{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T10:18:06Z","timestamp":1790072286097,"version":"4.0.1"},"reference-count":67,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Dermatologic Clinics"],"published-print":{"date-parts":[[2019,4]]},"DOI":"10.1016\/j.det.2018.12.005","type":"journal-article","created":{"date-parts":[[2019,2,14]],"date-time":"2019-02-14T00:07:34Z","timestamp":1550102854000},"page":"159-168","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"title":["What's New in Melanoma"],"prefix":"10.1016","volume":"37","author":[{"given":"Giselle","family":"Prado","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan M.","family":"Svoboda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darrell S.","family":"Rigel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.det.2018.12.005_bib1","first-page":"7","article-title":"Cancer statistics, 2018","volume":"68","author":"Siegel","year":"2018","journal-title":"CA Cancer J Clin"},{"issue":"1","key":"10.1016\/j.det.2018.12.005_bib2","first-page":"7","article-title":"Cancer statistics, 2017","volume":"67","author":"Siegel","year":"2017","journal-title":"CA Cancer J Clin"},{"issue":"2","key":"10.1016\/j.det.2018.12.005_bib3","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1002\/ijc.27616","article-title":"International trends in the incidence of malignant melanoma 1953-2008\u2013are recent generations at higher or lower risk?","volume":"132","author":"Erdmann","year":"2013","journal-title":"Int J Cancer"},{"key":"10.1016\/j.det.2018.12.005_bib4","series-title":"Facts & figures 2018","year":"2018"},{"issue":"6","key":"10.1016\/j.det.2018.12.005_bib5","first-page":"1005","article-title":"Melanoma: epidemiology, risk factors, pathogenesis, diagnosis and classification","volume":"28","author":"Rastrelli","year":"2014","journal-title":"In\u00a0Vivo"},{"issue":"7424","key":"10.1016\/j.det.2018.12.005_bib6","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1038\/nature11624","article-title":"An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair\/fair skin background","volume":"491","author":"Mitra","year":"2012","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.det.2018.12.005_bib7","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1038\/jid.2013.460","article-title":"Effect of a detailed family history of melanoma on risk for other tumors: a cohort study based on the nationwide Swedish Family-Cancer Database","volume":"134","author":"Chen","year":"2014","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.det.2018.12.005_bib8","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jaad.2013.09.045","article-title":"Aspirin use and melanoma risk: a review of the literature","volume":"70","author":"Famenini","year":"2014","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"5","key":"10.1016\/j.det.2018.12.005_bib9","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/j.jaad.2017.12.076","article-title":"Postdiagnosis aspirin use and overall survival in patients with melanoma","volume":"78","author":"Rachidi","year":"2018","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"1","key":"10.1016\/j.det.2018.12.005_bib10","doi-asserted-by":"crossref","first-page":"e0147056","DOI":"10.1371\/journal.pone.0147056","article-title":"Higher caffeinated coffee intake is associated with reduced malignant melanoma risk: a meta-analysis study","volume":"11","author":"Liu","year":"2016","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.det.2018.12.005_bib11","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1007\/s00394-015-1139-z","article-title":"Coffee consumption and the risk of cutaneous melanoma: a meta-analysis","volume":"55","author":"Wang","year":"2016","journal-title":"Eur J Nutr"},{"issue":"2","key":"10.1016\/j.det.2018.12.005_bib12","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.cgh.2013.04.033","article-title":"Inflammatory bowel disease is associated with an increased risk of melanoma: a systematic review and meta-analysis","volume":"12","author":"Singh","year":"2014","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"3","key":"10.1016\/j.det.2018.12.005_bib13","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.jaad.2017.04.1129","article-title":"Phosphodiesterase type 5 inhibitors and risk of melanoma: a meta-analysis","volume":"77","author":"Tang","year":"2017","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"4","key":"10.1016\/j.det.2018.12.005_bib14","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.jaad.2015.11.014","article-title":"Risk factors and outcomes of cutaneous melanoma in women less than 50 years of