{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T03:52:47Z","timestamp":1788580367423,"version":"build-2803163510"},"reference-count":52,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,4,1]],"date-time":"2010-04-01T00:00:00Z","timestamp":1270080000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatologic Clinics"],"published-print":{"date-parts":[[2010,4]]},"DOI":"10.1016\/j.det.2010.01.008","type":"journal-article","created":{"date-parts":[[2010,5,5]],"date-time":"2010-05-05T07:18:40Z","timestamp":1273043920000},"page":"273-282","source":"Crossref","is-referenced-by-count":57,"title":["Pain Management in Epidermolysis Bullosa"],"prefix":"10.1016","volume":"28","author":[{"given":"Kenneth R.","family":"Goldschneider","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne W.","family":"Lucky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.det.2010.01.008_bib1","doi-asserted-by":"crossref","first-page":"143","DOI":"10.2340\/00015555-0376","article-title":"Main problems experienced by children with epidermolysis bullosa: a qualitative study with semi-structured interviews","volume":"88","author":"van Scheppingen","year":"2008","journal-title":"Acta Derm Venereol"},{"issue":"2","key":"10.1016\/j.det.2010.01.008_bib2","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1111\/j.1365-2230.2004.01428.x","article-title":"Assessment of mobility, activities and pain in different subtypes of epidermolysis bullosa","volume":"29","author":"Fine","year":"2004","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.det.2010.01.008_bib3","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1111\/j.1365-2133.2009.09347.x","article-title":"Quality of life evaluation in epidermolysis bullosa (EB) through the development of the QOLEB questionnaire: an EB-specific quality of life instrument","volume":"161","author":"Frew","year":"2009","journal-title":"Br J Dermatol"},{"issue":"8","key":"10.1016\/j.det.2010.01.008_bib4","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1111\/j.1365-4632.2007.03316.x","article-title":"Medical management of epidermolysis bullosa: proceedings of the IInd international symposium on epidermolysis bullosa, Santiago, Chile, 2005","volume":"46","author":"Mellerio","year":"2007","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.det.2010.01.008_bib5","series-title":"Pain in children: a practical guide for primary care","year":"2008"},{"issue":"5","key":"10.1016\/j.det.2010.01.008_bib6","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1111\/j.1365-2133.2005.07123.x","article-title":"Bone mineralization in children with epidermolysis bullosa","volume":"154","author":"Fewtrell","year":"2006","journal-title":"Br J Dermatol"},{"issue":"1","key":"10.1016\/j.det.2010.01.008_bib7","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1001\/archdermatol.2008.536","article-title":"Severe symptomatic hypocalcemia in a patient with RDEB treated with intravenous zoledronic acid","volume":"145","author":"Perman","year":"2009","journal-title":"Arch Dermatol"},{"issue":"6","key":"10.1016\/j.det.2010.01.008_bib8","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1111\/j.1365-2133.2008.08507.x","article-title":"Gastrointestinal complications of epidermolysis bullosa in children","volume":"158","author":"Freeman","year":"2008","journal-title":"Br J Dermatol"},{"issue":"5 Pt 1","key":"10.1016\/j.det.2010.01.008_bib9","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.1097\/01.ju.0000143200.86683.2c","article-title":"Genitourinary complications of inherited epidermolysis bullosa: experience of the national epidermolysis bullosa registry and review of the literature","volume":"172","author":"Fine","year":"2004","journal-title":"J Urol"},{"issue":"11","key":"10.1016\/j.det.2010.01.008_bib10","doi-asserted-by":"crossref","first-page":"482","DOI":"10.12968\/jowc.2008.17.11.31476","article-title":"Dressings used in epidermolysis bullosa blister wounds: a review","volume":"17","author":"Ly","year":"2008","journal-title":"J Wound Care"},{"issue":"10","key":"10.1016\/j.det.2010.01.008_bib11","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1001\/archderm.136.10.1225","article-title":"Tissue-engineered skin (Apligraf) in the healing of patients with epidermolysis bullosa wounds","volume":"136","author":"Falabella","year":"2000","journal-title":"Arch Dermatol"},{"issue":"6","key":"10.1016\/j.det.2010.01.008_bib12","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1067\/mjd.2003.502","article-title":"Graftskin therapy in