{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T13:09:25Z","timestamp":1781788165185,"version":"3.54.5"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100012900","name":"Qingdao Agricultural University","doi-asserted-by":"publisher","award":["6631114317"],"award-info":[{"award-number":["6631114317"]}],"id":[{"id":"10.13039\/100012900","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31502202"],"award-info":[{"award-number":["31502202"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Shandong Province Natural Science Foundation","doi-asserted-by":"publisher","award":["ZR2021MC172"],"award-info":[{"award-number":["ZR2021MC172"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental & Comparative Immunology"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.dci.2025.105467","type":"journal-article","created":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T17:57:34Z","timestamp":1758131854000},"page":"105467","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Characterization of Integrin \u03b21 and its effects on cell adhesion, migration and apoptosis in Sebastes schlegelii"],"prefix":"10.1016","volume":"172","author":[{"given":"Xiaohua","family":"Yuan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinqing","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haitao","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingjing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.dci.2025.105467_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1084\/jem.20220342","article-title":"Integrin \u03b21 regulates marginal zone b cell differentiation and pi3k signaling","volume":"220","author":"Andreani","year":"2023","journal-title":"J. Exp. Med."},{"issue":"9","key":"10.1016\/j.dci.2025.105467_bib2","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1093\/intimm\/dxu063","article-title":"Challenges in mucosal vaccines for the control of infectious diseases","volume":"26","author":"Azegami","year":"2014","journal-title":"Int. Immunol."},{"issue":"4","key":"10.1016\/j.dci.2025.105467_bib3","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1152\/physrev.00036.2018","article-title":"Cell adhesion by integrins","volume":"99","author":"Bachmann","year":"2019","journal-title":"Physiol. Rev."},{"issue":"1","key":"10.1016\/j.dci.2025.105467_bib4","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/s00441-009-0834-6","article-title":"Integrins","volume":"339","author":"Barczyk","year":"2010","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.dci.2025.105467_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2023.740284","article-title":"Turbot (scophthalmus maximus l.) occludin gene performs the anti-inflammatory function in the intestine via the regulations by mir-140-3p in the nf-\u03bab pathway","volume":"580","author":"Cai","year":"2024","journal-title":"Aquaculture"},{"issue":"5","key":"10.1016\/j.dci.2025.105467_bib6","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1071\/RD10351","article-title":"Identification of a \u03b21 integrin isoform with restricted tissue expression in a teleost fish","volume":"23","author":"Castillo-Brice\u00f1o","year":"2011","journal-title":"Reprod. Fertil. Dev."},{"key":"10.1016\/j.dci.2025.105467_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2024.110168","article-title":"Tgf-\u03b21-induced apoptosis in retinal endothelial cells is implicated in retinal vein occlusion","volume":"250","author":"Chen","year":"2025","journal-title":"Exp. Eye Res."},{"issue":"10","key":"10.1016\/j.dci.2025.105467_bib8","doi-asserted-by":"crossref","first-page":"3175","DOI":"10.3390\/ijms19103175","article-title":"Itgb1b-deficient rare minnows delay grass carp reovirus (gcrv) entry and attenuate gcrv-triggered apoptosis","volume":"19","author":"Chen","year":"2018","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.dci.2025.105467_bib9","doi-asserted-by":"crossref","first-page":"2520","DOI":"10.1074\/jbc.M111.254128","article-title":"Integrins regulate microtubule nucleating activity of centrosome through mitogen-activated protein kinase\/extracellular signal-regulated kinase kinase\/extracellular signal-regulated kinase (mek\/erk) signaling","volume":"287","author":"Colello","year":"2012","journal-title":"J. Biol. Chem."},{"issue":"9","key":"10.1016\/j.dci.2025.105467_bib10","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1002\/dvdy.22714","article-title":"A focal adhesion protein-based mechanochemical checkpoint regulates cleft progression during branching morphogenesis","volume":"240","author":"Daley","year":"2011","journal-title":"Dev. Dyn."