age","volume":"74","author":"Tellez","year":"2016","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"3","key":"10.1016\/j.det.2018.12.005_bib15","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1038\/jid.2012.346","article-title":"Vitamin D status and skin cancer risk independent of time outdoors: 11-year prospective study in an Australian community","volume":"133","author":"Van der pols","year":"2013","journal-title":"J\u00a0Invest Dermatol"},{"issue":"2","key":"10.1016\/j.det.2018.12.005_bib16","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.jaad.2017.08.050","article-title":"Promoting sunscreen use and sun-protective practices in NCAA athletes: impact of SUNSPORT educational intervention for student-athletes, athletic trainers, and coaches","volume":"78","author":"Ally","year":"2018","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"4","key":"10.1016\/j.det.2018.12.005_bib17","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.ijwd.2017.06.002","article-title":"Promoting early detection of melanoma during the mammography experience","volume":"3","author":"Rzepecki","year":"2017","journal-title":"Int J Womens Dermatol"},{"key":"10.1016\/j.det.2018.12.005_bib18","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.ypmed.2016.04.010","article-title":"A\u00a0systematic review of interventions to improve adherence to melanoma preventive behaviors for individuals at elevated risk","volume":"88","author":"Wu","year":"2016","journal-title":"Prev Med"},{"key":"10.1016\/j.det.2018.12.005_bib19","author":"American Academy of Dermatology"},{"issue":"9","key":"10.1016\/j.det.2018.12.005_bib20","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1001\/jamadermatol.2016.1985","article-title":"Early detection of new melanomas by patients with melanoma and their partners using a structured skin self-examination skills training intervention: a randomized clinical trial","volume":"152","author":"Robinson","year":"2016","journal-title":"JAMA Dermatol"},{"issue":"3","key":"10.1016\/j.det.2018.12.005_bib21","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1200\/JCO.2010.28.7078","article-title":"Reduced melanoma after regular sunscreen use: randomized trial follow-up","volume":"29","author":"Green","year":"2011","journal-title":"J\u00a0Clin Oncol"},{"issue":"5","key":"10.1016\/j.det.2018.12.005_bib22","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1111\/1753-6405.12470","article-title":"Cancers in Australia attributable to exposure to solar ultraviolet radiation and prevented by regular sunscreen use","volume":"39","author":"Olsen","year":"2015","journal-title":"Aust N Z J Public Health"},{"issue":"5","key":"10.1016\/j.det.2018.12.005_bib23","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1016\/j.jaad.2017.12.062","article-title":"SPF 100+ sunscreen is more protective against sunburn than SPF 50+ in actual use: results of a randomized, double-blind, split-face, natural sunlight exposure clinical trial","volume":"78","author":"Williams","year":"2018","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"5","key":"10.1016\/j.det.2018.12.005_bib24","first-page":"264","article-title":"Oxybenzone and sunscreens: a critical review of the evidence and a plan for discussion with patients","volume":"2","author":"Mirsky","year":"2018","journal-title":"Skin \u2013 J Cutan Med"},{"issue":"2","key":"10.1016\/j.det.2018.12.005_bib25","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.jaad.2017.08.021","article-title":"Oral green tea catechins do not provide photoprotection from direct DNA damage induced by higher dose solar simulated radiation: a randomized controlled trial","volume":"78","author":"Farrar","year":"2018","journal-title":"J\u00a0Am Acad Dermatol"},{"key":"10.1016\/j.det.2018.12.005_bib26","doi-asserted-by":"crossref","unstructured":"Prado G, Winkelmann R, Del Rosso JQ, et\u00a0al. Clinical efficacy & safety of oral polypodium leucotomos extract for photoprotection: a systematic review. American Academy of Dermatology Annual Meeting. Washington, DC, March 2, 2019. [abstract].","DOI":"10.25251\/skin.2.6.2"},{"issue":"3","key":"10.1016\/j.det.2018.12.005_bib27","first-page":"669","article-title":"Dermoscopy compared with naked eye examination for the diagnosis of primary melanoma: a meta-analysis of studies performed in a clinical setting","volume":"159","author":"Vestergaard","year":"2008","journal-title":"Br J Dermatol"},{"issue":"5","key":"10.1016\/j.det.2018.12.005_bib28","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1111\/bjd.13121","article-title":"Clinical performance of the Nevisense system in cutaneous melanoma detection: an international, multicentre, prospective and blinded clinical trial on efficacy and safety","volume":"171","author":"Malvehy","year":"2014","journal-title":"Br