epidermolysis bullosa","volume":"48","author":"Fivenson","year":"2003","journal-title":"J Am Acad Dermatol"},{"issue":"11","key":"10.1016\/j.det.2010.01.008_bib13","first-page":"22","article-title":"Using a dermal skin substitute in the treatment of chronic wounds secondary to recessive dystrophic epidermolysis bullosa: a case series","volume":"51","author":"Sibbald","year":"2005","journal-title":"Ostomy Wound Manage"},{"issue":"5","key":"10.1016\/j.det.2010.01.008_bib14","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1902\/jop.2001.72.5.691","article-title":"Sucralfate: a help during oral management in patients with epidermolysis bullosa","volume":"72","author":"Marini","year":"2001","journal-title":"J Periodontol"},{"issue":"1\u20132","key":"10.1016\/j.det.2010.01.008_bib15","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0304-3959(98)00211-5","article-title":"Potential uses of topical opioids in palliative care\u2014report of 6 cases","volume":"80","author":"Krajnik","year":"1999","journal-title":"Pain"},{"issue":"4","key":"10.1016\/j.det.2010.01.008_bib16","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/S0885-3924(98)00140-7","article-title":"Treatment of painful skin ulcers with topical opioids","volume":"17","author":"Twillman","year":"1999","journal-title":"J Pain Symptom Manage"},{"issue":"7","key":"10.1016\/j.det.2010.01.008_bib17","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1136\/adc.2003.032003","article-title":"Peripheral opioids in inflammatory pain","volume":"89","author":"Watterson","year":"2004","journal-title":"Arch Dis Child"},{"issue":"2","key":"10.1016\/j.det.2010.01.008_bib18","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.jdermsci.2007.11.004","article-title":"The IVth international symposium on epidermolysis bullosa, Santiago, Chile, 27\u201329 September 2007","volume":"49","author":"Lucky","year":"2008","journal-title":"J Dermatol Sci"},{"issue":"3\u20134","key":"10.1016\/j.det.2010.01.008_bib19","first-page":"68","article-title":"Clinical application of amniotic membranes on a patient with epidermolysis bullosa","volume":"4","author":"Martinez Pardo","year":"1999","journal-title":"Ann Transplant"},{"issue":"4","key":"10.1016\/j.det.2010.01.008_bib20","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1542\/peds.108.4.1020","article-title":"American Academy of Pediatrics, Committee on Drugs. Acetaminophen toxicity in children","volume":"108","year":"2001","journal-title":"Pediatrics"},{"issue":"4","key":"10.1016\/j.det.2010.01.008_bib21","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1517\/14740338.6.4.341","article-title":"Acetaminophen safety and hepatotoxicity\u2014where do we go from here?","volume":"6","author":"Amar","year":"2007","journal-title":"Expert Opin Drug Saf"},{"issue":"3","key":"10.1016\/j.det.2010.01.008_bib22","first-page":"335","article-title":"The use of oral transmucosal fentanyl citrate for painful procedures in children","volume":"95","author":"Schechter","year":"1995","journal-title":"Pediatrics"},{"issue":"1","key":"10.1016\/j.det.2010.01.008_bib23","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0885-3924(96)00200-X","article-title":"Subcutaneous cannulae for morphine boluses in children: assessment of a technique","volume":"13","author":"Lamacraft","year":"1997","journal-title":"J Pain Symptom Manage"},{"issue":"2","key":"10.1016\/j.det.2010.01.008_bib24","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1089\/jpm.2006.0150","article-title":"Rational use of sublingual opioids in palliative medicine","volume":"10","author":"Reisfield","year":"2007","journal-title":"J Palliat Med"},{"issue":"2","key":"10.1016\/j.det.2010.01.008_bib25","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1007\/BF03020494","article-title":"Intranasal fentanyl provides adequate postoperative analgesia in pediatric patients","volume":"49","author":"Manjushree","year":"2002","journal-title":"Can J Anaesth"},{"issue":"4","key":"10.1016\/j.det.2010.01.008_bib26","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0885-3924(00)00180-9","article-title":"An assessment of the safety, efficacy, and acceptability of intranasal fentanyl citrate in the management of cancer-related breakthrough pain: a pilot study","volume":"20","author":"Zeppetella","year":"2000","journal-title":"J Pain Symptom Manage"},{"issue":"7","key":"10.1016\/j.det.2010.01.008_bib27","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.burns.2005.05.001","article-title":"Intranasal fentanyl is an equivalent