{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T04:07:41Z","timestamp":1788840461330,"version":"build-2803163510"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Dental Materials"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.dental.2026.09.002","type":"journal-article","created":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T03:29:32Z","timestamp":1788838172000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Study of the effect of a photocurable bioadhesive composite hydrogel for dentin caries management"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-5952-1518","authenticated-orcid":false,"given":"Xizhe","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4956-1672","authenticated-orcid":false,"given":"Rui","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7394-569X","authenticated-orcid":false,"given":"Jiayu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1856-7649","authenticated-orcid":false,"given":"Weichang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8832-1129","authenticated-orcid":false,"given":"Qinghui","family":"Zhi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10219","key":"10.1016\/j.dental.2026.09.002_bib1","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0140-6736(19)33016-8","article-title":"Oral diseases: a global public health challenge","volume":"395","author":"Bawaskar","year":"2020","journal-title":"Lancet"},{"issue":"10194","key":"10.1016\/j.dental.2026.09.002_bib2","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0140-6736(19)31146-8","article-title":"Oral diseases: a global public health challenge","volume":"394","author":"Peres","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.dental.2026.09.002_bib3","first-page":"1","article-title":"Dental practitioners' thresholds for restorative intervention in carious lesions: a survey-based systematic review update","author":"Lundbeck","year":"2025","journal-title":"Caries Res"},{"issue":"2","key":"10.1016\/j.dental.2026.09.002_bib4","doi-asserted-by":"crossref","first-page":"221","DOI":"10.5005\/jp-journals-10005-2757","article-title":"Clinical effectiveness of high-viscosity glass ionomer cement and composite resin as a restorative material in primary teeth: a systematic review of clinical trials","volume":"17","author":"Krishnakumar","year":"2024","journal-title":"Int J Clin Pediatr Dent"},{"key":"10.1016\/j.dental.2026.09.002_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2024.105539","article-title":"Factors associated with the success of restorative treatment for root caries: a systematic review with meta-analysis","volume":"153","author":"Wen","year":"2025","journal-title":"J Dent"},{"issue":"7","key":"10.1016\/j.dental.2026.09.002_bib6","first-page":"466","article-title":"Silver diamine fluoride treatment considerations in children's caries management","volume":"38","author":"Crystal","year":"2016","journal-title":"Pediatr Dent"},{"key":"10.1016\/j.dental.2026.09.002_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.dtrs.2026.100028","article-title":"Use of fluoride varnish with functionalized tricalcium phosphate for prevention of early childhood caries: a randomised clinical trial","author":"Chen","year":"2026","journal-title":"Dent Res"},{"key":"10.1016\/j.dental.2026.09.002_bib8","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s12903-015-0033-7","article-title":"Non-surgical treatment of dentin caries in preschool children\u2013systematic review","volume":"15","author":"Duangthip","year":"2015","journal-title":"BMC Oral Health"},{"issue":"6","key":"10.1016\/j.dental.2026.09.002_bib9","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1177\/00220345241303880","article-title":"Streptococcus mutans and caries: a systematic review and meta-analysis","volume":"104","author":"Mazurel","year":"2025","journal-title":"J Dent Res"},{"issue":"1","key":"10.1016\/j.dental.2026.09.002_bib10","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/s41368-022-00167-3","article-title":"Expert consensus on dental caries management","volume":"14","author":"Cheng","year":"2022","journal-title":"Int J Oral Sci"},{"issue":"3","key":"10.1016\/j.dental.2026.09.002_bib11","doi-asserted-by":"crossref","DOI":"10.1002\/SMMD.20240020","article-title":"Developing functional hydrogels for treatment of oral diseases","volume":"3","author":"Song","year":"2024","journal-title":"Smart Med"},{"issue":"2","key":"10.1016\/j.dental.2026.09.002_bib12","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.dental.2022.12.005","article-title":"Dentin primer based on a highly functionalized gelatin-methacryloyl hydrogel","volume":"39","author":"Alia","year":"2023","journal-title":"Dent Mater"},{"issue":"5","key":"10.1016\/j.dental.2026.09.002_bib13","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1021\/acs.biomac.0c01745","article-title":"Photopolymerization