{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T23:06:53Z","timestamp":1789168013994,"version":"build-2803163510"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T00:00:00Z","timestamp":1767744000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100023670","name":"Nyckelfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100023670","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003170","name":"Knowledge Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003170","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003509","name":"\u00d6rebro University","doi-asserted-by":"publisher","award":["ORU 2022\/07087"],"award-info":[{"award-number":["ORU 2022\/07087"]}],"id":[{"id":"10.13039\/501100003509","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100003077","name":"Knowledge Foundation","doi-asserted-by":"publisher","award":["20160044"],"award-info":[{"award-number":["20160044"]}],"id":[{"id":"10.13039\/100003077","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100003077","name":"Knowledge Foundation","doi-asserted-by":"publisher","award":["20200017"],"award-info":[{"award-number":["20200017"]}],"id":[{"id":"10.13039\/100003077","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009228","name":"Region \u00d6rebro l\u00e4n","doi-asserted-by":"publisher","award":["OLL-972724"],"award-info":[{"award-number":["OLL-972724"]}],"id":[{"id":"10.13039\/501100009228","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009228","name":"Region \u00d6rebro l\u00e4n","doi-asserted-by":"publisher","award":["OLL-935301"],"award-info":[{"award-number":["OLL-935301"]}],"id":[{"id":"10.13039\/501100009228","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009228","name":"Region \u00d6rebro l\u00e4n","doi-asserted-by":"publisher","award":["OLL-880411"],"award-info":[{"award-number":["OLL-880411"]}],"id":[{"id":"10.13039\/501100009228","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009228","name":"Region \u00d6rebro l\u00e4n","doi-asserted-by":"publisher","award":["OLL-986200"],"award-info":[{"award-number":["OLL-986200"]}],"id":[{"id":"10.13039\/501100009228","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009228","name":"Region \u00d6rebro l\u00e4n","doi-asserted-by":"publisher","award":["OLL-960082"],"award-info":[{"award-number":["OLL-960082"]}],"id":[{"id":"10.13039\/501100009228","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cytokine"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.cyto.2026.157107","type":"journal-article","created":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T16:37:50Z","timestamp":1768063070000},"page":"157107","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Inflammatory imbalance in ambulance patients is associated with sepsis and septic shock"],"prefix":"10.1016","volume":"199","author":[{"given":"Kedeye","family":"Tuerxun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Kurland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"S\u00e4rndahl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrika","family":"Wallgren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Eklund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Kruse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.cyto.2026.157107_bb0005","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1186\/s13054-020-02950-2","article-title":"Mortality in sepsis and septic shock in Europe, North America and Australia between 2009 and 2019- results from a systematic review and meta-analysis","volume":"24","author":"Bauer","year":"2020","journal-title":"Crit. Care"},{"issue":"10219","key":"10.1016\/j.cyto.2026.157107_bb0010","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/S0140-6736(19)32989-7","article-title":"Global, regional, and national sepsis incidence and mortality, 1990-2017: analysis for the global burden of disease study","volume":"395","author":"Rudd","year":"2020","journal-title":"Lancet"},{"issue":"8","key":"10.1016\/j.cyto.2026.157107_bb0015","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1001\/jama.2016.0287","article-title":"The third international consensus definitions for Sepsis and septic shock (Sepsis-3)","volume":"315","author":"Singer","year":"2016","journal-title":"JAMA"},{"issue":"8","key":"10.1016\/j.cyto.2026.157107_bb0020","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1001\/jama.2016.0289","article-title":"Developing a new definition and assessing new clinical criteria for septic shock: for the third international consensus definitions for Sepsis and septic shock (Sepsis-3)","volume":"315","author":"Shankar-Hari","year":"2016","journal-title":"JAMA"},{"issue":"23","key":"10.1016\/j.cyto.2026.157107_bb0025","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1056\/NEJMoa1703058","article-title":"Time to treatment and mortality during mandated emergency Care for Sepsis","volume":"376","author":"Seymour","year":"2017","journal-title":"N. Engl. J. Med."},{"issue":"5","key":"10.1016\/j.cyto.2026.157107_bb0030","first-page":"125","article-title":"Impact of the timeliness of antibiotic therapy on the outcome of patients with sepsis and septic shock","volume":"82","author":"Asner","year":"2021","journal-title":"J. Inf. Secur."