{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:53:40Z","timestamp":1787316820184,"version":"build-2736575974"},"reference-count":103,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014155","name":"Heising-Simons Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014155","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008272","name":"Novartis Pharmaceuticals Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011944","name":"School of Public Health, University of California Berkeley","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011944","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Dermatologic Clinics"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.det.2024.12.009","type":"journal-article","created":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T07:51:39Z","timestamp":1737445899000},"page":"247-260","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Hidradenitis Suppurativa Symptom Relief"],"prefix":"10.1016","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-4712-5273","authenticated-orcid":false,"given":"Anna","family":"Pulminskas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2328-5223","authenticated-orcid":false,"given":"Roxana","family":"Hojjatie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1372-2075","authenticated-orcid":false,"given":"Turkan Banu","family":"Karatas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9600-2294","authenticated-orcid":false,"given":"Yiwen H.","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0534-2854","authenticated-orcid":false,"given":"Lauren A.V.","family":"Orenstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.det.2024.12.009_bib1","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.jaad.2019.06.1301","article-title":"Evaluating patients' unmet needs in hidradenitis suppurativa: results from the global survey of impact and healthcare needs (VOICE) project","volume":"82","author":"Garg","year":"2020","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"1","key":"10.1016\/j.det.2024.12.009_bib2","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.jid.2017.09.008","article-title":"Increased suicide risk in patients with hidradenitis suppurativa","volume":"138","author":"Thorlacius","year":"2018","journal-title":"J\u00a0Invest Dermatol"},{"issue":"12","key":"10.1016\/j.det.2024.12.009_bib3","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1016\/j.jid.2018.06.171","article-title":"Women with hidradenitis suppurativa have an elevated risk of suicide","volume":"138","author":"Tiri","year":"2018","journal-title":"J\u00a0Invest Dermatol"},{"issue":"3","key":"10.1016\/j.det.2024.12.009_bib4","doi-asserted-by":"crossref","first-page":"264","DOI":"10.2340\/00015555-0866","article-title":"Psychophysical aspects of hidradenitis suppurativa","volume":"90","author":"Matusiak","year":"2010","journal-title":"Acta Derm Venereol"},{"issue":"4","key":"10.1016\/j.det.2024.12.009_bib5","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.jaad.2006.08.061","article-title":"Quality of life impairment in hidradenitis suppurativa: a study of 61 cases","volume":"56","author":"Wolkenstein","year":"2007","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"1","key":"10.1016\/j.det.2024.12.009_bib6","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1093\/bjd\/ljac018","article-title":"Pain experiences among those living with hidradenitis suppurativa: a qualitative study","volume":"188","author":"Orenstein","year":"2023","journal-title":"Br J Dermatol"},{"issue":"6","key":"10.1016\/j.det.2024.12.009_bib7","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1159\/000533740","article-title":"The influence of pain on reduced quality of life in patients with hidradenitis suppurativa: a single-center retrospective study","volume":"239","author":"Li","year":"2023","journal-title":"Dermatology"},{"issue":"13","key":"10.1016\/j.det.2024.12.009_bib8","first-page":"3813","article-title":"Itch in hidradenitis suppurativa\/acne inversa: a systematic review","volume":"11","author":"Agarwal","year":"2022","journal-title":"J\u00a0Clin Med"},{"issue":"4","key":"10.1016\/j.det.2024.12.009_bib9","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1001\/jamadermatol.2020.5857","article-title":"Expert knowledge, attitudes, and