},{"issue":"8","key":"10.1016\/j.dci.2025.105467_bib11","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1177\/0271678X19880161","article-title":"Integrin alpha5beta1 inhibition by atn-161 reduces neuroinflammation and is neuroprotective in ischemic stroke","volume":"40","author":"Edwards","year":"2020","journal-title":"J. Cerebr. Blood Flow Metabol."},{"issue":"10","key":"10.1016\/j.dci.2025.105467_bib12","doi-asserted-by":"crossref","first-page":"17140","DOI":"10.18632\/oncotarget.15084","article-title":"Tetraspanin 8 is a novel regulator of ilk-driven \u03b21 integrin adhesion and signaling in invasive melanoma cells","volume":"8","author":"El Kharbili","year":"2017","journal-title":"Oncotarget"},{"issue":"1","key":"10.1016\/j.dci.2025.105467_bib13","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1577\/H08-009.1","article-title":"Expression analysis of selected immune-relevant genes in channel catfish during edwardsiella ictaluri infection","volume":"21","author":"Elibol-Flemming","year":"2009","journal-title":"J. Aquat. Anim. Health"},{"issue":"1","key":"10.1016\/j.dci.2025.105467_bib14","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1080\/21505594.2018.1528841","article-title":"Fibronectin (fn) cooperated with tlr2\/tlr4 receptor to promote innate immune responses of macrophages via binding to integrin \u03b21","volume":"9","author":"Fei","year":"2018","journal-title":"Virulence"},{"issue":"1","key":"10.1016\/j.dci.2025.105467_bib15","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1007\/s10120-021-01239-9","article-title":"Integrin beta1 orchestrates the abnormal cell-matrix attachment and invasive behaviour of e-cadherin dysfunctional cells","volume":"25","author":"Figueiredo","year":"2022","journal-title":"Gastric Cancer"},{"issue":"5","key":"10.1016\/j.dci.2025.105467_bib16","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1046\/j.1471-4159.2001.00173.x","article-title":"Integrin signaling via the pi3-kinase-akt pathway increases neuronal resistance to glutamate-induced apoptosis","volume":"76","author":"Gary","year":"2001","journal-title":"J. Neurochem."},{"key":"10.1016\/j.dci.2025.105467_bib17","article-title":"Laminin receptor characterization in acute myeloid leukemia: integrin \u03b17\u03b21 defines non-leukemic stem cells with migratory potential","volume":"1\u201332","author":"G\u00f6rsch","year":"2024","journal-title":"bioRxiv"},{"issue":"6","key":"10.1016\/j.dci.2025.105467_bib18","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/S0092-8674(02)00971-6","article-title":"Integrins: bidirectional, allosteric signaling machines","volume":"110","author":"Hynes","year":"2002","journal-title":"Cell"},{"issue":"4","key":"10.1016\/j.dci.2025.105467_bib19","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.bbamem.2008.12.013","article-title":"Integrins during evolution: evolutionary trees and model organisms","volume":"1788","author":"Johnson","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"issue":"2","key":"10.1016\/j.dci.2025.105467_bib20","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1038\/s41580-022-00531-5","article-title":"Organization, dynamics and mechanoregulation of integrin-mediated cell-ecm adhesions","volume":"24","author":"Kanchanawong","year":"2023","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.dci.2025.105467_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2020.103869","article-title":"Bmintegrin \u03b21: a broadly expressed molecule modulates the innate immune response of bombyx mori","volume":"114","author":"Li","year":"2021","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2025.105467_bib22","first-page":"1","article-title":"Hgf accelerates wound healing by promoting the dedifferentiation of epidermal cells through\u03b21-integrin\/ilk pathway","author":"Li","year":"2013","journal-title":"BioMed Res. Int."},{"issue":"2","key":"10.1016\/j.dci.2025.105467_bib23","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1152\/physiolgenomics.00053.2023","article-title":"Panoptosis in vascular smooth muscle cells regulated by tnf-\u03b1\/il-1\u03b2 can be a new target for alleviating the progression of abdominal aortic aneurysm","volume":"56","author":"Li","year":"2024","journal-title":"Physiol. Genom."