},{"issue":"7","key":"10.1016\/j.cyto.2026.157107_bb0035","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1038\/nri.2017.36","article-title":"The immunopathology of sepsis and potential therapeutic targets","volume":"17","author":"van der Poll","year":"2017","journal-title":"Nat. Rev. Immunol."},{"issue":"12","key":"10.1016\/j.cyto.2026.157107_bb0040","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1038\/nri3552","article-title":"Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy","volume":"13","author":"Hotchkiss","year":"2013","journal-title":"Nat. Rev. Immunol."},{"issue":"4","key":"10.1016\/j.cyto.2026.157107_bb0045","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1007\/s00134-008-1337-8","article-title":"Increased circulating regulatory T cells (CD4(+)CD25 (+)CD127 (\u2212)) contribute to lymphocyte anergy in septic shock patients","volume":"35","author":"Venet","year":"2009","journal-title":"Intensive Care Med."},{"issue":"11","key":"10.1016\/j.cyto.2026.157107_bb0050","doi-asserted-by":"crossref","first-page":"6952","DOI":"10.4049\/jimmunol.166.11.6952","article-title":"Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans","volume":"166","author":"Hotchkiss","year":"2001","journal-title":"J. Immunol."},{"issue":"2","key":"10.1016\/j.cyto.2026.157107_bb0055","doi-asserted-by":"crossref","first-page":"3649","DOI":"10.18632\/oncotarget.12278","article-title":"On the origin of myeloid-derived suppressor cells","volume":"8","author":"Millrud","year":"2017","journal-title":"Oncotarget"},{"issue":"8","key":"10.1016\/j.cyto.2026.157107_bb0060","article-title":"Evidence for monocyte reprogramming in a long-term Postsepsis study","volume":"4","author":"Gritte","year":"2022","journal-title":"Crit Care Explor."},{"issue":"3","key":"10.1016\/j.cyto.2026.157107_bb0065","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1097\/00024382-200014030-00005","article-title":"Impaired ex vivo lipopolysaccharide-stimulated whole blood tumor necrosis factor production may identify \u201cseptic\u201d intensive care unit patients","volume":"14","author":"Heagy","year":"2000","journal-title":"Shock"},{"issue":"21","key":"10.1016\/j.cyto.2026.157107_bb0070","doi-asserted-by":"crossref","first-page":"12504","DOI":"10.1111\/jcmm.15791","article-title":"Differences in monocyte subsets are associated with short-term survival in patients with septic shock","volume":"24","author":"Hortova-Kohoutkova","year":"2020","journal-title":"J. Cell. Mol. Med."},{"issue":"4","key":"10.1016\/j.cyto.2026.157107_bb0075","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1097\/SLA.0000000000001783","article-title":"Human myeloid-derived suppressor cells are associated with chronic immune Suppression after severe Sepsis\/septic shock","volume":"265","author":"Mathias","year":"2017","journal-title":"Ann. Surg."},{"issue":"5","key":"10.1016\/j.cyto.2026.157107_bb0080","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1186\/cc5055","article-title":"Bench-to-bedside review: endotoxin tolerance as a model of leukocyte reprogramming in sepsis","volume":"10","author":"Cavaillon","year":"2006","journal-title":"Crit. Care"},{"issue":"4","key":"10.1016\/j.cyto.2026.157107_bb0085","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1002\/JLB.3A0421-216R","article-title":"Cytokine responses to LPS in reprogrammed monocytes are associated with the transcription factor PU.1","volume":"112","author":"Tuerxun","year":"2022","journal-title":"J. Leukoc. Biol."},{"issue":"1","key":"10.1016\/j.cyto.2026.157107_bb0090","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s13049-020-00745-6","article-title":"The predictive value of variables measurable in the ambulance and the development of the predict Sepsis screening tools: a prospective cohort study","volume":"28","author":"Wallgren","year":"2020","journal-title":"Scand. J. Trauma Resusc. Emerg. Med."},{"issue":"1","key":"10.1016\/j.cyto.2026.157107_bb0095","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1186\/s12873-022-00746-x","article-title":"Association between variables measured in the ambulance and in-hospital mortality among adult patients with and without infection: a prospective cohort study","volume":"22","author":"Wallgren","year":"2022","journal-title":"BMC Emerg. Med."},{"issue":"5","key":"10.1016\/j.cyto.2026.157107_bb0100","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","article-title":"A new method of classifying prognostic comorbidity in longitudinal studies: development and validation","volume":"40","author":"Charlson","year":"1987","journal-title":"J. Chronic Dis."