practices in management of hidradenitis suppurativa pain","volume":"157","author":"Jedrzejczak","year":"2021","journal-title":"JAMA Dermatol"},{"issue":"2","key":"10.1016\/j.det.2024.12.009_bib10","doi-asserted-by":"crossref","first-page":"191","DOI":"10.2340\/00015555-2815","article-title":"Clinical characteristics of pruritus and pain in patients with hidradenitis suppurativa","volume":"98","author":"Matusiak","year":"2018","journal-title":"Acta Derm Venereol"},{"issue":"16","key":"10.1016\/j.det.2024.12.009_bib11","first-page":"3648","article-title":"Pain as defining feature of health status and prominent therapeutic target in patients with hidradenitis suppurativa","volume":"10","author":"Sampogna","year":"2021","journal-title":"J\u00a0Clin Med"},{"issue":"4","key":"10.1016\/j.det.2024.12.009_bib12","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1111\/bjd.14266","article-title":"Self-reported pain management in hidradenitis suppurativa","volume":"174","author":"Ring","year":"2016","journal-title":"Br J Dermatol"},{"issue":"5","key":"10.1016\/j.det.2024.12.009_bib13","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1093\/bjd\/ljad215","article-title":"Healthcare experiences among patients with hidradenitis suppurativa: a qualitative study","volume":"189","author":"Sow","year":"2023","journal-title":"Br J Dermatol"},{"issue":"11","key":"10.1016\/j.det.2024.12.009_bib14","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1001\/jamadermatol.2019.2610","article-title":"Incidence of long-term opioid use among opioid-naive patients with hidradenitis suppurativa in the United States","volume":"155","author":"Reddy","year":"2019","journal-title":"JAMA Dermatol"},{"issue":"1","key":"10.1016\/j.det.2024.12.009_bib15","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1111\/bjd.18656","article-title":"Pain perception in patients with hidradenitis suppurativa","volume":"182","author":"Nielsen","year":"2020","journal-title":"Br J Dermatol"},{"issue":"12","key":"10.1016\/j.det.2024.12.009_bib16","first-page":"4046","article-title":"Prevalence of neuropathic pain and related characteristics in hidradenitis suppurativa: a cross-sectional study","volume":"9","author":"Garcovich","year":"2020","journal-title":"J\u00a0Clin Med"},{"issue":"7","key":"10.1016\/j.det.2024.12.009_bib17","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1097\/j.pain.0000000000000507","article-title":"Do we need a third mechanistic descriptor for chronic pain states?","volume":"157","author":"Kosek","year":"2016","journal-title":"Pain"},{"issue":"1","key":"10.1016\/j.det.2024.12.009_bib18","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jaad.2020.09.039","article-title":"Pain management in hidradenitis suppurativa and a proposed treatment algorithm","volume":"85","author":"Savage","year":"2021","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"6","key":"10.1016\/j.det.2024.12.009_bib19","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/s41582-024-00966-8","article-title":"Deciphering nociplastic pain: clinical features, risk factors and potential mechanisms","volume":"20","author":"Kaplan","year":"2024","journal-title":"Nat Rev Neurol"},{"issue":"1","key":"10.1016\/j.det.2024.12.009_bib20","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.jaad.2019.02.067","article-title":"North American clinical management guidelines for hidradenitis suppurativa: a publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part I: diagnosis, evaluation, and the use of complementary and procedural management","volume":"81","author":"Alikhan","year":"2019","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"1","key":"10.1016\/j.det.2024.12.009_bib21","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/jdv.15233","article-title":"Hidradenitis suppurativa\/acne inversa: a practical framework for treatment optimization - systematic review and recommendations from the HS ALLIANCE working group","volume":"33","author":"Zouboulis","year":"2019","journal-title":"J\u00a0Eur Acad Dermatol Venereol"},{"issue":"4","key":"10.1016\/j.det.2024.12.009_bib22","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1111\/jdv.12966","article-title":"European S1 guideline for the treatment of hidradenitis suppurativa\/acne