{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T09:25:42Z","timestamp":1780392342594,"version":"3.54.1"},"reference-count":70,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U1402224"],"award-info":[{"award-number":["U1402224"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31700155"],"award-info":[{"award-number":["31700155"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Yunnan Province","award":["2016FB018"],"award-info":[{"award-number":["2016FB018"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental &amp; Comparative Immunology"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1016\/j.dci.2019.02.014","type":"journal-article","created":{"date-parts":[[2019,2,25]],"date-time":"2019-02-25T11:46:47Z","timestamp":1551095207000},"page":"27-36","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Molecular identification and antiviral function of the guanylate-binding protein (GBP) genes in the Chinese tree shrew (Tupaia belangeri chinesis)"],"prefix":"10.1016","volume":"96","author":[{"given":"Tianle","family":"Gu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dandan","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Lin","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2955-0693","authenticated-orcid":false,"given":"Yong-Gang","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.dci.2019.02.014_bib1","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.cell.2006.02.015","article-title":"Pathogen recognition and innate immunity","volume":"124","author":"Akira","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.dci.2019.02.014_bib2","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1006\/viro.1999.9614","article-title":"Interferon-induced guanylate binding protein-1 (GBP-1) mediates an antiviral effect against vesicular stomatitis virus and encephalomyocarditis virus","volume":"256","author":"Anderson","year":"1999","journal-title":"Virology"},{"key":"10.1016\/j.dci.2019.02.014_bib3","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.chom.2017.06.005","article-title":"Viral replication complexes are targeted by LC3-guided interferon-inducible GTPases","volume":"22","author":"Biering","year":"2017","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.dci.2019.02.014_bib4","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1038\/nrd2422","article-title":"Interferons at age 50: past, current and future impact on biomedicine","volume":"6","author":"Borden","year":"2007","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.dci.2019.02.014_bib5","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0014246","article-title":"Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner","volume":"5","author":"Britzen-Laurent","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.dci.2019.02.014_bib6","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1007\/s00705-004-0489-2","article-title":"Inhibition of VSV and EMCV replication by the interferon-induced GTPase, mGBP-2: differential requirement for wild-type GTP binding domain","volume":"150","author":"Carter","year":"2005","journal-title":"Arch. Virol."},{"key":"10.1016\/j.dci.2019.02.014_bib7","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1080\/21541248.2016.1213090","article-title":"Quo vadis? Interferon-inducible GTPases go to their target membranes via the LC3-conjugation system of autophagy","volume":"8","author":"Choi","year":"2016","journal-title":"Small GTPases"},{"key":"10.1016\/j.dci.2019.02.014_bib8","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/j.immuni.2014.05.006","article-title":"The parasitophorous vacuole membrane of Toxoplasma gondii is targeted for disruption by ubiquitin-like conjugation systems of autophagy","volume":"40","author":"Choi","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.dci.2019.02.014_bib9","doi-asserted-by":"crossref","first-page":"7729","DOI":"10.4049\/jimmunol.179.11.7729","article-title":"Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense","volume":"179","author":"Degrandi","year":"2007","journal-title":"J. Immunol."