J Dermatol"},{"issue":"4","key":"10.1016\/j.det.2018.12.005_bib29","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.det.2017.06.011","article-title":"High frequency ultrasound examination in the diagnosis of skin cancer","volume":"35","author":"Bard","year":"2017","journal-title":"Dermatol Clin"},{"issue":"3","key":"10.1016\/j.det.2018.12.005_bib30","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1111\/j.1600-0846.2008.00303.x","article-title":"Diagnostic image analysis of malignant melanoma in in\u00a0vivo confocal laser-scanning microscopy: a preliminary study","volume":"14","author":"Gerger","year":"2008","journal-title":"Skin Res Technol"},{"issue":"1","key":"10.1016\/j.det.2018.12.005_bib31","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.jaad.2016.07.038","article-title":"Development and validation of a noninvasive 2-gene molecular assay for cutaneous melanoma","volume":"76","author":"Gerami","year":"2017","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"5","key":"10.1016\/j.det.2018.12.005_bib32","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1097\/CMR.0000000000000478","article-title":"Real-world performance and utility of a noninvasive gene expression assay to evaluate melanoma risk in pigmented lesions","volume":"28","author":"Ferris","year":"2018","journal-title":"Melanoma Res"},{"issue":"4","key":"10.1016\/j.det.2018.12.005_bib33","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1111\/cup.12475","article-title":"Clinical validation of a gene expression signature that differentiates benign nevi from malignant melanoma","volume":"42","author":"Clarke","year":"2015","journal-title":"J\u00a0Cutan Pathol"},{"issue":"4","key":"10.1016\/j.det.2018.12.005_bib34","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1002\/cncr.30385","article-title":"An independent validation of a gene expression signature to differentiate malignant melanoma from benign melanocytic nevi","volume":"123","author":"Clarke","year":"2017","journal-title":"Cancer"},{"issue":"7","key":"10.1016\/j.det.2018.12.005_bib35","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1158\/1055-9965.EPI-16-0958","article-title":"Diagnostic distinction of malignant melanoma and benign nevi by a gene expression signature and correlation to clinical outcomes","volume":"26","author":"Ko","year":"2017","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"40","key":"10.1016\/j.det.2018.12.005_bib36","doi-asserted-by":"crossref","first-page":"e4887","DOI":"10.1097\/MD.0000000000004887","article-title":"The influence of a gene expression signature on the diagnosis and recommended treatment of melanocytic tumors by dermatopathologists","volume":"95","author":"Cockerell","year":"2016","journal-title":"Medicine (Baltimore)"},{"issue":"2","key":"10.1016\/j.det.2018.12.005_bib37","doi-asserted-by":"crossref","first-page":"123","DOI":"10.2217\/pme-2016-0097","article-title":"The influence of a gene-expression signature on the treatment of diagnostically challenging melanocytic lesions","volume":"14","author":"Cockerell","year":"2017","journal-title":"Per Med"},{"issue":"5","key":"10.1016\/j.det.2018.12.005_bib38","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/j.jaad.2017.11.019","article-title":"Racial disparities and insurance status: an epidemiological analysis of Ohio melanoma patients","volume":"78","author":"Kooistra","year":"2018","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"11","key":"10.1016\/j.det.2018.12.005_bib39","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1097\/DSS.0000000000001561","article-title":"Melanoma reporting practices of United States dermatologists","volume":"44","author":"Svoboda","year":"2018","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.det.2018.12.005_bib40","doi-asserted-by":"crossref","first-page":"S124","DOI":"10.1016\/j.jaad.2011.05.032","article-title":"Melanoma reporting to central cancer registries by US dermatologists: an analysis of the persistent knowledge and practice gap","volume":"65","author":"Cartee","year":"2011","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"4","key":"10.1016\/j.det.2018.12.005_bib41","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1245\/s10434-018-6348-2","article-title":"Predictors for use of sentinel node biopsy and the association with improved survival in melanoma patients who have nodal staging","volume":"25","author":"Murtha","year":"2018","journal-title":"Ann Surg Oncol"},{"issue":"7","key":"10.1016\/j.det.2018.12.005_bib42","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1056\/NEJMoa1310460","article-title":"Final trial report of sentinel-node biopsy versus nodal observation in