inversa","volume":"29","author":"Zouboulis","year":"2015","journal-title":"J\u00a0Eur Acad Dermatol Venereol"},{"issue":"5","key":"10.1016\/j.det.2024.12.009_bib23","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1111\/bjd.17537","article-title":"British Association of Dermatologists guidelines for the management of hidradenitis suppurativa (acne inversa) 2018","volume":"180","author":"Ingram","year":"2019","journal-title":"Br J Dermatol"},{"issue":"3","key":"10.1016\/j.det.2024.12.009_bib24","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1080\/09546634.2020.1822501","article-title":"Pain management modalities for hidradenitis suppurativa: a patient survey","volume":"33","author":"Fernandez","year":"2022","journal-title":"J\u00a0Dermatolog Treat"},{"issue":"2","key":"10.1016\/j.det.2024.12.009_bib25","doi-asserted-by":"crossref","first-page":"e56","DOI":"10.1111\/ijd.15037","article-title":"Itch and pain by lesion morphology in hidradenitis suppurativa patients","volume":"60","author":"Fernandez","year":"2021","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.det.2024.12.009_bib26","series-title":"Lidocaine","author":"Beecham","year":"2024"},{"issue":"1","key":"10.1016\/j.det.2024.12.009_bib27","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1177\/0091270009336234","article-title":"Systemic bioavailability of topical diclofenac sodium gel 1% versus oral diclofenac sodium in healthy volunteers","volume":"50","author":"Kienzler","year":"2010","journal-title":"J\u00a0Clin Pharmacol"},{"issue":"2","key":"10.1016\/j.det.2024.12.009_bib28","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s40265-015-0516-5","article-title":"An update on medical treatment options for hidradenitis suppurativa","volume":"76","author":"Deckers","year":"2016","journal-title":"Drugs"},{"issue":"6","key":"10.1016\/j.det.2024.12.009_bib29","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1002\/hep.20948","article-title":"Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study","volume":"42","author":"Larson","year":"2005","journal-title":"Hepatology"},{"issue":"6","key":"10.1016\/j.det.2024.12.009_bib30","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/j.jaad.2016.06.049","article-title":"Intralesional triamcinolone for flares of hidradenitis suppurativa (HS): a case series","volume":"75","author":"Riis","year":"2016","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"5","key":"10.1016\/j.det.2024.12.009_bib31","doi-asserted-by":"crossref","first-page":"e15068","DOI":"10.1111\/dth.15068","article-title":"Ultrasound-guided injection of intralesional steroids in acute hidradenitis suppurativa lesions: a prospective study","volume":"34","author":"Iannone","year":"2021","journal-title":"Dermatol Ther"},{"issue":"2","key":"10.1016\/j.det.2024.12.009_bib32","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/ijd.15124","article-title":"Efficacy of high-dose intralesional triamcinolone for hidradenitis suppurativa","volume":"60","author":"Garelik","year":"2021","journal-title":"Int J Dermatol"},{"issue":"1","key":"10.1016\/j.det.2024.12.009_bib33","doi-asserted-by":"crossref","first-page":"13363","DOI":"10.1038\/s41598-020-70176-x","article-title":"Ultrasound-assisted intralesional corticosteroid infiltrations for patients with hidradenitis suppurativa","volume":"10","author":"Salvador-Rodriguez","year":"2020","journal-title":"Sci Rep"},{"issue":"5","key":"10.1016\/j.det.2024.12.009_bib34","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1097\/DSS.0000000000002112","article-title":"Intralesional triamcinolone may not Be beneficial for treating acute hidradenitis suppurativa lesions: a double-blind, randomized, placebo-controlled trial","volume":"46","author":"Fajgenbaum","year":"2020","journal-title":"Dermatol Surg"},{"issue":"1","key":"10.1016\/j.det.2024.12.009_bib35","first-page":"35","article-title":"Surgical management of hidradenitis suppurativa: a narrative review","volume":"15","author":"Chawla","year":"2022","journal-title":"J\u00a0Clin Aesthet Dermatol"},{"issue":"1","key":"10.1016\/j.det.2024.12.009_bib36","first-page":"13","article-title":"Surgical procedures for hidradenitis suppurativa","volume":"102","author":"Vellaichamy","year":"2018","journal-title":"Cutis"},{"issue":"3","key":"10.1016\/j.det.2024.12.009_bib37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15585\/mmwr.rr7103a1","article-title":"CDC