{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T17:07:57Z","timestamp":1779210477250,"version":"3.51.4"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental &amp; Comparative Immunology"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.dci.2026.105622","type":"journal-article","created":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T15:27:04Z","timestamp":1778167624000},"page":"105622","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Identification and characterization of Cathepsins gene family from obscure puffer Takifugu obscurus and their expression pattern in response to diverse pathogens infection"],"prefix":"10.1016","volume":"179","author":[{"given":"Shan","family":"Zhou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nan","family":"Cui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liwen","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinrui","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junqie","family":"Qin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1124-791X","authenticated-orcid":false,"given":"Zhe","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5853-1945","authenticated-orcid":false,"given":"Xiaorui","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.dci.2026.105622_bib1","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.biochi.2023.09.018","article-title":"Cathepsin C role in inflammatory gastroenterological, renal, rheumatic, and pulmonary disorders","volume":"216","author":"Aghdassi","year":"2024","journal-title":"Biochimie"},{"key":"10.1016\/j.dci.2026.105622_bib2","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.cbpb.2008.07.001","article-title":"Molecular cloning, tissue distribution and enzymatic characterization of cathepsin X from olive flounder (Paralichthys olivaceus)","volume":"151","author":"Ahn","year":"2008","journal-title":"Comp. Biochem. Physiol. B Biochem. Mol. Biol."},{"key":"10.1016\/j.dci.2026.105622_bib3","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.955407","article-title":"Spatial localization of cathepsins: implications in immune activation and resolution during infections","volume":"13","author":"Anes","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.dci.2026.105622_bib4","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.yexcr.2017.11.015","article-title":"Cathepsin B links oxidative stress to the activation of NLRP3 inflammasome","volume":"362","author":"Bai","year":"2018","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.dci.2026.105622_bib5","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s00251-020-01196-0","article-title":"Anatomy of teleost fish immune structures and organs","volume":"73","author":"Bj\u00f8rgen","year":"2021","journal-title":"Immunogenetics"},{"key":"10.1016\/j.dci.2026.105622_bib6","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1016\/j.fsi.2011.09.012","article-title":"Identification and expressional analysis of two cathepsins from half-smooth tongue sole (Cynoglossus semilaevis)","volume":"31","author":"Chen","year":"2011","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105622_bib7","article-title":"Cathepsin C in health and disease: from structural insights to therapeutic prospects","volume":"22","author":"Chitsamankhun","year":"2024","journal-title":"Journal of Ttranslational Medicine"},{"key":"10.1016\/j.dci.2026.105622_bib8","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1096\/fj.01-0736fje","article-title":"Cathepsin D produces antimicrobial peptide parasin I from histone H2A in the skin mucosa of fish","volume":"16","author":"Cho","year":"2002","journal-title":"FASEB J."},{"key":"10.1016\/j.dci.2026.105622_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2024.110032","article-title":"Identification and characterization of 16 tripartite motif-containing proteins from Takifugu obscurus","volume":"156","author":"Cui","year":"2025","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105622_bib10","doi-asserted-by":"crossref","first-page":"433","DOI":"10.3389\/fcell.2020.00433","article-title":"Cathepsin K: the action in and beyond bone","volume":"8","author":"Dai","year":"2020","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.dci.2026.105622_bib11","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1080\/15548627.2020.1752497","article-title":"Autophagy triggers CTSD (cathepsin D) maturation and localization inside cells to promote apoptosis","volume":"17","author":"Di","year":"2021","journal-title":"Autophagy"},{"key":"10.1016\/j.dci.2026.105622_bib12","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.fsi.2022.07.078","article-title":"Cathepsin C (CTSC) contributes to the antibacterial immunity in golden pompano (Trachinotus ovatus)","volume":"128","author":"Diao","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105622_bib13","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.fsi.2015.11.030","article-title":"Expression profile analysis of two cathepsin S in channel catfish (Ictalurus punctatus) mucosal tissues following bacterial challenge","volume":"48","author":"Dong","year":"2016","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105622_bib14","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1111\/jwas.12781","article-title":"The char of migration inhibitory factor and Cathepsin B from Asian swamp eel (Monopterus albus) and their response to challenge with Aeromonas hydrophila","volume":"52","author":"Du","year":"2021","journal-title":"J. World Aquacult. Soc."