melanoma","volume":"370","author":"Morton","year":"2014","journal-title":"N\u00a0Engl J Med"},{"issue":"3","key":"10.1016\/j.det.2018.12.005_bib43","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1111\/bjd.13675","article-title":"No survival benefit for patients with melanoma undergoing sentinel lymph node biopsy: critical appraisal of the Multicenter Selective Lymphadenectomy Trial-I final report","volume":"172","author":"Sladden","year":"2015","journal-title":"Br J Dermatol"},{"issue":"23","key":"10.1016\/j.det.2018.12.005_bib44","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1056\/NEJMoa1613210","article-title":"Completion dissection or observation for sentinel-node metastasis in melanoma","volume":"376","author":"Faries","year":"2017","journal-title":"N\u00a0Engl J Med"},{"issue":"1","key":"10.1016\/j.det.2018.12.005_bib45","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1186\/s13045-017-0520-1","article-title":"Interim analysis of survival in a prospective, multi-center registry cohort of cutaneous melanoma tested with a prognostic 31-gene expression profile test","volume":"10","author":"Hsueh","year":"2017","journal-title":"J\u00a0Hematol Oncol"},{"issue":"12","key":"10.1016\/j.det.2018.12.005_bib46","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1097\/DSS.0000000000001588","article-title":"Estimation of prognosis in invasive cutaneous melanoma: an independent study of the accuracy of a gene expression profile test","volume":"44","author":"Greenhaw","year":"2018","journal-title":"Dermatol Surg"},{"issue":"1","key":"10.1016\/j.det.2018.12.005_bib47","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1186\/s12885-018-4016-3","article-title":"Performance of a prognostic 31-gene expression profile in an independent cohort of 523 cutaneous melanoma patients","volume":"18","author":"Zager","year":"2018","journal-title":"BMC Cancer"},{"issue":"9","key":"10.1016\/j.det.2018.12.005_bib48","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1080\/03007995.2016.1192997","article-title":"Clinical impact of a 31-gene expression profile test for cutaneous melanoma in 156 prospectively and consecutively tested patients","volume":"32","author":"Berger","year":"2016","journal-title":"Curr Med Res Opin"},{"issue":"5","key":"10.1016\/j.det.2018.12.005_bib49","first-page":"428","article-title":"Impact of a 31-gene expression profiling test for cutaneous melanoma on dermatologists' clinical management decisions","volume":"16","author":"Farberg","year":"2017","journal-title":"J\u00a0Drugs Dermatol"},{"issue":"2","key":"10.1016\/j.det.2018.12.005_bib50","doi-asserted-by":"crossref","first-page":"111","DOI":"10.25251\/skin.2.2.3","article-title":"Prospective, multicenter clinical impact evaluation of a 31-gene expression profile test for management of melanoma patients","volume":"2","author":"Dillon","year":"2018","journal-title":"SKIN \u2013 J Cutan Med"},{"issue":"1","key":"10.1016\/j.det.2018.12.005_bib51","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.jaad.2018.07.028","article-title":"Identification of patients at risk for metastasis using a prognostic 31-gene expression profile 3 in subpopulations of melanoma patients with favorable outcomes by standard criteria","volume":"80","author":"Gastman","year":"2019","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"5","key":"10.1016\/j.det.2018.12.005_bib52","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/j.jaad.2016.11.051","article-title":"Identification of high-risk cutaneous melanoma tumors is improved when combining the online American Joint Committee on Cancer Individualized Melanoma Patient Outcome Prediction Tool with a 31-gene expression profile-based classification","volume":"76","author":"Ferris","year":"2017","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"5","key":"10.1016\/j.det.2018.12.005_bib53","first-page":"e73","article-title":"Continued elevation of a 31-gene expression profile to predict metastasis in an expanded cohort of 782 cutaneous melanoma patients","volume":"30","author":"Cook","year":"2017","journal-title":"Pigment Cell Res"},{"issue":"1","key":"10.1016\/j.det.2018.12.005_bib54","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jaad.2017.08.039","article-title":"Determination of the impact of melanoma surgical timing on survival using the National Cancer Database","volume":"78","author":"Conic","year":"2018","journal-title":"J\u00a0Am Acad Dermatol"},{"key":"10.1016\/j.det.2018.12.005_bib55","series-title":"NCCN clinical practice guidelines in Oncology. Melanoma. Version 3","year":"2018"},{"issue":"4","key":"10.1016\/j.det.2018.12.005_bib56","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1200\/JCO.2017.75.7724","article-title":"Sentinel