clinical practice guideline for prescribing opioids for pain \u2014 United States","volume":"71","author":"Dowell","year":"2022","journal-title":"MMWR Recomm Rep (Morb Mortal Wkly Rep)"},{"issue":"11","key":"10.1016\/j.det.2024.12.009_bib38","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1111\/jdv.13687","article-title":"The Hidradenitis suppurativa patient journey in Italy: current status, unmet needs and opportunities","volume":"30","author":"Bettoli","year":"2016","journal-title":"J\u00a0Eur Acad Dermatol Venereol"},{"issue":"7","key":"10.1016\/j.det.2024.12.009_bib39","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/S0025-6196(11)60749-0","article-title":"A\u00a0comparison of long- and short-acting opioids for the treatment of chronic noncancer pain: tailoring therapy to meet patient needs","volume":"84","author":"Argoff","year":"2009","journal-title":"Mayo Clin Proc"},{"issue":"4","key":"10.1016\/j.det.2024.12.009_bib40","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1001\/jamainternmed.2014.8071","article-title":"Prescription opioid duration of action and the risk of unintentional overdose among patients receiving opioid therapy","volume":"175","author":"Miller","year":"2015","journal-title":"JAMA Intern Med"},{"key":"10.1016\/j.det.2024.12.009_bib41","doi-asserted-by":"crossref","first-page":"l1849","DOI":"10.1136\/bmj.l1849","article-title":"Chronic use of tramadol after acute pain episode: cohort study","volume":"365","author":"Thiels","year":"2019","journal-title":"BMJ"},{"issue":"5","key":"10.1016\/j.det.2024.12.009_bib42","first-page":"717","article-title":"The role of tramadol in current treatment strategies for musculoskeletal pain","volume":"3","author":"Schug","year":"2007","journal-title":"Ther Clin Risk Manag"},{"issue":"2","key":"10.1016\/j.det.2024.12.009_bib43","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.jaad.2021.09.058","article-title":"Wound dressings improve quality of life for hidradenitis suppurativa patients","volume":"86","author":"Schneider","year":"2022","journal-title":"J\u00a0Am Acad Dermatol"},{"key":"10.1016\/j.det.2024.12.009_bib44","first-page":"CD007938","article-title":"Gabapentin for chronic neuropathic pain and fibromyalgia in adults","volume":"3","author":"Moore","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.det.2024.12.009_bib45","series-title":"Gabapentin","author":"Yasaei","year":"2024"},{"key":"10.1016\/j.det.2024.12.009_bib46","series-title":"Pregabalin","author":"Cross","year":"2024"},{"issue":"11","key":"10.1016\/j.det.2024.12.009_bib47","doi-asserted-by":"crossref","first-page":"20616","DOI":"10.5070\/D31911020616","article-title":"Treatment of hidradenitis supprurativa associated pain with nonsteroidal anti-inflammatory drugs, acetaminophen, celecoxib, gabapentin, pegabalin, duloxetine, and venlafaxine","volume":"19","author":"Scheinfeld","year":"2013","journal-title":"Dermatol Online J"},{"issue":"12","key":"10.1016\/j.det.2024.12.009_bib48","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1016\/j.euroneuro.2017.08.430","article-title":"How addictive are gabapentin and pregabalin? A systematic review","volume":"27","author":"Bonnet","year":"2017","journal-title":"Eur Neuropsychopharmacol"},{"issue":"2","key":"10.1016\/j.det.2024.12.009_bib49","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/papr.12054","article-title":"Systematic review and meta-analysis of pharmacological therapies for painful diabetic peripheral neuropathy","volume":"14","author":"Snedecor","year":"2014","journal-title":"Pain Pract"},{"issue":"3","key":"10.1016\/j.det.2024.12.009_bib50","first-page":"32309","article-title":"A\u00a0look at commonly utilized serotonin noradrenaline reuptake inhibitors (SNRIs) in chronic pain","volume":"10","author":"Robinson","year":"2022","journal-title":"Health Psychol Res"},{"issue":"21","key":"10.1016\/j.det.2024.12.009_bib51","doi-asserted-by":"crossref","first-page":"E747","DOI":"10.1503\/cmaj.160991","article-title":"Antidepressant discontinuation syndrome","volume":"189","author":"Gabriel","year":"2017","journal-title":"CMAJ (Can Med Assoc