{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T09:57:54Z","timestamp":1783418274722,"version":"3.54.6"},"reference-count":71,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Dental Materials"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.dental.2023.07.002","type":"journal-article","created":{"date-parts":[[2023,7,21]],"date-time":"2023-07-21T03:55:40Z","timestamp":1689911740000},"page":"820-830","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["48-month clinical evaluation of a copper-containing universal adhesive in non-carious cervical lesions: A double-blind randomised clinical trial"],"prefix":"10.1016","volume":"39","author":[{"given":"Thalita P.","family":"Matos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0778-0738","authenticated-orcid":false,"given":"Romina","family":"\u00d1aupari-Villasante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patr\u00edcia Valeria Manozzo","family":"Kunz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viviane","family":"Hass","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6798-2094","authenticated-orcid":false,"given":"Alessandra","family":"Reis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario F.","family":"Guti\u00e9rrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro D.","family":"Loguercio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.dental.2023.07.002_bib1","first-page":"7","article-title":"From Buonocore's Pioneering Acid-Etch Technique to Self-Adhering Restoratives. A Status Perspective of Rapidly Advancing Dental Adhesive Technology","volume":"22","author":"Van Meerbeek","year":"2020","journal-title":"J Adhes Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib2","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1002\/jbm.b.34305","article-title":"Universal dental adhesives: current status, laboratory testing, and clinical performance","volume":"107","author":"Nagarkar","year":"2019","journal-title":"J Biomed Mater Res B Appl Biomater"},{"key":"10.1016\/j.dental.2023.07.002_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.dental.2010.10.016","article-title":"State of the art etch-and-rinse adhesives","volume":"27","author":"Pashley","year":"2011","journal-title":"Dent Mater"},{"key":"10.1016\/j.dental.2023.07.002_bib4","doi-asserted-by":"crossref","unstructured":"Cardoso M.V., de Almeida Neves A., Mine A., Coutinho E., Van Landuyt K., De Munck J., et al. Current aspects on bonding effectiveness and stability in adhesive dentistry. Aust Dent J. 2011;56 Suppl 1:31\u201344. https:\/\/doi.org\/10.1111\/j.1834\u20137819.2011.01294.x.","DOI":"10.1111\/j.1834-7819.2011.01294.x"},{"key":"10.1016\/j.dental.2023.07.002_bib5","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.dental.2010.10.023","article-title":"State of the art of self-etch adhesives","volume":"27","author":"Van Meerbeek","year":"2011","journal-title":"Dent Mater"},{"key":"10.1016\/j.dental.2023.07.002_bib6","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1590\/0103-6440201302442","article-title":"Self-etch adhesive systems: a literature review","volume":"26","author":"Giannini","year":"2015","journal-title":"Braz Dent J"},{"key":"10.1016\/j.dental.2023.07.002_bib7","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/j.dental.2014.07.006","article-title":"Dentin-smear remains at self-etch adhesive interface","volume":"30","author":"Mine","year":"2014","journal-title":"Dent Mater"},{"key":"10.1016\/j.dental.2023.07.002_bib8","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jdent.2005.03.004","article-title":"Comparison of interfacial characteristics of adhesive bonding to superficial versus deep dentine using SEM and staining techniques","volume":"34","author":"Wang","year":"2006","journal-title":"J Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib9","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.jdsr.2020.08.004","article-title":"Current perspectives on dental adhesion: (1) Dentin adhesion - not there yet","volume":"56","author":"Perdig\u00e3o","year":"2020","journal-title":"Jpn Dent Sci Rev"},{"key":"10.1016\/j.dental.2023.07.002_bib10","article-title":"In vitro longevity of bonding properties of universal adhesives to dentin","author":"Munoz","year":"2014","journal-title":"Oper Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib11","first-page":"87","article-title":"How \"Universal\" is Adhesion? Shear Bond Strength of Multi-mode Adhesives to Enamel and Dentin","volume":"21","author":"Jacker-Guhr","year":"2019","journal-title":"J Adhes Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib12","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1007\/s00784-016-1966-1","article-title":"Adhesion of multimode adhesives to enamel and dentin after one year of water