},{"key":"10.1016\/j.dci.2026.105622_bib15","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s10695-025-01587-8","article-title":"Antioxidants, immunotoxicological, and histopathological impacts of polypropylene microplastics emitted from paper cups on Clarias gariepinus and the ameliorating role of Spirulina and recovery","volume":"51","author":"Eid","year":"2025","journal-title":"Fish Physiol. Biochem."},{"key":"10.1016\/j.dci.2026.105622_bib16","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.fsi.2022.08.025","article-title":"Characteristics of cathepsin members and expression responses to poly I:C challenge in Pacific cod (Gadus macrocephalus)","volume":"128","author":"Guan","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105622_bib17","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1007\/s12031-018-1110-6","article-title":"Lysosomal cathepsin protease gene expression profiles in the human brain during normal development","volume":"65","author":"Hsu","year":"2018","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.dci.2026.105622_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetimm.2021.110200","article-title":"In silico characterization and expression analysis of eight C-type lectins in obscure puffer Takifugu obscurus","volume":"234","author":"Huang","year":"2021","journal-title":"Vet. Immunol. Immunopathol."},{"key":"10.1016\/j.dci.2026.105622_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40851-022-00200-7","article-title":"Structural and immunohistochemical analysis of the cellular compositions of the liver of molly fish (Poecilia sphenops), focusing on its immune role","volume":"9","author":"Hussein","year":"2023","journal-title":"Zool. Lett."},{"key":"10.1016\/j.dci.2026.105622_bib20","doi-asserted-by":"crossref","first-page":"5133","DOI":"10.1038\/s41467-020-18935-2","article-title":"Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling","volume":"11","author":"Ketterer","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.dci.2026.105622_bib21","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.dci.2017.06.004","article-title":"The first report of cathepsin A gene in a teleost (rock bream, Oplegnathus fasciatus): an investigation of immune functions upon infection with several pathogens","volume":"76","author":"Kim","year":"2017","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2026.105622_bib22","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.yexcr.2004.12.006","article-title":"Carboxypeptidases cathepsins X and B display distinct protein profile in human cells and tissues","volume":"306","author":"Kos","year":"2005","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.dci.2026.105622_bib23","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.fsi.2015.10.028","article-title":"Identification and mucosal expression analysis of cathepsin B in channel catfish (Ictalurus punctatus) following bacterial challenge","volume":"47","author":"Li","year":"2015","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105622_bib24","article-title":"Cathepsin W restrains peripheral regulatory T cells for mucosal immune quiescence","volume":"9","author":"Li","year":"2023","journal-title":"Sci. Adv."},{"key":"10.1016\/j.dci.2026.105622_bib25","article-title":"First insight of the genome-wide association study and genomic prediction into enteritis disease (Vibrio harveyi) resistance trait in the lined seahorse (Hippocampus erectus)","volume":"15","author":"Li","year":"2024","journal-title":"Front. Immunol."