{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T17:19:40Z","timestamp":1789751980268,"version":"4.0.1"},"reference-count":75,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,12,3]],"date-time":"2019-12-03T00:00:00Z","timestamp":1575331200000},"content-version":"vor","delay-in-days":367,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1078220"],"award-info":[{"award-number":["1078220"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"publisher","award":["BB\/I021248\/1"],"award-info":[{"award-number":["BB\/I021248\/1"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004224","name":"Peter MacCallum Cancer Centre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004224","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["090090\/Z\/09\/Z"],"award-info":[{"award-number":["090090\/Z\/09\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["GM123136"],"award-info":[{"award-number":["GM123136"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004708","name":"Kementerian Pendidikan Nasional","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004708","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1032251"],"award-info":[{"award-number":["1032251"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000048","name":"American Cancer Society","doi-asserted-by":"publisher","award":["RSG 124720"],"award-info":[{"award-number":["RSG 124720"]}],"id":[{"id":"10.13039\/100000048","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000048","name":"American Cancer Society","doi-asserted-by":"publisher","award":["ACS"],"award-info":[{"award-number":["ACS"]}],"id":[{"id":"10.13039\/100000048","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental Cell"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1016\/j.devcel.2018.09.024","type":"journal-article","created":{"date-parts":[[2018,10,25]],"date-time":"2018-10-25T13:45:51Z","timestamp":1540475151000},"page":"564-575.e5","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"title":["A Hippo-like Signaling Pathway Controls Tracheal Morphogenesis in Drosophila melanogaster"],"prefix":"10.1016","volume":"47","author":[{"given":"Carole L.C.","family":"Poon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weijie","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanjun","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Gomez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yavuz","family":"Kulaberoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaomeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjian","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexey","family":"Veraksa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Hergovich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amin","family":"Ghabrial","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kieran F.","family":"Harvey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.devcel.2018.09.024_bib1","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1016\/j.semcdb.2012.07.002","article-title":"Protein kinases of the Hippo pathway: regulation and substrates","volume":"23","author":"Avruch","year":"2012","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib2","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/1471-213X-8-55","article-title":"On the role of the MAGUK proteins encoded by Drosophila varicose during embryonic and postembryonic development","volume":"8","author":"Bachmann","year":"2008","journal-title":"BMC Dev. Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib3","doi-asserted-by":"crossref","first-page":"2279","DOI":"10.1534\/genetics.107.074088","article-title":"A clonal genetic screen for mutants causing defects in larval tracheal morphogenesis in Drosophila","volume":"176","author":"Baer","year":"2007","journal-title":"Genetics"},{"key":"10.1016\/j.devcel.2018.09.024_bib4","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1038\/35099020","article-title":"Men and sin: what\u2019s the difference?","volume":"2","author":"Bardin","year":"2001","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib5","doi-asserted-by":"crossref","first-page":"3271","DOI":"10.1242\/dev.127.15.3271","article-title":"Genetic control of epithelial tube size in the Drosophila tracheal system","volume":"127","author":"Beitel","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.devcel.2018.09.024_bib6","doi-asserted-by":"crossref","first-page":"44142","DOI":"10.18632\/oncotarget.9875","article-title":"Mitochondrial clearance by the STK38 kinase supports oncogenic Ras-induced cell transformation","volume":"7","author":"Bettoun","year":"2016","journal-title":"Oncotarget"},{"key":"10.1016\/j.devcel.2018.09.024_bib7","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1016\/j.devcel.2011.08.028","article-title":"Tao-1 phosphorylates hippo\/MST kinases to regulate the hippo-Salvador-warts tumor suppressor pathway","volume":"21","author":"Boggiano","year":"2011","journal-title":"Dev. Cell"},{"key":"10.1016\/j.devcel.2018.09.024_bib8","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/nmeth.1541","article-title":"SAINT: probabilistic scoring of affinity purification-mass spectrometry data","volume":"8","author":"Choi","year":"2011","journal-title":"Nat. Methods"},{"key":"10.1016\/j.devcel.2018.09.024_bib9","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.devcel.2016.02.004","article-title":"Drosophila Schip1 links expanded and Tao-1 to regulate hippo signaling","volume":"36","author":"Chung","year":"2016","journal-title":"Dev. Cell"},{"key":"10.1016\/j.devcel.2018.09.024_bib10","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1016\/j.cellsig.2014.04.011","article-title":"Constitutively active NDR1-PIF kinase functions independent of MST1 and hMOB1 signalling","volume":"26","author":"Cook","year":"2014","journal-title":"Cell Signal."