{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T15:30:45Z","timestamp":1786116645215,"version":"build-2736575974"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100011785","name":"Guangxi Science and Technology Department","doi-asserted-by":"publisher","award":["GuiKe-LT2600640018"],"award-info":[{"award-number":["GuiKe-LT2600640018"]}],"id":[{"id":"10.13039\/501100011785","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32373169"],"award-info":[{"award-number":["32373169"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["41976123"],"award-info":[{"award-number":["41976123"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental & Comparative Immunology"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.dci.2026.105680","type":"journal-article","created":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T07:05:15Z","timestamp":1783494315000},"page":"105680","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Identification of genes directly regulated by LvBlimp1 in shrimp macrophage-like phagocytes"],"prefix":"10.1016","volume":"181","author":[{"given":"Youngli","family":"He","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huimin","family":"Ouyang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaming","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenyong","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaohui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuo","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuli","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongzhen","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingyun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6059-6956","authenticated-orcid":false,"given":"Fan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.dci.2026.105680_bib1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/75556","article-title":"Gene ontology: tool for the unification of biology. The gene ontology consortium","volume":"25","author":"Ashburner","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1016\/j.dci.2026.105680_bib2","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/s41385-021-00480-w","article-title":"The impact of the lung environment on macrophage development, activation and function: diversity in the face of adversity","volume":"15","author":"Bain","year":"2022","journal-title":"Mucosal Immunol."},{"key":"10.1016\/j.dci.2026.105680_bib3","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-12171-3","article-title":"Differential regulation of effector and regulatory T cell function by Blimp1","volume":"7","author":"Bankoti","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.dci.2026.105680_bib4","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/j.immuni.2023.04.001","article-title":"Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity","volume":"56","author":"Bharadwaj","year":"2023","journal-title":"Immunity"},{"key":"10.1016\/j.dci.2026.105680_bib5","doi-asserted-by":"crossref","first-page":"4516","DOI":"10.1038\/sj.onc.1207593","article-title":"Aurora B-TACC1 protein complex in cytokinesis","volume":"23","author":"Delaval","year":"2004","journal-title":"Oncogene"},{"key":"10.1016\/j.dci.2026.105680_bib6","doi-asserted-by":"crossref","first-page":"5336","DOI":"10.1093\/nar\/gkq268","article-title":"An extended set of PRDM1\/BLIMP1 target genes links binding motif type to dynamic repression","volume":"38","author":"Doody","year":"2010","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dci.2026.105680_bib7","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1002\/cm.70000","article-title":"Perspective: examining MAP1B structure with an evolutionary perspective","volume":"83","author":"Fischer","year":"2026","journal-title":"Cytoskeleton"},{"key":"10.1016\/j.dci.2026.105680_bib8","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s12929-017-0354-8","article-title":"New insights into Blimp-1 in T lymphocytes: a divergent regulator of cell destiny and effector function","volume":"24","author":"Fu","year":"2017","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.dci.2026.105680_bib9","doi-asserted-by":"crossref","first-page":"14352","DOI":"10.1073\/pnas.97.26.14352","article-title":"The TACC domain identifies a family of centrosomal proteins that can interact with microtubules","volume":"97","author":"Gergely","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.dci.2026.105680_bib10","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0896-6273(00)81169-1","article-title":"Drosophila Futsch\/22C10 is a MAP1B-like protein required for dendritic and axonal development","volume":"26","author":"Hummel","year":"2000","journal-title":"Neuron"},{"key":"10.1016\/j.dci.2026.105680_bib11","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.3390\/v17111463","article-title":"Combating white spot syndrome virus (WSSV) in global shrimp farming: unraveling its biology, pathology, and control strategies","volume":"17","author":"Iftehimul","year":"2025","journal-title":"Viruses"},{"key":"10.1016\/j.dci.2026.105680_bib13","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/nri.2017.28","article-title":"Monocyte