{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T22:22:29Z","timestamp":1776723749610,"version":"3.51.2"},"reference-count":37,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"CDTI (Center for the Development of Industrial Technology)"},{"name":"DENTAID"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Dental Materials"],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.1016\/j.dental.2017.01.013","type":"journal-article","created":{"date-parts":[[2017,2,23]],"date-time":"2017-02-23T12:20:33Z","timestamp":1487852433000},"page":"446-453","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["Response to antiseptic agents of periodontal pathogens in in vitro biofilms on titanium and zirconium surfaces"],"prefix":"10.1016","volume":"33","author":[{"given":"M.C.","family":"S\u00e1nchez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Llama-Palacios","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Figuero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Herrera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Sanz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.dental.2017.01.013_bib0005","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/978-3-319-11038-7_4","article-title":"Peri-implant infections of oral biofilm etiology","volume":"830","author":"Belibasakis","year":"2015","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.dental.2017.01.013_bib0010","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1097\/ID.0b013e3181effa53","article-title":"Biofilm related to dental implants","volume":"19","author":"Lee","year":"2010","journal-title":"Implant Dent"},{"key":"10.1016\/j.dental.2017.01.013_bib0015","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1177\/0022034510368644","article-title":"Biofilm formation on dental restorative and implant materials","volume":"89","author":"Busscher","year":"2010","journal-title":"J Dent Res"},{"issue":"Suppl. 11","key":"10.1016\/j.dental.2017.01.013_bib0020","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1111\/j.1600-051X.2010.01674.x","article-title":"Periimplant diseases: where are we now?\u2013Consensus of the Seventh European Workshop on Periodontology","volume":"38","author":"Lang","year":"2011","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.dental.2017.01.013_bib0025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1034\/j.1600-0501.2002.130101.x","article-title":"Infectious risks for oral implants: a review of the literature","volume":"13","author":"Quirynen","year":"2002","journal-title":"Clin Oral Implants Res"},{"key":"10.1016\/j.dental.2017.01.013_bib0030","first-page":"313","article-title":"Streptococcus mutans biofilm formation and release of fluoride from experimental resin-based composites depending on surface treatment and S-PRG filler particle fraction","volume":"16","author":"Hahnel","year":"2014","journal-title":"J Adhes Dent"},{"key":"10.1016\/j.dental.2017.01.013_bib0035","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1111\/clr.12454","article-title":"Biofilm formation on the surface of modern implant abutment materials","volume":"26","author":"Hahnel","year":"2015","journal-title":"Clin Oral Implants Res"},{"key":"10.1016\/j.dental.2017.01.013_bib0040","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1902\/jop.1994.65.2.162","article-title":"The influence of surface-free energy on supra- and subgingival plaque microbiology. An in vivo study on implants","volume":"65","author":"Quirynen","year":"1994","journal-title":"J Periodontol"},{"key":"10.1016\/j.dental.2017.01.013_bib0045","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1590\/1678-7757201302312","article-title":"Polyspecies biofilm formation on implant surfaces with different surface characteristics","volume":"21","author":"Schmidlin","year":"2013","journal-title":"J Appl Oral Sci"},{"key":"10.1016\/j.dental.2017.01.013_bib0050","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/j.dental.2014.04.001","article-title":"Soft tissue integration versus early biofilm formation on different dental implant materials","volume":"30","author":"Zhao","year":"2014","journal-title":"Dent Mater"},{"key":"10.1016\/j.dental.2017.01.013_bib0055","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.colsurfb.2004.08.002","article-title":"Surface free energy and bacterial retention to saliva-coated dental implant materials\u2013an in vitro study","volume":"39","author":"Mabboux","year":"2004","journal-title":"Colloids Surf B Biointerfaces"},{"key":"10.1016\/j.dental.2017.01.013_bib0060","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.jdent.2011.12.006","article-title":"Surface properties of titanium and zirconia dental implant materials and their effect on bacterial adhesion","volume":"40","author":"Al-Radha","year":"2012","journal-title":"J Dent"},{"key":"10.1016\/j.dental.2017.01.013_bib0065","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.colsurfb.2004.11.010","article-title":"Retention of microbial cells in substratum surface features of micrometer and sub-micrometer dimensions","volume":"41","author":"Whitehead","year":"2005","journal-title":"Colloids Surf B Biointerfaces"},{"issue":"Suppl. 