lymph node biopsy and management of regional lymph nodes in melanoma: American Society of Clinical Oncology and Society of Surgical Oncology clinical practice guideline update","volume":"36","author":"Wong","year":"2018","journal-title":"J\u00a0Clin Oncol"},{"issue":"13","key":"10.1016\/j.det.2018.12.005_bib57","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1056\/NEJMoa060992","article-title":"Sentinel-node biopsy or nodal observation in melanoma","volume":"355","author":"Morton","year":"2006","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.det.2018.12.005_bib58","first-page":"538","article-title":"Malignant melanoma in the elderly: different regional disease and poorer prognosis","volume":"2","author":"Macdonald","year":"2011","journal-title":"J\u00a0Cancer"},{"key":"10.1016\/j.det.2018.12.005_bib59","unstructured":"Vetto JT, Monzon FA, Cook RW, et\u00a0al. Clinical utility of a 31-gene expression profile test to determine eligibility for sentinel lymph node biopsy in melanoma patients\u00a0>65 years of age. American Academy of Dermatology Annual Meeting 2018. San Diego, CA, February 16, 2018."},{"issue":"18","key":"10.1016\/j.det.2018.12.005_bib60","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1056\/NEJMoa1210093","article-title":"Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations","volume":"367","author":"Flaherty","year":"2012","journal-title":"N\u00a0Engl J Med"},{"issue":"2","key":"10.1016\/j.det.2018.12.005_bib61","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1056\/NEJMoa1302369","article-title":"Nivolumab plus ipilimumab in advanced melanoma","volume":"369","author":"Wolchok","year":"2013","journal-title":"N\u00a0Engl J Med"},{"issue":"15_suppl","key":"10.1016\/j.det.2018.12.005_bib62","doi-asserted-by":"crossref","DOI":"10.1200\/JCO.2016.34.15_suppl.3014","article-title":"Pembrolizumab (pembro) in combination with dabrafenib (D) and trametinib (T) for BRAF-mutant advanced melanoma: Phase 1 KEYNOTE-022 study","volume":"34","author":"Ribas","year":"2016","journal-title":"J\u00a0Clin Oncol"},{"issue":"8","key":"10.1016\/j.det.2018.12.005_bib63","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1056\/NEJMoa1112302","article-title":"Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib","volume":"366","author":"Sosman","year":"2012","journal-title":"N\u00a0Engl J Med"},{"issue":"26","key":"10.1016\/j.det.2018.12.005_bib64","doi-asserted-by":"crossref","first-page":"2443","DOI":"10.1056\/NEJMoa1200690","article-title":"Safety, activity, and immune correlates of anti-PD-1 antibody in cancer","volume":"366","author":"Topalian","year":"2012","journal-title":"N\u00a0Engl J Med"},{"issue":"3","key":"10.1016\/j.det.2018.12.005_bib65","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.jaad.2015.10.029","article-title":"Cutaneous adverse events (AEs) of anti-programmed cell death (PD)-1 therapy in patients with metastatic melanoma: a single-institution cohort","volume":"74","author":"Hwang","year":"2016","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"6","key":"10.1016\/j.det.2018.12.005_bib66","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1016\/j.jaad.2016.07.051","article-title":"A\u00a0comparison of current practice patterns of US dermatologists versus published guidelines for the biopsy, initial management, and follow up of patients with primary cutaneous melanoma","volume":"75","author":"Farberg","year":"2016","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"14","key":"10.1016\/j.det.2018.12.005_bib67","article-title":"Durable, long-term survival in previously treated patients with advanced melanoma (MEL) who received nivolumab (NIVO) monotherapy in a phase I trial","volume":"76","author":"Hodi","year":"2016","journal-title":"AACR"}],"container-title":["Dermatologic Clinics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0733863518311471?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0733863518311471?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T10:43:23Z","timestamp":1760006603000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0733863518311471"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":67,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["S0733863518311471"],"URL":"https:\/\/doi.org\/10.1016\/j.det.2018.12.005","relation":{},"ISSN":["0733-8635"],"issn-type":[{"value":"0733-8635","type":"print"}],"subject":[],"published":{"date-parts":[[2019,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"What's New in Melanoma","name":"articletitle","label":"Article Title"},{"value":"Dermatologic Clinics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.det.2018.12.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}