.1016\/j.cyto.2022.155863_b0045","first-page":"25","article-title":"Proliferative capacity of human fetal liver hematopoietic cells compared to normal adult bone marrow cells: Potential usage in cellular therapeutics","volume":"8","author":"Raju","year":"1997","journal-title":"Exp. Hematol."},{"key":"10.1016\/j.cyto.2022.155863_b0050","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1016\/S0301-472X(99)00078-8","article-title":"Functional differences between transplantable human hematopoietic stem cells from fetal liver, cord blood, and adult marrow","volume":"27","author":"Holyoake","year":"1999","journal-title":"Exp. Hematol."},{"issue":"suppl 10","key":"10.1016\/j.cyto.2022.155863_b0055","first-page":"1321","article-title":"Maintenance of hematopoiesis in serum-free bone marrow cultures involves sequential recruitment of quiescent progenitors","volume":"21","author":"Lansdorp","year":"1993","journal-title":"Exp. Hematol."},{"issue":"5","key":"10.1016\/j.cyto.2022.155863_b0060","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1089\/152581603322448196","article-title":"Colony stimulating activity of fetal liver cells: Synergistic role of stem cell factor in bone marrow recovery from aplastic anemia","volume":"12","author":"Raju","year":"2003","journal-title":"J. Hematothe Sstem Cell Res."},{"issue":"2","key":"10.1016\/j.cyto.2022.155863_b0065","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1002\/stem.170107","article-title":"Stimulation of adult human bone marrow by factors secreted by fetal liver hematopoietic cells: \u2018in vitro\u2019 evaluation using semisolid clonal assay system","volume":"17","author":"Kale","year":"1999","journal-title":"Stem Cells"},{"issue":"6","key":"10.1016\/j.cyto.2022.155863_b0070","first-page":"247","article-title":"Flt3 Ligand: Role in control of hematopoietic and immune functions of the bone marrow","volume":"18","author":"Wodnar-Filipowicz","year":"2003","journal-title":"News Physiol. Sci."},{"issue":"suppl 11","key":"10.1016\/j.cyto.2022.155863_b0075","doi-asserted-by":"crossref","first-page":"2150","DOI":"10.1182\/blood.V75.11.2150.2150","article-title":"Effects of interleukin-6 on fetal hematopoietic progenitors","volume":"75","author":"Gardner","year":"1990","journal-title":"Blood"},{"issue":"suppl 6","key":"10.1016\/j.cyto.2022.155863_b0080","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1182\/blood.V72.6.2007.2007","article-title":"Synergistic factors for stem cell proliferation: Further studies of the target stem cells and the mechanism of stimulation by interleukin- 1, interleukin-6, and granulocyte colony-stimulating factor","volume":"72","author":"Ikebuchi","year":"1988","journal-title":"Blood"},{"issue":"suppl 6","key":"10.1016\/j.cyto.2022.155863_b0085","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1182\/blood.V71.6.1759.1759","article-title":"Synergism between interleukin-6 and interleukin-3 in supporting proliferation of human hemopoietic stem cells: Comparison with interleukin-1 alpha","volume":"71","author":"Leary","year":"1988","journal-title":"Blood"},{"issue":"suppl 12","key":"10.1016\/j.cyto.2022.155863_b0090","doi-asserted-by":"crossref","first-page":"3196","DOI":"10.1182\/blood.V79.12.3196.bloodjournal79123196","article-title":"Stem cell factor stimulate the \u2018in vitro\u2019 growth of bone marrow cells from aplastic anemia patients","volume":"79","author":"Wodnar-Filipowicz","year":"1992","journal-title":"Blood"},{"issue":"3","key":"10.1016\/j.cyto.2022.155863_b0095","first-page":"146","article-title":"Phenotypic characterization of malignant progenitor cells in patients with idiopathic myelofibrosis","volume":"12","author":"Bao","year":"2019","journal-title":"Hematol"}],"container-title":["Cytokine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043466622000722?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043466622000722?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T21:45:38Z","timestamp":1760910338000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1043466622000722"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":19,"alternative-id":["S1043466622000722"],"URL":"https:\/\/doi.org\/10.1016\/j.cyto.2022.155863","relation":{},"ISSN":["1043-4666"],"issn-type":[{"type":"print","value":"1043-4666"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of fetal liver condition media derived cytokines(IL-6 and Flt-3) on human bone marrow stem cells colony formation","name":"articletitle","label":"Article Title"},{"value":"Cytokine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cyto.2022.155863","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"155863"}}