{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T07:34:08Z","timestamp":1793691248525,"version":"4.5.1"},"reference-count":175,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,14]],"date-time":"2024-04-14T00:00:00Z","timestamp":1713052800000},"content-version":"am","delay-in-days":379,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AR061484"],"award-info":[{"award-number":["R01AR061484"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AR062207"],"award-info":[{"award-number":["R01AR062207"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AR076900"],"award-info":[{"award-number":["R01AR076900"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AR078035"],"award-info":[{"award-number":["R01AR078035"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01NS070328"],"award-info":[{"award-number":["R01NS070328"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cytokine &amp; Growth Factor Reviews"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.cytogfr.2023.03.002","type":"journal-article","created":{"date-parts":[[2023,3,5]],"date-time":"2023-03-05T02:33:58Z","timestamp":1677983638000},"page":"54-66","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":148,"special_numbering":"C","title":["Pathogenic mechanisms of glucocorticoid-induced osteoporosis"],"prefix":"10.1016","volume":"70","author":[{"given":"Meng","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenyu","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiyun","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuan-ju","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib1","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.tem.2017.10.010","article-title":"Therapeutic mechanisms of glucocorticoids","volume":"29","author":"Vandewalle","year":"2018","journal-title":"Trends Endocrinol. Metab."},{"issue":"8","key":"10.1016\/j.cytogfr.2023.03.002_bib2","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1038\/s41574-020-0341-0","article-title":"Pathogenesis of glucocorticoid-induced osteoporosis and options for treatment","volume":"16","author":"Chotiyarnwong","year":"2020","journal-title":"Nat. Rev. Endocrinol."},{"issue":"4","key":"10.1016\/j.cytogfr.2023.03.002_bib3","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1001\/jama.1955.02950210007003","article-title":"Studies on metacortandralone and metacortandracin in rheumatoid arthritis; antirheumatic potency, metabolic effects, and hormonal properties","volume":"157","author":"Bunim","year":"1955","journal-title":"J. Am. Med Assoc."},{"issue":"4","key":"10.1016\/j.cytogfr.2023.03.002_bib4","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1038\/s41584-020-0370-z","article-title":"Views on glucocorticoid therapy in rheumatology: the age of convergence","volume":"16","author":"Buttgereit","year":"2020","journal-title":"Nat. Rev. Rheuma"},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib5","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s12020-018-1588-2","article-title":"Glucocorticoid-induced osteoporosis: an update","volume":"61","author":"Compston","year":"2018","journal-title":"Endocrine"},{"issue":"6","key":"10.1016\/j.cytogfr.2023.03.002_bib6","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1359\/jbmr.2000.15.6.993","article-title":"Use of oral corticosteroids and risk of fractures","volume":"15","author":"Van Staa","year":"2000","journal-title":"J. Bone Min. Res"},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib7","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1056\/NEJMcp1012926","article-title":"Clinical practice. Glucocorticoid-induced bone disease","volume":"365","author":"Weinstein","year":"2011","journal-title":"N. Engl. J. Med"},{"issue":"26","key":"10.1016\/j.cytogfr.2023.03.002_bib8","doi-asserted-by":"crossref","first-page":"2547","DOI":"10.1056\/NEJMcp1800214","article-title":"Glucocorticoid-induced osteoporosis","volume":"379","author":"Buckley","year":"2018","journal-title":"N. Engl. J. Med"},{"issue":"7","key":"10.1016\/j.cytogfr.2023.03.002_bib9","doi-asserted-by":"crossref","first-page":"3613","DOI":"10.1210\/en.2005-0717","article-title":"Glucocorticoid regulation of osteoclast differentiation and expression of receptor activator of nuclear factor-kappaB (NF-kappaB) ligand, osteoprotegerin, and receptor activator of NF-kappaB in mouse calvarial bones","volume":"147","author":"Swanson","year":"2006","journal-title":"Endocrinology"},{"issue":"10","key":"10.1016\/j.cytogfr.2023.03.002_bib10","doi-asserted-by":"crossref","first-page":"4382","DOI":"10.1210\/endo.140.10.7034","article-title":"Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis","volume":"140","author":"Hofbauer","year":"1999","journal-title":"Endocrinology"},{"issue":"3","key":"10.1016\/j.cytogfr.2023.03.002_bib11","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1210\/endo.139.3.5778","article-title":"Dexamethasone promotes expression of membrane-bound macrophage colony-stimulating factor in murine osteoblast-like cells","volume":"139","author":"Rubin","year":"1998","journal-title":"Endocrinology"},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib12","doi-asserted-by":"crossref","first-page":"9925","DOI":"10.1038\/s41598-017-09793-y","article-title":"Transforming growth factor beta is regulated by a glucocorticoid-dependent mechanism in denervation mouse bone","volume":"7","author":"Li","year":"2017","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib13","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1677\/joe.1.05962","article-title":"Dexamethasone suppresses Smad3 pathway in osteoblastic cells","volume":"185","author":"Iu","year":"2005","journal-title":"J. Endocrinol."},{"issue":"7","key":"10.1016\/j.cytogfr.2023.03.002_bib14","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1359\/jbmr.2003.18.7.1186","article-title":"Bone morphogenetic protein-2 restores mineralization in glucocorticoid-inhibited MC3T3-E1 osteoblast cultures","volume":"18","author":"Luppen","year":"2003","journal-title":"J. Bone Min. Res"},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib15","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.bbrc.2005.01.117","article-title":"Glucocorticoid suppresses the canonical Wnt signal in cultured human osteoblasts","volume":"329","author":"Ohnaka","year":"2005","journal-title":"Biochem Biophys. Res Commun."},{"issue":"7","key":"10.1016\/j.cytogfr.2023.03.002_bib16","doi-asserted-by":"crossref","DOI":"10.3390\/molecules25071489","article-title":"Glucocorticoids influencing Wnt\/beta-Catenin pathway; multiple sites, heterogeneous effects","volume":"25","author":"Meszaros","year":"2020","journal-title":"Molecules"},{"issue":"5","key":"10.1016\/j.cytogfr.2023.03.002_bib17","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1210\/er.2018-00097","article-title":"Glucocorticoids and bone: consequences of endogenous and exogenous excess and replacement therapy","volume":"39","author":"Hardy","year":"2018","journal-title":"Endocr. Rev."},{"issue":"3","key":"10.1016\/j.cytogfr.2023.03.002_bib18","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.jbo.2016.03.007","article-title":"The role of osteoblasts in bone metastasis","volume":"5","author":"Ottewell","year":"2016","journal-title":"J. Bone Oncol."},{"issue":"26","key":"10.1016\/j.cytogfr.2023.03.002_bib19","doi-asserted-by":"crossref","first-page":"19992","DOI":"10.1074\/jbc.M001758200","article-title":"Glucocorticoids inhibit developmental stage-specific osteoblast cell cycle. Dissociation of cyclin A-cyclin-dependent kinase 2 from E2F4-p130 complexes","volume":"275","author":"Smith","year":"2000","journal-title":"J. Biol. Chem."