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Associations with core cognitive deficits of the dementia subtypes (i.e.,\u00a0visuospatial, sociocognitive, and semantic\u2010linguistic) were explored.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients showed significant apraxia compared with healthy controls but also disease\u2010specific praxis\u2010profiles. Using only the Dementia Apraxia Test, all four dementia subtypes could be correctly discriminated in 64.4% of cases, and in 78.2% when only distinguishing Alzheimer's disease versus frontotemporal lobar degeneration. Praxis\u2010profiles showed consistent associations with core cognitive impairments of the different dementia subtypes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>The Dementia Apraxia Test is a valid, time\u2010efficient and versatile cognitive marker to delineate variants of frontotemporal lobar degeneration and Alzheimer's disease in clinical routine, facilitating differential diagnoses of dementia subtypes in early disease stages.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.dadm.2018.04.002","type":"journal-article","created":{"date-parts":[[2018,5,16]],"date-time":"2018-05-16T00:28:50Z","timestamp":1526430530000},"page":"363-371","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Apraxia profiles\u2014A single cognitive marker to discriminate all variants of frontotemporal lobar degeneration and Alzheimer's 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