J)"},{"issue":"3","key":"10.1016\/j.det.2024.12.009_bib52","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1002\/der2.122","article-title":"A\u00a0practical, comprehensive guide to pain management hidradenitis suppurativa","volume":"3","author":"Yiwen","year":"2022","journal-title":"Dermatological Reviews"},{"key":"10.1016\/j.det.2024.12.009_bib53","first-page":"343","article-title":"Duloxetine in the management of diabetic peripheral neuropathic pain","volume":"5","author":"Ormseth","year":"2011","journal-title":"Patient Prefer Adherence"},{"issue":"5","key":"10.1016\/j.det.2024.12.009_bib54","doi-asserted-by":"crossref","first-page":"202","DOI":"10.9740\/mhc.2015.09.202","article-title":"Antidepressants and suicidality: History, the black-box warning, consequences, and current evidence Mental","volume":"5","author":"Noel","year":"2015","journal-title":"Health Clinician"},{"issue":"1","key":"10.1016\/j.det.2024.12.009_bib55","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1213\/ANE.0000000000001683","article-title":"Trends in tramadol: pharmacology, metabolism, and misuse","volume":"124","author":"Miotto","year":"2017","journal-title":"Anesth Analg"},{"issue":"1","key":"10.1016\/j.det.2024.12.009_bib56","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/mus.20057","article-title":"Painful peripheral neuropathy and its nonsurgical treatment","volume":"30","author":"Wolfe","year":"2004","journal-title":"Muscle Nerve"},{"issue":"2\u20133","key":"10.1016\/j.det.2024.12.009_bib57","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0304-3959(96)03140-5","article-title":"A\u00a0systematic review of antidepressants in neuropathic pain","volume":"68","author":"McQuay","year":"1996","journal-title":"Pain"},{"issue":"11","key":"10.1016\/j.det.2024.12.009_bib58","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1021\/acsptsci.2c00141","article-title":"Pharmacognosy and effects of cannabinoids in the vascular system","volume":"5","author":"Mensah","year":"2022","journal-title":"ACS Pharmacol Transl Sci"},{"issue":"4","key":"10.1016\/j.det.2024.12.009_bib59","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1111\/bjd.17930","article-title":"High prevalence of cannabis use among patients with hidradenitis suppurativa: results from the VERADDICT survey","volume":"181","author":"Lesort","year":"2019","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.det.2024.12.009_bib60","doi-asserted-by":"crossref","first-page":"n1034","DOI":"10.1136\/bmj.n1034","article-title":"Medical cannabis or cannabinoids for chronic non-cancer and cancer related pain: a systematic review and meta-analysis of randomised clinical trials","volume":"374","author":"Wang","year":"2021","journal-title":"BMJ"},{"issue":"5","key":"10.1016\/j.det.2024.12.009_bib61","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/s00403-024-02878-5","article-title":"Unveiling the green connection: cannabis as a potential trigger for hidradenitis suppurativa","volume":"316","author":"Saad","year":"2024","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.det.2024.12.009_bib62","series-title":"Cognitive behavioural therapy for chronic non-cancer pain: a review of clinical effectiveness [Internet]","author":"Chao","year":"2019"},{"issue":"1","key":"10.1016\/j.det.2024.12.009_bib63","doi-asserted-by":"crossref","first-page":"e1116","DOI":"10.1097\/PR9.0000000000001116","article-title":"Empowered Relief, cognitive behavioral therapy, and health education for people with chronic pain: a comparison of outcomes at 6-month Follow-up for a randomized controlled trial","volume":"9","author":"Darnall","year":"2024","journal-title":"Pain Rep"},{"issue":"12","key":"10.1016\/j.det.2024.12.009_bib64","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1001\/jama.2016.2323","article-title":"Effect of mindfulness-based stress reduction vs cognitive behavioral therapy or usual care on back pain and functional limitations in adults with chronic low back pain: a randomized clinical trial","volume":"315","author":"Cherkin","year":"2016","journal-title":"JAMA"},{"issue":"1","key":"10.1016\/j.det.2024.12.009_bib65","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1002\/art.42672","article-title":"A\u00a0randomized controlled neuroimaging trial of cognitive behavioral therapy for fibromyalgia pain","volume":"76","author":"Lee","year":"2024","journal-title":"Arthritis