{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T21:31:53Z","timestamp":1793309513389,"version":"4.5.0"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012165","name":"Key Technologies Research and Development Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012165","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental & Comparative Immunology"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.dci.2026.105751","type":"journal-article","created":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T06:18:27Z","timestamp":1792563507000},"page":"105751","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Molecular characterizing and expression analysis of MCSF and its receptor in largemouth bass (Micropterus salmoides) and spotted sea bass (Lateolabrax maculatus)"],"prefix":"10.1016","volume":"184","author":[{"given":"Erqin","family":"Bao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yushuai","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhitao","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dezhong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenbang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huanxin","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingling","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.dci.2026.105751_bib1","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1038\/icb.1966.28","article-title":"The growth of mouse bone marrow cells in vitro","volume":"44","author":"Bradley","year":"1966","journal-title":"Aust. J. Exp. Biol. Med. Sci."},{"issue":"5079","key":"10.1016\/j.dci.2026.105751_bib2","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1038\/213926a0","article-title":"Stimulation by leukaemic sera of colony formation in solid agar cultures by proliferation of mouse bone marrow cells","volume":"213","author":"Bradley","year":"1967","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.dci.2026.105751_bib3","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.fsi.2015.04.029","article-title":"Identification and functional characterization of the CSF1R gene from grass carp Ctenopharyngodon idellus and its use as a marker of monocytes\/macrophages","volume":"45","author":"Chen","year":"2015","journal-title":"Fish Shellfish Immunol."},{"issue":"2","key":"10.1016\/j.dci.2026.105751_bib4","first-page":"96","article-title":"Molecular cloning, pathologically-correlated expression and functional characterization of the colony-stimulating factor 1 receptor (CSF-1R) gene from a teleost, Plecoglossus altivelis","volume":"37","author":"Chen","year":"2016","journal-title":"Zool. Res."},{"key":"10.1016\/j.dci.2026.105751_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2024.740774","article-title":"Effects of dietary binder sources on growth, digestive enzymes activity, and gut barrier function and microbial composition of larval largemouth bass (Micropterus salmoides)","volume":"586","author":"Chen","year":"2024","journal-title":"Aquaculture"},{"issue":"1","key":"10.1016\/j.dci.2026.105751_bib6","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1182\/blood.V99.1.111","article-title":"Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects","volume":"99","author":"Dai","year":"2002","journal-title":"Blood"},{"issue":"2","key":"10.1016\/j.dci.2026.105751_bib7","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.fsi.2013.04.019","article-title":"Cloning and expression analysis of grouper (Epinephelus coioides) M-CSFR gene post Cryptocaryon irritans infection and distribution of M-CSFR+ cells","volume":"35","author":"Dan","year":"2013","journal-title":"Fish Shellfish Immunol."},{"issue":"3","key":"10.1016\/j.dci.2026.105751_bib8","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1182\/blood.V58.3.630.630","article-title":"Human colony-stimulating factor (CSF-1) radioimmunoassay: resolution of three subclasses of human colony-stimulating factors","volume":"58","author":"Das","year":"1981","journal-title":"Blood"},{"key":"10.1016\/j.dci.2026.105751_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2024.741178","article-title":"Unveiling the molecular regulatory mechanisms of immune responses in the spleen of spotted sea bass (Lateolabrax maculatus) against Nocardia seriolae infection","volume":"592","author":"Dong","year":"2024","journal-title":"Aquaculture"},{"issue":"5","key":"10.1016\/j.dci.2026.105751_bib10","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1189\/jlb.1209780","article-title":"Editorial: CSF1R, CSF-1, and IL-34, a \"menage a trois\" conserved across vertebrates","volume":"87","author":"Droin","year":"2010","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.dci.2026.105751_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2024.105169","article-title":"Cloning and expression analysis of Janus activated kinase family genes from spotted seabass (Lateolabrax maculatus)","volume":"157","author":"Fan","year":"2024","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2026.105751_bib12","article-title":"Comprehensive profiling of lncRNAs in the immune response of largemouth bass to Nocardia seriolae infection","volume":"7","author":"Fu","year":"2024","journal-title":"Comparative Immunol. Rep."},{"key":"10.1016\/j.dci.2026.105751_bib13","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1235370","article-title":"Molecular characterization, gene expression and functional analysis of goldfish (Carassius auratus L.) macrophage colony stimulating factor 2","volume":"14","author":"Gouife","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.dci.2026.105751_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2020.103920","article-title":"Macrophage colony stimulating factor (MCSF) of Japanese flounder (Paralichthys olivaceus): immunoregulatory property, anti-infectious function, and interaction with MCSF receptor","volume":"116","author":"Gu","year":"2021","journal-title":"Dev. Comp. Immunol."