{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T04:11:31Z","timestamp":1793074291586,"version":"4.5.0"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental & Comparative Immunology"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.dci.2024.105225","type":"journal-article","created":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T16:51:50Z","timestamp":1720543910000},"page":"105225","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Analyses of the Mx family members in lumpfish: Molecular characterization, phylogeny, and gene expression analyses"],"prefix":"10.1016","volume":"159","author":[{"given":"Shreesha Sadashiva","family":"Rao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Skinnemoen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda K\u00e4stel Sandal","family":"Fond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gyri Teien","family":"Haugland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.dci.2024.105225_bib1","doi-asserted-by":"crossref","first-page":"21829","DOI":"10.1074\/jbc.M201641200","article-title":"The antiviral dynamin family member, MxA, tubulates lipids and localizes to the smooth endoplasmic reticulum","volume":"277","author":"Accola","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.dci.2024.105225_bib2","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1016\/j.fsi.2013.02.005","article-title":"Innate immunity of finfish: primordial conservation and function of viral RNA sensors in teleosts","volume":"35","author":"Aoki","year":"2013","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib3","doi-asserted-by":"crossref","DOI":"10.3390\/vaccines11050930","article-title":"You shall not pass: MX2 proteins are versatile viral inhibitors","volume":"11","author":"Betancor","year":"2023","journal-title":"Vaccines"},{"key":"10.1016\/j.dci.2024.105225_bib4","doi-asserted-by":"crossref","first-page":"6715","DOI":"10.4049\/jimmunol.161.12.6715","article-title":"Two families of GTPases dominate the complex cellular response to IFN-\u03b3","volume":"161","author":"Boehm","year":"1998","journal-title":"J. Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib5","doi-asserted-by":"crossref","first-page":"8036","DOI":"10.1073\/pnas.1501844112","article-title":"Mx1 and Mx2 key antiviral proteins are surprisingly lost in toothed whales","volume":"112","author":"Braun","year":"2015","journal-title":"P Natl. Acad. Sci. USA"},{"key":"10.1016\/j.dci.2024.105225_bib6","doi-asserted-by":"crossref","first-page":"7738","DOI":"10.1128\/JVI.00214-14","article-title":"Host and viral determinants of Mx2 antiretroviral activity","volume":"88","author":"Busnadiego","year":"2014","journal-title":"J. Virol."},{"key":"10.1016\/j.dci.2024.105225_bib7","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.virol.2003.08.040","article-title":"In vitro inhibition of fish rhabdoviruses by Japanese flounder, Paralichthys olivaceus Mx","volume":"317","author":"Caipang","year":"2003","journal-title":"Virol. J."},{"key":"10.1016\/j.dci.2024.105225_bib8","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.fsi.2006.09.007","article-title":"First report of invertebrate Mx: cloning, characterization and expression analysis of Mx cDNA in disk abalone (Haliotis discus discus)","volume":"23","author":"De Zoysa","year":"2007","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2020.103608","article-title":"The proinflammatory cytokines TNF-alpha and IL-6 in lumpfish (Cyclopterus lumpus L.) -identification, molecular characterization, phylogeny and gene expression analyses","volume":"105","author":"Eggest\u00f8l","year":"2020","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib10","doi-asserted-by":"crossref","first-page":"502","DOI":"10.3389\/fimmu.2020.00502","article-title":"Interleukin-1 ligands and receptors in lumpfish (Cyclopterus lumpus L.): molecular characterization, phylogeny, gene expression, and transcriptome analyses","volume":"11","author":"Eggest\u00f8l","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib11","doi-asserted-by":"crossref","first-page":"5261","DOI":"10.1038\/s41598-018-23667-x","article-title":"Transcriptome-wide mapping of signaling pathways and early immune responses in lumpfish leukocytes upon in vitro bacterial exposure","volume":"8","author":"Eggest\u00f8l","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.dci.2024.105225_bib12","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/nrg2703","article-title":"Origin and evolution of the adaptive immune system: genetic events and selective pressures","volume":"11","author":"Flajnik","year":"2010","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.dci.2024.105225_bib13","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.immuni.2011.07.012","article-title":"Structure of myxovirus resistance protein A reveals intra- and intermolecular domain interactions required for the antiviral function","volume":"35","author":"Gao","year":"2011","journal-title":"Immunity"},{"key":"10.1016\/j.dci.2024.105225_bib14","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1007\/s00438-014-0889-2","article-title":"Whole-genome duplication in teleost fishes and its evolutionary consequences","volume":"289","author":"Glasauer","year":"2014","journal-title":"Mol. Genet. Genom."