{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T07:06:32Z","timestamp":1760425592929},"reference-count":52,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","theclinics.com","derm.theclinics.com","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Dermatologic Clinics"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.det.2017.09.007","type":"journal-article","created":{"date-parts":[[2017,11,4]],"date-time":"2017-11-04T06:00:49Z","timestamp":1509775249000},"page":"49-55","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Noninvasive Body Contouring"],"prefix":"10.1016","volume":"36","author":[{"given":"Heidi","family":"Wat","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas C.","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitchel P.","family":"Goldman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.det.2017.09.007_bib1","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1002\/lsm.20719","article-title":"Selective cryolysis: a novel method of non-invasive fat removal","volume":"40","author":"Manstein","year":"2008","journal-title":"Lasers Surg Med"},{"issue":"10","key":"10.1016\/j.det.2017.09.007_bib2","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1111\/j.1524-4725.2009.01259.x","article-title":"Cryolipolysis for noninvasive fat cell destruction: initial results from a pig model","volume":"35","author":"Zelickson","year":"2009","journal-title":"Dermatol Surg"},{"issue":"3","key":"10.1016\/j.det.2017.09.007_bib3","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1177\/1090820X13520320","article-title":"Noninvasive selective cryolipolysis and reperfusion recovery for localized natural fat reduction and contouring","volume":"34","author":"Sasaki","year":"2014","journal-title":"Aesthet Surg J"},{"issue":"10","key":"10.1016\/j.det.2017.09.007_bib4","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1002\/lsm.20864","article-title":"Cryolipolysis for subcutaneous fat layer reduction","volume":"41","author":"Avram","year":"2009","journal-title":"Lasers Surg Med"},{"issue":"1","key":"10.1016\/j.det.2017.09.007_bib5","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1093\/asj\/sju024","article-title":"Cryolipolysis conformable-surface applicator for nonsurgical fat reduction in lateral thighs","volume":"35","author":"Stevens","year":"2015","journal-title":"Aesthet Surg J"},{"issue":"2","key":"10.1016\/j.det.2017.09.007_bib6","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1002\/lsm.22320","article-title":"Cryolipolysis for safe and effective inner thigh fat reduction","volume":"47","author":"Zelickson","year":"2015","journal-title":"Lasers Surg Med"},{"issue":"3","key":"10.1016\/j.det.2017.09.007_bib7","doi-asserted-by":"crossref","first-page":"126","DOI":"10.3109\/14764172.2015.1114644","article-title":"Non-invasive cryolipolysis to reduce subcutaneous fat in the arms","volume":"18","author":"Lee","year":"2016","journal-title":"J\u00a0Cosmet Laser Ther"},{"issue":"1","key":"10.1016\/j.det.2017.09.007_bib8","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/lsm.22440","article-title":"Safety and efficacy of cryolipolysis for non-invasive reduction of submental fat","volume":"48","author":"Kilmer","year":"2016","journal-title":"Lasers Surg Med"},{"issue":"5","key":"10.1016\/j.det.2017.09.007_bib9","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1001\/jamafacial.2017.0102","article-title":"Safety and efficacy of bilateral submental cryolipolysis with quantified 3-dimensional imaging of fat reduction and skin tightening","volume":"19","author":"Bernstein","year":"2017","journal-title":"JAMA Facial Plast Surg"},{"issue":"12","key":"10.1016\/j.det.2017.09.007_bib10","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1111\/jdv.12377","article-title":"Efficacy, patient-reported outcomes and safety profile of ATX-101 (deoxycholic acid), an injectable drug for the reduction of unwanted submental fat: results from a phase III, randomized, placebo-controlled study","volume":"28","author":"Ascher","year":"2014","journal-title":"J\u00a0Eur Acad Dermatol Venereol"},{"issue":"2","key":"10.1016\/j.det.2017.09.007_bib11","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1111\/bjd.12695","article-title":"Reduction of unwanted submental fat with ATX-101 (deoxycholic acid), an adipocytolytic injectable treatment: results from a phase III, randomized, placebo-controlled study","volume":"170","author":"Rzany","year":"2014","journal-title":"Br J Dermatol"},{"issue":"4","key":"10.1016\/j.det.2017.09.007_bib12","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/j.jaad.2016.04.028","article-title":"ATX-101 for reduction of submental fat: a phase III randomized controlled