{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T17:33:17Z","timestamp":1782495197502,"version":"3.54.5"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science KAKENHI","doi-asserted-by":"crossref","award":["26450286"],"award-info":[{"award-number":["26450286"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science KAKENHI","doi-asserted-by":"crossref","award":["17K07939"],"award-info":[{"award-number":["17K07939"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science KAKENHI","doi-asserted-by":"crossref","award":["16H04984"],"award-info":[{"award-number":["16H04984"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental &amp; Comparative Immunology"],"published-print":{"date-parts":[[2019,4]]},"DOI":"10.1016\/j.dci.2018.12.009","type":"journal-article","created":{"date-parts":[[2018,12,20]],"date-time":"2018-12-20T21:01:04Z","timestamp":1545339664000},"page":"37-44","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Generation of virus-specific CD8+ T cells by vaccination with inactivated virus in the intestine of ginbuna crucian carp"],"prefix":"10.1016","volume":"93","author":[{"given":"Seisuke","family":"Tajimi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masakazu","family":"Kondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teruyuki","family":"Nakanishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Nagasawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6350-7552","authenticated-orcid":false,"given":"Miki","family":"Nakao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomonori","family":"Somamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.dci.2018.12.009_bib1","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.dci.2013.12.009","article-title":"Modulation of genes related to the recruitment of immune cells in the digestive tract of trout experimentally infected with infectious pancreatic necrosis virus (IPNV) or orally vaccinated","volume":"44","author":"Ballesteros","year":"2014","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib2","doi-asserted-by":"crossref","first-page":"3361","DOI":"10.1002\/1521-4141(200111)31:11<3361::AID-IMMU3361>3.0.CO;2-Z","article-title":"Abundance of unconventional CD8(+) natural killer T cells in the large intestine","volume":"31","author":"Bannai","year":"2001","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib3","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.it.2004.09.005","article-title":"Let's go mucosal: communication on slippery ground","volume":"25","author":"Brandtzaeg","year":"2004","journal-title":"Trends Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib4","first-page":"377","volume":"vol. 171","author":"Carbone","year":"1990"},{"key":"10.1016\/j.dci.2018.12.009_bib5","doi-asserted-by":"crossref","first-page":"2209","DOI":"10.4049\/jimmunol.1000347","article-title":"MHC class I presentation and regulation by IFN in bony fish determined by molecular analysis of the class I locus in grass carp","volume":"185","author":"Chen","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib6","doi-asserted-by":"crossref","first-page":"3668","DOI":"10.4049\/jimmunol.1600229","article-title":"The structure of the MHC class I molecule of bony fishes provides insights into the conserved nature of the antigen-presenting system","volume":"199","author":"Chen","year":"2017","journal-title":"J. Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib7","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.4049\/jimmunol.1500322","article-title":"Identification of teleost skin CD8\u03b1+ dendritic-like cells, representing a potential common ancestor for mammalian cross-presenting dendritic ells","volume":"195","author":"Granja","year":"2015","journal-title":"J. Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib8","doi-asserted-by":"crossref","first-page":"6","DOI":"10.3390\/biology5010006","article-title":"MHC and evolution in teleosts","volume":"5","author":"Grimholt","year":"2016","journal-title":"Biology"},{"key":"10.1016\/j.dci.2018.12.009_bib9","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1038\/nri3254","article-title":"Cross-presentation by dendritic cells","volume":"12","author":"Joffre","year":"2012","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib10","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.fsi.2014.08.005","article-title":"Immune gene expressions in grouper larvae (Epinephelus coioides) induced by bath and oral vaccinations with inactivated betanodavirus","volume":"40","author":"Kai","year":"2014","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib11","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.3389\/fimmu.2017.01281","article-title":"Intestinal barrier interactions with specialized CD8 T cells","volume":"8","author":"Konjar","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib12","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.3389\/fimmu.2018.01321","article-title":"Peculiar expression of CD3-epsilon in kidney of ginbuna crucian carp","volume":"9","author":"Miyazawa","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib13","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.1016\/j.vaccine.2013.02.008","article-title":"The kinetics of CD4+ and CD8+ T-cell gene expression correlate with protection in Atlantic salmon (Salmo salar L) vaccinated against infectious pancreatic necrosis","volume":"31","author":"Munang\u2019andu","year":"2013","journal-title":"Vaccine"},{"key":"10.1016\/j.dci.2018.12.009_bib14","doi-asserted-by":"crossref","first-page":"427","DOI":"10.3389\/fimmu.2015.00427","article-title":"A Review of the immunological mechanisms following mucosal vaccination of Finfish","volume":"6","author":"Munang\u2019andu","year":"2015","journal-title":"Front. Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib15","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0145-305X(98)00042-1","article-title":"The graft-versus-host reaction (GVHR) in the ginbuna crucian carp, Carassius auratus langsdorfii","volume":"23","author":"Nakanishi","year":"1999","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib16","doi-asserted-by":"crossref","first-page":"640","DOI":"10.3390\/biology4040640","article-title":"T cells in fish","volume":"4","author":"Nakanishi","year":"2015","journal-title":"Biology"},{"key":"10.1016\/j.dci.2018.12.009_bib17","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.dci.2012.07.004","article-title":"Immunogenicity and protective effects of inactivated Singapore grouper iridovirus (SGIV) vaccines in orange-spotted grouper, Epinephelus coioides","volume":"38","author":"Ou-yang","year":"2012","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib18","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.fsi.2010.09.001","article-title":"Teleost intestinal immunology","volume":"31","author":"Rombout","year":"2011","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib19","doi-asserted-by":"crossref","first-page":"525","DOI":"10.3390\/biology4030525","article-title":"The