},{"key":"10.1016\/j.dci.2024.105225_bib15","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.733266","article-title":"Lumpfish (Cyclopterus lumpus) is susceptible to Renibacterium salmoninarum infection and induces cell-mediated immunity in the chronic stage","volume":"12","author":"Gnanagobal","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib16","doi-asserted-by":"crossref","first-page":"9017","DOI":"10.1128\/JVI.01269-14","article-title":"Transfer of the amino-terminal nuclear envelope targeting domain of human MX2 converts MX1 into an HIV-1 resistance factor","volume":"88","author":"Goujon","year":"2014","journal-title":"Virol. J."},{"key":"10.1016\/j.dci.2024.105225_bib17","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.tim.2014.12.003","article-title":"Mx GTPases: dynamin-like antiviral machines of innate immunity","volume":"23","author":"Haller","year":"2015","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.dci.2024.105225_bib18","series-title":"Aquaculture Health Management","first-page":"319","article-title":"Application of biological control: use of cleaner fish","author":"Haugland","year":"2020"},{"key":"10.1016\/j.dci.2024.105225_bib19","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0047909","article-title":"Phagocytosis and respiratory burst activity in lumpsucker (Cyclopterus lumpus L.) leucocytes analysed by flow cytometry","volume":"7","author":"Haugland","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.dci.2024.105225_bib20","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1016\/j.fsi.2013.07.012","article-title":"Characterization of four Mx isoforms in the European eel, Anguilla anguilla","volume":"35","author":"Huang","year":"2013","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib21","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1006\/fsim.2001.0406","article-title":"Effect of poly I: C on the expression of Mx proteins and resistance against infection by infectious salmon anaemia virus in Atlantic salmon","volume":"13","author":"Jensen","year":"2002","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2022.738230","article-title":"Lack of population genetic structure of lumpfish along the Norwegian coast: a reappraisal based on EST-STRs analyses","volume":"555","author":"J\u00f3nsd\u00f3ttir","year":"2022","journal-title":"Aquaculture"},{"key":"10.1016\/j.dci.2024.105225_bib23","doi-asserted-by":"crossref","first-page":"7938","DOI":"10.1128\/JVI.78.15.7938-7944.2004","article-title":"Inhibition of infectious pancreatic necrosis virus replication by Atlantic salmon Mx1 protein","volume":"78","author":"Larsen","year":"2004","journal-title":"Virol. J."},{"key":"10.1016\/j.dci.2024.105225_bib24","doi-asserted-by":"crossref","first-page":"906","DOI":"10.3389\/fimmu.2019.00906","article-title":"Pattern recognition by melanoma differentiation-associated gene 5 (Mda5) in teleost fish: a review","volume":"10","author":"Lazarte","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib25","doi-asserted-by":"crossref","DOI":"10.1371\/annotation\/4de7ddfd-52df-4f87-8ca4-d48afe646ca8","article-title":"IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling","volume":"9","author":"Lazear","year":"2013","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.dci.2024.105225_bib26","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S0145-305X(99)00060-9","article-title":"Cloning and analysis of expression of Mx cDNA in Japanese flounder, Paralichthys olivaceus","volume":"24","author":"Lee","year":"2000","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib27","series-title":"The Evolution of the Immune System: Conservation and Diversification","author":"Malagoli","year":"2016"},{"key":"10.1016\/j.dci.2024.105225_bib28","doi-asserted-by":"crossref","first-page":"6263","DOI":"10.1128\/jvi.64.12.6263-6269.1990","article-title":"Activity of rat Mx proteins against a rhabdovirus","volume":"64","author":"Meier","year":"1990","journal-title":"J. Virol."},{"key":"10.1016\/j.dci.2024.105225_bib29","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.mib.2013.04.005","article-title":"An evolutionary perspective on the broad antiviral specificity of MxA","volume":"16","author":"Mitchell","year":"2013","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.dci.2024.105225_bib30","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.chom.2012.09.005","article-title":"Evolution-guided identification of antiviral specificity determinants in the broadly acting interferon-induced innate immunity factor MxA","volume":"12","author":"Mitchell","year":"2012","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.dci.2024.105225_bib31","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1093\/molbev\/msu300","article-title":"IQ-TREE: a fast and effective stochastic algorithm for estimating maximum-likelihood phylogenies","volume":"32","author":"Nguyen","year":"2015","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.dci.2024.105225_bib32","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.vetimm.2013.03.003","article-title":"Two Mx genes identified in European sea bass (Dicentrarchus labrax) respond differently to VNNV infection","volume":"153","author":"Novel","year":"2013","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.dci.2024.105225_bib33","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.3390\/v14071546","article-title":"Fish innate immune response to viral infection\u2014an overview of five major antiviral