trial","volume":"75","author":"Humphrey","year":"2016","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"1","key":"10.1016\/j.det.2017.09.007_bib13","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1097\/DSS.0000000000000578","article-title":"REFINE-1, a multicenter, randomized, double-blind, placebo-controlled, phase 3 trial with ATX-101, an injectable drug for submental fat reduction","volume":"42","author":"Jones","year":"2016","journal-title":"Dermatol Surg"},{"issue":"Suppl 1","key":"10.1016\/j.det.2017.09.007_bib14","doi-asserted-by":"crossref","first-page":"S275","DOI":"10.1097\/DSS.0000000000000875","article-title":"Proper technique for administration of ATX-101 (deoxycholic acid injection): insights from an injection practicum and roundtable discussion","volume":"42","author":"Jones","year":"2016","journal-title":"Dermatol Surg"},{"issue":"Suppl 1","key":"10.1016\/j.det.2017.09.007_bib15","doi-asserted-by":"crossref","first-page":"S288","DOI":"10.1097\/DSS.0000000000000908","article-title":"Management of patient experience with ATX-101 (deoxycholic acid injection) for reduction of submental fat","volume":"42","author":"Dover","year":"2016","journal-title":"Dermatol Surg"},{"issue":"12","key":"10.1016\/j.det.2017.09.007_bib16","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1097\/DSS.0000000000000964","article-title":"Management of patient experience with ATX-101 (deoxycholic acid injection) for reduction of submental fat","volume":"42","author":"Humphrey","year":"2016","journal-title":"Dermatol Surg"},{"issue":"11","key":"10.1016\/j.det.2017.09.007_bib17","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1097\/DSS.0000000000000858","article-title":"A\u00a0retrospective evaluation of subsurface monopolar radiofrequency for lifting of the face, neck, and jawline","volume":"42","author":"Dendle","year":"2016","journal-title":"Dermatol Surg"},{"issue":"12","key":"10.1016\/j.det.2017.09.007_bib18","first-page":"1485","article-title":"Integration of thermal imaging with subsurface radiofrequency thermistor heating for the purpose of skin tightening and contour improvement: a retrospective review of clinical efficacy","volume":"13","author":"Key","year":"2014","journal-title":"J\u00a0Drugs Dermatol"},{"issue":"9","key":"10.1016\/j.det.2017.09.007_bib19","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1097\/DSS.0000000000000415","article-title":"Cryolipolysis for targeted fat reduction and improved appearance of the enlarged male breast","volume":"41","author":"Munavalli","year":"2015","journal-title":"Dermatol Surg"},{"issue":"2","key":"10.1016\/j.det.2017.09.007_bib20","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/lsm.21145","article-title":"Non-invasive cryolipolysis for body contouring in Chinese: a first commercial experience","volume":"44","author":"Shek","year":"2012","journal-title":"Lasers Surg Med"},{"issue":"2","key":"10.1016\/j.det.2017.09.007_bib21","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/lsm.22207","article-title":"Three-dimensional volumetric quantification of fat loss following cryolipolysis","volume":"46","author":"Garibyan","year":"2014","journal-title":"Lasers Surg Med"},{"issue":"5","key":"10.1016\/j.det.2017.09.007_bib22","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3109\/14764172.2014.946050","article-title":"Clinical effectiveness of non-invasive selective cryolipolysis","volume":"16","author":"Kim","year":"2014","journal-title":"J\u00a0Cosmet Laser Ther"},{"issue":"11","key":"10.1016\/j.det.2017.09.007_bib23","first-page":"1354","article-title":"Prospective internally controlled blind reviewed clinical evaluation of cryolipolysis combined with multipolar radiofrequency andvaripulsetechnology for enhanced subject results in circumferential fat reduction and skin laxity of the flanks","volume":"15","author":"Few","year":"2016","journal-title":"J\u00a0Drugs Dermatol"},{"issue":"4","key":"10.1016\/j.det.2017.09.007_bib24","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1002\/lsm.22475","article-title":"Cryolipolysis versus laser lipolysis on adolescent abdominal adiposity","volume":"48","author":"Mostafa","year":"2016","journal-title":"Lasers Surg Med"},{"issue":"1","key":"10.1016\/j.det.2017.09.007_bib25","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1002\/lsm.22550","article-title":"Prototype CoolCup cryolipolysis applicator with over 40% reduced treatment time demonstrates equivalent safety and efficacy with greater patient preference","volume":"49","author":"Kilmer","year":"2017","journal-title":"Lasers Surg Med"},{"issue":"1","key":"10.1016\/j.det.2017.09.007_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/DSS.0000000000000569","article-title":"Complications in the cosmetic dermatology patient: a review and our experience (part 1)","volume":"42","author":"Vanaman","year":"2016","journal-title":"Dermatol