},{"key":"10.1016\/j.devcel.2018.09.024_bib11","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1128\/MCB.01216-10","article-title":"Human NDR kinases control G(1)\/S cell cycle transition by directly regulating p21 stability","volume":"31","author":"Cornils","year":"2011","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib12","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/S0962-8924(01)01980-8","article-title":"The Ste20 group kinases as regulators of MAP kinase cascades","volume":"11","author":"Dan","year":"2001","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib13","doi-asserted-by":"crossref","first-page":"11760","DOI":"10.1074\/jbc.M211085200","article-title":"Regulation of mammalian STE20-like kinase 2 (MST2) by protein phosphorylation\/dephosphorylation and proteolysis","volume":"278","author":"Deng","year":"2003","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.devcel.2018.09.024_bib14","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/nature05954","article-title":"A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila","volume":"448","author":"Dietzl","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2018.09.024_bib15","first-page":"701","article-title":"Cerebral cavernous malformation proteins at a glance","volume":"127","author":"Draheim","year":"2014","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.devcel.2018.09.024_bib16","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.cell.2004.09.036","article-title":"Control of dendritic branching and tiling by the Tricornered-kinase\/Furry signaling pathway in Drosophila sensory neurons","volume":"119","author":"Emoto","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.devcel.2018.09.024_bib17","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1038\/nature05090","article-title":"The tumour suppressor Hippo acts with the NDR kinases in dendritic tiling and maintenance","volume":"443","author":"Emoto","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2018.09.024_bib18","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.cub.2009.11.062","article-title":"Sec24-dependent secretion drives cell-autonomous expansion of tracheal tubes in Drosophila","volume":"20","author":"F\u00f6rster","year":"2010","journal-title":"Curr. Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib19","doi-asserted-by":"crossref","first-page":"2048","DOI":"10.1242\/dev.119602","article-title":"Compensatory branching morphogenesis of stalk cells in the Drosophila trachea","volume":"142","author":"Francis","year":"2015","journal-title":"Development"},{"key":"10.1016\/j.devcel.2018.09.024_bib20","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1038\/nature05280","article-title":"A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling","volume":"444","author":"Friedman","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2018.09.024_bib21","doi-asserted-by":"crossref","first-page":"2360","DOI":"10.1242\/jcs.041806","article-title":"The Hippo pathway regulates apical-domain size independently of its growth-control function","volume":"122","author":"Genevet","year":"2009","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.devcel.2018.09.024_bib22","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.devcel.2009.12.011","article-title":"Kibra is a regulator of the Salvador\/warts\/Hippo signaling network","volume":"18","author":"Genevet","year":"2010","journal-title":"Dev. Cell"},{"key":"10.1016\/j.devcel.2018.09.024_bib23","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1093\/genetics\/156.4.1817","article-title":"The tricornered gene, which is required for the integrity of epidermal cell extensions, encodes the Drosophila nuclear DBF2-related kinase","volume":"156","author":"Geng","year":"2000","journal-title":"Genetics"},{"key":"10.1016\/j.devcel.2018.09.024_bib24","doi-asserted-by":"crossref","first-page":"e1002087","DOI":"10.1371\/journal.pgen.1002087","article-title":"A systematic screen for tube morphogenesis and branching genes in the Drosophila tracheal system","volume":"7","author":"Ghabrial","year":"2011","journal-title":"PLoS Genet."