Rheumatol"},{"issue":"12","key":"10.1016\/j.det.2024.12.009_bib66","doi-asserted-by":"crossref","first-page":"2782","DOI":"10.1007\/s11606-023-08140-4","article-title":"Evaluation of implementation strategies for cognitive behavioral therapy (CBT), acceptance and commitment therapy (ACT), and mindfulness-based stress reduction (MBSR): a systematic review","volume":"38","author":"Goldsmith","year":"2023","journal-title":"J\u00a0Gen Intern Med"},{"issue":"3","key":"10.1016\/j.det.2024.12.009_bib67","doi-asserted-by":"crossref","first-page":"328","DOI":"10.2340\/00015555-1082","article-title":"Psychosocial impact of hidradenitis suppurativa: a qualitative study","volume":"91","author":"Esmann","year":"2011","journal-title":"Acta Derm Venereol"},{"issue":"8","key":"10.1016\/j.det.2024.12.009_bib68","doi-asserted-by":"crossref","first-page":"757","DOI":"10.2340\/00015555-2967","article-title":"Influence of itch and pain on sleep quality in patients with hidradenitis suppurativa","volume":"98","author":"Kaaz","year":"2018","journal-title":"Acta Derm Venereol"},{"issue":"4","key":"10.1016\/j.det.2024.12.009_bib69","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1007\/s00403-019-01910-3","article-title":"Mast cells in hidradenitis suppurativa: a clinicopathological study","volume":"311","author":"List","year":"2019","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.det.2024.12.009_bib70","doi-asserted-by":"crossref","DOI":"10.1177\/2040622319851640","article-title":"TNF-alpha inhibitors in the treatment of hidradenitis suppurativa","volume":"10","author":"Savage","year":"2019","journal-title":"Ther Adv Chronic Dis"},{"issue":"5","key":"10.1016\/j.det.2024.12.009_bib71","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1016\/j.jaad.2020.05.007","article-title":"The effect of subcutaneous brodalumab on clinical disease activity in hidradenitis suppurativa: an open-label cohort study","volume":"83","author":"Frew","year":"2020","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"5\u20136","key":"10.1016\/j.det.2024.12.009_bib72","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/BF02530092","article-title":"Effect of topically applied menthol on thermal, pain and itch sensations and biophysical properties of the skin","volume":"288","author":"Yosipovitch","year":"1996","journal-title":"Arch Dermatol Res"},{"issue":"3","key":"10.1016\/j.det.2024.12.009_bib73","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/0304-3940(95)11362-Z","article-title":"Effects of menthol and cold on histamine-induced itch and skin reactions in man","volume":"187","author":"Bromm","year":"1995","journal-title":"Neurosci Lett"},{"issue":"6","key":"10.1016\/j.det.2024.12.009_bib74","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1111\/jdv.14041","article-title":"Novel TRPM8 agonist cooling compound against chronic itch: results from a randomized, double-blind, controlled, pilot study in dry skin","volume":"31","author":"Stander","year":"2017","journal-title":"J\u00a0Eur Acad Dermatol Venereol"},{"issue":"10","key":"10.1016\/j.det.2024.12.009_bib75","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1111\/bph.16012","article-title":"Lidocaine alleviates inflammation and pruritus in atopic dermatitis by blocking different population of sensory neurons","volume":"180","author":"Sun","year":"2023","journal-title":"Br J Pharmacol"},{"issue":"8","key":"10.1016\/j.det.2024.12.009_bib76","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1016\/j.jid.2022.01.002","article-title":"Lidocaine ameliorates psoriasis by obstructing pathogenic CGRP signaling\u2012mediated sensory neuron\u2012dendritic cell communication","volume":"142","author":"Yin","year":"2022","journal-title":"J\u00a0Invest Dermatol"},{"issue":"8","key":"10.1016\/j.det.2024.12.009_bib77","doi-asserted-by":"crossref","first-page":"887","DOI":"10.2217\/pmt-2022-0003","article-title":"Successful treatment of notalgia paresthetica with lidocaine 5% medicated plaster: a case report","volume":"12","author":"Correa-Illanes","year":"2022","journal-title":"Pain Manag"},{"issue":"4","key":"10.1016\/j.det.2024.12.009_bib78","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/j.jaad.2016.10.030","article-title":"Topical ketamine-amitriptyline-lidocaine