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We also assessed the relationship between SS\u2010OCT measurements and the severity of cognitive impairment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Peripapillary retinal nerve fiber layer and macular thickness were measured in 23 patients and 24 control subjects using SS\u2010OCT. Cognitive status was assessed using the Mini\u2010Mental State Examination, the Montreal Cognitive Assessment, and the Pfeffer Questionnaire.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Most inner retinal layer thickness parameters were significantly smaller in patients with MCI, especially macular ganglion cell complex thickness measurements. Mini\u2010Mental State Examination and Montreal Cognitive Assessment findings were significantly correlated with most macular thickness parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>The SS\u2010OCT\u2013measured inner retinal layers of patients with MCI displayed thinning, especially in the central macular area. SS\u2010OCT technology can provide useful information on ocular involvement patterns and holds promise as an ocular biomarker in this patient population.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.dadm.2019.08.006","type":"journal-article","created":{"date-parts":[[2019,9,25]],"date-time":"2019-09-25T17:54:35Z","timestamp":1569434075000},"page":"659-669","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Correlation between cognitive impairment and retinal neural loss assessed by swept\u2010source optical coherence tomography in patients with mild cognitive impairment"],"prefix":"10.1002","volume":"11","author":[{"given":"Ana L.M.","family":"Almeida","sequence":"first","affiliation":[{"name":"Department of Neurology Federal University of Juiz de Fora Medical School Juiz de Fora Minas Gerais Brazil"},{"name":"Department of Neurology Federal University of Juiz de Fora Medical School Juiz de Fora Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leopoldo A.","family":"Pires","sequence":"additional","affiliation":[{"name":"Department of Neurology Federal University of Juiz de Fora Medical School Juiz de Fora Minas Gerais Brazil"},{"name":"Department of Neurology Federal University of Juiz de Fora Medical School Juiz de Fora Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn A.","family":"Figueiredo","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Federal University of Juiz de Fora Medical School Juiz de Fora Minas Gerais Brazil"},{"name":"Department of Ophthalmology Federal University of Juiz de Fora Medical School Juiz de Fora Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciana V.F.","family":"Costa\u2010Cunha","sequence":"additional","affiliation":[{"name":"Juiz de Fora Eye Hospital Juiz de Fora Minas Gerais Brazil"},{"name":"Juiz de Fora Eye Hospital Juiz de Fora Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leandro C.","family":"Zacharias","sequence":"additional","affiliation":[{"name":"Division of Ophthalmology University of S\u00e3o Paulo Medical School S\u00e3o Paulo Brazil"},{"name":"Division of Ophthalmology University of Sao Paulo Medical School Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rony C.","family":"Preti","sequence":"additional","affiliation":[{"name":"Division of Ophthalmology University of S\u00e3o Paulo Medical School S\u00e3o Paulo Brazil"},{"name":"Division of Ophthalmology University of Sao Paulo Medical School Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rio L.R.","family":"Monteiro","sequence":"additional","affiliation":[{"name":"Division of Ophthalmology University of S\u00e3o Paulo Medical School S\u00e3o Paulo Brazil"},{"name":"Division of Ophthalmology University of Sao Paulo Medical School Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo P.","family":"Cunha","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Federal University of Juiz de Fora Medical School Juiz de Fora Minas Gerais Brazil"},{"name":"Department of Ophthalmology Federal University of Juiz de Fora Medical School Juiz de Fora Minas Gerais Brazil"},{"name":"Juiz de Fora Eye Hospital Juiz de Fora Minas Gerais Brazil"},{"name":"Juiz de Fora Eye Hospital Juiz de Fora Minas Gerais Brazil"},{"name":"Division of Ophthalmology University of S\u00e3o Paulo Medical School S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,12]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)11920-9"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2008.01326.x"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000252358.03285.9d"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2011.09.032"},{"key":"e_1_2_6_6_2","first-page":"116","article-title":"Optical coherence tomography for macula diagnostics. 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