},{"issue":"12","key":"10.1016\/j.dci.2025.105467_bib24","doi-asserted-by":"crossref","first-page":"5988","DOI":"10.1167\/iovs.09-3591","article-title":"Integrin alpha5beta1 mediates attachment, migration, and proliferation in human retinal pigment epithelium: relevance for proliferative retinal disease","volume":"50","author":"Li","year":"2009","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.dci.2025.105467_bib25","article-title":"Genome-wide characterization of integrin (itg) gene family and their expression profiling in half-smooth tongue sole (cynoglossus semilaevis) upon vibrio anguillarum infection","volume":"47","author":"Li","year":"2023","journal-title":"Comp. Biochem. Physiol., Part D: Genomics Proteomics"},{"issue":"6","key":"10.1016\/j.dci.2025.105467_bib26","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1111\/cas.15362","article-title":"Laptm4b-35 promotes cancer cell migration via stimulating integrin beta1 recycling and focal adhesion dynamics","volume":"113","author":"Liu","year":"2022","journal-title":"Cancer Sci."},{"key":"10.1016\/j.dci.2025.105467_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2024.109918","article-title":"Hypoxia induces reversible gill remodeling in largemouth bass (micropterus salmoides) through integrins-mediated cell adhesion","volume":"154","author":"Liu","year":"2024","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2025.105467_bib28","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/s12978-015-0062-3","article-title":"Electromagnetic radiation at 900 mhz induces sperm apoptosis through bcl-2, bax and caspase-3 signaling pathways in rats","volume":"12","author":"Liu","year":"2015","journal-title":"Reprod. Health"},{"issue":"1","key":"10.1016\/j.dci.2025.105467_bib29","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.canlet.2014.05.017","article-title":"Androgen receptor enhances cell adhesion and decreases cell migration via modulating beta1-integrin-akt signaling in hepatocellular carcinoma cells","volume":"351","author":"Ma","year":"2014","journal-title":"Cancer Lett."},{"key":"10.1016\/j.dci.2025.105467_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2025.110357","article-title":"Characterization and functional analysis of integrin \u03b1v in sebastes schlegelii: implications for apoptosis, adhesion, and migration in intestinal cells","volume":"162","author":"Ma","year":"2025","journal-title":"Fish Shellfish Immunol."},{"issue":"7","key":"10.1016\/j.dci.2025.105467_bib31","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.dci.2009.02.004","article-title":"A beta integrin subunit regulates bacterial phagocytosis in medfly haemocytes","volume":"33","author":"Mamali","year":"2009","journal-title":"Dev. Comp. Immunol."},{"issue":"2","key":"10.1016\/j.dci.2025.105467_bib32","first-page":"309","article-title":"Integrin beta1 establishes liver microstructure and modulates transforming growth factor beta during liver development and regeneration","volume":"191","author":"Masuzaki","year":"2021","journal-title":"Am. J. Clin. Pathol."},{"key":"10.1016\/j.dci.2025.105467_bib33","article-title":"Hydrogen sulfide recruits macrophage migration by integrin beta1-src-fak\/pyk2-rac pathway in myocardial infarction","volume":"6","author":"Miao","year":"2016","journal-title":"Sci. Rep."},{"issue":"12","key":"10.1016\/j.dci.2025.105467_bib34","doi-asserted-by":"crossref","first-page":"8879","DOI":"10.1074\/jbc.M111.311043","article-title":"Unique disulfide bonds in epidermal growth factor (egf) domains of beta3 affect structure and function of alphaiibbeta3 and alphavbeta3 integrins in different manner","volume":"287","author":"Mor-Cohen","year":"2012","journal-title":"J. Biol. Chem."},{"issue":"5929","key":"10.1016\/j.dci.2025.105467_bib35","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1126\/science.1163865","article-title":"The tail of integrins, talin, and kindlins","volume":"325","author":"Moser","year":"2009","journal-title":"science"},{"key":"10.1016\/j.dci.2025.105467_bib36","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/1471-2121-7-24","article-title":"Identification of multiple integrin beta1 homologs in zebrafish (danio rerio)","volume":"7","author":"Mould","year":"2006","journal-title":"BMC Cell Biol."},{"issue":"3","key":"10.1016\/j.dci.2025.105467_bib37","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1111\/acel.12193","article-title":"A dual role for integrin-linked kinase and beta1-integrin in modulating cardiac aging","volume":"13","author":"Nishimura","year":"2014","journal-title":"Aging Cell"},{"issue":"5","key":"10.1016\/j.dci.2025.105467_bib38","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1242\/jcs.197459","article-title":"Kon-tiki enhances ps2 integrin adhesion and localizes its ligand, thrombospondin, in the myotendinous junction","volume":"130","author":"Perez-Moreno","year":"2017","journal-title":"J. Cell Sci."