},{"issue":"6","key":"10.1016\/j.cytogfr.2023.03.002_bib20","article-title":"Glucocorticoid receptor and sequential P53 activation by dexamethasone mediates apoptosis and cell cycle arrest of osteoblastic MC3T3-E1 cells","volume":"7","author":"Li","year":"2012","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.cytogfr.2023.03.002_bib21","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1530\/JME-14-0314","article-title":"Glucocorticoid inhibits cell proliferation in differentiating osteoblasts by microRNA-199a targeting of WNT signaling","volume":"54","author":"Shi","year":"2015","journal-title":"J. Mol. Endocrinol."},{"issue":"4","key":"10.1016\/j.cytogfr.2023.03.002_bib22","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1002\/jcp.22412","article-title":"Developmentally regulated inhibition of cell cycle progression by glucocorticoids through repression of cyclin A transcription in primary osteoblast cultures","volume":"226","author":"Gabet","year":"2011","journal-title":"J. Cell Physiol."},{"issue":"11","key":"10.1016\/j.cytogfr.2023.03.002_bib23","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.2174\/1389201021666201216150442","article-title":"Luteolin stimulates proliferation and inhibits late differentiation of primary rat calvarial osteoblast induced by high-dose dexamethasone via Sema3A \/NRP1\/Pleixin A1","volume":"22","author":"Zheng","year":"2021","journal-title":"Curr. Pharm. Biotechnol."},{"key":"10.1016\/j.cytogfr.2023.03.002_bib24","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.tox.2009.01.016","article-title":"Anti-inflammatory drugs suppress proliferation and induce apoptosis through altering expressions of cell cycle regulators and pro-apoptotic factors in cultured human osteoblasts","author":"Chang","year":"2009","journal-title":"Toxicology 258(2-3)"},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib25","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/ncprheum0070","article-title":"Mechanisms of disease: is osteoporosis the obesity of bone?","volume":"2","author":"Rosen","year":"2006","journal-title":"Nat. Clin. Pr. Rheuma"},{"key":"10.1016\/j.cytogfr.2023.03.002_bib26","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2013.348","article-title":"Dexamethasone shifts bone marrow stromal cells from osteoblasts to adipocytes by C\/EBPalpha promoter methylation","volume":"4","author":"Li","year":"2013","journal-title":"Cell Death Dis."},{"issue":"3","key":"10.1016\/j.cytogfr.2023.03.002_bib27","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1002\/jcp.22392","article-title":"Dexamethasone modulates osteogenesis and adipogenesis with regulation of osterix expression in rat calvaria-derived cells","volume":"226","author":"Mikami","year":"2011","journal-title":"J. Cell Physiol."},{"issue":"6","key":"10.1016\/j.cytogfr.2023.03.002_bib28","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1007\/s00418-012-1007-3","article-title":"Inhibition of Wnt\/beta-catenin signaling by dexamethasone promotes adipocyte differentiation in mesenchymal progenitor cells, ROB-C26","volume":"138","author":"Naito","year":"2012","journal-title":"Histochem Cell Biol."},{"issue":"5","key":"10.1016\/j.cytogfr.2023.03.002_bib29","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/S8756-3282(02)00687-7","article-title":"Effects of cortisol and bone morphogenetic protein-2 on stromal cell differentiation: correlation with CCAAT-enhancer binding protein expression","volume":"30","author":"Pereira","year":"2002","journal-title":"Bone"},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib30","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1677\/jme.0.0330175","article-title":"Gene expression profiling of glucocorticoid-inhibited osteoblasts","volume":"33","author":"Leclerc","year":"2004","journal-title":"J. Mol. Endocrinol."},{"issue":"6","key":"10.1016\/j.cytogfr.2023.03.002_bib31","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1002\/art.23454","article-title":"Glucocorticoid excess in mice results in early activation of osteoclastogenesis and adipogenesis and prolonged suppression of osteogenesis: a longitudinal study of gene expression in bone tissue from glucocorticoid-treated mice","volume":"58","author":"Yao","year":"2008","journal-title":"Arthritis Rheum."},{"issue":"4","key":"10.1016\/j.cytogfr.2023.03.002_bib32","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s11102-005-1051-2","article-title":"Cushing's syndrome and bone","volume":"7","author":"Mancini","year":"2004","journal-title":"Pituitary"},{"issue":"7","key":"10.1016\/j.cytogfr.2023.03.002_bib33","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1002\/1529-0131(199907)42:7<1405::AID-ANR14>3.0.CO;2-W","article-title":"Fat conversion of femoral marrow in glucocorticoid-treated patients: a cross-sectional and longitudinal study with magnetic resonance imaging","volume":"42","author":"Vande Berg","year":"1999","journal-title":"Arthritis Rheum."},{"issue":"3","key":"10.1016\/j.cytogfr.2023.03.002_bib34","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1177\/1535370213519215","article-title":"Pravastatin prevents steroid-induced osteonecrosis in rats by suppressing PPARgamma expression and activating Wnt signaling pathway","volume":"239","author":"Jiang","year":"2014","journal-title":"Exp. Biol. Med."},{"issue":"7","key":"10.1016\/j.cytogfr.2023.03.002_bib35","doi-asserted-by":"crossref","first-page":"2947","DOI":"10.1007\/s10067-020-05554-x","article-title":"Glucocorticoid therapy suppresses Wnt signaling by reducing the ratio of serum Wnt3a to Wnt inhibitors, sFRP-1 and Wif-1","volume":"40","author":"Kawazoe","year":"2021","journal-title":"Clin. Rheuma"},{"issue":"6","key":"10.1016\/j.cytogfr.2023.03.002_bib36","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1007\/s00223-009-9303-1","article-title":"Biphasic glucocorticoid-dependent regulation of Wnt expression and its inhibitors in mature osteoblastic cells","volume":"85","author":"Mak","year":"2009","journal-title":"Calcif. Tissue Int"},{"issue":"4","key":"10.1016\/j.cytogfr.2023.03.002_bib37","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1002\/jbmr.3947","article-title":"Involvement of the gut microbiota and barrier function in glucocorticoid-induced osteoporosis","volume":"35","author":"Schepper","year":"2020","journal-title":"J. Bone Min. Res"},{"key":"10.1016\/j.cytogfr.2023.03.002_bib38","doi-asserted-by":"crossref","first-page":"558","DOI":"10.3389\/fphar.2017.00558","article-title":"Adenosine receptor stimulation improves glucocorticoid-induced osteoporosis in a rat model","volume":"8","author":"Pizzino","year":"2017","journal-title":"Front Pharm."},{"issue":"2","key":"10.1016\/j.cytogfr.2023.03.002_bib39","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/nm.3074","article-title":"WNT signaling in bone homeostasis and disease: from human mutations to treatments","volume":"19","author":"Baron","year":"2013","journal-title":"Nat. Med"},{"issue":"9","key":"10.1016\/j.cytogfr.2023.03.002_bib40","doi-asserted-by":"crossref","first-page":"3324","DOI":"10.1073\/pnas.0408742102","article-title":"Regulation of osteoblastogenesis and bone mass by Wnt10b","volume":"102","author":"Bennett","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.cytogfr.2023.03.002_bib41","doi-asserted-by":"crossref","first-page":"4493","DOI":"10.1038\/srep04493","article-title":"Noncanonical Wnt5a enhances Wnt\/beta-catenin signaling during osteoblastogenesis","volume":"4","author":"Okamoto","year":"2014","journal-title":"Sci. Rep."