genes","volume":"14","author":"Ortega-Villaizan","year":"2022","journal-title":"Viruses"},{"key":"10.1016\/j.dci.2024.105225_bib34","doi-asserted-by":"crossref","first-page":"6020","DOI":"10.1074\/jbc.M113.543892","article-title":"Structural requirements for the antiviral activity of the human MxA protein against Thogoto and influenza A virus","volume":"289","author":"Patzina","year":"2014","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.dci.2024.105225_bib35","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0052142","article-title":"Protective roles of grass carp (Ctenopharyngodon idella) Mx isoforms against grass carp reovirus","volume":"7","author":"Peng","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.dci.2024.105225_bib36","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1111\/raq.12194","article-title":"Use of lumpfish for sea-lice control in salmon farming: challenges and opportunities","volume":"10","author":"Powell","year":"2018","journal-title":"Rev. Aquacult."},{"key":"10.1016\/j.dci.2024.105225_bib37","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s00438-018-1490-x","article-title":"Birth and death of Mx genes and the presence\/absence of genes regulating Mx transcription are correlated with the diversity of anti-pathogenicity in vertebrate species","volume":"294","author":"Qi","year":"2019","journal-title":"Mol. Genet. Genom."},{"key":"10.1016\/j.dci.2024.105225_bib38","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1198211","article-title":"Transcriptome-wide analyses of early immune responses in lumpfish leukocytes upon stimulation with poly(I:C)","volume":"14","author":"Rao","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib39","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2023.1252744","article-title":"Evolutionary, comparative, and functional analyses of STATs and regulation of the JAK-STAT pathway in lumpfish upon bacterial and poly(I:C) exposure","volume":"13","author":"Rao","year":"2023","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.dci.2024.105225_bib40","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.fsi.2005.01.010","article-title":"The interferon system of teleost fish","volume":"20","author":"Robertsen","year":"2006","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib41","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.dci.2018.09.004","article-title":"Analysis of the Atlantic salmon genome reveals a cluster of Mx genes that respond more strongly to IFN gamma than to type I IFN","volume":"90","author":"Robertsen","year":"2019","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib42","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S0145-305X(97)00019-0","article-title":"Molecular cloning of double-stranded RNA inducible Mx genes from Atlantic salmon (Salmo salar L.)","volume":"21","author":"Robertsen","year":"1997","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib43","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1016\/j.ijbiomac.2020.07.293","article-title":"Structure of fish Toll-like receptors (TLR) and NOD-like receptors (NLR)","volume":"161","author":"Sahoo","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.dci.2024.105225_bib44","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.compbiolchem.2017.12.011","article-title":"Interferon induced Mx protein from Indian snow trout Schizothorax richardsonii (Gray) lacks critical functional features unlike its mammalian homologues","volume":"73","author":"Saxena","year":"2018","journal-title":"Comput. Biol. Chem."},{"key":"10.1016\/j.dci.2024.105225_bib45","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1007\/s12038-021-00187-x","article-title":"Metastable biomolecular condensates of interferon-inducible antiviral Mx-family GTPases: a paradigm shift in the last three years","volume":"46","author":"Sehgal","year":"2021","journal-title":"J. Biosci."},{"key":"10.1016\/j.dci.2024.105225_bib46","first-page":"3508","article-title":"Successive losses of central immune genes characterize the Gadiformes' alternate immunity","volume":"8","author":"Solbakken","year":"2016","journal-title":"GBE"},{"key":"10.1016\/j.dci.2024.105225_bib47","first-page":"4518","article-title":"Influenza virus-susceptible mice carry Mx genes with a large deletion or a nonsense mutation","volume":"8","author":"Staeheli","year":"1988","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.dci.2024.105225_bib48","first-page":"4524","article-title":"Identification of a second interferon-regulated murine Mx gene","volume":"8","author":"Staeheli","year":"1988","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.dci.2024.105225_bib49","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1089\/jir.2006.26.650","article-title":"Interferon-induced, antiviral human MxA protein localizes to a distinct subcompartment of the smooth endoplasmic reticulum","volume":"26","author":"Stertz","year":"2006","journal-title":"J. Interferon Cytokine Res."