},{"issue":"5","key":"10.1016\/j.dci.2025.105467_bib39","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.ceb.2012.06.003","article-title":"Ilk: a pseudokinase in the center stage of cell-matrix adhesion and signaling","volume":"24","author":"Qin","year":"2012","journal-title":"Curr. Opin. Cell Biol."},{"issue":"5","key":"10.1016\/j.dci.2025.105467_bib40","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.devcel.2019.03.023","article-title":"Rap1b promotes notch-signal-mediated hematopoietic stem cell development by enhancing integrin-mediated cell adhesion","volume":"49","author":"Rho","year":"2019","journal-title":"Dev. Cell"},{"issue":"2","key":"10.1016\/j.dci.2025.105467_bib41","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1002\/path.2577","article-title":"Beta1 integrin\/fak\/erk signalling pathway is essential for human fetal islet cell differentiation and survival","volume":"219","author":"Saleem","year":"2009","journal-title":"J. Pathol."},{"issue":"20","key":"10.1016\/j.dci.2025.105467_bib42","doi-asserted-by":"crossref","first-page":"3658","DOI":"10.1091\/mbc.E15-05-0274","article-title":"The interaction of galpha13 with integrin beta1 mediates cell migration by dynamic regulation of rhoa","volume":"26","author":"Shen","year":"2015","journal-title":"Mol. Biol. Cell"},{"issue":"8","key":"10.1016\/j.dci.2025.105467_bib43","doi-asserted-by":"crossref","DOI":"10.1002\/jcp.31298","article-title":"Gpr124 promotes trophoblast proliferation, migration, and invasion and inhibits trophoblast cell apoptosis and inflammation via jnk and p38 mapk pathways","volume":"239","author":"Shen","year":"2024","journal-title":"J. Cell. Physiol."},{"issue":"6","key":"10.1016\/j.dci.2025.105467_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2024.110129","article-title":"Acetyl-npky of integrin-\u03b21 binds kindlin2 to control endothelial cell proliferation and junctional integrity","volume":"27","author":"Sidib\u00e9","year":"2024","journal-title":"iScience"},{"issue":"1","key":"10.1016\/j.dci.2025.105467_bib45","doi-asserted-by":"crossref","first-page":"302","DOI":"10.3892\/or.2014.3168","article-title":"\u03921 integrin modulates tumor growth and apoptosis of human colorectal cancer","volume":"32","author":"Song","year":"2014","journal-title":"Oncol. Rep."},{"key":"10.1016\/j.dci.2025.105467_bib46","doi-asserted-by":"crossref","first-page":"3862","DOI":"10.1038\/ncomms4862","article-title":"Knockdown and knockout of beta1-integrin in hepatocytes impairs liver regeneration through inhibition of growth factor signalling","volume":"5","author":"Speicher","year":"2014","journal-title":"Nat. Commun."},{"issue":"11","key":"10.1016\/j.dci.2025.105467_bib47","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1016\/j.str.2006.10.001","article-title":"Complement and the multifaceted functions of vwa and integrin i domains","volume":"14","author":"Springer","year":"2006","journal-title":"Structure"},{"issue":"5642","key":"10.1016\/j.dci.2025.105467_bib48","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1126\/science.1086652","article-title":"Talin binding to integrin beta tails: a final common step in integrin activation","volume":"302","author":"Tadokoro","year":"2003","journal-title":"Science"},{"issue":"5","key":"10.1016\/j.dci.2025.105467_bib49","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1186\/gb-2007-8-5-215","article-title":"The integrins","volume":"8","author":"Takada","year":"2007","journal-title":"Genome Biol."},{"key":"10.1016\/j.dci.2025.105467_bib50","doi-asserted-by":"crossref","first-page":"738","DOI":"10.3389\/fimmu.2020.00738","article-title":"Phagocytic integrins: activation and signaling","volume":"11","author":"Torres-Gomez","year":"2020","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.dci.2025.105467_bib51","doi-asserted-by":"crossref","first-page":"4465","DOI":"10.1038\/s41467-018-06906-7","article-title":"Non-catalytic signaling by pseudokinase ilk for regulating cell adhesion","volume":"9","author":"Vaynberg","year":"2018","journal-title":"Nat. Commun."