},{"key":"10.1016\/j.dci.2019.02.014_bib10","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1093\/nar\/gkh340","article-title":"MUSCLE: multiple sequence alignment with high accuracy and high throughput","volume":"32","author":"Edgar","year":"2004","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dci.2019.02.014_bib11","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1038\/ncomms2416","article-title":"Genome of the Chinese tree shrew","volume":"4","author":"Fan","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.dci.2019.02.014_bib12","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.3233\/JAD-170594","article-title":"Does the genetic feature of the Chinese tree shrew (Tupaia belangeri chinensis) support its potential as a viable model for alzheimer's disease research?","volume":"61","author":"Fan","year":"2018","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.dci.2019.02.014_bib13","doi-asserted-by":"crossref","first-page":"7145","DOI":"10.1038\/srep07145","article-title":"Tree shrew database (TreeshrewDB): a genomic knowledge base for the Chinese tree shrew","volume":"4","author":"Fan","year":"2014","journal-title":"Sci. Rep."},{"key":"10.1016\/j.dci.2019.02.014_bib14","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1159\/000460294","article-title":"Inducible GBP5 mediates the antiviral response via interferon-related pathways during influenza A virus infection","author":"Feng","year":"2017","journal-title":"J. Innate Immun."},{"key":"10.1016\/j.dci.2019.02.014_bib15","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.immuni.2013.05.007","article-title":"Cytosolic sensing of viruses","volume":"38","author":"Goubau","year":"2013","journal-title":"Immunity"},{"key":"10.1016\/j.dci.2019.02.014_bib16","doi-asserted-by":"crossref","DOI":"10.1007\/s00253-019-09615-3","article-title":"Establishment and characterization of an immortalized renal cell line of the Chinese tree shrew (Tupaia belangeri chinesis)","author":"Gu","year":"2019","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.dci.2019.02.014_bib17","first-page":"25","article-title":"Animal models for the study of hepatitis B virus infection","volume":"39","author":"Guo","year":"2018","journal-title":"Zool. Res."},{"key":"10.1016\/j.dci.2019.02.014_bib18","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1080\/21541248.2016.1189990","article-title":"Guanylate binding protein 5: impairing virion infectivity by targeting retroviral envelope glycoproteins","volume":"8","author":"Hotter","year":"2017","journal-title":"Small GTPases"},{"key":"10.1016\/j.dci.2019.02.014_bib19","doi-asserted-by":"crossref","first-page":"6456","DOI":"10.4049\/jimmunol.1003691","article-title":"Guanylate binding protein 4 negatively regulates virus-induced type I IFN and antiviral response by targeting IFN regulatory factor 7","volume":"187","author":"Hu","year":"2011","journal-title":"J. Immunol."},{"key":"10.1016\/j.dci.2019.02.014_bib20","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1002\/hep.23195","article-title":"Antiviral effects of the interferon-induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein","volume":"50","author":"Itsui","year":"2009","journal-title":"Hepatology"},{"key":"10.1016\/j.dci.2019.02.014_bib21","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.gene.2018.07.025","article-title":"Conserved structure and function of chemokine CXCL8 between Chinese tree shrews and humans","volume":"677","author":"Jiang","year":"2018","journal-title":"Gene"},{"key":"10.1016\/j.dci.2019.02.014_bib22","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/j.chom.2012.09.007","article-title":"IFN-inducible GTPases in host cell defense","volume":"12","author":"Kim","year":"2012","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.dci.2019.02.014_bib23","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1126\/science.1201711","article-title":"A family of IFN-gamma-inducible 65-kD GTPases protects against bacterial infection","volume":"332","author":"Kim","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.dci.2019.02.014_bib24","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.chom.2016.02.019","article-title":"Guanylate binding protein (GBP) 5 is an interferon-inducible inhibitor of HIV-1 infectivity","volume":"19","author":"Krapp","year":"2016","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.dci.2019.02.014_bib25","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.11479","article-title":"Guanylate binding proteins directly attack Toxoplasma gondii via supramolecular complexes","volume":"5","author":"Kravets","year":"2016","journal-title":"Elife"},{"key":"10.1016\/j.dci.2019.02.014_bib26","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1038\/cr.2016.156","article-title":"Long-term propagation of tree shrew spermatogonial stem cells in culture and successful generation of transgenic offspring","volume":"27","author":"Li","year":"2017","journal-title":"Cell Res."