{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T03:20:08Z","timestamp":1784863208003,"version":"3.55.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,15]],"date-time":"2025-02-15T00:00:00Z","timestamp":1739577600000},"content-version":"am","delay-in-days":290,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["IOS-2103367"],"award-info":[{"award-number":["IOS-2103367"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental & Comparative Immunology"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.dci.2024.105149","type":"journal-article","created":{"date-parts":[[2024,2,8]],"date-time":"2024-02-08T12:27:32Z","timestamp":1707395252000},"page":"105149","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["A family of olfactory receptors uniquely expanded in marsupial and monotreme genomes are expressed by a T cell subset also unique to marsupials and monotremes"],"prefix":"10.1016","volume":"154","author":[{"given":"Jordan M.","family":"Sampson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly A.","family":"Morrissey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel C.","family":"Douek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8479-8819","authenticated-orcid":false,"given":"Robert D.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.dci.2024.105149_bib1","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0022-2836(05)80360-2","article-title":"Basic local alignment search tool","volume":"215","author":"Altschul","year":"1990","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.dci.2024.105149_bib2","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1038\/nature05634","article-title":"The delayed rise of present-day mammals","volume":"446","author":"Bininda-Emonds","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.dci.2024.105149_bib3","author":"Blighe"},{"key":"10.1016\/j.dci.2024.105149_bib4","author":"Buck","year":"1991"},{"key":"10.1016\/j.dci.2024.105149_bib5","doi-asserted-by":"crossref","first-page":"2104","DOI":"10.1002\/jcp.25929","article-title":"The diversified function and potential therapy of ectopic olfactory receptors in non\u2010olfactory tissues","volume":"233","author":"Chen","year":"2018","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.dci.2024.105149_bib6","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1189\/jlb.1A0914-425RR","article-title":"Odorants specifically modulate chemotaxis and tissue retention of CD4+ T cells via cyclic adenosine monophosphate induction","volume":"100","author":"Clark","year":"2016","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.dci.2024.105149_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2164-7-121","article-title":"Widespread ectopic expression of olfactory receptor genes","volume":"7","author":"Feldmesser","year":"2006","journal-title":"BMC Genom."},{"key":"10.1016\/j.dci.2024.105149_bib8","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1007\/BF01734359","article-title":"Evolutionary trees from DNA sequences: a maximum likelihood approach","volume":"17","author":"Felsenstein","year":"1981","journal-title":"J. Mol. Evol."},{"key":"10.1016\/j.dci.2024.105149_bib9","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1007\/s003350010196","article-title":"The olfactory receptor gene superfamily: data mining, classification, and nomenclature","volume":"11","author":"Glusman","year":"2000","journal-title":"Mamm. Genome"},{"key":"10.1016\/j.dci.2024.105149_bib10","first-page":"265","article-title":"The evolution and structure of atypical T cell receptors","volume":"vol. 57","author":"Hansen","year":"2015"},{"key":"10.1016\/j.dci.2024.105149_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1101\/gr.099416.109","article-title":"Ecological adaptation determines functional mammalian olfactory subgenomes","volume":"20","author":"Hayden","year":"2010","journal-title":"Genome Res."},{"key":"10.1016\/j.dci.2024.105149_bib12","doi-asserted-by":"crossref","first-page":"612","DOI":"10.5483\/BMBRep.2012.45.11.232","article-title":"Olfactory receptors in non-chemosensory tissues","volume":"45","author":"Kang","year":"2012","journal-title":"BMB Reports"},{"key":"10.1016\/j.dci.2024.105149_bib13","doi-asserted-by":"crossref","first-page":"2832","DOI":"10.1093\/molbev\/msv155","article-title":"Olfactory receptor subgenomes linked with broad ecological adaptations in Sauropsida","volume":"32","author":"Khan","year":"2015","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.dci.2024.105149_bib14","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1093\/molbev\/msy096","article-title":"Mega X: molecular evolutionary genetics analysis cross computing platforms","volume":"35","author":"Kumar","year":"2018","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.dci.2024.105149_bib15","doi-asserted-by":"crossref","first-page":"W293","DOI":"10.1093\/nar\/gkab301","article-title":"Interactive tree of life (iTOL) v5: an online tool for phylogenetic tree display and annotation","volume":"49","author":"Letunic","year":"2021","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dci.2024.105149_bib16","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.dci.2024.105149_bib17","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1189\/jlb.2A0714-331RR","article-title":"Class I odorant receptors, TAS1R and TAS2R taste receptors, are markers for subpopulations of circulating leukocytes","volume":"97","author":"Malki","year":"2015","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.dci.2024.105149_bib19","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1126\/science.abe7070","article-title":"The molecular assembly of the marsupial \u03b3\u03bc T cell receptor defines a third T cell lineage","volume":"371","author":"Morrissey","year":"2021","journal-title":"Science"},{"key":"10.1016\/j.dci.2024.105149_bib20","doi-asserted-by":"crossref","first-page":"1960","DOI":"10.4049\/jimmunol.2101158","article-title":"Comparison of reptilian genomes reveals deletions associated with the natural loss of \u03b3\u03b4 T cells in squamates","volume":"208","author":"Morrissey","year":"2022","journal-title":"J. Immunol."