of bio-based polymers in a biomedical engineering perspective","volume":"22","author":"Chiulan","year":"2021","journal-title":"Biomacromolecules"},{"issue":"24","key":"10.1016\/j.dental.2026.09.002_bib14","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202300546","article-title":"SrCuSi4 O10\/gelMA composite hydrogel-mediated vital pulp therapy: integrating antibacterial property and enhanced pulp regeneration activity","volume":"12","author":"Qiu","year":"2023","journal-title":"Adv Healthc Mater"},{"key":"10.1016\/j.dental.2026.09.002_bib15","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.actbio.2022.03.046","article-title":"ZIF-8 modified multifunctional injectable photopolymerizable GelMA hydrogel for the treatment of periodontitis","volume":"146","author":"Liu","year":"2022","journal-title":"Acta Biomater"},{"issue":"1","key":"10.1016\/j.dental.2026.09.002_bib16","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1186\/s40824-023-00422-6","article-title":"GelMA-based bioactive hydrogel scaffolds with multiple bone defect repair functions: therapeutic strategies and recent advances","volume":"27","author":"Zhou","year":"2023","journal-title":"Biomater Res"},{"issue":"4","key":"10.1016\/j.dental.2026.09.002_bib17","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202101504","article-title":"Degradable hydrogel adhesives with enhanced tissue adhesion, superior self-healing, cytocompatibility, and antibacterial property","volume":"11","author":"Yang","year":"2022","journal-title":"Adv Healthc Mater"},{"issue":"44","key":"10.1016\/j.dental.2026.09.002_bib18","doi-asserted-by":"crossref","first-page":"28767","DOI":"10.1021\/acsomega.0c04087","article-title":"Flexible ternary combination of gellan gum, sodium carboxymethyl cellulose, and silicon dioxide nanocomposites fabricated by quaternary ammonium silane: rheological, thermal, and antimicrobial properties","volume":"5","author":"Rukmanikrishnan","year":"2020","journal-title":"ACS Omega"},{"issue":"9","key":"10.1016\/j.dental.2026.09.002_bib19","doi-asserted-by":"crossref","first-page":"11507","DOI":"10.1021\/acsami.2c20401","article-title":"Biodegradable and cytocompatible hydrogel coating with antibacterial activity for the prevention of implant-associated infection","volume":"15","author":"Liu","year":"2023","journal-title":"ACS Appl Mater Interfaces"},{"key":"10.1016\/j.dental.2026.09.002_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.yrtph.2020.104717","article-title":"Human health hazard assessment of quaternary ammonium compounds: didecyl dimethyl ammonium chloride and alkyl (C12-C16) dimethyl benzyl ammonium chloride","volume":"116","author":"Luz","year":"2020","journal-title":"Regul Toxicol Pharmacol"},{"issue":"23","key":"10.1016\/j.dental.2026.09.002_bib21","doi-asserted-by":"crossref","first-page":"10750","DOI":"10.1021\/acs.jmedchem.6b01435","article-title":"Antibacterial and antibiofilm activity of cationic small molecules with spatial positioning of hydrophobicity: an in vitro and in vivo evaluation","volume":"59","author":"Hoque","year":"2016","journal-title":"J Med Chem"},{"key":"10.1016\/j.dental.2026.09.002_bib22","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.jdent.2018.12.014","article-title":"Clinical efficacy of nano-hydroxyapatite in dentin hypersensitivity: a systematic review and meta-analysis","volume":"82","author":"de Melo Alencar","year":"2019","journal-title":"J Dent"},{"key":"10.1016\/j.dental.2026.09.002_bib23","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.jdent.2017.03.001","article-title":"Comparison of in vitro dentinal tubule occluding efficacy of two different methods using a nano-scaled bioactive glass-containing desensitising agent","volume":"60","author":"Ma","year":"2017","journal-title":"J Dent"},{"issue":"4","key":"10.1016\/j.dental.2026.09.002_bib24","doi-asserted-by":"crossref","first-page":"E93","DOI":"10.2341\/15-145-C","article-title":"Treatment of dentin hypersensitivity using nano-hydroxyapatite pastes: a randomized three-month clinical trial","volume":"41","author":"Wang","year":"2016","journal-title":"Oper Dent"},{"key":"10.1016\/j.dental.2026.09.002_bib25","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.jcis.2020.10.023","article-title":"Mussel-inspired adhesive and conductive hydrogel with tunable mechanical properties for wearable strain sensors","volume":"585","author":"Zhang","year":"2021","journal-title":"J Colloid Interface Sci"},{"key":"10.1016\/j.dental.2026.09.002_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2021.103720","article-title":"In vitro evaluation of the anti-proteolytic and cross-linking effect of mussel-inspired monomer on the demineralized dentin matrix","volume":"111","author":"Li","year":"2021","journal-title":"J