},{"issue":"4","key":"10.1016\/j.dci.2025.105467_bib52","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1007\/s10753-024-01984-w","article-title":"Phillygenin inhibits tgf-beta1-induced hepatic stellate cell activation and inflammation: regulation of the bax\/bcl-2 and wnt\/beta-catenin pathways","volume":"47","author":"Wang","year":"2024","journal-title":"Inflammation"},{"issue":"11","key":"10.1016\/j.dci.2025.105467_bib53","doi-asserted-by":"crossref","first-page":"2679","DOI":"10.1016\/j.biocel.2013.09.006","article-title":"Marveld1 regulates integrin \u03b21-mediated cell adhesion and actin organization via inhibiting its pre-mrna processing","volume":"45","author":"Wang","year":"2013","journal-title":"Int. J. Biochem. Cell Biol."},{"issue":"1","key":"10.1016\/j.dci.2025.105467_bib54","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.cell.2006.10.048","article-title":"Structural basis of integrin activation by talin","volume":"128","author":"Wegener","year":"2007","journal-title":"Cell"},{"issue":"9","key":"10.1016\/j.dci.2025.105467_bib55","first-page":"1403","article-title":"Rgd inhibition of itgb1 ameliorates laminin-alpha2-deficient zebrafish fibre pathology","volume":"28","author":"Wood","year":"2019","journal-title":"Hum. Mol. Genet."},{"issue":"4","key":"10.1016\/j.dci.2025.105467_bib56","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.3892\/mmr.2014.1937","article-title":"Wnt3a activates \u03b21-integrin and regulates migration and adhesion of vascular smooth muscle cells","volume":"9","author":"Wu","year":"2014","journal-title":"Mol. Med. Rep."},{"issue":"1","key":"10.1016\/j.dci.2025.105467_bib57","doi-asserted-by":"crossref","DOI":"10.1042\/BSR20180992","article-title":"Apoptosis and apoptotic body: disease message and therapeutic target potentials","volume":"39","author":"Xu","year":"2019","journal-title":"Biosci. Rep."},{"key":"10.1016\/j.dci.2025.105467_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2024.109993","article-title":"Establishment and characterization of ssi cell line from sebastes schlegelii intestine for investigating the immune response to pathogenic bacteria","volume":"154","author":"Xue","year":"2024","journal-title":"Fish Shellfish Immunol."},{"issue":"10","key":"10.1016\/j.dci.2025.105467_bib59","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.3390\/biology10101015","article-title":"Identification of antimicrobial peptide genes in Black rockfish sebastes schlegelii and their responsive mechanisms to edwardsiella tarda infection","volume":"10","author":"Zhang","year":"2021","journal-title":"Biology"},{"issue":"12","key":"10.1016\/j.dci.2025.105467_bib60","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.202200784","article-title":"Diallyl trisulfide, a major bioactive constituent of garlic, promotes colonic mucosal healing in ulcerativecolitis through accelerating focal adhesion assembly and consequent epithelial cell migration via the rab21-integrin beta1-fak pathway","volume":"67","author":"Zhang","year":"2023","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.dci.2025.105467_bib61","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2022.108473","article-title":"Integrin\u03b21\/fak\/erk signalling pathway is essential for chinese mitten crab eriocheir sinensis hemocyte survival","volume":"132","author":"Zhao","year":"2023","journal-title":"Fish Shellfish Immunol."},{"issue":"13","key":"10.1016\/j.dci.2025.105467_bib62","doi-asserted-by":"crossref","first-page":"1840","DOI":"10.1182\/blood-2016-07-729400","article-title":"The integrin psi domain has an endogenous thiol isomerase function and is a novel target for antiplatelet therapy","volume":"129","author":"Zhu","year":"2017","journal-title":"Blood"}],"container-title":["Developmental & Comparative Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145305X25001569?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145305X25001569?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T13:05:40Z","timestamp":1763643940000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0145305X25001569"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":62,"alternative-id":["S0145305X25001569"],"URL":"https:\/\/doi.org\/10.1016\/j.dci.2025.105467","relation":{},"ISSN":["0145-305X"],"issn-type":[{"value":"0145-305X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterization of Integrin \u03b21 and its effects on cell adhesion, migration and apoptosis in Sebastes schlegelii","name":"articletitle","label":"Article Title"},{"value":"Developmental & Comparative Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dci.2025.105467","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"105467"}}