},{"key":"10.1016\/j.dci.2026.105622_bib26","doi-asserted-by":"crossref","DOI":"10.3390\/md20080504","article-title":"Genome-wide identification, evolutionary analysis, and expression patterns of cathepsin superfamily in Black Rockfish (Sebastes schlegelii) following Aeromonas salmonicida Infection","volume":"20","author":"Li","year":"2022","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.dci.2026.105622_bib27","doi-asserted-by":"crossref","first-page":"837","DOI":"10.3390\/pharmaceutics13060837","article-title":"Cathepsin D-managing the delicate balance","volume":"13","author":"Mijanovic","year":"2021","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.dci.2026.105622_bib28","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.fsi.2019.04.304","article-title":"Comparative transcriptomic analysis reveals the gene expression profiles in the liver and spleen of Japanese pufferfish (Takifugu rubripes) in response to Vibrio harveyi infection","volume":"90","author":"Peng","year":"2019","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105622_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2018.e00673","article-title":"Human brain gene expression profiles of the cathepsin V and cathepsin L cysteine proteases, with the PC1\/3 and PC2 serine proteases, involved in neuropeptide production","volume":"4","author":"Podvin","year":"2018","journal-title":"Heliyon"},{"key":"10.1016\/j.dci.2026.105622_bib54","first-page":"71","article-title":"An improvement of the 2^(-delta delta CT) method for quantitative real-time polymerase chain reaction data analysis","volume":"3","author":"Rao","year":"2013","journal-title":"Biostat Bioinforma Biomath"},{"key":"10.1016\/j.dci.2026.105622_bib30","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/j.jhep.2021.06.031","article-title":"The multifaceted role of cathepsins in liver disease","volume":"75","author":"Ruiz-Bl\u00e1zquez","year":"2021","journal-title":"J. Hepatol."},{"key":"10.1016\/j.dci.2026.105622_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2025.110652","article-title":"Transcriptome to reveal the immunological defenses in mandarin fish (Siniperca chuatsi) skin with LPS and poly (I:C) infection","volume":"166","author":"Shen","year":"2025","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105622_bib32","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.fsi.2016.02.029","article-title":"Immunity decreases, antioxidant system damages and tight junction changes in the intestine of grass carp (Ctenopharyngodon idella) during folic acid deficiency: regulation of NF-\u03baB, Nrf2 and MLCK mRNA levels","volume":"51","author":"Shi","year":"2016","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105622_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2024.110035","article-title":"A preliminary investigation on the protective effects of \u03b2-glucan and mannan induced trained immunity in pufferfish Takifugu obscurus","volume":"156","author":"Song","year":"2025","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105622_bib34","doi-asserted-by":"crossref","DOI":"10.3390\/ijms242115613","article-title":"The role of cysteine protease cathepsins B, H, C, and X\/Z in neurodegenerative diseases and cancer","volume":"24","author":"Stoka","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.dci.2026.105622_bib35","doi-asserted-by":"crossref","first-page":"26","DOI":"10.4103\/1673-5374.286948","article-title":"Cathepsins in neuronal plasticity","volume":"16","author":"Tran","year":"2021","journal-title":"Neural Regen. Res."},{"key":"10.1016\/j.dci.2026.105622_bib36","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.bbapap.2011.10.002","article-title":"Cysteine cathepsins: from structure, function and regulation to new frontiers","volume":"1824","author":"Turk","year":"2012","journal-title":"Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics"},{"key":"10.1016\/j.dci.2026.105622_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellsig.2022.110531","article-title":"Cathepsins in the extracellular space: focusing on non-lysosomal proteolytic functions with clinical implications","volume":"103","author":"Wang","year":"2023","journal-title":"Cell. Signal."},{"key":"10.1016\/j.dci.2026.105622_bib38","first-page":"198","article-title":"Transcriptome analysis of the kidney of obscure puffer","volume":"39","author":"Wang","year":"2022","journal-title":"Takifugu obscurus, challenged with poly(i:c). Zoological Science"},{"key":"10.1016\/j.dci.2026.105622_bib39","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.fsi.2015.09.047","article-title":"Mucosal expression signatures of two Cathepsin L in channel catfish (Ictalurus punctatus) following bacterial challenge","volume":"47","author":"Wang","year":"2015","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105622_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2024.105278","article-title":"The essential function of cathepsin X of the orange-spotted grouper, Epinephelus coioides during SGIV infection","volume":"162","author":"Wang","year":"2025","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2026.105622_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2023.108594","article-title":"Cathepsin H and cathepsin B of Cynoglossus semilaevis are involved in anti-bacterial immunity against Edwardsiella