},{"issue":"7","key":"10.1016\/j.cytogfr.2023.03.002_bib42","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1002745","article-title":"WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk","volume":"8","author":"Zheng","year":"2012","journal-title":"PLoS Genet"},{"issue":"2","key":"10.1016\/j.cytogfr.2023.03.002_bib43","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1210\/en.2015-1281","article-title":"Osteoblast-specific overexpression of human WNT16 increases both cortical and trabecular bone mass and structure in mice","volume":"157","author":"Alam","year":"2016","journal-title":"Endocrinology"},{"issue":"11","key":"10.1016\/j.cytogfr.2023.03.002_bib44","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1038\/nm.3654","article-title":"Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures","volume":"20","author":"Moverare-Skrtic","year":"2014","journal-title":"Nat. Med"},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib45","doi-asserted-by":"crossref","first-page":"8711","DOI":"10.1038\/s41598-018-26300-z","article-title":"Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo","volume":"8","author":"Hildebrandt","year":"2018","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib46","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.bbrc.2004.04.025","article-title":"Glucocorticoid enhances the expression of dickkopf-1 in human osteoblasts: novel mechanism of glucocorticoid-induced osteoporosis","volume":"318","author":"Ohnaka","year":"2004","journal-title":"Biochem Biophys. Res Commun."},{"issue":"5","key":"10.1016\/j.cytogfr.2023.03.002_bib47","doi-asserted-by":"crossref","first-page":"2415","DOI":"10.1210\/en.2004-1050","article-title":"Secreted frizzled-related protein 1 modulates glucocorticoid attenuation of osteogenic activities and bone mass","volume":"146","author":"Wang","year":"2005","journal-title":"Endocrinology"},{"issue":"3","key":"10.1016\/j.cytogfr.2023.03.002_bib48","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1007\/s00441-013-1696-5","article-title":"Up-regulation of Axin2 by dexamethasone promotes adipocyte differentiation in ROB-C26 mesenchymal progenitor cells","volume":"354","author":"Naito","year":"2013","journal-title":"Cell Tissue Res"},{"issue":"20","key":"10.1016\/j.cytogfr.2023.03.002_bib49","doi-asserted-by":"crossref","first-page":"18191","DOI":"10.1074\/jbc.M109708200","article-title":"Glucocorticoids inhibit cell cycle progression in differentiating osteoblasts via glycogen synthase kinase-3beta","volume":"277","author":"Smith","year":"2002","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.cytogfr.2023.03.002_bib50","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.bone.2013.09.019","article-title":"MicroRNA-29a ameliorates glucocorticoid-induced suppression of osteoblast differentiation by regulating beta-catenin acetylation","volume":"57","author":"Ko","year":"2013","journal-title":"Bone"},{"issue":"22","key":"10.1016\/j.cytogfr.2023.03.002_bib51","doi-asserted-by":"crossref","first-page":"3801","DOI":"10.1242\/dev.025825","article-title":"BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway","volume":"135","author":"Kamiya","year":"2008","journal-title":"Development"},{"issue":"45","key":"10.1016\/j.cytogfr.2023.03.002_bib52","doi-asserted-by":"crossref","first-page":"44995","DOI":"10.1074\/jbc.M306730200","article-title":"Brief bone morphogenetic protein 2 treatment of glucocorticoid-inhibited MC3T3-E1 osteoblasts rescues commitment-associated cell cycle and mineralization without alteration of Runx2","volume":"278","author":"Luppen","year":"2003","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.cytogfr.2023.03.002_bib53","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.bbrc.2008.12.035","article-title":"BMP\/Wnt antagonists are upregulated by dexamethasone in osteoblasts and reversed by alendronate and PTH: potential therapeutic targets for glucocorticoid-induced osteoporosis","volume":"379","author":"Hayashi","year":"2009","journal-title":"Biochem Biophys. Res Commun."},{"key":"10.1016\/j.cytogfr.2023.03.002_bib54","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.freeradbiomed.2022.08.007","article-title":"A novel BMP2 secretagogue ameliorates glucocorticoid induced oxidative stress in osteoblasts by activating NRF2 dependent survival while promoting Wnt\/beta-catenin mediated osteogenesis","volume":"190","author":"Rai","year":"2022","journal-title":"Free Radic. Biol. Med"},{"issue":"7","key":"10.1016\/j.cytogfr.2023.03.002_bib55","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20071694","article-title":"Regulation of proliferation, differentiation and functions of osteoblasts by Runx2","volume":"20","author":"Komori","year":"2019","journal-title":"Int J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib56","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1002\/jcb.24646","article-title":"Glucocorticoids antagonize RUNX2 during osteoblast differentiation in cultures of ST2 pluripotent mesenchymal cells","volume":"115","author":"Koromila","year":"2014","journal-title":"J. Cell Biochem"},{"issue":"6","key":"10.1016\/j.cytogfr.2023.03.002_bib57","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.cmet.2010.05.005","article-title":"Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor","volume":"11","author":"Rauch","year":"2010","journal-title":"Cell Metab."},{"issue":"12","key":"10.1016\/j.cytogfr.2023.03.002_bib58","doi-asserted-by":"crossref","DOI":"10.3390\/cells10123424","article-title":"Geniposide ameliorated dexamethasone-induced cholesterol accumulation in osteoblasts by mediating the GLP-1R\/ABCA1 Axis","volume":"10","author":"Zheng","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.cytogfr.2023.03.002_bib59","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2020.601224","article-title":"Recent advances of osterix transcription factor in osteoblast differentiation and bone formation","volume":"8","author":"Liu","year":"2020","journal-title":"Front Cell Dev. Biol."},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib60","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1002\/jcp.22017","article-title":"Bone morphogenetic protein 2 and dexamethasone synergistically increase alkaline phosphatase levels through JAK\/STAT signaling in C3H10T1\/2 cells","volume":"223","author":"Mikami","year":"2010","journal-title":"J. Cell Physiol."},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib61","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1186\/s13075-019-1972-1","article-title":"11beta-HSD1 plays a critical role in trabecular bone loss associated with systemic glucocorticoid therapy","volume":"21","author":"Fenton","year":"2019","journal-title":"Arthritis Res Ther."},{"issue":"2","key":"10.1016\/j.cytogfr.2023.03.002_bib62","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines10020404","article-title":"Inhibition of Cdk5 ameliorates skeletal bone loss in glucocorticoid-treated mice","volume":"10","author":"Kruger","year":"2022","journal-title":"Biomedicines"},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib63","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1080\/10799893.2019.1625061","article-title":"Dexamethasone suppresses osteogenesis of osteoblast via the PI3K\/Akt signaling pathway in vitro and in vivo","volume":"39","author":"Pan","year":"2019","journal-title":"J. Recept Signal Transduct. Res"},{"key":"10.1016\/j.cytogfr.2023.03.002_bib64","doi-asserted-by":"crossref","first-page":"922","DOI":"10.3389\/fendo.2019.00922","article-title":"HIF-1alpha regulates glucocorticoid-induced osteoporosis through PDK1\/AKT\/mTOR Signaling pathway","volume":"10","author":"Xu","year":"2019","journal-title":"Front Endocrinol."