storage","volume":"21","author":"Vermelho","year":"2017","journal-title":"Clin Oral Invest"},{"key":"10.1016\/j.dental.2023.07.002_bib13","doi-asserted-by":"crossref","first-page":"4","DOI":"10.14295\/bds.2012.v15i1.790","article-title":"Durable bonds at the adhesive\/dentin interface: an impossible mission or simply a moving target?","volume":"15","author":"Spencer","year":"2012","journal-title":"Braz Dent Sci"},{"key":"10.1016\/j.dental.2023.07.002_bib14","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1002\/jbm.b.31295","article-title":"Host-derived loss of dentin matrix stiffness associated with solubilization of collagen","volume":"90","author":"Carrilho","year":"2009","journal-title":"J Biomed Mater Res B Appl Biomater"},{"key":"10.1016\/j.dental.2023.07.002_bib15","first-page":"243","article-title":"Dentin caries progression and the role of metalloproteinases: an update","volume":"17","author":"Femiano","year":"2016","journal-title":"Eur J Paediatr Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib16","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1159\/000363582","article-title":"Matrix metalloproteinases and other matrix proteinases in relation to cariology: the era of 'dentin degradomics'","volume":"49","author":"Tjaderhane","year":"2015","journal-title":"Caries Res"},{"key":"10.1016\/j.dental.2023.07.002_bib17","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1177\/0022034513504436","article-title":"Cariogenic bacteria degrade dental resin composites and adhesives","volume":"92","author":"Bourbia","year":"2013","journal-title":"J Dent Res"},{"key":"10.1016\/j.dental.2023.07.002_bib18","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.actbio.2018.09.050","article-title":"Gene expression and protein synthesis of esterase from Streptococcus mutans are affected by biodegradation by-product from methacrylate resin composites and adhesives","volume":"81","author":"Huang","year":"2018","journal-title":"Acta Biomater"},{"key":"10.1016\/j.dental.2023.07.002_bib19","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1016\/j.dental.2018.05.008","article-title":"Biodegradation of resin-dentin interfaces is dependent on the restorative material, mode of adhesion, esterase or MMP inhibition","volume":"34","author":"Huang","year":"2018","journal-title":"Dent Mater"},{"key":"10.1016\/j.dental.2023.07.002_bib20","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.jdent.2017.05.015","article-title":"Biofilm-induced changes to the composite surface","volume":"63","author":"Nedeljkovic","year":"2017","journal-title":"J Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib21","first-page":"337","article-title":"Antibacterial dental restorative materials: a state-of-the-art review","volume":"25","author":"Chen","year":"2012","journal-title":"Am J Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib22","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1016\/j.dental.2015.08.155","article-title":"A systematic review about antibacterial monomers used in dental adhesive systems: current status and further prospects","volume":"31","author":"Cocco","year":"2015","journal-title":"Dent Mater"},{"key":"10.1016\/j.dental.2023.07.002_bib23","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.3390\/ijms16012099","article-title":"Antimicrobial polymers with metal nanoparticles","volume":"16","author":"Palza","year":"2015","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.dental.2023.07.002_bib24","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1007\/s00253-013-5422-8","article-title":"Bioactivity, mechanism of action, and cytotoxicity of copper-based nanoparticles: a review","volume":"98","author":"Ingle","year":"2014","journal-title":"Appl Microbiol Biotechnol"},{"key":"10.1016\/j.dental.2023.07.002_bib25","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.dental.2016.12.011","article-title":"Mechanical and microbiological properties and drug release modeling of an etch-and-rinse adhesive containing copper nanoparticles","volume":"33","author":"Gutierrez","year":"2017","journal-title":"Dent Mater"},{"key":"10.1016\/j.dental.2023.07.002_bib26","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0109-5641(99)00084-6","article-title":"Inhibition of human gingival gelatinases (MMP-2 and MMP-9) by metal salts","volume":"16","author":"de Souza","year":"2000","journal-title":"Dent Mater"},{"key":"10.1016\/j.dental.2023.07.002_bib27","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1016\/S0024-3205(00)00803-1","article-title":"The tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ stimulates matrix metalloproteinase-2 expression by fibroblast cultures","volume":"67","author":"Sim\u00e9on","year":"2000","journal-title":"Life