{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T17:07:40Z","timestamp":1779210460045,"version":"3.51.4"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental & Comparative Immunology"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.dci.2026.105612","type":"journal-article","created":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T06:52:09Z","timestamp":1776840729000},"page":"105612","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Divergent disulfide bond architecture defines two IgY subclasses in snakes"],"prefix":"10.1016","volume":"179","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9263-7663","authenticated-orcid":false,"given":"Francisco","family":"Gambon Deza","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.dci.2026.105612_bib1","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1093\/bioinformatics\/btp163","article-title":"Biopython: freely available python tools for computational molecular biology and bioinformatics","volume":"25","author":"Cock","year":"2009","journal-title":"Bioinformatics"},{"issue":"1","key":"10.1016\/j.dci.2026.105612_bib2","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/nrg2703","article-title":"Origin and evolution of the adaptive immune system: genetic events and selective pressures","volume":"11","author":"Flajnik","year":"2010","journal-title":"Nat. Rev. Genet."},{"issue":"1","key":"10.1016\/j.dci.2026.105612_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.dci.2012.03.001","article-title":"Snakes antibodies","volume":"38","author":"Gamb\u00f3n-Deza","year":"2012","journal-title":"Dev. Comp. Immunol."},{"issue":"4154","key":"10.1016\/j.dci.2026.105612_bib4","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1126\/science.185.4154.862","article-title":"Amino acid difference formula to help explain protein evolution","volume":"185","author":"Grantham","year":"1974","journal-title":"Science"},{"issue":"7825","key":"10.1016\/j.dci.2026.105612_bib5","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/s41586-020-2649-2","article-title":"Array programming with NumPy","volume":"585","author":"Harris","year":"2020","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.dci.2026.105612_bib6","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1093\/molbev\/msw046","article-title":"ETE 3: reconstruction, analysis, and visualization of phylogenomic data","volume":"33","author":"Huerta-Cepas","year":"2016","journal-title":"Mol. Biol. Evol."},{"issue":"3","key":"10.1016\/j.dci.2026.105612_bib7","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1109\/MCSE.2007.55","article-title":"Matplotlib: a 2D graphics environment","volume":"9","author":"Hunter","year":"2007","journal-title":"Comput. Sci. Eng."},{"issue":"7873","key":"10.1016\/j.dci.2026.105612_bib8","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1038\/s41586-021-03819-2","article-title":"Highly accurate protein structure prediction with AlphaFold","volume":"596","author":"Jumper","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.dci.2026.105612_bib9","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1079\/WPS200422","article-title":"Chicken IgY: utilizing the evolutionary advantage","volume":"60","author":"Karlsson","year":"2004","journal-title":"Worlds Poult. Sci. J."},{"issue":"4","key":"10.1016\/j.dci.2026.105612_bib10","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1093\/molbev\/mst010","article-title":"MAFFT multiple sequence alignment software version 7: improvements in performance and usability","volume":"30","author":"Katoh","year":"2013","journal-title":"Mol. Biol. Evol."},{"issue":"5494","key":"10.1016\/j.dci.2026.105612_bib11","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1126\/science.290.5494.1151","article-title":"The evolutionary fate and consequences of duplicate genes","volume":"290","author":"Lynch","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.dci.2026.105612_bib12","series-title":"Proceedings of the 9th Python in Science Conference (SciPy 2010)","doi-asserted-by":"crossref","first-page":"56","DOI":"10.25080\/Majora-92bf1922-00a","article-title":"Data structures for statistical computing in python","author":"McKinney","year":"2010"},{"issue":"5","key":"10.1016\/j.dci.2026.105612_bib13","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1093\/molbev\/msaa015","article-title":"IQ-TREE 2: new models and efficient methods for phylogenetic inference in the genomic era","volume":"37","author":"Minh","year":"2020","journal-title":"Mol. Biol. Evol."},{"issue":"5","key":"10.1016\/j.dci.2026.105612_bib14","first-page":"418","article-title":"Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions","volume":"3","author":"Nei","year":"1986","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.dci.2026.105612_bib15","series-title":"The Immunoglobulins: Structure and Function","author":"Nezlin","year":"1998"},{"key":"10.1016\/j.dci.2026.105612_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2020.103868","article-title":"Insights into the evolution of IG genes in amphibians and reptiles","volume":"114","author":"Olivieri","year":"2021","journal-title":"Dev. Comp. Immunol."},{"issue":"8","key":"10.1016\/j.dci.2026.105612_bib17","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1093\/bioinformatics\/btu829","article-title":"3Dmol.js: molecular visualization with WebGL","volume":"31","author":"Rego","year":"2015","journal-title":"Bioinformatics"},{"key":"10.1016\/j.dci.2026.105612_bib18","doi-asserted-by":"crossref","first-page":"W609","DOI":"10.1093\/nar\/gkl315","article-title":"PAL2NAL: robust conversion of protein sequence alignments into the corresponding codon alignments","volume":"34","author":"Suyama","year":"2006","journal-title":"Nucleic Acids Res."},{"issue":"8","key":"10.1016\/j.dci.2026.105612_bib19","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/0167-5699(95)80008-5","article-title":"IgY: clues to the origins of modern antibodies","volume":"16","author":"Warr","year":"1995","journal-title":"Immunol. Today"},{"issue":"4","key":"10.1016\/j.dci.2026.105612_bib20","doi-asserted-by":"crossref","first-page":"2144","DOI":"10.1111\/brv.12325","article-title":"IgY: a key isotype in antibody evolution","volume":"92","author":"Zhang","year":"2017","journal-title":"Biol. Rev."}],"container-title":["Developmental & Comparative Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145305X26000686?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145305X26000686?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T16:25:40Z","timestamp":1779207940000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0145305X26000686"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":20,"alternative-id":["S0145305X26000686"],"URL":"https:\/\/doi.org\/10.1016\/j.dci.2026.105612","relation":{},"ISSN":["0145-305X"],"issn-type":[{"value":"0145-305X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Divergent disulfide bond architecture defines two IgY subclasses in snakes","name":"articletitle","label":"Article Title"},{"value":"Developmental & Comparative Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dci.2026.105612","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"105612"}}