},{"issue":"4","key":"10.1016\/j.cytogfr.2023.03.002_bib65","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1530\/JME-21-0213","article-title":"Glucocorticoids inhibit the maturation of committed osteoblasts via SOX2","volume":"68","author":"Chen","year":"2022","journal-title":"J. Mol. Endocrinol."},{"issue":"8","key":"10.1016\/j.cytogfr.2023.03.002_bib66","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1038\/cdd.2010.57","article-title":"The transcription factor Sox2 is required for osteoblast self-renewal","volume":"17","author":"Basu-Roy","year":"2010","journal-title":"Cell Death Differ."},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib67","doi-asserted-by":"crossref","DOI":"10.1016\/j.yexcr.2021.112595","article-title":"Glucocorticoids suppressed osteoblast differentiation by decreasing Sema3A expression via the PIK3\/Akt pathway","volume":"403","author":"Xing","year":"2021","journal-title":"Exp. Cell Res"},{"issue":"6","key":"10.1016\/j.cytogfr.2023.03.002_bib68","doi-asserted-by":"crossref","DOI":"10.1038\/nrd3759","article-title":"SEMA3A strikes a balance in bone homeostasis","volume":"11","author":"Tse","year":"2012","journal-title":"Nat. Rev. Drug Discov."},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib69","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/s10020-022-00453-0","article-title":"Activation of dopamine receptor D1 promotes osteogenic differentiation and reduces glucocorticoid-induced bone loss by upregulating the ERK1\/2 signaling pathway","volume":"28","author":"Zhu","year":"2022","journal-title":"Mol. Med"},{"issue":"12","key":"10.1016\/j.cytogfr.2023.03.002_bib70","doi-asserted-by":"crossref","first-page":"9191","DOI":"10.1002\/jcp.26939","article-title":"Therapeutic potential of microRNAs in osteoporosis function by regulating the biology of cells related to bone homeostasis","volume":"233","author":"Zhao","year":"2018","journal-title":"J. Cell Physiol."},{"issue":"10","key":"10.1016\/j.cytogfr.2023.03.002_bib71","doi-asserted-by":"crossref","first-page":"2182","DOI":"10.7150\/ijbs.33490","article-title":"Let-7f-5p regulates TGFBR1 in glucocorticoid-inhibited osteoblast differentiation and ameliorates glucocorticoid-induced bone loss","volume":"15","author":"Shen","year":"2019","journal-title":"Int. J. Biol. Sci."},{"issue":"12","key":"10.1016\/j.cytogfr.2023.03.002_bib72","doi-asserted-by":"crossref","first-page":"2532","DOI":"10.1002\/cbin.11460","article-title":"microRNA-199a counteracts glucocorticoid inhibition of bone marrow mesenchymal stem cell osteogenic differentiation through regulation of Klotho expression in vitro","volume":"44","author":"Tang","year":"2020","journal-title":"Cell Biol. Int"},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib73","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1186\/s13287-021-02278-w","article-title":"miR-133a silencing rescues glucocorticoid-induced bone loss by regulating the MAPK\/ERK signaling pathway","volume":"12","author":"Wang","year":"2021","journal-title":"Stem Cell Res Ther."},{"issue":"18","key":"10.1016\/j.cytogfr.2023.03.002_bib74","doi-asserted-by":"crossref","first-page":"3259","DOI":"10.1002\/1878-0261.13269","article-title":"Autophagy at the intersection of aging, senescence, and cancer","volume":"16","author":"Cassidy","year":"2022","journal-title":"Mol. Oncol."},{"issue":"3","key":"10.1016\/j.cytogfr.2023.03.002_bib75","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1080\/15548627.2021.1936359","article-title":"Targeting autophagy in disease: established and new strategies","volume":"18","author":"Kocak","year":"2022","journal-title":"Autophagy"},{"issue":"10","key":"10.1016\/j.cytogfr.2023.03.002_bib76","doi-asserted-by":"crossref","DOI":"10.3390\/cancers11101465","article-title":"Autophagy function and dysfunction: potential drugs as anti-cancer therapy","volume":"11","author":"Cuomo","year":"2019","journal-title":"Cancers"},{"issue":"6","key":"10.1016\/j.cytogfr.2023.03.002_bib77","doi-asserted-by":"crossref","first-page":"4152","DOI":"10.1002\/jcp.30111","article-title":"The role of autophagy in bone homeostasis","volume":"236","author":"Guo","year":"2021","journal-title":"J. Cell Physiol."},{"issue":"15","key":"10.1016\/j.cytogfr.2023.03.002_bib78","doi-asserted-by":"crossref","first-page":"2683","DOI":"10.1007\/s00018-018-2776-1","article-title":"Autophagy as a target for glucocorticoid-induced osteoporosis therapy","volume":"75","author":"Shen","year":"2018","journal-title":"Cell Mol. Life Sci."},{"issue":"14","key":"10.1016\/j.cytogfr.2023.03.002_bib79","doi-asserted-by":"crossref","first-page":"2675","DOI":"10.7150\/ijbs.46627","article-title":"The Role of Autophagy and Mitophagy in Bone Metabolic Disorders","volume":"16","author":"Wang","year":"2020","journal-title":"Int J. Biol. Sci."},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib80","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s00198-015-3308-6","article-title":"Sclerostin-antibody treatment of glucocorticoid-induced osteoporosis maintained bone mass and strength","volume":"27","author":"Yao","year":"2016","journal-title":"Osteoporos. Int"},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib81","first-page":"158","article-title":"Effect of betaecdysterone on glucocorticoidinduced apoptosis and autophagy in osteoblasts","volume":"17","author":"Tang","year":"2018","journal-title":"Mol. Med Rep."},{"key":"10.1016\/j.cytogfr.2023.03.002_bib82","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.3389\/fphar.2020.01209","article-title":"Vitamin K2 can rescue the dexamethasone-induced downregulation of osteoblast autophagy and mitophagy thereby restoring osteoblast function in vitro and in vivo","volume":"11","author":"Chen","year":"2020","journal-title":"Front Pharm."},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib83","doi-asserted-by":"crossref","first-page":"18424","DOI":"10.1038\/s41598-019-44766-3","article-title":"The role and mechanism of SIRT1 in resveratrol-regulated osteoblast autophagy in osteoporosis rats","volume":"9","author":"Yang","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.cytogfr.2023.03.002_bib84","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.113829","article-title":"Geniposide ameliorates glucocorticoid-induced osteoblast apoptosis by activating autophagy","volume":"155","author":"Huang","year":"2022","journal-title":"Biomed. Pharm."},{"issue":"10","key":"10.1016\/j.cytogfr.2023.03.002_bib85","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1080\/15548627.2021.2017587","article-title":"Degradation of the NOTCH intracellular domain by elevated autophagy in osteoblasts promotes osteoblast differentiation and alleviates osteoporosis","volume":"18","author":"Yoshida","year":"2022","journal-title":"Autophagy"},{"key":"10.1016\/j.cytogfr.2023.03.002_bib86","doi-asserted-by":"crossref","unstructured":"J. Zhu, T. Zhao, L. Zhu, C. Yin, Y. Liu, J. Fang, H. Liang, Y. Zhen, Dexamethasone promotes osteoblast apoptosis through the Chk2\/p53 signaling pathway, Adv Clin Exp Med (2022).","DOI":"10.17219\/acem\/152150"},{"issue":"7","key":"10.1016\/j.cytogfr.2023.03.002_bib87","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1007\/s00198-010-1434-8","article-title":"Quantitative proteomic analysis of dexamethasone-induced effects on osteoblast differentiation, proliferation, and apoptosis in MC3T3-E1 cells using SILAC","volume":"22","author":"Hong","year":"2011","journal-title":"Osteoporos. Int"},{"key":"10.1016\/j.cytogfr.2023.03.002_bib88","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.biopha.2018.11.103","article-title":"Dexamethasone induces osteoblast apoptosis through ROS-PI3K\/AKT\/GSK3beta signaling pathway","volume":"110","author":"Deng","year":"2019","journal-title":"Biomed. Pharm."