Sci"},{"key":"10.1016\/j.dental.2023.07.002_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijadhadh.2022.103253","article-title":"Four-year effects of copper-nanoparticles on durability of resin-dentin interfaces","volume":"119","author":"\u00d1aupari-Villasante","year":"2022","journal-title":"Int J Adhes Adhes"},{"key":"10.1016\/j.dental.2023.07.002_bib29","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.jdent.2019.01.012","article-title":"Biological, mechanical and adhesive properties of universal adhesives containing zinc and copper nanoparticles","volume":"82","author":"Gutierrez","year":"2019","journal-title":"J Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2019.103219","article-title":"18-month clinical evaluation of a copper-containing universal adhesive in non-carious cervical lesions: A double-blind, randomized controlled trial","volume":"90","author":"Matos","year":"2019","journal-title":"J Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib31","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/1745-6215-11-32","article-title":"CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials","volume":"11","author":"Schulz","year":"2010","journal-title":"Trials"},{"key":"10.1016\/j.dental.2023.07.002_bib32","doi-asserted-by":"crossref","first-page":"113","DOI":"10.2341\/13-045-C","article-title":"A New Universal Simplified Adhesive: 18-Month Clinical Evaluation","volume":"39","author":"Perdigao","year":"2014","journal-title":"Oper Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib33","doi-asserted-by":"crossref","first-page":"7","DOI":"10.14219\/jada.archive.1964.0034","article-title":"The simplified oral hygiene index","volume":"68","author":"Greene","year":"1964","journal-title":"J Am Dent Assoc"},{"key":"10.1016\/j.dental.2023.07.002_bib34","first-page":"323","article-title":"Five-year double-blind randomized clinical evaluation of a resin-modified glass ionomer and a polyacid-modified resin in noncarious cervical lesions","volume":"5","author":"Loguercio","year":"2003","journal-title":"J Adhes Dent"},{"issue":"Suppl 1","key":"10.1016\/j.dental.2023.07.002_bib35","first-page":"S173","article-title":"Periodontitis: consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions","volume":"89","author":"Papapanou","year":"2018","journal-title":"J Periodo"},{"key":"10.1016\/j.dental.2023.07.002_bib36","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1111\/joor.12663","article-title":"International consensus on the assessment of bruxism: Report of a work in progress","volume":"45","author":"Lobbezoo","year":"2018","journal-title":"J Oral Rehabil"},{"key":"10.1016\/j.dental.2023.07.002_bib37","doi-asserted-by":"crossref","first-page":"26","DOI":"10.14219\/jada.archive.1993.0104","article-title":"Current concepts in dentin bonding: focusing on dentinal adhesion factors","volume":"124","author":"Heymann","year":"1993","journal-title":"J Am Dent Assoc"},{"key":"10.1016\/j.dental.2023.07.002_bib38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0300-5712(00)00050-6","article-title":"May KN, Jr., et al. Eighteen-month clinical evaluation of a filled and unfilled dentin adhesive","volume":"29","author":"Swift","year":"2001","journal-title":"J Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib39","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1111\/jerd.12042","article-title":"Effect of enamel bevel on the clinical performance of resin composite restorations placed in non-carious cervical lesions","volume":"25","author":"Da Costa","year":"2013","journal-title":"J Esthet Restor Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib40","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1016\/j.jdent.2014.04.003","article-title":"Comparison of pattern of failure of resin composite restorations in non-carious cervical lesions with and without occlusal wear facets","volume":"42","author":"Oginni","year":"2014","journal-title":"J Dent"},{"issue":"Suppl 1","key":"10.1016\/j.dental.2023.07.002_bib41","first-page":"121","volume":"9","author":"Hickel","year":"2007","journal-title":"J Adhes Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib42","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1111\/j.1708-8240.2005.tb00126.x","article-title":"Critical appraisal. To bevel or not in anterior composites","volume":"17","author":"Baratieri","year":"2005","journal-title":"J Esthet Restor Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib43","first-page":"13","article-title":"Esthetic anterior resin restorations: to bevel enamel or not? Odovtos","volume":"23","author":"Ram\u00edrez-Barrantes","year":"2021","journal-title":"Int J Dent Sci"},{"key":"10.1016\/j.dental.2023.07.002_bib44","first-page":"233","article-title":"Direct adhesive restoration of anterior teeth. Part 