analgesic to oral morphine in paediatric Bur patients for dressing changes: a randomised double blind crossover study","volume":"31","author":"Borland","year":"2005","journal-title":"Bur"},{"issue":"17","key":"10.1016\/j.det.2010.01.008_bib28","doi-asserted-by":"crossref","first-page":"2208","DOI":"10.1001\/jama.285.17.2208","article-title":"Management of chronic tension-type headache with tricyclic antidepressant medication, stress management therapy, and their combination: a randomized controlled trial","volume":"285","author":"Holroyd","year":"2001","journal-title":"JAMA"},{"issue":"2","key":"10.1016\/j.det.2010.01.008_bib29","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/0304-3959(95)00138-7","article-title":"Amitriptyline effectively relieves neuropathic pain following treatment of breast cancer","volume":"64","author":"Kalso","year":"1996","journal-title":"Pain"},{"issue":"12","key":"10.1016\/j.det.2010.01.008_bib30","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1016\/j.apmr.2007.07.038","article-title":"Comparison of the effectiveness of amitriptyline and gabapentin on chronic neuropathic pain in persons with spinal cord injury","volume":"88","author":"Rintala","year":"2007","journal-title":"Arch Phys Med Rehabil"},{"issue":"8","key":"10.1016\/j.det.2010.01.008_bib31","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1136\/adc.2004.068775","article-title":"Lethal cardiomyopathy in epidermolysis bullosa associated with amitriptyline","volume":"90","author":"Taibjee","year":"2005","journal-title":"Arch Dis Child"},{"issue":"4","key":"10.1016\/j.det.2010.01.008_bib32","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1007\/s10072-005-0464-z","article-title":"Oxcarbazepine is effective and safe in the treatment of neuropathic pain: pooled analysis of seven clinical studies","volume":"26","author":"Magenta","year":"2005","journal-title":"Neurol Sci"},{"issue":"9","key":"10.1016\/j.det.2010.01.008_bib33","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1046\/j.1526-4610.1999.3909633.x","article-title":"Safety of divalproex sodium in migraine prophylaxis: an open-label, long-term study. Long-term safety of depakote in headache prophylaxis study group","volume":"39","author":"Silberstein","year":"1999","journal-title":"Headache"},{"issue":"3","key":"10.1016\/j.det.2010.01.008_bib34","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD007076.pub2","article-title":"Pregabalin for acute and chronic pain in adults","author":"Moore","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"issue":"1","key":"10.1016\/j.det.2010.01.008_bib35","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1185\/030079906X158066","article-title":"Meta-analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain","volume":"23","author":"Iskedjian","year":"2007","journal-title":"Curr Med Res Opin"},{"issue":"5","key":"10.1016\/j.det.2010.01.008_bib36","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1111\/j.1365-2354.2008.00917.x","article-title":"Therapeutic use of Cannabis sativa on chemotherapy-induced nausea and vomiting among cancer patients: systematic review and meta-analysis","volume":"17","author":"Machado Rocha","year":"2008","journal-title":"Eur J Cancer Care (Engl)"},{"issue":"1","key":"10.1016\/j.det.2010.01.008_bib37","doi-asserted-by":"crossref","first-page":"245","DOI":"10.2147\/TCRM.S1928","article-title":"Cannabinoids in the management of difficult to treat pain","volume":"4","author":"Russo","year":"2008","journal-title":"Ther Clin Risk Manag"},{"issue":"3","key":"10.1016\/j.det.2010.01.008_bib38","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.pain.2008.12.003","article-title":"Ketamine for chronic non-cancer pain","volume":"141","author":"Bell","year":"2009","journal-title":"Pain"},{"issue":"3","key":"10.1016\/j.det.2010.01.008_bib39","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/S0005-7894(98)80044-0","article-title":"Role of parent-mediated pain behavior management strategies in biofeedback treatment of childhood migraines","volume":"29","author":"Allen","year":"1998","journal-title":"Behav Ther"},{"issue":"2","key":"10.1016\/j.det.2010.01.008_bib40","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1023\/A:1016295727345","article-title":"Biofeedback in the treatment of headache and other childhood pain","volume":"27","author":"Hermann","year":"2002","journal-title":"Appl Psychophysiol Biofeedback"},{"key":"10.1016\/j.det.2010.01.008_bib41","series-title":"Pain in children: a practical guide for