},{"key":"10.1016\/j.devcel.2018.09.024_bib25","doi-asserted-by":"crossref","first-page":"42987","DOI":"10.1074\/jbc.M208538200","article-title":"Mapping of MST1 kinase sites of phosphorylation. Activation and autophosphorylation","volume":"277","author":"Glantschnig","year":"2002","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.devcel.2018.09.024_bib26","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1083\/jcb.201207150","article-title":"Tao controls epithelial morphogenesis by promoting Fasciclin 2 endocytosis","volume":"199","author":"Gomez","year":"2012","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib27","doi-asserted-by":"crossref","first-page":"3645","DOI":"10.1242\/dev.129.15.3645","article-title":"Drumstick is a zinc finger protein that antagonizes Lines to control patterning and morphogenesis of the Drosophila hindgut","volume":"129","author":"Green","year":"2002","journal-title":"Development"},{"key":"10.1016\/j.devcel.2018.09.024_bib28","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1242\/dev.045500","article-title":"Hippo signaling: growth control and beyond","volume":"138","author":"Halder","year":"2011","journal-title":"Development"},{"key":"10.1016\/j.devcel.2018.09.024_bib29","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/S0092-8674(03)00557-9","article-title":"The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis","volume":"114","author":"Harvey","year":"2003","journal-title":"Cell"},{"key":"10.1016\/j.devcel.2018.09.024_bib30","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1038\/nrc3458","article-title":"The Hippo pathway and human cancer","volume":"13","author":"Harvey","year":"2013","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.devcel.2018.09.024_bib31","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/2045-3701-3-32","article-title":"Regulation and functions of mammalian LATS\/NDR kinases: looking beyond canonical Hippo signalling","volume":"3","author":"Hergovich","year":"2013","journal-title":"Cell Biosci"},{"key":"10.1016\/j.devcel.2018.09.024_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/genes7050021","article-title":"The roles of NDR protein kinases in hippo signalling","volume":"7","author":"Hergovich","year":"2016","journal-title":"Genes (Basel)"},{"key":"10.1016\/j.devcel.2018.09.024_bib33","doi-asserted-by":"crossref","first-page":"8259","DOI":"10.1128\/MCB.25.18.8259-8272.2005","article-title":"Human NDR kinases are rapidly activated by MOB proteins through recruitment to the plasma membrane and phosphorylation","volume":"25","author":"Hergovich","year":"2005","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib34","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1002\/biof.47","article-title":"Mammalian NDR\/LATS protein kinases in hippo tumor suppressor signaling","volume":"35","author":"Hergovich","year":"2009","journal-title":"BioFactors"},{"key":"10.1016\/j.devcel.2018.09.024_bib35","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1016\/j.semcdb.2012.04.001","article-title":"Hippo signalling in the G2\/M cell cycle phase: lessons learned from the yeast MEN and SIN pathways","volume":"23","author":"Hergovich","year":"2012","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib36","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1016\/j.cub.2009.09.020","article-title":"The MST1 and hMOB1 tumor suppressors control human centrosome duplication by regulating NDR kinase phosphorylation","volume":"19","author":"Hergovich","year":"2009","journal-title":"Curr. Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib37","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.cell.2005.06.007","article-title":"The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila homolog of YAP","volume":"122","author":"Huang","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.devcel.2018.09.024_bib38","doi-asserted-by":"crossref","first-page":"274","DOI":"10.4161\/fly.9978","article-title":"Targeted engineering of the Drosophila genome","volume":"3","author":"Huang","year":"2009","journal-title":"Fly (Austin)"},{"key":"10.1016\/j.devcel.2018.09.024_bib39","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.cell.2015.06.043","article-title":"The BioPlex network: a systematic exploration of the human interactome","volume":"162","author":"Huttlin","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.devcel.2018.09.024_bib40","doi-asserted-by":"crossref","first-page":"2514","DOI":"10.1101\/gad.1134003","article-title":"The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis","volume":"17","author":"Jia","year":"2003","journal-title":"Genes Dev."},{"key":"10.1016\/j.devcel.2018.09.024_bib41","doi-asserted-by":"crossref","first-page":"1238016","DOI":"10.1126\/science.1238016","article-title":"Opposite feedbacks in the Hippo pathway for growth control and neural fate","volume":"342","author":"Jukam","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.devcel.2018.09.024_bib42","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1523\/JNEUROSCI.4416-10.2011","article-title":"Drosophila tao controls mushroom body development and ethanol-stimulated behavior through par-1","volume":"31","author":"King","year":"2011","journal-title":"J.\u00a0Neurosci."