},{"issue":"44","key":"10.1016\/j.dci.2026.105751_bib15","doi-asserted-by":"crossref","first-page":"31865","DOI":"10.1074\/jbc.M706278200","article-title":"Growth factors of lower vertebrates: characterization of goldfish (Carassius auratus L.) macrophage colony-stimulating factor-1","volume":"282","author":"Hanington","year":"2007","journal-title":"J. Biol. Chem."},{"issue":"5","key":"10.1016\/j.dci.2026.105751_bib16","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1182\/bloodadvances.2021005459","article-title":"M-CSFR\/CSF1R signaling regulates myeloid fates in zebrafish via distinct action of its receptors and ligands","volume":"6","author":"Hason","year":"2022","journal-title":"Blood Adv."},{"issue":"3","key":"10.1016\/j.dci.2026.105751_bib17","doi-asserted-by":"crossref","DOI":"10.1111\/raq.70048","article-title":"China's spotted sea bass aquaculture: advances and further goals","volume":"17","author":"Huang","year":"2025","journal-title":"Rev. Aquacult."},{"issue":"3","key":"10.1016\/j.dci.2026.105751_bib18","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.fsi.2011.12.003","article-title":"Colony-stimulating factor-1 receptor protein expression is a specific marker for goldfish (Carassius auratus L.) macrophage progenitors and their differentiated cell types","volume":"32","author":"Katzenback","year":"2012","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105751_bib19","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3354\/dao03517","article-title":"Nocardia seriolae: a serious threat to the largemouth bass Micropterus salmoides industry in Southwest China","volume":"142","author":"Lei","year":"2020","journal-title":"Dis. Aquat. Org."},{"key":"10.1016\/j.dci.2026.105751_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2023.108641","article-title":"Isolation, identification and the pathogenicity characterization of a Santee-Cooper ranavirus and its activation on immune responses in juvenile largemouth bass (Micropterus salmoides)","volume":"135","author":"Liu","year":"2023","journal-title":"Fish Shellfish Immunol."},{"issue":"4","key":"10.1016\/j.dci.2026.105751_bib21","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.str.2012.02.010","article-title":"Structural basis for the dual recognition of helical cytokines IL-34 and CSF-1 by CSF-1R","volume":"20","author":"Ma","year":"2012","journal-title":"Structure"},{"key":"10.1016\/j.dci.2026.105751_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2025.110985","article-title":"Isolation and identification of Edwardsiella tarda from naturally diseased largemouth bass (Micropterus salmoides) and its impact on host immune responses","volume":"168","author":"Ma","year":"2026","journal-title":"Fish Shellfish Immunol."},{"issue":"11","key":"10.1016\/j.dci.2026.105751_bib23","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1016\/j.dci.2009.07.003","article-title":"Characterization of zebrafish larval inflammatory macrophages","volume":"33","author":"Mathias","year":"2009","journal-title":"Dev. Comp. Immunol."},{"issue":"1","key":"10.1016\/j.dci.2026.105751_bib24","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.fsi.2014.12.023","article-title":"Grouper (Epinephelus coioides) IL-34\/MCSF2 and MCSFR1\/MCSFR2 were involved in mononuclear phagocytes activation against Cryptocaryon irritans infection","volume":"43","author":"Mo","year":"2015","journal-title":"Fish Shellfish Immunol."},{"issue":"3","key":"10.1016\/j.dci.2026.105751_bib25","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/0014-4827(66)90026-7","article-title":"The induction of clones of normal mast cells by a substance from conditioned medium","volume":"43","author":"Pluznik","year":"1966","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.dci.2026.105751_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2023.108534","article-title":"Transcriptome analysis of largemouth bass (Micropterus salmoides) challenged with LPS and polyI:C","volume":"133","author":"Qi","year":"2023","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105751_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2023.739538","article-title":"Isolation and identification of a new strain Micropterus salmoides rhabdovirus (MSRV) from largemouth bass Micropterus salmoides in China","volume":"572","author":"Qin","year":"2023","journal-title":"Aquaculture"},{"issue":"3","key":"10.1016\/j.dci.2026.105751_bib28","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1182\/blood.V33.3.396.396","article-title":"Stimulation of bone marrow colony growth in vitro by human urine","volume":"33","author":"Robinson","year":"1969","journal-title":"Blood"},{"issue":"9","key":"10.1016\/j.dci.2026.105751_bib29","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1016\/j.molimm.2005.07.028","article-title":"The colony-stimulating factor-1 receptor is a specific marker of macrophages from the bony fish gilthead seabream","volume":"43","author":"Roca","year":"2006","journal-title":"Mol. Immunol."},{"issue":"12","key":"10.1016\/j.dci.2026.105751_bib30","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1016\/j.dci.2011.11.009","article-title":"Mucosal immunoglobulins and B cells of teleost fish","volume":"35","author":"Salinas","year":"2011","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.dci.2026.105751_bib35","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2023.1275935","article-title":"Differential regulation of microglial states by colony stimulating factors","volume":"17","author":"Stanley","year":"2023","journal-title":"Front. Cell. Neurosci."},{"issue":"6","key":"10.1016\/j.dci.2026.105751_bib31","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a021857","article-title":"CSF-1 receptor signaling in myeloid cells","volume":"6","author":"Stanley","year":"2014","journal-title":"Cold Spring Harbor Perspect. Biol."