2","key":"10.1016\/j.dental.2017.01.013_bib0070","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1111\/j.1600-0501.2006.01353.x","article-title":"Effect of material characteristics and\/or surface topography on biofilm development","volume":"17","author":"Teughels","year":"2006","journal-title":"Clin Oral Implants Res"},{"key":"10.1016\/j.dental.2017.01.013_bib0075","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1111\/clr.12354","article-title":"The influence of surface nanoroughness, texture and chemistry of TiZr implant abutment on oral biofilm accumulation","volume":"26","author":"Xing","year":"2015","journal-title":"Clin Oral Implants Res"},{"key":"10.1016\/j.dental.2017.01.013_bib0080","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1016\/j.biomaterials.2009.09.081","article-title":"The relationship between the nanostructure of titanium surfaces and bacterial attachment","volume":"31","author":"Puckett","year":"2010","journal-title":"Biomaterials"},{"key":"10.1016\/j.dental.2017.01.013_bib0085","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1111\/cid.12140","article-title":"Modified implant surface with slower and less initial biofilm formation","volume":"17","author":"John","year":"2015","journal-title":"Clin Implant Dent Relat Res"},{"key":"10.1016\/j.dental.2017.01.013_bib0090","doi-asserted-by":"crossref","first-page":"035007","DOI":"10.1088\/1748-6041\/9\/3\/035007","article-title":"In vitro evaluation of a multispecies oral biofilm on different implant surfaces","volume":"9","author":"Violant","year":"2014","journal-title":"Biomed Mater"},{"key":"10.1016\/j.dental.2017.01.013_bib0095","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/j.dental.2014.07.008","article-title":"An in vitro biofilm model associated to dental implants: structural and quantitative analysis of in vitro biofilm formation on different dental implant surfaces","volume":"30","author":"Sanchez","year":"2014","journal-title":"Dent Mater"},{"key":"10.1016\/j.dental.2017.01.013_bib0100","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.prosdent.2015.09.016","article-title":"Structural and quantitative analysis of a mature anaerobic biofilm on different implant abutment surfaces","volume":"115","author":"de Avila","year":"2015","journal-title":"J Prosthet Dent"},{"issue":"Suppl. 12","key":"10.1016\/j.dental.2017.01.013_bib0105","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1111\/j.1600-051X.2011.01832.x","article-title":"Systematic review of quality of reporting, outcome measurements and methods to study efficacy of preventive and therapeutic approaches to peri-implant diseases","volume":"39","author":"Graziani","year":"2012","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.dental.2017.01.013_bib0110","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1111\/j.1600-0501.2009.01734.x","article-title":"Osseointegration of zirconia and titanium dental implants: a histological and histomorphometrical study in the maxilla of pigs","volume":"20","author":"Gahlert","year":"2009","journal-title":"Clin Oral Implants Res"},{"key":"10.1016\/j.dental.2017.01.013_bib0115","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1111\/j.1600-0765.2010.01341.x","article-title":"Structure, viability and bacterial kinetics of an in vitro biofilm model using six bacteria from the subgingival microbiota","volume":"46","author":"Sanchez","year":"2011","journal-title":"J Periodontal Res"},{"key":"10.1016\/j.dental.2017.01.013_bib0120","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1111\/jre.12073","article-title":"Quantitative real-time PCR combined with propidium monoazide for the selective quantification of viable periodontal pathogens in an in vitro subgingival biofilm model","volume":"49","author":"Sanchez","year":"2014","journal-title":"J Periodontal Res"},{"key":"10.1016\/j.dental.2017.01.013_bib0125","first-page":"793","article-title":"Bacterial colonization of zirconia ceramic surfaces: an in vitro and in vivo study","volume":"17","author":"Rimondini","year":"2002","journal-title":"Int J Oral Maxillofac Implants"},{"key":"10.1016\/j.dental.2017.01.013_bib0130","doi-asserted-by":"crossref","first-page":"217","DOI":"10.5051\/jpis.2012.42.6.217","article-title":"Bacterial