Surg"},{"issue":"1","key":"10.1016\/j.det.2017.09.007_bib27","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1097\/01.DSS.0000479796.34703.94","article-title":"Complications in the cosmetic dermatology patient: a review and our experience (part 2)","volume":"42","author":"Vanaman","year":"2016","journal-title":"Dermatol Surg"},{"issue":"11","key":"10.1016\/j.det.2017.09.007_bib28","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1097\/DSS.0000000000000502","article-title":"Delayed Onset pain associated with cryolipolysis treatment: a retrospective study with treatment recommendations","volume":"41","author":"Keaney","year":"2015","journal-title":"Dermatol Surg"},{"issue":"3","key":"10.1016\/j.det.2017.09.007_bib29","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1001\/jamadermatol.2013.8071","article-title":"Paradoxical adipose hyperplasia after cryolipolysis","volume":"150","author":"Jalian","year":"2014","journal-title":"JAMA Dermatol"},{"issue":"4","key":"10.1016\/j.det.2017.09.007_bib30","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1111\/jocd.12256","article-title":"Men at risk for paradoxical adipose hyperplasia after cryolipolysis","volume":"15","author":"Keaney","year":"2016","journal-title":"J\u00a0Cosmet Dermatol"},{"issue":"8","key":"10.1016\/j.det.2017.09.007_bib31","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1097\/DSS.0000000000001163","article-title":"Paradoxical adipose hyperplasia after cryoadipolysis refractory to tumescent liposuction","volume":"43","author":"Friedmann","year":"2017","journal-title":"Dermatol Surg"},{"issue":"6","key":"10.1016\/j.det.2017.09.007_bib32","first-page":"622","article-title":"Human adipocyte apoptosis immediately following high frequency focused field radio frequency: case study","volume":"14","author":"McDaniel","year":"2015","journal-title":"J\u00a0Drugs Dermatol"},{"key":"10.1016\/j.det.2017.09.007_bib33","doi-asserted-by":"crossref","first-page":"49","DOI":"10.12688\/f1000research.5708.1","article-title":"Non-contact radiofrequency-induced reduction of subcutaneous abdominal fat correlates with initial cardiovascular autonomic balance and fat tissue hormones: safety analysis","volume":"4","author":"Pumprla","year":"2015","journal-title":"F1000Res"},{"issue":"4","key":"10.1016\/j.det.2017.09.007_bib34","first-page":"491","article-title":"Contactless abdominal fat reduction with selective RF evaluated by magnetic resonance imaging (MRI): case study","volume":"15","author":"Downie","year":"2016","journal-title":"J\u00a0Drugs Dermatol"},{"issue":"12","key":"10.1016\/j.det.2017.09.007_bib35","first-page":"1557","article-title":"A\u00a0clinical evaluation of a next generation, non-invasive, selective radiofrequency, hands-free, body-shaping device","volume":"15","author":"Hayre","year":"2016","journal-title":"J\u00a0Drugs Dermatol"},{"issue":"12","key":"10.1016\/j.det.2017.09.007_bib36","first-page":"1422","article-title":"Evaluation of the safety and efficacy of a non-contact radiofrequency device for the improvement in contour and circumferential reduction of the inner and outer thigh","volume":"14","author":"McDaniel","year":"2015","journal-title":"J\u00a0Drugs Dermatol"},{"issue":"2","key":"10.1016\/j.det.2017.09.007_bib37","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1111\/dth.12304","article-title":"A\u00a0novel selective RF applicator for reducing thigh circumference: a clinical evaluation","volume":"29","author":"Fritz","year":"2016","journal-title":"Dermatol Ther"},{"issue":"5","key":"10.1016\/j.det.2017.09.007_bib38","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1007\/s00266-011-9700-5","article-title":"Noninvasive body sculpting technologies with an emphasis on high-intensity focused ultrasound","volume":"35","author":"Jewell","year":"2011","journal-title":"Aesthetic Plast Surg"},{"issue":"4","key":"10.1016\/j.det.2017.09.007_bib39","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1177\/1090820X11405026","article-title":"Evaluation of a novel high-intensity focused ultrasound device: preclinical studies in a porcine model","volume":"31","author":"Jewell","year":"2011","journal-title":"Aesthet Surg J"},{"issue":"4","key":"10.1016\/j.det.2017.09.007_bib40","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/lsm.20478","article-title":"Body contouring by non-invasive transdermal focused ultrasound","volume":"39","author":"Moreno-Moraga","year":"2007","journal-title":"Lasers Surg Med"},{"issue":"3","key":"10.1016\/j.det.2017.09.007_bib41","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1097\/01.prs.0000270840.98133.c8","article-title":"Noninvasive body contouring by focused ultrasound: safety and efficacy of the Contour I device in a multicenter, controlled, clinical study","volume":"120","author":"Teitelbaum","year":"2007","journal-title":"Plast