},{"issue":"2","key":"10.1016\/j.cytogfr.2023.03.002_bib89","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1002\/jcp.21335","article-title":"Regulation of bim in glucocorticoid-mediated osteoblast apoptosis","volume":"215","author":"Espina","year":"2008","journal-title":"J. Cell Physiol."},{"issue":"3","key":"10.1016\/j.cytogfr.2023.03.002_bib90","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1359\/JBMR.0301242","article-title":"Prevention of glucocorticoid-induced apoptosis in osteocytes and osteoblasts by calbindin-D28k","volume":"19","author":"Liu","year":"2004","journal-title":"J. Bone Min. Res"},{"issue":"12","key":"10.1016\/j.cytogfr.2023.03.002_bib91","doi-asserted-by":"crossref","first-page":"7841","DOI":"10.1007\/s11033-021-06806-y","article-title":"High doses of dexamethasone induce endoplasmic reticulum stress-mediated apoptosis by promoting calcium ion influx-dependent CHOP expression in osteoblasts","volume":"48","author":"Guo","year":"2021","journal-title":"Mol. Biol. Rep."},{"issue":"52","key":"10.1016\/j.cytogfr.2023.03.002_bib92","doi-asserted-by":"crossref","first-page":"44326","DOI":"10.1074\/jbc.M111.283481","article-title":"Glucocorticoids and tumor necrosis factor alpha increase oxidative stress and suppress Wnt protein signaling in osteoblasts","volume":"286","author":"Almeida","year":"2011","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.cytogfr.2023.03.002_bib93","doi-asserted-by":"crossref","first-page":"70","DOI":"10.4103\/CJP.CJP_7_19","article-title":"Different susceptibilities of osteoclasts and osteoblasts to glucocorticoid-induced oxidative stress and mitochondrial alterations","volume":"62","author":"Chen","year":"2019","journal-title":"Chin. J. Physiol."},{"key":"10.1016\/j.cytogfr.2023.03.002_bib94","first-page":"29","article-title":"Haem oxygenase-1 induction prevents glucocorticoid-induced osteoblast apoptosis through activation of extracellular signal-regulated kinase1\/2 signalling pathway","volume":"19","author":"Gu","year":"2019","journal-title":"J. Orthop. Transl."},{"key":"10.1016\/j.cytogfr.2023.03.002_bib95","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.bcp.2016.12.009","article-title":"Heme oxygenase (HO)-1 induction prevents Endoplasmic Reticulum stress-mediated endothelial cell death and impaired angiogenic capacity","volume":"127","author":"Maamoun","year":"2017","journal-title":"Biochem Pharm."},{"key":"10.1016\/j.cytogfr.2023.03.002_bib96","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.intimp.2018.05.007","article-title":"The effect of natural antioxidants in cyclophosphamide-induced hepatotoxicity: role of Nrf2\/HO-1 pathway","volume":"61","author":"Sherif","year":"2018","journal-title":"Int Immunopharmacol."},{"key":"10.1016\/j.cytogfr.2023.03.002_bib97","doi-asserted-by":"crossref","first-page":"411","DOI":"10.3389\/fphar.2019.00411","article-title":"Geniposide alleviates glucocorticoid-induced inhibition of osteogenic differentiation in MC3T3-E1 cells by ERK pathway","volume":"10","author":"Xie","year":"2019","journal-title":"Front Pharm."},{"key":"10.1016\/j.cytogfr.2023.03.002_bib98","first-page":"6623464","article-title":"Paeoniflorin attenuates dexamethasone-induced apoptosis of osteoblast cells and promotes bone formation via regulating AKT\/mTOR\/autophagy signaling pathway","volume":"2021","author":"Yang","year":"2021","journal-title":"Evid. Based Complement Altern. Med"},{"issue":"4","key":"10.1016\/j.cytogfr.2023.03.002_bib99","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1002\/jcb.240500411","article-title":"Glucocorticoids promote development of the osteoblast phenotype by selectively modulating expression of cell growth and differentiation associated genes","volume":"50","author":"Shalhoub","year":"1992","journal-title":"J. Cell Biochem"},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib100","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1210\/endo.134.1.8275945","article-title":"Differentiation of human bone marrow osteogenic stromal cells in vitro: induction of the osteoblast phenotype by dexamethasone","volume":"134","author":"Cheng","year":"1994","journal-title":"Endocrinology"},{"issue":"2","key":"10.1016\/j.cytogfr.2023.03.002_bib101","first-page":"800","article-title":"Autophagy relieves the function inhibition and apoptosis\u2011promoting effects on osteoblast induced by glucocorticoid","volume":"41","author":"Han","year":"2018","journal-title":"Int J. Mol. Med"},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib102","doi-asserted-by":"crossref","first-page":"66","DOI":"10.3109\/07420528.2011.636496","article-title":"Comparison of \u03b2-adrenergic and glucocorticoid signaling on clock gene and osteoblast-related gene expressions in human osteoblast","volume":"29","author":"Komoto","year":"2012","journal-title":"Chronobiol. Int."},{"issue":"3","key":"10.1016\/j.cytogfr.2023.03.002_bib103","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1002\/jcb.240570314","article-title":"Cortisol downregulates osteoblast alpha 1 (I) procollagen mRNA by transcriptional and posttranscriptional mechanisms","volume":"57","author":"Delany","year":"1995","journal-title":"J. Cell Biochem"},{"issue":"44","key":"10.1016\/j.cytogfr.2023.03.002_bib104","doi-asserted-by":"crossref","first-page":"26607","DOI":"10.1074\/jbc.270.44.26607","article-title":"Cortisol increases interstitial collagenase expression in osteoblasts by post-transcriptional mechanisms","volume":"270","author":"Delany","year":"1995","journal-title":"J. Biol. Chem."},{"issue":"6937","key":"10.1016\/j.cytogfr.2023.03.002_bib105","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/nature01658","article-title":"Osteoclast differentiation and activation","volume":"423","author":"Boyle","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.cytogfr.2023.03.002_bib106","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.abb.2014.06.017","article-title":"The great beauty of the osteoclast","volume":"558","author":"Cappariello","year":"2014","journal-title":"Arch. Biochem Biophys."},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib107","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s11914-009-0005-4","article-title":"Glucocorticoid-induced osteoporosis","volume":"7","author":"Silverman","year":"2009","journal-title":"Curr. Osteoporos. Rep."},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib108","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1023\/A:1010007108155","article-title":"Glucocorticoid-induced osteoporosis","volume":"2","author":"Weinstein","year":"2001","journal-title":"Rev. Endocr. Metab. Disord."},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib109","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.molmed.2005.11.007","article-title":"RANKL-RANK signaling in osteoclastogenesis and bone disease","volume":"12","author":"Wada","year":"2006","journal-title":"Trends Mol. Med"},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib110","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s00774-020-01162-6","article-title":"Osteoclast differentiation by RANKL and OPG signaling pathways","volume":"39","author":"Udagawa","year":"2021","journal-title":"J. Bone Min. Metab."