1. Fundamentals of excellence","volume":"15","author":"de Araujo J\u00fanior","year":"2003","journal-title":"Pr Proced Aesthet Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib45","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.jdent.2017.04.007","article-title":"The role of copper nanoparticles in an etch-and-rinse adhesive on antimicrobial activity, mechanical properties and the durability of resin-dentine interfaces","volume":"61","author":"Gutierrez","year":"2017","journal-title":"J Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib46","doi-asserted-by":"crossref","unstructured":"Pocock S.J. The size of a clinical trial. SJ Pocock (Ed), Clinical Trials: A Practical Approach, John Wiley & Sons, Chinchester. 2013:123\u201341.","DOI":"10.1002\/9781118793916.ch9"},{"key":"10.1016\/j.dental.2023.07.002_bib47","first-page":"259","article-title":"FDI World Dental Federation - clinical criteria for the evaluation of direct and indirect restorations. Update and clinical examples","volume":"12","author":"Hickel","year":"2010","journal-title":"J Adhes Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib48","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1080\/00016350510019874","article-title":"An 18-months' evaluation of self-etch and etch & rinse adhesive in non-carious cervical lesions","volume":"63","author":"Dalton Bittencourt","year":"2005","journal-title":"Acta Odontol Scand"},{"key":"10.1016\/j.dental.2023.07.002_bib49","doi-asserted-by":"crossref","first-page":"3","DOI":"10.2341\/11-222-C","article-title":"Randomized clinical trial of four adhesion strategies: 18-month results","volume":"37","author":"Perdigao","year":"2012","journal-title":"Oper Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmbbm.2021.105017","article-title":"A universal adhesive containing copper nanoparticles improves the stability of hybrid layer in a cariogenic oral environment: An in situ study","volume":"126","author":"Vidal","year":"2022","journal-title":"J Mech Behav Biomed Mater"},{"key":"10.1016\/j.dental.2023.07.002_bib51","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1177\/154405910708600115","article-title":"Chlorhexidine preserves dentin bond in vitro","volume":"86","author":"Carrilho","year":"2007","journal-title":"J Dent Res"},{"key":"10.1016\/j.dental.2023.07.002_bib52","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1111\/j.1600-0722.2010.00758.x","article-title":"Enzymatic degradation of adhesive-dentin interfaces produced by mild self-etch adhesives","volume":"118","author":"De Munck","year":"2010","journal-title":"Eur J Oral Sci"},{"key":"10.1016\/j.dental.2023.07.002_bib53","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.jdent.2018.12.012","article-title":"Two-year clinical evaluation of proanthocyanidins added to a two-step etch-and-rinse adhesive","volume":"81","author":"de Souza","year":"2019","journal-title":"J Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2020.103325","article-title":"Two-year clinical evaluation of a proanthocyanidins-based primer in non-carious cervical lesions: A double-blind randomized clinical trial","volume":"96","author":"de Souza","year":"2020","journal-title":"J Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib55","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.jdent.2014.07.010","article-title":"Two-year clinical evaluation of chlorhexidine incorporation in two-step self-etch adhesive","volume":"43","author":"Ara\u00fajo","year":"2015","journal-title":"J Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib56","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1016\/j.jdent.2013.09.004","article-title":"Influence of chlorhexidine digluconate on the clinical performance of adhesive restorations: a 3-year follow-up","volume":"41","author":"Sartori","year":"2013","journal-title":"J Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib57","doi-asserted-by":"crossref","first-page":"e100","DOI":"10.1016\/j.dental.2009.11.148","article-title":"Relationship between bond-strength tests and clinical outcomes","volume":"26","author":"Van Meerbeek","year":"2010","journal-title":"Dent Mater"},{"key":"10.1016\/j.dental.2023.07.002_bib58","first-page":"107","article-title":"Pooling of dentin microtensile bond strength data improves clinical correlation","volume":"13","author":"Heintze","year":"2011","journal-title":"J Adhes Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib59","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.jdent.2012.02.012","article-title":"Bonding effectiveness of a new 'multi-mode' adhesive to enamel and dentine","volume":"40","author":"Hanabusa","year":"2012","journal-title":"J Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib60","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.jdent.2015.04.005","article-title":"Does