for chronic pruritus: a retrospective study assessing efficacy and tolerability","volume":"76","author":"Lee","year":"2017","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"12","key":"10.1016\/j.det.2024.12.009_bib79","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1001\/jamadermatol.2016.3118","article-title":"Safety of topical neuromodulators for the treatment of pruritus","volume":"152","author":"Cardis","year":"2016","journal-title":"JAMA Dermatol"},{"issue":"2","key":"10.1016\/j.det.2024.12.009_bib80","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.sder.2011.04.008","article-title":"Topical therapies for pruritus","volume":"30","author":"Elmariah","year":"2011","journal-title":"Semin Cutan Med Surg"},{"key":"10.1016\/j.det.2024.12.009_bib81","series-title":"Statin medications","author":"Sizar","year":"2024"},{"issue":"1","key":"10.1016\/j.det.2024.12.009_bib82","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1159\/000502139","article-title":"Pruritus and malodour in patients with hidradenitis suppurativa: impact on quality of life and clinical features associated with symptom severity","volume":"236","author":"Molina-Leyva","year":"2020","journal-title":"Dermatology"},{"issue":"4","key":"10.1016\/j.det.2024.12.009_bib83","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.jaad.2016.05.027","article-title":"Multilevel symmetric neuropathic pruritus (MSNP) presenting as recalcitrant \"generalized\" pruritus","volume":"75","author":"Ward","year":"2016","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"1","key":"10.1016\/j.det.2024.12.009_bib84","first-page":"16","article-title":"Treatment of prurigo nodularis with pregabalin","volume":"38","author":"Mazza","year":"2013","journal-title":"J\u00a0Clin Pharm Therapeut"},{"issue":"8","key":"10.1016\/j.det.2024.12.009_bib85","first-page":"e17260","article-title":"The role of psychiatric, analgesic, and antiepileptic medications in chronic pruritus","volume":"13","author":"Patel","year":"2021","journal-title":"Cureus"},{"issue":"3","key":"10.1016\/j.det.2024.12.009_bib86","first-page":"73","article-title":"Mirtazapine for the treatment of chronic pruritus","volume":"6","author":"Khanna","year":"2019","journal-title":"Medicines (Basel)"},{"issue":"6","key":"10.1016\/j.det.2024.12.009_bib87","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/j.jaad.2004.01.045","article-title":"Mirtazapine for reducing nocturnal itch in patients with chronic pruritus: a pilot study","volume":"50","author":"Hundley","year":"2004","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"5","key":"10.1016\/j.det.2024.12.009_bib88","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.jaad.2016.11.021","article-title":"Psychocutaneous disease: pharmacotherapy and psychotherapy","volume":"76","author":"Kuhn","year":"2017","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"1","key":"10.1016\/j.det.2024.12.009_bib89","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.genhosppsych.2014.10.011","article-title":"Weight gain and associated factors in patients using newer antidepressant drugs","volume":"37","author":"Uguz","year":"2015","journal-title":"Gen Hosp Psychiatr"},{"issue":"3","key":"10.1016\/j.det.2024.12.009_bib90","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/ajd.12996","article-title":"Prurigo successfully treated with duloxetine hydrochloride","volume":"60","author":"Hashimoto","year":"2019","journal-title":"Australas J Dermatol"},{"issue":"1","key":"10.1016\/j.det.2024.12.009_bib91","doi-asserted-by":"crossref","first-page":"45","DOI":"10.2340\/00015555-0553","article-title":"Treatment of chronic pruritus with the selective serotonin re-uptake inhibitors paroxetine and fluvoxamine: results of an open-labelled, two-arm proof-of-concept study","volume":"89","author":"Stander","year":"2009","journal-title":"Acta Derm Venereol"},{"issue":"3","key":"10.1016\/j.det.2024.12.009_bib92","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1002\/hep.21553","article-title":"Sertraline as a first-line treatment for cholestatic pruritus","volume":"45","author":"Mayo","year":"2007","journal-title":"Hepatology"},{"issue":"14","key":"10.1016\/j.det.2024.12.009_bib93","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1056\/NEJMc0906670","article-title":"Aprepitant