},{"key":"10.1016\/j.dci.2024.105225_bib50","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1016\/j.fsi.2008.12.007","article-title":"Enhanced grass carp reovirus resistance of Mx-transgenic rare minnow (Gobiocypris rarus)","volume":"26","author":"Su","year":"2009","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib51","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.fsi.2010.10.020","article-title":"Construction and analysis of the immune effect of an Edwardsiella tarda DNA vaccine encoding a D15-like surface antigen","volume":"30","author":"Sun","year":"2011","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib52","doi-asserted-by":"crossref","first-page":"3022","DOI":"10.1093\/molbev\/msab120","article-title":"MEGA11: molecular evolutionary genetics analysis version 11","volume":"38","author":"Tamura","year":"2021","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.dci.2024.105225_bib53","doi-asserted-by":"crossref","first-page":"920","DOI":"10.3390\/v3060920","article-title":"Pattern recognition receptors and the innate immune response to viral infection","volume":"3","author":"Thompson","year":"2011","journal-title":"Viruses"},{"key":"10.1016\/j.dci.2024.105225_bib54","doi-asserted-by":"crossref","DOI":"10.1128\/MMBR.00011-14","article-title":"Mx proteins: antiviral gatekeepers that restrain the uninvited (vol 77, pg 551, 2013)","volume":"78","author":"Verhelst","year":"2014","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.dci.2024.105225_bib55","doi-asserted-by":"crossref","first-page":"37858","DOI":"10.1074\/jbc.M111.249037","article-title":"Stalk domain of the dynamin-like MxA GTPase protein mediates membrane binding and liposome tubulation via the unstructured L4 loop","volume":"286","author":"von der Malsburg","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.dci.2024.105225_bib56","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.fsi.2019.04.303","article-title":"Lineage\/species-specific expansion of the Mx gene family in teleosts: differential expression and modulation of nine Mx genes in rainbow trout Oncorhynchus mykiss","volume":"90","author":"Wang","year":"2019","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib57","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.fsi.2019.04.227","article-title":"Lineage\/species-specific expansion of the Mx gene family in teleosts: differential expression and modulation of nine Mx genes in vitro and in vivo in rainbow trout Oncorhynchus mykiss","volume":"91","author":"Wang","year":"2019","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib58","doi-asserted-by":"crossref","first-page":"W296","DOI":"10.1093\/nar\/gky427","article-title":"SWISS-MODEL: homology modelling of protein structures and complexes","volume":"46","author":"Waterhouse","year":"2018","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dci.2024.105225_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/B978-0-12-809633-8.21290-9","article-title":"Antiviral innate immunity: introduction","volume":"577","author":"Weber","year":"2021","journal-title":"Encycl. Virol."},{"key":"10.1016\/j.dci.2024.105225_bib60","doi-asserted-by":"crossref","DOI":"10.3390\/ijms222413397","article-title":"Toll-like receptors (TLRs), NOD-like receptors (NLRs), and RIG-I-like receptors (RLRs) in innate immunity. TLRs, NLRs, and RLRs ligands as immunotherapeutic agents for hematopoietic diseases","volume":"22","author":"Wicherska-Pawlowska","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.dci.2024.105225_bib61","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.fsi.2006.09.008","article-title":"Cloning and analysis of antiviral activity of a barramundi (Lates calcarifer) Mx gene","volume":"23","author":"Wu","year":"2007","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib62","doi-asserted-by":"crossref","first-page":"2330","DOI":"10.1016\/j.molimm.2010.05.282","article-title":"Fish virus-induced interferon exerts antiviral function through Stat1 pathway","volume":"47","author":"Yu","year":"2010","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib63","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s00251-004-0658-1","article-title":"Differential expression of two Carassius auratus Mx genes in cultured CAB cells induced by grass carp hemorrhage virus and interferon","volume":"56","author":"Zhang","year":"2004","journal-title":"Immunogenetics"},{"key":"10.1016\/j.dci.2024.105225_bib64","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.dci.2012.06.003","article-title":"Molecular regulation of interferon antiviral response in fish","volume":"38","author":"Zhang","year":"2012","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2024.105225_bib65","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1002\/j.1460-2075.1992.tb05212.x","article-title":"Mechanism of human MxA protein action: variants with changed antiviral properties","volume":"11","author":"Zurcher","year":"1992","journal-title":"EMBO J."}],"container-title":["Developmental & Comparative Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145305X24000971?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145305X24000971?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T05:15:18Z","timestamp":1728364518000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0145305X24000971"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":65,"alternative-id":["S0145305X24000971"],"URL":"https:\/\/doi.org\/10.1016\/j.dci.2024.105225","relation":{},"ISSN":["0145-305X"],"issn-type":[{"value":"0145-305X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Analyses of the Mx family members in lumpfish: Molecular characterization, phylogeny, and gene expression analyses","name":"articletitle","label":"Article Title"},{"value":"Developmental & Comparative Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dci.2024.105225","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"105225"}}