},{"issue":"2","key":"10.1016\/j.cytogfr.2023.03.002_bib111","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1152\/physrev.00011.2015","article-title":"Molecular actions of glucocorticoids in cartilage and bone during health, disease, and steroid therapy","volume":"96","author":"Hartmann","year":"2016","journal-title":"Physiol. Rev."},{"issue":"8","key":"10.1016\/j.cytogfr.2023.03.002_bib112","doi-asserted-by":"crossref","first-page":"2797","DOI":"10.1210\/en.2014-1046","article-title":"Parathyroid hormone receptor signaling induces bone resorption in the adult skeleton by directly regulating the RANKL gene in osteocytes","volume":"155","author":"Ben-awadh","year":"2014","journal-title":"Endocrinology"},{"key":"10.1016\/j.cytogfr.2023.03.002_bib113","first-page":"1","article-title":"Parathyroid hormone-dependent signaling pathways regulating genes in bone cells","author":"Swarthout","year":"2002","journal-title":"Gene 282(1-2)"},{"issue":"12","key":"10.1016\/j.cytogfr.2023.03.002_bib114","doi-asserted-by":"crossref","first-page":"14394","DOI":"10.1096\/fj.201802729RRR","article-title":"Glucocorticoids employ the monomeric glucocorticoid receptor to potentiate vitamin D3 and parathyroid hormone-induced osteoclastogenesis","volume":"33","author":"Conaway","year":"2019","journal-title":"FASEB J."},{"issue":"4","key":"10.1016\/j.cytogfr.2023.03.002_bib115","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/j.bbrc.2009.03.111","article-title":"Bone marrow adipocytes support dexamethasone-induced osteoclast differentiation","volume":"382","author":"Hozumi","year":"2009","journal-title":"Biochem Biophys. Res Commun."},{"issue":"12","key":"10.1016\/j.cytogfr.2023.03.002_bib116","doi-asserted-by":"crossref","first-page":"4592","DOI":"10.1172\/JCI60920","article-title":"Inflammatory arthritis increases mouse osteoclast precursors with myeloid suppressor function","volume":"122","author":"Charles","year":"2012","journal-title":"J. Clin. Invest"},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib117","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.yexcr.2016.11.018","article-title":"Integrin alphaMbeta2 is differently expressed by subsets of human osteoclast precursors and mediates adhesion of classical monocytes to bone","volume":"350","author":"Sprangers","year":"2017","journal-title":"Exp. Cell Res"},{"key":"10.1016\/j.cytogfr.2023.03.002_bib118","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.intimp.2018.10.016","article-title":"Monocytes in rheumatoid arthritis: circulating precursors of macrophages and osteoclasts and, their heterogeneity and plasticity role in RA pathogenesis","volume":"65","author":"Rana","year":"2018","journal-title":"Int Immunopharmacol."},{"key":"10.1016\/j.cytogfr.2023.03.002_bib119","doi-asserted-by":"crossref","unstructured":"P. Liu, Y. Gao, P. Luo, H. Yu, S. Guo, F. Liu, J. Gao, J. Xu, S. Wang, C. Zhang, Glucocorticoid-induced expansion of classical monocytes contributes to bone loss, Exp Mol Med (2022).","DOI":"10.1038\/s12276-022-00764-6"},{"issue":"20","key":"10.1016\/j.cytogfr.2023.03.002_bib120","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20205141","article-title":"MicroRNA-29a counteracts glucocorticoid induction of bone loss through repressing TNFSF13b modulation of osteoclastogenesis","volume":"20","author":"Wu","year":"2019","journal-title":"Int J. Mol. Sci."},{"issue":"7","key":"10.1016\/j.cytogfr.2023.03.002_bib121","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1002\/jbmr.5650090718","article-title":"High-dose glucocorticoids in multiple sclerosis patients exert direct effects on the kidney and skeleton","volume":"9","author":"Cosman","year":"1994","journal-title":"J. Bone Min. Res"},{"issue":"7","key":"10.1016\/j.cytogfr.2023.03.002_bib122","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1093\/clinchem\/47.7.1314","article-title":"Biomarkers of bone turnover after a short period of steroid therapy in elderly men","volume":"47","author":"Paglia","year":"2001","journal-title":"Clin. Chem."},{"issue":"2","key":"10.1016\/j.cytogfr.2023.03.002_bib123","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/BF03343976","article-title":"Effects of high doses of corticosteroids on bone metabolism","volume":"25","author":"Ardissone","year":"2002","journal-title":"J. Endocrinol. Invest"},{"issue":"10","key":"10.1016\/j.cytogfr.2023.03.002_bib124","doi-asserted-by":"crossref","first-page":"4923","DOI":"10.1210\/jc.2004-0164","article-title":"Immediate fall of bone formation and transient increase of bone resorption in the course of high-dose, short-term glucocorticoid therapy in young patients with multiple sclerosis","volume":"89","author":"Dovio","year":"2004","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"5","key":"10.1016\/j.cytogfr.2023.03.002_bib125","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1530\/eje.1.02147","article-title":"High-dose glucocorticoids increase serum levels of soluble IL-6 receptor alpha and its ratio to soluble gp130: an additional mechanism for early increased bone resorption","volume":"154","author":"Dovio","year":"2006","journal-title":"Eur. J. Endocrinol."},{"issue":"8","key":"10.1016\/j.cytogfr.2023.03.002_bib126","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1172\/JCI0214538","article-title":"Promotion of osteoclast survival and antagonism of bisphosphonate-induced osteoclast apoptosis by glucocorticoids","volume":"109","author":"Weinstein","year":"2002","journal-title":"J. Clin. Investig."},{"issue":"12","key":"10.1016\/j.cytogfr.2023.03.002_bib127","doi-asserted-by":"crossref","first-page":"5592","DOI":"10.1210\/en.2006-0459","article-title":"Glucocorticoids act directly on osteoclasts to increase their life span and reduce bone density","volume":"147","author":"Jia","year":"2006","journal-title":"Endocrinology"},{"issue":"8","key":"10.1016\/j.cytogfr.2023.03.002_bib128","doi-asserted-by":"crossref","first-page":"2152","DOI":"10.1172\/JCI28084","article-title":"Glucocorticoids suppress bone formation via the osteoclast","volume":"116","author":"Kim","year":"2006","journal-title":"J. Clin. Invest"},{"issue":"12","key":"10.1016\/j.cytogfr.2023.03.002_bib129","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1002\/jbmr.5650051206","article-title":"Glucocorticoids stimulate resorption in fetal rat parietal bones in vitro","volume":"5","author":"Gronowicz","year":"1990","journal-title":"J. Bone Min. Res"},{"issue":"3","key":"10.1016\/j.cytogfr.2023.03.002_bib130","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1359\/JBMR.041233","article-title":"Influence of glucocorticoids on human osteoclast generation and activity","volume":"20","author":"Sivagurunathan","year":"2005","journal-title":"J. Bone Min. Res"},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib131","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1677\/joe.0.1750155","article-title":"Effect of corticosteroids on human osteoclast formation and activity","volume":"175","author":"Hirayama","year":"2002","journal-title":"J. Endocrinol."