Dent"},{"issue":"35","key":"10.1016\/j.dental.2026.09.002_bib27","doi-asserted-by":"crossref","first-page":"12999","DOI":"10.1073\/pnas.0605552103","article-title":"Single-molecule mechanics of mussel adhesion","volume":"103","author":"Lee","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"issue":"4","key":"10.1016\/j.dental.2026.09.002_bib28","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1179\/1753555715Y.0000000048","article-title":"Effect of DOPA and dopamine coupling on protein loading of hydroxyapatite","volume":"31","author":"Ozhukil Kollath","year":"2016","journal-title":"Mat Tech"},{"issue":"10","key":"10.1016\/j.dental.2026.09.002_bib29","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/j.dental.2017.07.008","article-title":"Anti-proteolytic property and bonding durability of mussel adhesive protein-modified dentin adhesive interface","volume":"33","author":"Fang","year":"2017","journal-title":"Dent Mater"},{"issue":"16","key":"10.1016\/j.dental.2026.09.002_bib30","doi-asserted-by":"crossref","first-page":"3617","DOI":"10.1111\/bph.15193","article-title":"The ARRIVE guidelines 2.0: updated guidelines for reporting animal research","volume":"177","author":"Percie du Sert","year":"2020","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.dental.2026.09.002_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.jdent.2021.103888","article-title":"A mussel glue-inspired monomer-etchant cocktail for improving dentine bonding","volume":"116","author":"Xu","year":"2022","journal-title":"J Dent"},{"issue":"1","key":"10.1016\/j.dental.2026.09.002_bib32","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/jicd.12054","article-title":"Mussel-mimetic, bioadhesive polymers from plant-derived materials","volume":"6","author":"Hiraishi","year":"2015","journal-title":"J Investig Clin Dent"},{"issue":"5","key":"10.1016\/j.dental.2026.09.002_bib33","doi-asserted-by":"crossref","first-page":"2761","DOI":"10.3390\/ijms25052761","article-title":"Anti gram-positive bacteria activity of synthetic quaternary ammonium lipid and its precursor phosphonium salt","volume":"25","author":"Bacchetti","year":"2024","journal-title":"Int J Mol Sci"},{"issue":"Pt 2","key":"10.1016\/j.dental.2026.09.002_bib34","article-title":"Polycaprolactone\/gelatin-QAS\/bioglass nanofibres accelerate diabetic chronic wound healing by improving dysfunction of fibroblasts","volume":"283","author":"Ding","year":"2024","journal-title":"Int J Biol Macromol"},{"key":"10.1016\/j.dental.2026.09.002_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2025.140095","article-title":"Insights into interaction of quaternary ammonium salt cationic surfactants with different branched-chain lengths and DNA: multi-spectral analysis, viscosity method, and gel electrophoresis","volume":"299","author":"Zhang","year":"2025","journal-title":"Int J Biol Macromol"},{"key":"10.1016\/j.dental.2026.09.002_bib36","volume":"10","author":"Standard","year":"2009"},{"issue":"5","key":"10.1016\/j.dental.2026.09.002_bib37","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/j.archoralbio.2015.01.014","article-title":"Comparison of chemical composition of enamel and dentine in human, bovine, porcine and ovine teeth","volume":"60","author":"Teruel Jde","year":"2015","journal-title":"Arch Oral Biol"},{"issue":"1","key":"10.1016\/j.dental.2026.09.002_bib38","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1017\/S143192761401366X","article-title":"Morphological and chemical comparative analysis of the human and bovine dentin-adhesive layer","volume":"21","author":"Soares","year":"2015","journal-title":"Microsc Microanal"},{"issue":"4","key":"10.1016\/j.dental.2026.09.002_bib39","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.joen.2006.12.011","article-title":"Topographical, diametral, and quantitative analysis of dentin tubules in the root canals of human and bovine teeth","volume":"33","author":"Camargo","year":"2007","journal-title":"J Endod"}],"container-title":["Dental Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0109564126004240?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0109564126004240?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T03:29:37Z","timestamp":1788838177000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0109564126004240"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":39,"alternative-id":["S0109564126004240"],"URL":"https:\/\/doi.org\/10.1016\/j.dental.2026.09.002","relation":{},"ISSN":["0109-5641"],"issn-type":[{"value":"0109-5641","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Study of the effect of a photocurable bioadhesive composite hydrogel for dentin caries management","name":"articletitle","label":"Article Title"},{"value":"Dental Materials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dental.2026.09.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Academy of Dental Materials. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}