tarda","volume":"134","author":"Wang","year":"2023","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105622_bib42","doi-asserted-by":"crossref","first-page":"W296","DOI":"10.1093\/nar\/gky427","article-title":"SWISS-MODEL: homology modelling of protein structures and complexes","volume":"46","author":"Waterhouse","year":"2018","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dci.2026.105622_bib43","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/j.dci.2005.10.014","article-title":"Granzyme-like sequences in bony fish shed light on the emergence of hematopoietic serine proteases during vertebrate evolution","volume":"30","author":"Wernersson","year":"2006","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2026.105622_bib44","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.fsi.2010.12.022","article-title":"Molecular characterization and expression analysis of Cathepsin B and L cysteine proteases from rock bream (Oplegnathus fasciatus)","volume":"30","author":"Whang","year":"2011","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105622_bib45","article-title":"Fish gut-liver immunity during homeostasis or inflammation revealed by integrative transcriptome and proteome studies","volume":"6","author":"Wu","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.dci.2026.105622_bib46","doi-asserted-by":"crossref","first-page":"W587","DOI":"10.1093\/nar\/gkad359","article-title":"Tree Visualization by one table (tvBOT): a web application for visualizing, modifying and annotating phylogenetic trees","volume":"51","author":"Xie","year":"2023","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dci.2026.105622_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2023.106783","article-title":"Whole genome identification of olive flounder (Paralichthys olivaceus) cathepsin genes: provides insights into its regulation on biotic and abiotic stresses response","volume":"266","author":"Xie","year":"2024","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.dci.2026.105622_bib48","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.theriogenology.2020.12.023","article-title":"Molecular characterization and expression profiles of six genes involved in vitellogenic deposition and hydrolysis of Chinese sturgeon (Acipenser sinensis) suggesting their transcriptional regulation on ovarian development","volume":"162","author":"Yao","year":"2021","journal-title":"Theriogenology"},{"key":"10.1016\/j.dci.2026.105622_bib49","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.819029","article-title":"PU.1 regulates cathepsin S expression in large yellow croaker (Larimichthys crocea) macrophages","volume":"12","author":"Zhang","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.dci.2026.105622_bib50","first-page":"165","article-title":"The multifaceted roles of cathepsins in immune and inflammatory responses: implications for cancer therapy","volume":"12","author":"Zhao","year":"2024","journal-title":"autoimmune diseases, and infectious diseases. Biomarker Research"},{"key":"10.1016\/j.dci.2026.105622_bib51","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.7150\/ijbs.11751","article-title":"Evolutionary history of cathepsin L (L-like) family genes in vertebrates","volume":"11","author":"Zhou","year":"2015","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.dci.2026.105622_bib52","first-page":"38","article-title":"Research progress in the mechanisms and functions of gene loss in genome evolution","volume":"41","author":"Zhou","year":"2025","journal-title":"Biotechnol. Bull."},{"key":"10.1016\/j.dci.2026.105622_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2025.742918","article-title":"Single-cell RNA sequencing reveals the immune cell landscape of head kidney in the perciform fish (Micropterus salmoides)","volume":"610","author":"Zhou","year":"2026","journal-title":"Aquaculture"}],"container-title":["Developmental &amp; Comparative Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145305X26000789?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145305X26000789?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T16:26:24Z","timestamp":1779207984000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0145305X26000789"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":54,"alternative-id":["S0145305X26000789"],"URL":"https:\/\/doi.org\/10.1016\/j.dci.2026.105622","relation":{},"ISSN":["0145-305X"],"issn-type":[{"value":"0145-305X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification and characterization of Cathepsins gene family from obscure puffer Takifugu obscurus and their expression pattern in response to diverse pathogens infection","name":"articletitle","label":"Article Title"},{"value":"Developmental & Comparative Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dci.2026.105622","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"105622"}}