mucosal immune system of teleost fish","volume":"4","author":"Salinas","year":"2015","journal-title":"Biology"},{"key":"10.1016\/j.dci.2018.12.009_bib20","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.fsi.2007.11.009","article-title":"Characterization of the cell-mediated cytotoxic responses of isogeneic ginbuna crucian carp induced by oral immunisation with hapten-modified cellular antigens","volume":"24","author":"Sato","year":"2008","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib21","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.fsi.2010.04.017","article-title":"Induction of virus-specific cell-mediated cytotoxic responses of isogeneic ginbuna crucian carp, after oral immunization with inactivated virus","volume":"29","author":"Sato","year":"2010","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib22","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.fsi.2004.11.010","article-title":"Systemic priming of alloreactive cytotoxic cells in carp, following anal administration of allogeneic cell antigens","volume":"19","author":"Sato","year":"2005","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib23","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.molimm.2014.02.001","article-title":"Induction of rainbow trout MH class I and accessory proteins by viral haemorrhagic septicaemia virus","volume":"59","author":"Sever","year":"2014","journal-title":"Mol. Immunol."},{"issue":"9","key":"10.1016\/j.dci.2018.12.009_bib24","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3389\/fimmu.2018.00059","article-title":"Identification of a potential common ancestor for mammalian cross-presenting dendritic cells in teleost respiratory surfaces","volume":"25","author":"Soleto","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib38","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1006\/viro.2002.1486","article-title":"Role of specific cell-mediated cytotoxicity in protecting fish from viral infections","volume":"297","author":"Somamoto","year":"2002","journal-title":"Virology"},{"key":"10.1016\/j.dci.2018.12.009_bib25","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.virol.2009.04.008","article-title":"In vitro generation of viral-antigen dependent cytotoxic T-cells from ginbuna crucian carp, carassius auratus langsdorfii","volume":"389","author":"Somamoto","year":"2009","journal-title":"Virology"},{"key":"10.1016\/j.dci.2018.12.009_bib26","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.dci.2012.11.001","article-title":"Identification of anti-viral cytotoxic effector cells in the ginbuna crucian carp, carassius auratus langsdorfii","volume":"39","author":"Somamoto","year":"2013","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib27","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.dci.2013.07.014","article-title":"Antiviral functions of CD8 cytotoxic T cells in teleost fish","volume":"43","author":"Somamoto","year":"2014","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib28","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.dci.2015.04.016","article-title":"Local and systemic adaptive immune responses toward viral infection via gills in ginbuna crucian carp","volume":"52","author":"Somamoto","year":"2015","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib29","doi-asserted-by":"crossref","first-page":"15818","DOI":"10.1073\/pnas.2636938100","article-title":"Antigen-driven effector CD8 T cell function regulated by T-bet","volume":"100","author":"Sullivan","year":"2003","journal-title":"Proc. Natl. Acad. Sci. Unit. States Am."},{"key":"10.1016\/j.dci.2018.12.009_bib30","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/S0092-8674(00)80702-3","article-title":"A novel transcription factor, T-bet, directs Th1 lineage commitment","volume":"100","author":"Szabo","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.dci.2018.12.009_bib31","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.dci.2016.02.019","article-title":"T cell immunity in the teleost digestive tract","volume":"64","author":"Tafalla","year":"2016","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib32","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.dci.2011.01.013","article-title":"Conservation of characteristics and functions of CD4 positive lymphocytes in a teleost fish","volume":"35","author":"Toda","year":"2011","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib33","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1007\/s00251-017-1009-3","article-title":"MHC and adaptive immunity in teleost fishes","volume":"69","author":"Wilson","year":"2017","journal-title":"Immunogenetics"},{"key":"10.1016\/j.dci.2018.12.009_bib34","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.fsi.2013.11.016","article-title":"Role of CD4+ and CD8\u03b1+ T cells in protective immunity against Edwardsiella tarda infection of ginbuna crucian carp, Carassius auratus langsdorfii","volume":"36","author":"Yamasaki","year":"2014","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib35","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.fsi.2015.04.038","article-title":"Comparative analysis of adaptive immune response after vaccine trials using live attenuated and formalin-killed cells of Edwardsiella tarda in ginbuna crucian carp (Carassius auratus langsdorfii)","volume":"45","author":"Yamasaki","year":"2015","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib36","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.fsi.2017.09.051","article-title":"Functional activities of interferon gamma in large yellow croaker Larimichthys crocea","volume":"70","author":"Yang","year":"2017","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2018.12.009_bib37","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0065-2776(08)60262-X","article-title":"MHC-restricted cytotoxic T cells: studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness","volume":"27","author":"Zinkernagel","year":"1979","journal-title":"Adv. Immunol."}],"container-title":["Developmental &amp; Comparative Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145305X18304695?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145305X18304695?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,12]],"date-time":"2019-01-12T02:50:00Z","timestamp":1547261400000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0145305X18304695"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":38,"alternative-id":["S0145305X18304695"],"URL":"https:\/\/doi.org\/10.1016\/j.dci.2018.12.009","relation":{},"ISSN":["0145-305X"],"issn-type":[{"value":"0145-305X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Generation of virus-specific CD8+ T cells by vaccination with inactivated virus in the intestine of ginbuna crucian carp","name":"articletitle","label":"Article Title"},{"value":"Developmental & Comparative Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dci.2018.12.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}