differentiation and antigen-presenting functions","volume":"17","author":"Jakubzick","year":"2017","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.dci.2026.105680_bib14","doi-asserted-by":"crossref","first-page":"3620","DOI":"10.3390\/molecules30173620","article-title":"Managing Vibrio parahaemolyticus and Vibrio alginolyticus infections in the whiteleg shrimp (Penaeus vannamei): a systematic review","volume":"30","author":"Jara-Medina","year":"2025","journal-title":"Molecules"},{"key":"10.1016\/j.dci.2026.105680_bib15","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/j.yexcr.2008.11.015","article-title":"Blimp1: a conserved transcriptional repressor critical for differentiation of many tissues","volume":"315","author":"John","year":"2009","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.dci.2026.105680_bib16","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1101\/gad.5.5.868","article-title":"Identification and characterization of a novel repressor of beta-interferon gene expression","volume":"5","author":"Keller","year":"1991","journal-title":"Gene Dev."},{"key":"10.1016\/j.dci.2026.105680_bib17","doi-asserted-by":"crossref","DOI":"10.1155\/are\/2012468","article-title":"Emerging threat of Vibrio alginolyticus in mediterranean aquaculture: virulence, antibiotic resistance, and innovative control strategies","volume":"2026","author":"Lajnef","year":"2026","journal-title":"Aquac. Res."},{"key":"10.1016\/j.dci.2026.105680_bib18","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/raq.12104","article-title":"Physiological change and nutritional requirement of Pacific white shrimp Litopenaeus vannamei at low salinity","volume":"9","author":"Li","year":"2017","journal-title":"Rev. Aquacult."},{"key":"10.1016\/j.dci.2026.105680_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2023.109347","article-title":"The evolutionary adaptation of shrimp hemocyanin subtypes and the consequences on their structure and functions","volume":"145","author":"Li","year":"2024","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105680_bib20","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.fsi.2019.09.028","article-title":"A new crustin is involved in the innate immune response of shrimp Litopenaeus vannamei","volume":"94","author":"Li","year":"2019","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105680_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2023.104652","article-title":"CgBlimp-1 inhibits granulocytes proliferation and interleukin production in the immune response of oyster Crassostrea gigas","volume":"142","author":"Li","year":"2023","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2026.105680_bib22","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.fsi.2012.05.006","article-title":"Modulation of the innate immune system in white shrimp Litopenaeus vannamei following long-term low salinity exposure","volume":"33","author":"Lin","year":"2012","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105680_bib23","doi-asserted-by":"crossref","first-page":"28508","DOI":"10.1074\/jbc.M112.356634","article-title":"Conditional inactivation of Blimp1 in adult mice promotes increased bone mass","volume":"287","author":"Miyauchi","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.dci.2026.105680_bib24","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.805260","article-title":"Conserved and unique functions of Blimp1 in immune cells","volume":"12","author":"Nadeau","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.dci.2026.105680_bib25","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1093\/nar\/27.1.29","article-title":"KEGG: kyoto encyclopedia of genes and genomes","volume":"27","author":"Ogata","year":"1999","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.dci.2026.105680_bib26","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1182\/blood-2012-12-471029","article-title":"An evolutionarily conserved program of B-cell development and activation in zebrafish","volume":"122","author":"Page","year":"2013","journal-title":"Blood"},{"key":"10.1016\/j.dci.2026.105680_bib27","doi-asserted-by":"crossref","first-page":"263","DOI":"10.4049\/jimmunol.1600409","article-title":"SLC46 family transporters facilitate cytosolic innate immune recognition of monomeric peptidoglycans","volume":"199","author":"Paik","year":"2017","journal-title":"J. Immunol."},{"issue":"1","key":"10.1016\/j.dci.2026.105680_bib28","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1038\/s41419-025-07405-6","article-title":"Blimp-1 orchestrates macrophage polarization and metabolic homeostasis via purine biosynthesis in sepsis","volume":"16","author":"Peng","year":"2025","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.dci.2026.105680_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2019.103564","article-title":"A comparative synthesis of transcriptomic analyses reveals major differences between WSSV-susceptible Litopenaeus vannamei and WSSV-refractory Macrobrachium rosenbergii","volume":"104","author":"Peruzza","year":"2020","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2026.105680_bib30","doi-asserted-by":"crossref","first-page":"2784","DOI":"10.1111\/febs.15531","article-title":"A guide to plasma membrane solute carrier proteins","volume":"288","author":"Pizzagalli","year":"2021","journal-title":"FEBS J."