adhesion and colonization differences between zirconia and titanium implant abutments: an in vivo human study","volume":"42","author":"de Oliveira","year":"2013","journal-title":"J Periodontal Implant Sci"},{"key":"10.1016\/j.dental.2017.01.013_bib0135","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.11607\/jomi.3142","article-title":"Essential oils and zirconia dental implant materials","volume":"28","author":"Al-Radha","year":"2013","journal-title":"Int J Oral Maxillofac Implants"},{"key":"10.1016\/j.dental.2017.01.013_bib0140","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1007\/s00284-010-9727-x","article-title":"Comparative effect of chlorhexidine and some mouthrinses on bacterial biofilm formation on titanium surface","volume":"62","author":"Baffone","year":"2011","journal-title":"Curr Microbiol"},{"key":"10.1016\/j.dental.2017.01.013_bib0145","doi-asserted-by":"crossref","first-page":"164267","DOI":"10.1155\/2013\/164267","article-title":"Oil Essential Mouthwashes Antibacterial Activity against Aggregatibacter actinomycetemcomitans: a comparison between Antibiofilm and Antiplanktonic effects","volume":"2013","author":"Erriu","year":"2013","journal-title":"Int J Dent"},{"key":"10.1016\/j.dental.2017.01.013_bib0150","first-page":"30","article-title":"Antiseptics and microcosm biofilm formation on titanium surfaces","author":"Verardi","year":"2016","journal-title":"Braz Oral Res"},{"key":"10.1016\/j.dental.2017.01.013_bib0155","first-page":"107","article-title":"Effects of subgingival chlorhexidine irrigation on peri-implant maintenance","volume":"10","author":"Felo","year":"1997","journal-title":"Am J Dent"},{"key":"10.1016\/j.dental.2017.01.013_bib0160","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/j.1600-0501.2010.02078.x","article-title":"Anti-infective treatment of peri-implant mucositis: a randomised controlled clinical trial","volume":"22","author":"Heitz-Mayfield","year":"2011","journal-title":"Clin Oral Implants Res"},{"key":"10.1016\/j.dental.2017.01.013_bib0165","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1902\/jop.2002.73.10.1118","article-title":"Clinical response to 2 different therapeutic regimens to treat peri-implant mucositis","volume":"73","author":"Porras","year":"2002","journal-title":"J Periodontol"},{"key":"10.1016\/j.dental.2017.01.013_bib0170","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1111\/j.1600-0501.2009.01861.x","article-title":"Comparison of two full-mouth approaches in the treatment of peri-implant mucositis: a pilot study","volume":"21","author":"Thone-Muhling","year":"2010","journal-title":"Clin Oral Implants Res"},{"key":"10.1016\/j.dental.2017.01.013_bib0175","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1902\/jop.1995.66.11.962","article-title":"The effect of an antiseptic mouthrinse on implant maintenance: plaque and peri-implant gingival tissues","volume":"66","author":"Ciancio","year":"1995","journal-title":"J Periodontol"},{"key":"10.1016\/j.dental.2017.01.013_bib0180","doi-asserted-by":"crossref","first-page":"101","DOI":"10.14219\/jada.archive.2000.0028","article-title":"The efficacy of a counter-rotational powered toothbrush in the maintenance of endosseous dental implants","volume":"131","author":"Truhlar","year":"2000","journal-title":"J Am Dent Assoc"},{"key":"10.1016\/j.dental.2017.01.013_bib0185","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/sj.ebd.6400915","article-title":"Chlorhexidine mouthwash reduces plaque and gingivitis","volume":"14","author":"Herrera","year":"2013","journal-title":"Evid Based Dent"}],"container-title":["Dental Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0109564116305231?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0109564116305231?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T20:24:52Z","timestamp":1758831892000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0109564116305231"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":37,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,4]]}},"alternative-id":["S0109564116305231"],"URL":"https:\/\/doi.org\/10.1016\/j.dental.2017.01.013","relation":{},"ISSN":["0109-5641"],"issn-type":[{"value":"0109-5641","type":"print"}],"subject":[],"published":{"date-parts":[[2017,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Response to antiseptic agents of periodontal pathogens in in vitro biofilms on titanium and zirconium surfaces","name":"articletitle","label":"Article Title"},{"value":"Dental Materials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dental.2017.01.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 The Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}