},{"key":"10.1016\/j.dci.2019.02.014_bib27","first-page":"485","article-title":"Experimental infection of tree shrews (Tupaia belangeri) with Coxsackie virus A16","volume":"35","author":"Li","year":"2014","journal-title":"Zool. Res."},{"key":"10.1016\/j.dci.2019.02.014_bib28","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s13365-015-0393-4","article-title":"Reactivation of HSV-1 following explant of tree shrew brain","volume":"22","author":"Li","year":"2016","journal-title":"J. Neurovirol."},{"key":"10.1016\/j.dci.2019.02.014_bib29","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1128\/JVI.02258-15","article-title":"Herpes simplex virus 1 infection of tree shrews differs from that of mice in the severity of acute infection and viral transcription in the peripheral nervous system","volume":"90","author":"Li","year":"2016","journal-title":"J. Virol."},{"key":"10.1016\/j.dci.2019.02.014_bib30","doi-asserted-by":"crossref","first-page":"4412","DOI":"10.1128\/JVI.02718-15","article-title":"Guanylate-binding protein 1, an interferon-induced GTPase, exerts an antiviral activity against classical swine fever virus depending on its GTPase activity","volume":"90","author":"Li","year":"2016","journal-title":"J. Virol."},{"key":"10.1016\/j.dci.2019.02.014_bib31","doi-asserted-by":"crossref","first-page":"S2272","DOI":"10.21037\/jtd.2017.12.121","article-title":"The tree shrew as a model for infectious diseases research","volume":"10","author":"Li","year":"2018","journal-title":"J. Thorac. Dis."},{"key":"10.1016\/j.dci.2019.02.014_bib32","first-page":"193","article-title":"Antiviral effect of interferon-induced guanylate binding protein-1 against coxsackie virus and hepatitis B virus B3 in vitro","volume":"22","author":"Lu","year":"2008","journal-title":"Virol. Sin."},{"key":"10.1016\/j.dci.2019.02.014_bib33","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.gene.2017.12.060","article-title":"Molecular cloning and characterization of APOBEC3 family in tree shrew","volume":"646","author":"Luo","year":"2018","journal-title":"Gene"},{"key":"10.1016\/j.dci.2019.02.014_bib34","first-page":"58","article-title":"In vivo genome editing thrives with diversified CRISPR technologies","volume":"39","author":"Ma","year":"2018","journal-title":"Zool. Res."},{"key":"10.1016\/j.dci.2019.02.014_bib35","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.it.2004.08.010","article-title":"IFN-inducible GTPases and immunity to intracellular pathogens","volume":"25","author":"MacMicking","year":"2004","journal-title":"Trends Immunol."},{"key":"10.1016\/j.dci.2019.02.014_bib36","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/nri3787","article-title":"Type I interferons in infectious disease","volume":"15","author":"McNab","year":"2015","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.dci.2019.02.014_bib37","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/cmi.12546","article-title":"Interferon-inducible GTPases in cell autonomous and innate immunity","volume":"18","author":"Meunier","year":"2016","journal-title":"Cell Microbiol."},{"key":"10.1016\/j.dci.2019.02.014_bib38","doi-asserted-by":"crossref","first-page":"2985","DOI":"10.1093\/molbev\/msu238","article-title":"Independent birth of a novel TRIMCyp in Tupaia belangeri with a divergent function from its paralog TRIM5","volume":"31","author":"Mu","year":"2014","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.dci.2019.02.014_bib39","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1096\/fj.11-189886","article-title":"A new splice variant of the human guanylate-binding protein 3 mediates anti-influenza activity through inhibition of viral transcription and replication","volume":"26","author":"Nordmann","year":"2012","journal-title":"FASEB J."},{"key":"10.1016\/j.dci.2019.02.014_bib40","doi-asserted-by":"crossref","first-page":"W267","DOI":"10.1093\/nar\/gkw407","article-title":"Breaking-Cas-interactive design of guide RNAs for CRISPR-Cas experiments for ENSEMBL genomes","volume":"44","author":"Oliveros","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dci.2019.02.014_bib41","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1089\/jir.2006.26.328","article-title":"In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters","volume":"26","author":"Olszewski","year":"2006","journal-title":"J. Interferon Cytokine Res."