active application of universal adhesives to enamel in self-etch mode improve their performance","volume":"43","author":"Loguercio","year":"2015","journal-title":"J Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib61","doi-asserted-by":"crossref","first-page":"188","DOI":"10.2341\/17-384-L","article-title":"Effect of active application on bond durability of universal adhesives","volume":"44","author":"Moritake","year":"2019","journal-title":"Oper Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib62","doi-asserted-by":"crossref","DOI":"10.1590\/1807-3107bor-2019.vol33.0120","article-title":"Influence of the mode of application of universal adhesive systems on adhesive properties to fluorotic enamel","volume":"33","author":"Cardenas","year":"2019","journal-title":"Braz Oral Res"},{"key":"10.1016\/j.dental.2023.07.002_bib63","doi-asserted-by":"crossref","first-page":"e503","DOI":"10.1016\/j.dental.2021.08.017","article-title":"Is clinical behavior of composite restorations placed in non-carious cervical lesions influenced by the application mode of universal adhesives? A systematic review and meta-analysis","volume":"37","author":"Josic","year":"2021","journal-title":"Dent Mater"},{"key":"10.1016\/j.dental.2023.07.002_bib64","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2022.104120","article-title":"Universal Simplified Adhesive applied under different bonding technique's: 36-month Randomized Multicentre Clinical Trial","volume":"122","author":"de Albuquerque","year":"2022","journal-title":"J Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/j.dental.2020.08.007","article-title":"Five-year clinical evaluation of a universal adhesive: a randomized double-blind trial","author":"de Paris Matos","year":"2020","journal-title":"Dent Mater"},{"key":"10.1016\/j.dental.2023.07.002_bib66","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.dental.2023.04.007","article-title":"Five-year clinical evaluation of universal adhesive applied following different bonding techniques: a randomized multicenter clinical trial","volume":"39","author":"\u00d1aupari-Villasante","year":"2023","journal-title":"Dent Mater"},{"key":"10.1016\/j.dental.2023.07.002_bib67","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1177\/0022034515623741","article-title":"Paucity of nanolayering in resin-dentin interfaces of MDP-based adhesives","volume":"95","author":"Tian","year":"2016","journal-title":"J Dent Res"},{"key":"10.1016\/j.dental.2023.07.002_bib68","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1177\/0022034512437375","article-title":"Self-assembled nano-layering at the adhesive interface","volume":"91","author":"Yoshida","year":"2012","journal-title":"J Dent Res"},{"key":"10.1016\/j.dental.2023.07.002_bib69","doi-asserted-by":"crossref","first-page":"3187","DOI":"10.1016\/j.actbio.2011.04.026","article-title":"Nanolayering of phosphoric acid ester monomer on enamel and dentin","volume":"7","author":"Yoshihara","year":"2011","journal-title":"Acta Biomater"},{"key":"10.1016\/j.dental.2023.07.002_bib70","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jdent.2016.05.009","article-title":"Selective enamel etching in cervical lesions for self-etch adhesives: a systematic review and meta-analysis","volume":"53","author":"Szesz","year":"2016","journal-title":"J Dent"},{"key":"10.1016\/j.dental.2023.07.002_bib71","doi-asserted-by":"crossref","DOI":"10.1007\/s00784-022-04613-8","article-title":"Effect of an additional bonding resin on the 5-year performance of a universal adhesive: a randomized clinical trial","author":"Fuentes","year":"2022","journal-title":"Clin Oral Invest"}],"container-title":["Dental Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0109564123001574?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0109564123001574?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T22:54:30Z","timestamp":1758840870000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0109564123001574"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":71,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["S0109564123001574"],"URL":"https:\/\/doi.org\/10.1016\/j.dental.2023.07.002","relation":{},"ISSN":["0109-5641"],"issn-type":[{"value":"0109-5641","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"48-month clinical evaluation of a copper-containing universal adhesive in non-carious cervical lesions: A double-blind randomised clinical trial","name":"articletitle","label":"Article Title"},{"value":"Dental Materials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dental.2023.07.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Academy of Dental Materials. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}