Reconstr Surg"},{"issue":"1","key":"10.1016\/j.det.2017.09.007_bib42","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1097\/DSS.0000000000000918","article-title":"A\u00a0multicenter controlled study to evaluate multiple treatments with nonthermal focused ultrasound for noninvasive fat reduction","volume":"43","author":"Coleman","year":"2017","journal-title":"Dermatol Surg"},{"issue":"10","key":"10.1016\/j.det.2017.09.007_bib43","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1002\/lsm.20875","article-title":"The use of focused ultrasound for non-invasive body contouring in Asians","volume":"41","author":"Shek","year":"2009","journal-title":"Lasers Surg Med"},{"issue":"4","key":"10.1016\/j.det.2017.09.007_bib44","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.sder.2009.11.005","article-title":"High-intensity focused ultrasound effectively reduces adipose tissue","volume":"28","author":"Fatemi","year":"2009","journal-title":"Semin Cutan Med Surg"},{"issue":"5","key":"10.1016\/j.det.2017.09.007_bib45","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s00266-010-9503-0","article-title":"High-intensity focused ultrasound effectively reduces waist circumference by ablating adipose tissue from the abdomen and flanks: a retrospective case series","volume":"34","author":"Fatemi","year":"2010","journal-title":"Aesthetic Plast Surg"},{"issue":"4","key":"10.1016\/j.det.2017.09.007_bib46","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1177\/1090820X11405027","article-title":"Evaluation of a novel high-intensity focused ultrasound device for ablating subcutaneous adipose tissue for noninvasive body contouring: safety studies in human volunteers","volume":"31","author":"Gadsden","year":"2011","journal-title":"Aesthet Surg J"},{"issue":"1","key":"10.1016\/j.det.2017.09.007_bib47","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1097\/PRS.0b013e3182174278","article-title":"Randomized sham-controlled trial to evaluate the safety and effectiveness of a high-intensity focused ultrasound device for noninvasive body sculpting","volume":"128","author":"Jewell","year":"2011","journal-title":"Plast Reconstr Surg"},{"issue":"1","key":"10.1016\/j.det.2017.09.007_bib48","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1111\/j.1524-4725.2011.02148.x","article-title":"A\u00a0randomized, single-blind, postmarketing study of multiple energy levels of high-intensity focused ultrasound for noninvasive body sculpting","volume":"38","author":"Solish","year":"2012","journal-title":"Dermatol Surg"},{"issue":"6","key":"10.1016\/j.det.2017.09.007_bib49","first-page":"641","article-title":"High-intensity focused ultrasound for the reduction of subcutaneous adipose tissue using multiple treatment techniques","volume":"40","author":"Robinson","year":"2014","journal-title":"Dermatol Surg"},{"issue":"4","key":"10.1016\/j.det.2017.09.007_bib50","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1002\/lsm.22232","article-title":"Efficacy of high-intensity focused ultrasonography for noninvasive body sculpting in Chinese patients","volume":"46","author":"Shek","year":"2014","journal-title":"Lasers Surg Med"},{"issue":"5","key":"10.1016\/j.det.2017.09.007_bib51","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1111\/dsu.12123","article-title":"Safety and tolerability of a focused ultrasound device for treatment of adipose tissue in subjects undergoing abdominoplasty: a placebo-control pilot study","volume":"39","author":"Shalom","year":"2013","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.det.2017.09.007_bib52","first-page":"152","article-title":"A\u00a0pilot prospective comparative trial of high-intensity focused ultrasound versus cryolipolysis for flank subcutaneous adipose tissue and review of the literature","volume":"30","author":"Friedmann","year":"2013","journal-title":"Cosmet Dermatol"}],"container-title":["Dermatologic Clinics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0733863517301341?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0733863517301341?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,8,6]],"date-time":"2022-08-06T11:18:01Z","timestamp":1659784681000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0733863517301341"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":52,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["S0733863517301341"],"URL":"https:\/\/doi.org\/10.1016\/j.det.2017.09.007","relation":{},"ISSN":["0733-8635"],"issn-type":[{"value":"0733-8635","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Noninvasive Body Contouring","name":"articletitle","label":"Article Title"},{"value":"Dermatologic Clinics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.det.2017.09.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}