},{"key":"10.1016\/j.devcel.2018.09.024_bib43","doi-asserted-by":"crossref","first-page":"229","DOI":"10.4161\/fly.6669","article-title":"Tandem affinity purification in Drosophila: the advantages of the GS-TAP system","volume":"2","author":"Kyriakakis","year":"2008","journal-title":"Fly (Austin)"},{"key":"10.1016\/j.devcel.2018.09.024_bib44","doi-asserted-by":"crossref","first-page":"6449","DOI":"10.1038\/ncomms7449","article-title":"CCM-3\/STRIPAK promotes seamless tube extension through endocytic recycling","volume":"6","author":"Lant","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.devcel.2018.09.024_bib45","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/S0896-6273(00)80701-1","article-title":"Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis","volume":"22","author":"Lee","year":"1999","journal-title":"Neuron"},{"key":"10.1016\/j.devcel.2018.09.024_bib46","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1242\/dev.02404","article-title":"Drosophila talin and integrin genes are required for maintenance of tracheal terminal branches and luminal organization","volume":"133","author":"Levi","year":"2006","journal-title":"Development"},{"key":"10.1016\/j.devcel.2018.09.024_bib47","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.devcel.2014.09.012","article-title":"The conserved misshapen-warts-Yorkie pathway acts in enteroblasts to regulate intestinal stem cells in Drosophila","volume":"31","author":"Li","year":"2014","journal-title":"Dev. Cell"},{"key":"10.1016\/j.devcel.2018.09.024_bib48","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.devcel.2018.04.014","article-title":"Ingestion of food particles regulates the mechanosensing misshapen-Yorkie pathway in Drosophila intestinal growth","volume":"45","author":"Li","year":"2018","journal-title":"Dev. Cell"},{"key":"10.1016\/j.devcel.2018.09.024_bib49","doi-asserted-by":"crossref","first-page":"2708","DOI":"10.1242\/jcs.068726","article-title":"Tao-1 is a negative regulator of microtubule plus-end growth","volume":"123","author":"Liu","year":"2010","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.devcel.2018.09.024_bib50","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1083\/jcb.201210073","article-title":"The Hippo pathway polarizes the actin cytoskeleton during collective migration of Drosophila border cells","volume":"201","author":"Lucas","year":"2013","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib51","doi-asserted-by":"crossref","first-page":"8357","DOI":"10.1038\/ncomms9357","article-title":"MAP4K family kinases act in parallel to MST1\/2 to activate LATS1\/2 in the Hippo pathway","volume":"6","author":"Meng","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.devcel.2018.09.024_bib52","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.ydbio.2005.02.005","article-title":"A molecular link between FGF and Dpp signaling in branch-specific migration of the Drosophila trachea","volume":"281","author":"Myat","year":"2005","journal-title":"Dev. Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib53","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.devcel.2010.09.011","article-title":"The hippo signaling pathway in development and cancer","volume":"19","author":"Pan","year":"2010","journal-title":"Dev. Cell"},{"key":"10.1016\/j.devcel.2018.09.024_bib54","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1038\/ncb1051","article-title":"The Salvador partner Hippo\u00a0promotes apoptosis and cell-cycle exit in Drosophila","volume":"5","author":"Pantalacci","year":"2003","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib55","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.devcel.2011.09.012","article-title":"The Sterile 20-like kinase Tao-1 controls tissue growth by regulating the Salvador-Warts-Hippo pathway","volume":"21","author":"Poon","year":"2011","journal-title":"Dev. Cell"},{"key":"10.1016\/j.devcel.2018.09.024_bib56","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1016\/j.cub.2016.02.009","article-title":"The\u00a0Hippo pathway regulates neuroblasts and brain size in Drosophila melanogaster","volume":"26","author":"Poon","year":"2016","journal-title":"Curr. Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib57","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1016\/j.cub.2012.06.075","article-title":"Homeodomain-interacting protein kinase regulates hippo pathway-dependent tissue growth","volume":"22","author":"Poon","year":"2012","journal-title":"Curr. Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib58","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.cub.2008.02.006","article-title":"MOBKL1A\/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation","volume":"18","author":"Praskova","year":"2008","journal-title":"Curr. Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib59","doi-asserted-by":"crossref","first-page":"e45649","DOI":"10.1371\/journal.pone.0045649","article-title":"Drosophila Zpr1 (zinc finger protein 1) is required downstream of both EGFR and FGFR signaling in tracheal subcellular lumen formation","volume":"7","author":"Ruiz","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.devcel.2018.09.024_bib60","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1242\/dev.122.5.1395","article-title":"Development of the Drosophila tracheal system occurs by a series of morphologically distinct but genetically coupled branching events","volume":"122","author":"Samakovlis","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.devcel.2018.09.024_bib61","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1046\/j.1440-169X.1996.00012.x","article-title":"A nuclear GFP\/\u03b2-galactosidase fusion protein as a marker for morphogenesis in living Drosophila","volume":"38","author":"Shiga","year":"1996","journal-title":"Dev. Growth Differ."