},{"issue":"20","key":"10.1016\/j.cyto.2026.157107_bb0105","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1001\/jama.2013.281053","article-title":"Ethical principles for medical research involving human subjects","volume":"310","author":"World Medical Association Declaration of Helsinki","year":"2013","journal-title":"JAMA"},{"issue":"1","key":"10.1016\/j.cyto.2026.157107_bb0110","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/01.shk.0000068322.08268.b4","article-title":"Predictive value of monocyte histocompatibility leukocyte antigen-DR expression and plasma interleukin-4 and-10 levels in critically ill patients with sepsis","volume":"20","author":"Hynninen","year":"2003","journal-title":"Shock"},{"issue":"2","key":"10.1016\/j.cyto.2026.157107_bb0115","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.imlet.2004.07.009","article-title":"The anti-inflammatory response dominates after septic shock: association of low monocyte HLA-DR expression and high interleukin-10 concentration","volume":"95","author":"Monneret","year":"2004","journal-title":"Immunol. Lett."},{"issue":"1","key":"10.1016\/j.cyto.2026.157107_bb0120","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1086\/315214","article-title":"Pro- versus anti-inflammatory cytokine profile in patients with severe Sepsis: a marker for prognosis and future therapeutic options","volume":"181","author":"Gogos","year":"2000","journal-title":"J. Infect. Dis."},{"issue":"9107","key":"10.1016\/j.cyto.2026.157107_bb0125","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/S0140-6736(05)60606-X","article-title":"Anti-inflammatory cytokine profile and mortality in febrile patients","volume":"351","author":"van Dissel","year":"1998","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.cyto.2026.157107_bb0130","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0154690","article-title":"Quantitative real-time polymerase chain reaction measurement of HLA-DRA gene expression in whole blood is highly reproducible and shows changes that reflect dynamic shifts in monocyte surface HLA-DR expression during the course of Sepsis","volume":"11","author":"Cajander","year":"2016","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.cyto.2026.157107_bb0135","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.4049\/jimmunol.166.2.1241","article-title":"Hepatocyte growth factor is a regulator of monocyte-macrophage function","volume":"166","author":"Galimi","year":"2001","journal-title":"J. Immunol."},{"issue":"12","key":"10.1016\/j.cyto.2026.157107_bb0140","doi-asserted-by":"crossref","first-page":"3964","DOI":"10.1182\/blood.V95.12.3964.012k20_3964_3969","article-title":"Hepatocyte growth factor-stimulated invasiveness of monocytes","volume":"95","author":"Beilmann","year":"2000","journal-title":"Blood"},{"issue":"3","key":"10.1016\/j.cyto.2026.157107_bb0145","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1177\/0885066621993423","article-title":"Prognostic significance of plasma hepatocyte growth factor in Sepsis","volume":"37","author":"Peng","year":"2022","journal-title":"J. Intensive Care Med."},{"issue":"47","key":"10.1016\/j.cyto.2026.157107_bb0150","doi-asserted-by":"crossref","first-page":"6816","DOI":"10.1038\/sj.onc.1210764","article-title":"Transcriptional control of granulocyte and monocyte development","volume":"26","author":"Friedman","year":"2007","journal-title":"Oncogene"},{"issue":"11","key":"10.1016\/j.cyto.2026.157107_bb0155","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1515\/hsz-2014-0195","article-title":"Epigenetic control of hematopoiesis: the PU.1 chromatin connection","volume":"395","author":"van Riel","year":"2014","journal-title":"Biol. Chem."},{"issue":"19","key":"10.1016\/j.cyto.2026.157107_bb0160","doi-asserted-by":"crossref","first-page":"5255","DOI":"10.1182\/blood-2011-03-341123","article-title":"Functional PU.1 in macrophages has a pivotal role in NF-kappaB activation and neutrophilic lung inflammation during endotoxemia","volume":"118","author":"Karpurapu","year":"2011","journal-title":"Blood"},{"issue":"3","key":"10.1016\/j.cyto.2026.157107_bb0165","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1097\/SHK.0000000000002072","article-title":"Screening of potential CORE genes in peripheral blood of adult patients with SEPSIS based on transcription regulation function","volume":"59","author":"Liu","year":"2023","journal-title":"Shock"},{"key":"10.1016\/j.cyto.2026.157107_bb0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2023.109909","article-title":"SPI1-mediated autophagy of peripheral blood monocyte cells as a mechanism for sepsis based on single-cell RNA sequencing","volume":"117","author":"Xie","year":"2023","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.cyto.2026.157107_bb0175","doi-asserted-by":"crossref","first-page":"401","DOI":"10.3389\/fimmu.2017.00401","volume":"8","author":"Lapko","year":"2017","journal-title":"Front. Immunol."},{"issue":"15","key":"10.1016\/j.cyto.2026.157107_bb0180","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1001\/archinte.167.15.1655","article-title":"Understanding the inflammatory cytokine response in pneumonia and sepsis: results of the genetic and inflammatory markers of Sepsis (GenIMS) study","volume":"167","author":"Kellum","year":"2007","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.cyto.2026.157107_bb0185","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/165974","article-title":"Cytokines in sepsis: potent immunoregulators and potential therapeutic targets--an updated view","volume":"2013","author":"Schulte","year":"2013","journal-title":"Mediat. Inflamm."