primary care","first-page":"145","article-title":"Psychological interventions for chronic pain","author":"Kashikar-Zuck","year":"2008"},{"issue":"8","key":"10.1016\/j.det.2010.01.008_bib42","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1093\/jpepsy\/jsn029","article-title":"Chronic pain in adolescence: parental responses, adolescent coping, and their impact on adolescent's pain behaviors","volume":"33","author":"Simons","year":"2008","journal-title":"J Pediatr Psychol"},{"issue":"2","key":"10.1016\/j.det.2010.01.008_bib43","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1089\/cpb.2006.9.207","article-title":"Effectiveness of virtual reality for pediatric pain distraction during i.v. placement","volume":"9","author":"Gold","year":"2006","journal-title":"Cyberpsychol Behav"},{"issue":"1\u20132","key":"10.1016\/j.det.2010.01.008_bib44","first-page":"39","article-title":"Management of young children's acute pain and anxiety during invasive medical procedures","volume":"16","author":"Kuttner","year":"1989","journal-title":"Pediatrician"},{"issue":"4","key":"10.1016\/j.det.2010.01.008_bib45","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.jclinane.2005.11.004","article-title":"Anesthesia and pain management for pediatric patients with dystrophic epidermolysis bullosa","volume":"18","author":"Lin","year":"2006","journal-title":"J Clin Anesth"},{"issue":"8","key":"10.1016\/j.det.2010.01.008_bib46","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1111\/j.1365-4632.2007.03313.x","article-title":"Surgical management of epidermolysis bullosa: proceedings of the IInd international symposium on epidermolysis bullosa, Santiago, Chile, 2005","volume":"46","author":"Azizkhan","year":"2007","journal-title":"Int J Dermatol"},{"issue":"8","key":"10.1016\/j.det.2010.01.008_bib47","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/j.burns.2004.05.009","article-title":"Gabapentin for the treatment of itching produced by burns and wound healing in children: a pilot study","volume":"30","author":"Mendham","year":"2004","journal-title":"Burns"},{"issue":"76","key":"10.1016\/j.det.2010.01.008_bib48","first-page":"1196","article-title":"Ondansetron and pruritus in chronic liver disease: a controlled study","volume":"54","author":"Jones","year":"2007","journal-title":"Hepatogastroenterology"},{"issue":"10","key":"10.1016\/j.det.2010.01.008_bib49","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1097\/00042737-199810000-00010","article-title":"Treatment of pruritus in chronic liver disease with the 5-hydroxytryptamine receptor type 3 antagonist ondansetron: a randomized, placebo-controlled, double-blind cross-over trial","volume":"10","author":"Muller","year":"1998","journal-title":"Eur J Gastroenterol Hepatol"},{"issue":"2","key":"10.1016\/j.det.2010.01.008_bib50","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1046\/j.1365-2133.2003.05172.x","article-title":"A randomized, placebo-controlled, double-blind trial of ondansetron in renal itch","volume":"148","author":"Murphy","year":"2003","journal-title":"Br J Dermatol"},{"issue":"5","key":"10.1016\/j.det.2010.01.008_bib51","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1080\/000155502320624168","article-title":"Management of generalized pruritus in dominant dystrophic epidermolysis bullosa using low-dose oral cyclosporin","volume":"82","author":"Calikoglu","year":"2002","journal-title":"Acta Derm Venereol"},{"issue":"8","key":"10.1016\/j.det.2010.01.008_bib52","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1111\/j.1572-0241.2002.05852.x","article-title":"Preliminary observation with dronabinol in patients with intractable pruritus secondary to cholestatic liver disease","volume":"97","author":"Neff","year":"2002","journal-title":"Am J Gastroenterol"}],"container-title":["Dermatologic Clinics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0733863510000094?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0733863510000094?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,11]],"date-time":"2018-12-11T05:51:40Z","timestamp":1544507500000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0733863510000094"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4]]},"references-count":52,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,4]]}},"alternative-id":["S0733863510000094"],"URL":"https:\/\/doi.org\/10.1016\/j.det.2010.01.008","relation":{},"ISSN":["0733-8635"],"issn-type":[{"value":"0733-8635","type":"print"}],"subject":[],"published":{"date-parts":[[2010,4]]}}}