},{"key":"10.1016\/j.dci.2026.105680_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2024.109704","article-title":"White feces syndrome in shrimp: comprehensive understanding of immune system responses","volume":"151","author":"Priya","year":"2024","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105680_bib32","doi-asserted-by":"crossref","first-page":"eadx8105","DOI":"10.1126\/sciadv.adx8105","article-title":"BLIMP1 negatively regulates IL-2 signaling in T cells","volume":"11","author":"Roy","year":"2025","journal-title":"Sci. Adv."},{"key":"10.1016\/j.dci.2026.105680_bib33","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1182\/blood-2008-01-136440","article-title":"Spi-B inhibits human plasma cell differentiation by repressing BLIMP1 and XBP-1 expression","volume":"112","author":"Schmidlin","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.dci.2026.105680_bib34","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1146\/annurev-immunol-101320-031555","article-title":"Functional hallmarks of healthy macrophage responses: their regulatory basis and disease relevance","volume":"40","author":"Sheu","year":"2022","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.dci.2026.105680_bib35","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1083\/jcb.200106025","article-title":"Synergistic effects of MAP2 and MAP1B knockout in neuronal migration, dendritic outgrowth, and microtubule organization","volume":"155","author":"Teng","year":"2001","journal-title":"JCB (J. Cell Biol.)"},{"key":"10.1016\/j.dci.2026.105680_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2023.105088","article-title":"Identification of an essential role against shrimp pathogens of prophenoloxidase activating enzyme 1 (PPAE1) from Fenneropenaeus merguiensis hemocytes","volume":"151","author":"Thongsoi","year":"2024","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2026.105680_bib37","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.fsi.2018.10.005","article-title":"Identification of an anti-lipopolysaccharide factor AV-R isoform (LvALF AV-R) related to Vp_PirAB-like toxin resistance in litopenaeus vannamei","volume":"84","author":"Tinwongger","year":"2019","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105680_bib38","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.mcn.2011.10.003","article-title":"MAP1B enhances microtubule assembly rates and axon extension rates in developing neurons","volume":"49","author":"Tymanskyj","year":"2012","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.dci.2026.105680_bib39","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1016\/j.bbagrm.2015.07.012","article-title":"Direct and positive regulation of Caenorhabditis elegans bed-3 by PRDM1\/BLIMP1 ortholog BLMP-1","volume":"1849","author":"Yang","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.dci.2026.105680_bib40","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.80127","article-title":"Single-cell RNA sequencing analysis of shrimp immune cells identifies macrophage-like phagocytes","volume":"11","author":"Yang","year":"2022","journal-title":"eLife"},{"key":"10.1016\/j.dci.2026.105680_bib41","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.fsi.2022.03.004","article-title":"Transcriptome analysis of Pacific white shrimp (Litopenaeus vannamei) hepatopancreas challenged by Vibrio alginolyticus reveals lipid metabolic disturbance","volume":"123","author":"Yin","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105680_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2024.105265","article-title":"Studies on immunological characteristics and transcriptomic analysis of Litopenaeus vannamei low salt-tolerance family","volume":"161","author":"Zhu","year":"2024","journal-title":"Dev. Comp. Immunol."}],"container-title":["Developmental & Comparative Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145305X26001369?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145305X26001369?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T11:23:03Z","timestamp":1786015383000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0145305X26001369"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":41,"alternative-id":["S0145305X26001369"],"URL":"https:\/\/doi.org\/10.1016\/j.dci.2026.105680","relation":{},"ISSN":["0145-305X"],"issn-type":[{"value":"0145-305X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification of genes directly regulated by LvBlimp1 in shrimp macrophage-like phagocytes","name":"articletitle","label":"Article Title"},{"value":"Developmental & Comparative Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dci.2026.105680","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"105680"}}