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A."},{"issue":"13","key":"10.1016\/j.cytogfr.2018.10.004_bib0370","doi-asserted-by":"crossref","first-page":"7222","DOI":"10.1074\/jbc.273.13.7222","article-title":"Amino-terminal truncation of chemokines by CD26\/dipeptidyl-peptidase IV. Conversion of RANTES into a potent inhibitor of monocyte chemotaxis and HIV-1-infection","volume":"273","author":"Proost","year":"1998","journal-title":"J. Biol. Chem."},{"issue":"7","key":"10.1016\/j.cytogfr.2018.10.004_bib0375","doi-asserted-by":"crossref","first-page":"2170","DOI":"10.1002\/1521-4141(200107)31:7<2170::AID-IMMU2170>3.0.CO;2-D","article-title":"Diverging binding capacities of natural LD78beta isoforms of macrophage inflammatory protein-1alpha to the CC chemokine receptors 1, 3 and 5 affect their anti-HIV-1 activity and chemotactic potencies for neutrophils and eosinophils","volume":"31","author":"Struyf","year":"2001","journal-title":"Eur. J. 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Res."},{"issue":"6","key":"10.1016\/j.cytogfr.2018.10.004_bib0485","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1167\/iovs.05-1499","article-title":"Proteomics implicates peptidyl arginine deiminase 2 and optic nerve citrullination in glaucoma pathogenesis","volume":"47","author":"Bhattacharya","year":"2006","journal-title":"Invest Ophthalmol. Vis. Sci."},{"issue":"4","key":"10.1016\/j.cytogfr.2018.10.004_bib0490","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1002\/jnr.490360409","article-title":"Gelatinase B is present in the cerebrospinal fluid during experimental autoimmune encephalomyelitis and cleaves myelin basic protein","volume":"36","author":"Gijbels","year":"1993","journal-title":"J. Neurosci. 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Med."},{"issue":"6","key":"10.1016\/j.cytogfr.2018.10.004_bib0550","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/j.coph.2009.08.003","article-title":"The role of chemokines in intestinal inflammation and cancer","volume":"9","author":"Wang","year":"2009","journal-title":"Curr. Opin. Pharmacol."},{"issue":"7","key":"10.1016\/j.cytogfr.2018.10.004_bib0555","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1002\/eji.200324807","article-title":"CXCR1-binding chemokines in inflammatory bowel diseases: down-regulated IL-8\/CXCL8 production by leukocytes in Crohn\u2019s disease and selective GCP-2\/CXCL6 expression in inflamed intestinal tissue","volume":"34","author":"Gijsbers","year":"2004","journal-title":"Eur. J. 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