},{"key":"10.1016\/j.dci.2024.105149_bib21","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.gene.2004.09.025","article-title":"Comparative evolutionary analysis of olfactory receptor gene clusters between humans and mice","volume":"346","author":"Niimura","year":"2005","journal-title":"Gene"},{"key":"10.1016\/j.dci.2024.105149_bib22","doi-asserted-by":"crossref","first-page":"e708","DOI":"10.1371\/journal.pone.0000708","article-title":"Extensive gains and losses of olfactory receptor genes in mammalian evolution","volume":"2","author":"Niimura","year":"2007","journal-title":"PLoS One"},{"key":"10.1016\/j.dci.2024.105149_bib23","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/j.dci.2011.01.019","article-title":"A family tree of vertebrate chemokine receptors for a unified nomenclature","volume":"35","author":"Nomiyama","year":"2011","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2024.105149_bib24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1479-7364-3-1-87","article-title":"Update on the olfactory receptor (OR) gene superfamily","volume":"3","author":"Olender","year":"2008","journal-title":"Hum. Genom."},{"key":"10.1016\/j.dci.2024.105149_bib25","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/978-1-62703-377-0_2","article-title":"HORDE: comprehensive resource for olfactory receptor genomics","author":"Olender","year":"2013","journal-title":"Olfactory Receptors: Methods and Protocols"},{"key":"10.1016\/j.dci.2024.105149_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12862-020-01607-6","article-title":"A unified nomenclature for vertebrate olfactory receptors","volume":"20","author":"Olender","year":"2020","journal-title":"BMC Evol. Biol."},{"key":"10.1016\/j.dci.2024.105149_bib27","doi-asserted-by":"crossref","first-page":"9776","DOI":"10.1073\/pnas.0609106104","article-title":"A unique T cell receptor discovered in marsupials","volume":"104","author":"Parra","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.dci.2024.105149_bib28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2164-9-111","article-title":"Comparative genomic analysis and evolution of the T cell receptor loci in the opossum Monodelphis domestica","volume":"9","author":"Parra","year":"2008","journal-title":"BMC Genom."},{"key":"10.1016\/j.dci.2024.105149_bib29","doi-asserted-by":"crossref","first-page":"3205","DOI":"10.1093\/molbev\/mss128","article-title":"A model for the evolution of the mammalian t-cell receptor \u03b1\/\u03b4 and \u03bc loci based on evidence from the duckbill Platypus","volume":"29","author":"Parra","year":"2012","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.dci.2024.105149_bib30","doi-asserted-by":"crossref","first-page":"3912","DOI":"10.4049\/jimmunol.1103521","article-title":"A second TCR\u03b4 locus in Galliformes uses antibody-like V domains: insight into the evolution of TCR\u03b4 and TCR\u03bc genes in tetrapods","volume":"188","author":"Parra","year":"2012","journal-title":"J. Immunol."},{"key":"10.1016\/j.dci.2024.105149_bib31","series-title":"R: A Language and Environment for Statistical Computing","year":"2021"},{"key":"10.1016\/j.dci.2024.105149_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1074-7613(00)80237-X","article-title":"\u03b1, \u03b2, \u03b3, and \u03b4 T cell antigen receptor genes arose early in vertebrate phylogeny","volume":"6","author":"Rast","year":"1997","journal-title":"Immunity"},{"key":"10.1016\/j.dci.2024.105149_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2021.104141","article-title":"Single-cell transcriptome analysis of the B-cell repertoire reveals the usage of immunoglobulins in the gray short-tailed opossum (Monodelphis domestica)","volume":"123","author":"Schraven","year":"2021","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2024.105149_bib34","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.jgg.2023.03.006","article-title":"Parallel evolution of fish bi-modal breathing and expansion of olfactory receptor (OR) genes: toward a universal ORs nomenclature","volume":"8","author":"Silva","year":"2023","journal-title":"Journal of Genetics and Genomics"},{"key":"10.1016\/j.dci.2024.105149_bib35","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/nature10342","article-title":"The genome sequence of Atlantic cod reveals a unique immune system","volume":"477","author":"Star","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.dci.2024.105149_bib36","doi-asserted-by":"crossref","first-page":"11030","DOI":"10.1073\/pnas.0404206101","article-title":"Prospects for inferring very large phylogenies by using the neighbor-joining method","volume":"101","author":"Tamura","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.dci.2024.105149_bib37","doi-asserted-by":"crossref","first-page":"4673","DOI":"10.1093\/nar\/22.22.4673","article-title":"Clustal W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position specific gap penalties and weight matrix choice","volume":"22","author":"Thompson","year":"1994","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dci.2024.105149_bib38","doi-asserted-by":"crossref","first-page":"5246","DOI":"10.4049\/jimmunol.1101113","article-title":"Platypus TCR\u03bc provides insight into the origins and evolution of a uniquely mammalian TCR locus","volume":"187","author":"Wang","year":"2011","journal-title":"J. Immunol."},{"key":"10.1016\/j.dci.2024.105149_bib39","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1038\/nature06936","article-title":"Genome analysis of the platypus reveals unique signatures of evolution","volume":"453","author":"Warren","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.dci.2024.105149_bib40","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1038\/s41586-020-03039-0","article-title":"Platypus and echidna genomes reveal mammalian biology and evolution","volume":"592","author":"Zhou","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.dci.2024.105149_bib18","doi-asserted-by":"crossref","unstructured":"Molecular Basis for Odor Recognition. Cell 65, 175-187. https:\/\/dx.doi.org\/10.1016\/0092-8674(91)90418-x.","DOI":"10.1016\/0092-8674(91)90418-X"}],"container-title":["Developmental & Comparative Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145305X24000211?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145305X24000211?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T01:52:27Z","timestamp":1758937947000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0145305X24000211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":40,"alternative-id":["S0145305X24000211"],"URL":"https:\/\/doi.org\/10.1016\/j.dci.2024.105149","relation":{},"ISSN":["0145-305X"],"issn-type":[{"value":"0145-305X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A family of olfactory receptors uniquely expanded in marsupial and monotreme genomes are expressed by a T cell subset also unique to marsupials and monotremes","name":"articletitle","label":"Article Title"},{"value":"Developmental & Comparative Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dci.2024.105149","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"105149"}}