},{"issue":"1","key":"10.1016\/j.cyto.2026.157107_bb0190","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1086\/315214","article-title":"Pro- versus anti-inflammatory cytokine profile in patients with severe sepsis: a marker for prognosis and future therapeutic options","volume":"181","author":"Gogos","year":"2000","journal-title":"J. Infect. Dis."},{"issue":"6","key":"10.1016\/j.cyto.2026.157107_bb0195","first-page":"669","article-title":"Role of cytokines as a double-edged sword in sepsis","volume":"27","author":"Chaudhry","year":"2013","journal-title":"In Vivo"},{"issue":"2","key":"10.1016\/j.cyto.2026.157107_bb0200","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1600-0463.2010.02705.x","article-title":"Multiplex cytokine profiling in patients with sepsis","volume":"119","author":"Mera","year":"2011","journal-title":"APMIS"},{"key":"10.1016\/j.cyto.2026.157107_bb0205","doi-asserted-by":"crossref","first-page":"1217784","DOI":"10.3389\/fmed.2023.1217784","article-title":"Monocyte chemoattractant protein-1 as a potential marker for patients with sepsis: a systematic review and meta-analysis","volume":"10","author":"Chen","year":"2023","journal-title":"Front. Med. (Lausanne)"},{"issue":"6","key":"10.1016\/j.cyto.2026.157107_bb0210","article-title":"Infection with SARS-CoV-2 is associated with elevated levels of IP-10, MCP-1, and IL-13 in Sepsis patients","volume":"13","author":"Eichhorn","year":"2023","journal-title":"Diagnostics (Basel)"},{"issue":"2","key":"10.1016\/j.cyto.2026.157107_bb0215","doi-asserted-by":"crossref","first-page":"R49","DOI":"10.1186\/cc5783","article-title":"Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis","volume":"11","author":"Bozza","year":"2007","journal-title":"Crit. Care"},{"issue":"7444","key":"10.1016\/j.cyto.2026.157107_bb0220","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1038\/nature11986","article-title":"Succinate is an inflammatory signal that induces IL-1\u03b2 through HIF-1\u03b1","volume":"496","author":"G\u00e1","year":"2013","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.cyto.2026.157107_bb0225","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1097\/SHK.0000000000002479","article-title":"Whole transcription analysis identified the regulation of hypoxia-inducible factors in monocytes with immune SUPPRESSION: implications for clinical outcomes","volume":"63","author":"Zhao","year":"2025","journal-title":"Shock"},{"issue":"5","key":"10.1016\/j.cyto.2026.157107_bb0230","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1084\/jem.20131916","article-title":"PD-L1 is a novel direct target of HIF-1\u03b1, and its blockade under hypoxia enhanced MDSC-mediated T cell activation","volume":"211","author":"Noman","year":"2014","journal-title":"J. Exp. Med."},{"issue":"4","key":"10.1016\/j.cyto.2026.157107_bb0235","doi-asserted-by":"crossref","first-page":"R120","DOI":"10.1186\/cc11414","article-title":"Hypoxia-inducible factor (HIF1alpha) gene expression in human shock states","volume":"16","author":"Textoris","year":"2012","journal-title":"Crit. Care"},{"issue":"4","key":"10.1016\/j.cyto.2026.157107_bb0240","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S2213-2600(16)00046-1","article-title":"Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study","volume":"4","author":"Davenport","year":"2016","journal-title":"Lancet Respir. Med."},{"issue":"7","key":"10.1016\/j.cyto.2026.157107_bb0245","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1164\/rccm.200612-1819OC","article-title":"The use of gene-expression profiling to identify candidate genes in human sepsis","volume":"176","author":"Tang","year":"2007","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"11","key":"10.1016\/j.cyto.2026.157107_bb0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2022.105301","article-title":"Single-cell transcriptome profiling reveals heterogeneous neutrophils with prognostic values in sepsis","volume":"25","author":"Hong","year":"2022","journal-title":"iScience"},{"issue":"1","key":"10.1016\/j.cyto.2026.157107_bb0255","doi-asserted-by":"crossref","first-page":"14917","DOI":"10.1038\/s41598-023-42081-6","article-title":"Predicting sepsis using a combination of clinical information and molecular immune markers sampled in the ambulance","volume":"13","author":"Tuerxun","year":"2023","journal-title":"Sci. Rep."}],"container-title":["Cytokine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043466626000025?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043466626000025?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T11:40:58Z","timestamp":1770205258000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1043466626000025"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":51,"alternative-id":["S1043466626000025"],"URL":"https:\/\/doi.org\/10.1016\/j.cyto.2026.157107","relation":{},"ISSN":["1043-4666"],"issn-type":[{"value":"1043-4666","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inflammatory imbalance in ambulance patients is associated with sepsis and septic shock","name":"articletitle","label":"Article Title"},{"value":"Cytokine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cyto.2026.157107","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"157107"}}