},{"key":"10.1016\/j.dci.2019.02.014_bib42","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1080\/15548627.2016.1178447","article-title":"Targeting by AutophaGy proteins (TAG): targeting of IFNG-inducible GTPases to membranes by the LC3 conjugation system of autophagy","volume":"12","author":"Park","year":"2016","journal-title":"Autophagy"},{"key":"10.1016\/j.dci.2019.02.014_bib43","doi-asserted-by":"crossref","first-page":"3495","DOI":"10.1016\/j.jmb.2016.04.032","article-title":"Interferon-inducible GTPases in host resistance, inflammation and disease","volume":"428","author":"Pilla-Moffett","year":"2016","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.dci.2019.02.014_bib44","doi-asserted-by":"crossref","first-page":"2281","DOI":"10.1038\/nprot.2013.143","article-title":"Genome engineering using the CRISPR-Cas9 system","volume":"8","author":"Ran","year":"2013","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.dci.2019.02.014_bib45","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1146\/annurev-immunol-032713-120231","article-title":"Interferon-stimulated genes: a complex web of host defenses","volume":"32","author":"Schneider","year":"2014","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.dci.2019.02.014_bib46","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1093\/molbev\/mst197","article-title":"MEGA6: molecular evolutionary genetics analysis version 6.0","volume":"30","author":"Tamura","year":"2013","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.dci.2019.02.014_bib47","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1089\/jir.2007.0086","article-title":"Unique features of different members of the human guanylate-binding protein family","volume":"27","author":"Tripal","year":"2007","journal-title":"J. Interferon Cytokine Res."},{"key":"10.1016\/j.dci.2019.02.014_bib48","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1538\/expanim.14-0007","article-title":"Tupaia belangeri as an experimental animal model for viral infection","volume":"63","author":"Tsukiyama-Kohara","year":"2014","journal-title":"Exp. Anim."},{"key":"10.1016\/j.dci.2019.02.014_bib49","first-page":"1","article-title":"Hepatitis B virus infection of tupaia hepatocytes in vitro and in vivo","volume":"24","author":"Walter","year":"1996","journal-title":"Hepatology"},{"key":"10.1016\/j.dci.2019.02.014_bib50","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.chom.2017.09.007","article-title":"GBPs inhibit motility of shigella flexneri but are targeted for degradation by the bacterial ubiquitin ligase IpaH9.8","volume":"22","author":"Wandel","year":"2017","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.dci.2019.02.014_bib51","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1186\/1743-422X-9-170","article-title":"Experimental chronic hepatitis B infection of neonatal tree shrews (Tupaia belangeri chinensis): a model to study molecular causes for susceptibility and disease progression to chronic hepatitis in humans","volume":"9","author":"Wang","year":"2012","journal-title":"Virol. J."},{"key":"10.1016\/j.dci.2019.02.014_bib52","first-page":"96","article-title":"Dynamic changes in DNA demethylation in the tree shrew (Tupaia belangeri chinensis) brain during postnatal development and aging","volume":"38","author":"Wei","year":"2017","journal-title":"Zool. Res."},{"key":"10.1016\/j.dci.2019.02.014_bib53","first-page":"127","article-title":"Tree shrew (Tupaia belangeri) as a novel laboratory disease animal model","volume":"38","author":"Xiao","year":"2017","journal-title":"Zool. Res."},{"key":"10.1016\/j.dci.2019.02.014_bib54","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1006\/viro.1998.9127","article-title":"Transmission of hepatitis C virus infection to tree shrews","volume":"244","author":"Xie","year":"1998","journal-title":"Virology"},{"key":"10.1016\/j.dci.2019.02.014_bib55","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.jgg.2017.09.007","article-title":"Efficient genetic manipulation in the developing brain of tree shrew using in utero electroporation and virus infection","volume":"44","author":"Xu","year":"2017","journal-title":"J. Genet. Genomics."},{"key":"10.1016\/j.dci.2019.02.014_bib56","doi-asserted-by":"crossref","first-page":"70","DOI":"10.3724\/SP.J.1141.2013.02070","article-title":"Molecular evidence on the phylogenetic position of tree shrews","volume":"34","author":"Xu","year":"2013","journal-title":"Zool. Res."