},{"issue":"2","key":"10.1016\/j.cytogfr.2023.03.002_bib132","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1369\/00221554211063519","article-title":"Effects of alendronate and dexamethasone on osteoclast gene expression and bone resorption in mouse marrow cultures","volume":"70","author":"de Faria","year":"2022","journal-title":"J. Histochem Cytochem"},{"issue":"10","key":"10.1016\/j.cytogfr.2023.03.002_bib133","doi-asserted-by":"crossref","first-page":"2184","DOI":"10.1002\/jbmr.113","article-title":"Glucocorticoids maintain human osteoclasts in the active mode of their resorption cycle","volume":"25","author":"Soe","year":"2010","journal-title":"J. Bone Min. Res"},{"issue":"3","key":"10.1016\/j.cytogfr.2023.03.002_bib134","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1210\/endo-125-3-1290","article-title":"Glucocorticoids impair bone resorptive activity and viability of osteoclasts disaggregated from neonatal rat long bones","volume":"125","author":"Tobias","year":"1989","journal-title":"Endocrinology"},{"issue":"2","key":"10.1016\/j.cytogfr.2023.03.002_bib135","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1172\/JCI2799","article-title":"Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone","volume":"102","author":"Weinstein","year":"1998","journal-title":"J. Clin. Invest"},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib136","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1007\/s00223-020-00687-2","article-title":"Glucocorticoids enhanced osteoclast autophagy through the PI3K\/Akt\/mTOR signaling pathway","volume":"107","author":"Fu","year":"2020","journal-title":"Calcif. Tissue Int"},{"issue":"5","key":"10.1016\/j.cytogfr.2023.03.002_bib137","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1016\/j.devcel.2011.08.016","article-title":"Autophagy proteins regulate the secretory component of osteoclastic bone resorption","volume":"21","author":"DeSelm","year":"2011","journal-title":"Dev. Cell"},{"key":"10.1016\/j.cytogfr.2023.03.002_bib138","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.bone.2015.06.014","article-title":"Glucocorticoids: dose-related effects on osteoclast formation and function via reactive oxygen species and autophagy","volume":"79","author":"Shi","year":"2015","journal-title":"Bone"},{"issue":"6","key":"10.1016\/j.cytogfr.2023.03.002_bib139","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1136\/annrheumdis-2015-207240","article-title":"Inactivation of autophagy ameliorates glucocorticoid-induced and ovariectomy-induced bone loss","volume":"75","author":"Lin","year":"2016","journal-title":"Ann. Rheum. Dis."},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib140","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1038\/s41467-021-22131-1","article-title":"Osteoclasts protect bone blood vessels against senescence through the angiogenin\/plexin-B2 axis","volume":"12","author":"Liu","year":"2021","journal-title":"Nat. Commun."},{"issue":"2","key":"10.1016\/j.cytogfr.2023.03.002_bib141","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1002\/jbmr.320","article-title":"The amazing osteocyte","volume":"26","author":"Bonewald","year":"2011","journal-title":"J. Bone Min. Res"},{"issue":"5","key":"10.1016\/j.cytogfr.2023.03.002_bib142","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1210\/er.2012-1026","article-title":"The osteocyte: an endocrine cell. and more","volume":"34","author":"Dallas","year":"2013","journal-title":"Endocr. Rev."},{"issue":"2","key":"10.1016\/j.cytogfr.2023.03.002_bib143","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.bone.2013.01.034","article-title":"Glucocorticoids and osteocyte autophagy","volume":"54","author":"Yao","year":"2013","journal-title":"Bone"},{"issue":"6","key":"10.1016\/j.cytogfr.2023.03.002_bib144","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1093\/jmicro\/dfp032","article-title":"FGF23 is mainly synthesized by osteocytes in the regularly distributed osteocytic lacunar canalicular system established after physiological bone remodeling","volume":"58","author":"Ubaidus","year":"2009","journal-title":"J. Electron Microsc."},{"issue":"8","key":"10.1016\/j.cytogfr.2023.03.002_bib145","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.1096\/fj.10-177816","article-title":"Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling","volume":"25","author":"Martin","year":"2011","journal-title":"FASEB J."},{"issue":"3","key":"10.1016\/j.cytogfr.2023.03.002_bib146","doi-asserted-by":"crossref","first-page":"E587","DOI":"10.1152\/ajpendo.00219.2016","article-title":"Cortical bone loss caused by glucocorticoid excess requires RANKL production by osteocytes and is associated with reduced OPG expression in mice","volume":"311","author":"Piemontese","year":"2016","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib147","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1677\/joe.0.1590191","article-title":"Osteoprotegerin mRNA is expressed in primary human osteoblast-like cells: down-regulation by glucocorticoids","volume":"159","author":"Vidal","year":"1998","journal-title":"J. Endocrinol."},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib148","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1002\/jcb.21414","article-title":"Dexamethasone promotes osteoclastogenesis by inhibiting osteoprotegerin through multiple levels","volume":"103","author":"Kondo","year":"2008","journal-title":"J. Cell Biochem"},{"issue":"11","key":"10.1016\/j.cytogfr.2023.03.002_bib149","doi-asserted-by":"crossref","first-page":"2242","DOI":"10.1002\/jbmr.1688","article-title":"Selective glucocorticoid receptor modulation maintains bone mineral density in mice","volume":"27","author":"Thiele","year":"2012","journal-title":"J. Bone Min. Res"},{"issue":"8","key":"10.1016\/j.cytogfr.2023.03.002_bib150","doi-asserted-by":"crossref","first-page":"2385","DOI":"10.1002\/art.30385","article-title":"Sclerostin antibody treatment enhances bone strength but does not prevent growth retardation in young mice treated with dexamethasone","volume":"63","author":"Marenzana","year":"2011","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.cytogfr.2023.03.002_bib151","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.bone.2015.09.010","article-title":"Sclerostin antibody and interval treadmill training effects in a rodent model of glucocorticoid-induced osteopenia","volume":"81","author":"Achiou","year":"2015","journal-title":"Bone"},{"issue":"4","key":"10.1016\/j.cytogfr.2023.03.002_bib152","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1210\/en.2007-0910","article-title":"Modulation of Dickkopf-1 attenuates glucocorticoid induction of osteoblast apoptosis, adipocytic differentiation, and bone mass loss","volume":"149","author":"Wang","year":"2008","journal-title":"Endocrinology"},{"issue":"1","key":"10.1016\/j.cytogfr.2023.03.002_bib153","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.bone.2013.08.016","article-title":"Effect of glucocorticoid treatment on Wnt signalling antagonists (sclerostin and Dkk-1) and their relationship with bone turnover","volume":"57","author":"Gifre","year":"2013","journal-title":"Bone"},{"issue":"4","key":"10.1016\/j.cytogfr.2023.03.002_bib154","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1007\/s00223-012-9684-4","article-title":"Acute effects of glucocorticoids on serum markers of osteoclasts, osteoblasts, and osteocytes","volume":"92","author":"Brabnikova Maresova","year":"2013","journal-title":"Calcif. Tissue Int"},{"issue":"3","key":"10.1016\/j.cytogfr.2023.03.002_bib155","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1359\/JBMR.051103","article-title":"Glucocorticoid-treated mice have localized changes in trabecular bone material properties and osteocyte lacunar size that are not observed in placebo-treated or estrogen-deficient mice","volume":"21","author":"Lane","year":"2006","journal-title":"J. Bone Min. Res"},{"issue":"10","key":"10.1016\/j.cytogfr.2023.03.002_bib156","doi-asserted-by":"crossref","first-page":"3366","DOI":"10.1096\/fj.11-182519","article-title":"Glucocorticoid dose determines osteocyte cell fate","volume":"25","author":"Jia","year":"2011","journal-title":"FASEB J."