as an antipruritic agent?","volume":"361","author":"Duval","year":"2009","journal-title":"N\u00a0Engl J Med"},{"issue":"6","key":"10.1016\/j.det.2024.12.009_bib94","doi-asserted-by":"crossref","first-page":"e10968","DOI":"10.1371\/journal.pone.0010968","article-title":"Targeting the neurokinin receptor 1 with aprepitant: a novel antipruritic strategy","volume":"5","author":"Stander","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.det.2024.12.009_bib95","doi-asserted-by":"crossref","first-page":"4790810","DOI":"10.1155\/2017\/4790810","article-title":"Aprepitant for the treatment of chronic refractory pruritus","volume":"2017","author":"He","year":"2017","journal-title":"BioMed Res Int"},{"issue":"3","key":"10.1016\/j.det.2024.12.009_bib96","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1111\/bcp.13472","article-title":"Aprepitant and fosaprepitant decrease the effectiveness of hormonal contraceptives","volume":"84","author":"Bailard","year":"2018","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.det.2024.12.009_bib97","first-page":"155","article-title":"Perioperative administration of emend((R)) (aprepitant) at a tertiary care children's hospital: a 12-month survey","volume":"11","author":"Kanaparthi","year":"2019","journal-title":"Clin Pharmacol"},{"issue":"1","key":"10.1016\/j.det.2024.12.009_bib98","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000101940","article-title":"The effects of psychological intervention on atopic dermatitis. A systematic review and meta-analysis","volume":"144","author":"Chida","year":"2007","journal-title":"Int Arch Allergy Immunol"},{"issue":"5","key":"10.1016\/j.det.2024.12.009_bib99","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1007\/s40257-017-0280-2","article-title":"Assessing pruritus in hidradenitis suppurativa: a cross-sectional study","volume":"18","author":"Vossen","year":"2017","journal-title":"Am J Clin Dermatol"},{"issue":"2_suppl","key":"10.1016\/j.det.2024.12.009_bib100","doi-asserted-by":"crossref","first-page":"2S","DOI":"10.1177\/12034754221116115","article-title":"Practical guidelines for managing patients with hidradenitis suppurativa: an update","volume":"26","author":"Johnston","year":"2022","journal-title":"J\u00a0Cutan Med Surg"},{"issue":"1","key":"10.1016\/j.det.2024.12.009_bib101","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jaad.2019.02.068","article-title":"North American clinical management guidelines for hidradenitis suppurativa: a publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part II: topical, intralesional, and systemic medical management","volume":"81","author":"Alikhan","year":"2019","journal-title":"J\u00a0Am Acad Dermatol"},{"issue":"3","key":"10.1016\/j.det.2024.12.009_bib102","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/s11154-016-9328-5","article-title":"Evidence-based approach to the treatment of hidradenitis suppurativa\/acne inversa, based on the European guidelines for hidradenitis suppurativa","volume":"17","author":"Gulliver","year":"2016","journal-title":"Rev Endocr Metab Disord"},{"issue":"7650","key":"10.1016\/j.det.2024.12.009_bib103","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1136\/bmj.39489.470347.AD","article-title":"GRADE: an emerging consensus on rating quality of evidence and strength of recommendations","volume":"336","author":"Guyatt","year":"2008","journal-title":"BMJ"}],"container-title":["Dermatologic Clinics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0733863524001098?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0733863524001098?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T13:31:30Z","timestamp":1751376690000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0733863524001098"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":103,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["S0733863524001098"],"URL":"https:\/\/doi.org\/10.1016\/j.det.2024.12.009","relation":{},"ISSN":["0733-8635"],"issn-type":[{"value":"0733-8635","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hidradenitis Suppurativa Symptom Relief","name":"articletitle","label":"Article Title"},{"value":"Dermatologic Clinics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.det.2024.12.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}