},{"key":"10.1016\/j.dci.2019.02.014_bib57","doi-asserted-by":"crossref","first-page":"10950","DOI":"10.1073\/pnas.1604939113","article-title":"Loss of RIG-I leads to a functional replacement with MDA5 in the Chinese tree shrew","volume":"113","author":"Xu","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.dci.2019.02.014_bib58","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.dci.2015.04.014","article-title":"Characterization of a MAVS ortholog from the Chinese tree shrew (Tupaia belangeri chinensis)","volume":"52","author":"Xu","year":"2015","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2019.02.014_bib59","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3724\/SP.J.1141.2013.02059","article-title":"Tree shrews under the spot light: emerging model of human diseases","volume":"34","author":"Xu","year":"2013","journal-title":"Zool. Res."},{"key":"10.1016\/j.dci.2019.02.014_bib60","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.immuni.2012.06.009","article-title":"A cluster of interferon-\u03b3-inducible p65 GTPases plays a critical role in host defense against toxoplasma gondii","volume":"37","author":"Yamamoto","year":"2012","journal-title":"Immunity"},{"key":"10.1016\/j.dci.2019.02.014_bib61","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/BF01261404","article-title":"Human hepatitis B virus and hepatocellular carcinoma. I. experimental infection of tree shrews with hepatitis B virus","volume":"122","author":"Yan","year":"1996","journal-title":"J. Canc. Res. Clin. Oncol."},{"key":"10.1016\/j.dci.2019.02.014_bib62","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1186\/1743-422X-10-111","article-title":"The tree shrew provides a useful alternative model for the study of influenza H1N1 virus","volume":"10","author":"Yang","year":"2013","journal-title":"Virol. J."},{"key":"10.1016\/j.dci.2019.02.014_bib63","first-page":"118","article-title":"Creating animal models, why not use the Chinese tree shrew (Tupaia belangeri chinensis)?","volume":"38","author":"Yao","year":"2017","journal-title":"Zool. Res."},{"key":"10.1016\/j.dci.2019.02.014_bib64","doi-asserted-by":"crossref","DOI":"10.1016\/j.cyto.2018.11.009","article-title":"Molecular characterization of the 2',5'-oligoadenylate synthetase family in the Chinese tree shrew (Tupaia belangeri chinensis)","author":"Yao","year":"2019","journal-title":"Cytokine"},{"key":"10.1016\/j.dci.2019.02.014_bib65","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.dci.2016.02.025","article-title":"Identification and characterization of toll-like receptors (TLRs) in the Chinese tree shrew (Tupaia belangeri chinensis)","volume":"60","author":"Yu","year":"2016","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2019.02.014_bib66","article-title":"Diverse interleukin-7 mRNA transcripts in Chinese tree shrew (Tupaia belangeri chinensis)","volume":"9","author":"Yu","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.dci.2019.02.014_bib67","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1007\/s00705-006-0930-9","article-title":"Genomic analysis of two porcine encephalomyocarditis virus strains isolated in China","volume":"152","author":"Zhang","year":"2007","journal-title":"Arch. Virol."},{"key":"10.1016\/j.dci.2019.02.014_bib68","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.immuni.2014.01.010","article-title":"NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING","volume":"40","author":"Zhang","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.dci.2019.02.014_bib69","series-title":"Basic Biology and Disease Models of Tree Shrews","author":"Zheng","year":"2014"},{"key":"10.1016\/j.dci.2019.02.014_bib70","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.00632-17","article-title":"Guanylate-binding protein 1 inhibits nuclear delivery of kaposi's sarcoma-associated herpesvirus virions by disrupting formation of actin filament","volume":"91","author":"Zou","year":"2017","journal-title":"J. Virol."}],"container-title":["Developmental &amp; Comparative Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145305X18306268?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145305X18306268?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T11:48:37Z","timestamp":1565178517000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0145305X18306268"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":70,"alternative-id":["S0145305X18306268"],"URL":"https:\/\/doi.org\/10.1016\/j.dci.2019.02.014","relation":{},"ISSN":["0145-305X"],"issn-type":[{"value":"0145-305X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Molecular identification and antiviral function of the guanylate-binding protein (GBP) genes in the Chinese tree shrew (Tupaia belangeri chinesis)","name":"articletitle","label":"Article Title"},{"value":"Developmental & Comparative Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dci.2019.02.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}