},{"issue":"3","key":"10.1016\/j.dci.2026.105751_bib34","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1084\/jem.143.3.631","article-title":"Factors regulating macrophage production and growth: identity of colony-stimulating factor and macrophage growth factor","volume":"143","author":"Stanley","year":"1976","journal-title":"J. Exp. Med."},{"issue":"3","key":"10.1016\/j.dci.2026.105751_bib32","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/0022-1759(81)90156-3","article-title":"Methods for the purification, assay, characterization and target cell binding of a colony stimulating factor (CSF-1)","volume":"42","author":"Stanley","year":"1981","journal-title":"J. Immunol. Methods"},{"issue":"12","key":"10.1016\/j.dci.2026.105751_bib33","doi-asserted-by":"crossref","first-page":"4305","DOI":"10.1016\/S0021-9258(17)40265-1","article-title":"Factors regulating macrophage production and growth. Purification and some properties of the colony stimulating factor from medium conditioned by mouse L cells","volume":"252","author":"Stanley","year":"1977","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.dci.2026.105751_bib36","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s10911-014-9320-1","article-title":"CSF-1R signaling in health and disease: a focus on the mammary gland","volume":"19","author":"Sullivan","year":"2014","journal-title":"J. Mammary Gland Biol. Neoplasia"},{"issue":"4","key":"10.1016\/j.dci.2026.105751_bib37","doi-asserted-by":"crossref","first-page":"153","DOI":"10.3390\/fishes10040153","article-title":"Transcriptome analysis of immune response against Edwardsiella tarda infection in spotted sea bass (Lateolabrax maculatus)","volume":"10","author":"Sun","year":"2025","journal-title":"Fishes"},{"issue":"Part 2","key":"10.1016\/j.dci.2026.105751_bib38","article-title":"Real-time visualization of Nocardia seriolae proliferation and macrophage migration in the Northern snakehead (Channa argus)","volume":"613","author":"Teng","year":"2026","journal-title":"Aquaculture"},{"key":"10.1016\/j.dci.2026.105751_bib39","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/j.fsi.2022.06.048","article-title":"Blunt snout bream (Megalobrama amblycephala) MaCSF-1 contributes to proliferation, phagocytosis and immunoregulation of macrophages via MaCSF-1R","volume":"127","author":"Wang","year":"2022","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105751_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2024.110036","article-title":"Characterization of two novel MCSFR paralogues in rainbow trout Oncorhynchus mykiss: new insights into the molecular mechanism underlying macrophage differentiation and modulation in fish","volume":"156","author":"Wangkahart","year":"2025","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.dci.2026.105751_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2023.108565","article-title":"Repurposing of pexidartinib for microglia depletion and renewal","volume":"253","author":"Weyer","year":"2024","journal-title":"Pharmacol. Therapeut."},{"issue":"5","key":"10.1016\/j.dci.2026.105751_bib42","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1111\/jfb.15702","article-title":"Diet with optimal glutathione supplement improves growth, nonspecific immunity, intestinal microbiota, and antioxidant ability in Micropterus salmoides","volume":"104","author":"Xiong","year":"2024","journal-title":"J. Fish. Biol."},{"key":"10.1016\/j.dci.2026.105751_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2022.105815","article-title":"Co-infections of Aeromonas veronii and Nocardia seriolae in largemouth bass (Micropterus salmoides)","volume":"173","author":"Xu","year":"2022","journal-title":"Microb. Pathog."},{"issue":"2","key":"10.1016\/j.dci.2026.105751_bib44","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1007\/s12026-022-09330-8","article-title":"Macrophage subsets and their role: co-relation with colony-stimulating factor-1 receptor and clinical relevance","volume":"71","author":"Yadav","year":"2023","journal-title":"Immunol. Res."},{"key":"10.1016\/j.dci.2026.105751_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2020.735363","article-title":"A new ranavirus of the Santee-Cooper group invades largemouth bass (Micropterus salmoides) culture in southwest China","volume":"526","author":"Zhao","year":"2020","journal-title":"Aquaculture"},{"issue":"11","key":"10.1016\/j.dci.2026.105751_bib46","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0112918","article-title":"Poly(I:C) induces antiviral immune responses in Japanese flounder (Paralichthys olivaceus) that require TLR3 and MDA5 and is negatively regulated by Myd88","volume":"9","author":"Zhou","year":"2014","journal-title":"PLoS One"}],"container-title":["Developmental & Comparative Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145305X26002077?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145305X26002077?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T20:54:53Z","timestamp":1793307293000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0145305X26002077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":46,"alternative-id":["S0145305X26002077"],"URL":"https:\/\/doi.org\/10.1016\/j.dci.2026.105751","relation":{},"ISSN":["0145-305X"],"issn-type":[{"value":"0145-305X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Molecular characterizing and expression analysis of MCSF and its receptor in largemouth bass (Micropterus salmoides) and spotted sea bass (Lateolabrax maculatus)","name":"articletitle","label":"Article Title"},{"value":"Developmental & Comparative Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dci.2026.105751","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"105751"}}