},{"issue":"9","key":"10.1016\/j.cytogfr.2023.03.002_bib157","doi-asserted-by":"crossref","first-page":"3323","DOI":"10.1210\/en.2011-0170","article-title":"Osteoprotegerin prevents glucocorticoid-induced osteocyte apoptosis in mice","volume":"152","author":"Weinstein","year":"2011","journal-title":"Endocrinology"},{"issue":"6","key":"10.1016\/j.cytogfr.2023.03.002_bib158","doi-asserted-by":"crossref","first-page":"2641","DOI":"10.1210\/en.2009-1488","article-title":"Intermittent parathyroid hormone administration counteracts the adverse effects of glucocorticoids on osteoblast and osteocyte viability, bone formation, and strength in mice","volume":"151","author":"Weinstein","year":"2010","journal-title":"Endocrinology"},{"issue":"4","key":"10.1016\/j.cytogfr.2023.03.002_bib159","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1172\/JCI6610","article-title":"Increased bone formation by prevention of osteoblast apoptosis with parathyroid hormone","volume":"104","author":"Jilka","year":"1999","journal-title":"J. Clin. Invest"},{"issue":"10","key":"10.1016\/j.cytogfr.2023.03.002_bib160","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1172\/JCI6800","article-title":"Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin","volume":"104","author":"Plotkin","year":"1999","journal-title":"J. Clin. Invest"},{"issue":"2","key":"10.1016\/j.cytogfr.2023.03.002_bib161","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1038\/nrrheum.2009.259","article-title":"Management of glucocorticoid-induced osteoporosis","volume":"6","author":"Compston","year":"2010","journal-title":"Nat. Rev. Rheuma"},{"issue":"33","key":"10.1016\/j.cytogfr.2023.03.002_bib162","doi-asserted-by":"crossref","first-page":"24120","DOI":"10.1074\/jbc.M611435200","article-title":"Glucocorticoids induce osteocyte apoptosis by blocking focal adhesion kinase-mediated survival. Evidence for inside-out signaling leading to anoikis","volume":"282","author":"Plotkin","year":"2007","journal-title":"J. Biol. Chem."},{"issue":"7","key":"10.1016\/j.cytogfr.2023.03.002_bib163","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1210\/en.2019-00237","article-title":"Glucocorticoid-Induced Bone Fragility Is Prevented in Female Mice by Blocking Pyk2\/Anoikis Signaling","volume":"160","author":"Sato","year":"2019","journal-title":"Endocrinology"},{"issue":"11","key":"10.1016\/j.cytogfr.2023.03.002_bib164","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1002\/tox.23327","article-title":"Overexpression of HIF-1alpha enhances the protective effect of mitophagy on steroid-induced osteocytes apoptosis","volume":"36","author":"Xu","year":"2021","journal-title":"Environ. Toxicol."},{"issue":"11","key":"10.1016\/j.cytogfr.2023.03.002_bib165","doi-asserted-by":"crossref","first-page":"2479","DOI":"10.1002\/jbmr.160","article-title":"Glucocorticoid-induced autophagy in osteocytes","volume":"25","author":"Xia","year":"2010","journal-title":"J. Bone Min. Res"},{"key":"10.1016\/j.cytogfr.2023.03.002_bib166","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.bone.2015.02.005","article-title":"Suppression of autophagy in osteocytes does not modify the adverse effects of glucocorticoids on cortical bone","volume":"75","author":"Piemontese","year":"2015","journal-title":"Bone"},{"issue":"2","key":"10.1016\/j.cytogfr.2023.03.002_bib167","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1111\/j.1474-9726.2009.00545.x","article-title":"Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice","volume":"9","author":"Weinstein","year":"2010","journal-title":"Aging Cell"},{"issue":"19","key":"10.1016\/j.cytogfr.2023.03.002_bib168","doi-asserted-by":"crossref","first-page":"26966","DOI":"10.18632\/oncotarget.9034","article-title":"Glucocorticoid impairs cell-cell communication by autophagy-mediated degradation of connexin 43 in osteocytes","volume":"7","author":"Gao","year":"2016","journal-title":"Oncotarget"},{"issue":"9","key":"10.1016\/j.cytogfr.2023.03.002_bib169","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2022.105019","article-title":"Partial prevention of glucocorticoid-induced osteocyte deterioration in young male mice with osteocrin gene therapy","volume":"25","author":"Mazur","year":"2022","journal-title":"iScience"},{"key":"10.1016\/j.cytogfr.2023.03.002_bib170","first-page":"CD001347","article-title":"Bisphosphonates for steroid-induced osteoporosis","volume":"10","author":"Allen","year":"2016","journal-title":"Cochrane Database Syst. Rev."},{"issue":"2","key":"10.1016\/j.cytogfr.2023.03.002_bib171","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1002\/jbmr.5650110203","article-title":"A new model for the regulation of bone resorption, with particular reference to the effects of bisphosphonates","volume":"11","author":"Parfitt","year":"1996","journal-title":"J. Bone Min. Res"},{"issue":"8","key":"10.1016\/j.cytogfr.2023.03.002_bib172","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1172\/JCI3914","article-title":"Parathyroid hormone treatment can reverse corticosteroid-induced osteoporosis. Results of a randomized controlled clinical trial","volume":"102","author":"Lane","year":"1998","journal-title":"J. Clin. Invest"},{"issue":"11","key":"10.1016\/j.cytogfr.2023.03.002_bib173","doi-asserted-by":"crossref","first-page":"3346","DOI":"10.1002\/art.24879","article-title":"Effects of teriparatide versus alendronate for treating glucocorticoid-induced osteoporosis: thirty-six-month results of a randomized, double-blind, controlled trial","volume":"60","author":"Saag","year":"2009","journal-title":"Arthritis Rheum."},{"issue":"7","key":"10.1016\/j.cytogfr.2023.03.002_bib174","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1001\/jama.2016.11136","article-title":"A.S. investigators, effect of abaloparatide vs placebo on new vertebral fractures in postmenopausal women with osteoporosis: a Randomized clinical trial","volume":"316","author":"Miller","year":"2016","journal-title":"JAMA"},{"issue":"11","key":"10.1016\/j.cytogfr.2023.03.002_bib175","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1177\/1759720X18805759","article-title":"New and emerging concepts in the use of denosumab for the treatment of osteoporosis","volume":"10","author":"Lewiecki","year":"2018","journal-title":"Ther. Adv. Musculoskelet. Dis."}],"container-title":["Cytokine &amp; Growth Factor Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1359610123000114?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1359610123000114?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T11:01:47Z","timestamp":1761217307000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1359610123000114"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":175,"alternative-id":["S1359610123000114"],"URL":"https:\/\/doi.org\/10.1016\/j.cytogfr.2023.03.002","relation":{},"ISSN":["1359-6101"],"issn-type":[{"value":"1359-6101","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pathogenic mechanisms of glucocorticoid-induced osteoporosis","name":"articletitle","label":"Article Title"},{"value":"Cytokine & Growth Factor Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cytogfr.2023.03.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}