},{"key":"10.1016\/j.devcel.2018.09.024_bib62","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.devcel.2013.05.002","article-title":"Focal defects in single-celled tubes mutant for cerebral cavernous malformation 3, GCKIII, or NSF2","volume":"25","author":"Song","year":"2013","journal-title":"Dev. Cell"},{"key":"10.1016\/j.devcel.2018.09.024_bib63","doi-asserted-by":"crossref","first-page":"11019","DOI":"10.1128\/MCB.25.24.11019-11029.2005","article-title":"Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3","volume":"25","author":"Stegert","year":"2005","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib64","doi-asserted-by":"crossref","first-page":"6710","DOI":"10.1074\/jbc.M210590200","article-title":"Mechanism of Ca2+-mediated regulation of NDR protein kinase through autophosphorylation and phosphorylation by an upstream kinase","volume":"278","author":"Tamaskovic","year":"2003","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.devcel.2018.09.024_bib65","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/S0092-8674(02)00824-3","article-title":"Salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines","volume":"110","author":"Tapon","year":"2002","journal-title":"Cell"},{"key":"10.1016\/j.devcel.2018.09.024_bib66","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1038\/ncb1050","article-title":"Hippo promotes proliferation arrest and apoptosis in the Salvador\/Warts pathway","volume":"5","author":"Udan","year":"2003","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib67","doi-asserted-by":"crossref","first-page":"10368","DOI":"10.1038\/ncomms10368","article-title":"A\u00a0Drosophila RNAi library modulates Hippo pathway-dependent tissue growth","volume":"7","author":"Vissers","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.devcel.2018.09.024_bib68","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S0092-8674(03)00549-X","article-title":"Hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with Salvador and warts","volume":"114","author":"Wu","year":"2003","journal-title":"Cell"},{"key":"10.1016\/j.devcel.2018.09.024_bib69","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/978-1-4939-6424-6_8","article-title":"Single-step affinity purification of ERK signaling complexes using the streptavidin-binding peptide (SBP) tag","volume":"1487","author":"Yang","year":"2017","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib70","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1038\/ncb793","article-title":"Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms","volume":"4","author":"Yoo","year":"2002","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib71","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.ydbio.2011.12.006","article-title":"Ccm3 functions in a manner distinct from Ccm1 and Ccm2 in a zebrafish model of CCM vascular disease","volume":"362","author":"Yoruk","year":"2012","journal-title":"Dev. Biol."},{"key":"10.1016\/j.devcel.2018.09.024_bib72","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1101\/gad.210773.112","article-title":"The Hippo pathway: regulators and regulations","volume":"27","author":"Yu","year":"2013","journal-title":"Genes Dev."},{"key":"10.1016\/j.devcel.2018.09.024_bib73","first-page":"2951","article-title":"Single-cell analysis of endothelial morphogenesis in\u00a0vivo","volume":"142","author":"Yu","year":"2015","journal-title":"Development"},{"key":"10.1016\/j.devcel.2018.09.024_bib74","first-page":"1265","article-title":"The CCM3-GCKIII partnership","volume":"28","author":"Zalvide","year":"2013","journal-title":"Histol. Histopathol."},{"key":"10.1016\/j.devcel.2018.09.024_bib75","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/j.devcel.2015.08.014","article-title":"Identification of Happyhour\/MAP4K as alternative Hpo\/Mst-like kinases in the hippo kinase cascade","volume":"34","author":"Zheng","year":"2015","journal-title":"Dev. Cell"}],"container-title":["Developmental Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1534580718308219?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1534580718308219?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T23:29:41Z","timestamp":1761521381000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1534580718308219"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":75,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["S1534580718308219"],"URL":"https:\/\/doi.org\/10.1016\/j.devcel.2018.09.024","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.734479742.793554629","asserted-by":"object"}]},"ISSN":["1534-5807"],"issn-type":[{"value":"1534-5807","type":"print"}],"subject":[],"published":{"date-parts":[[2018,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Hippo-like Signaling Pathway Controls Tracheal Morphogenesis in Drosophila melanogaster","name":"articletitle","label":"Article Title"},{"value":"Developmental Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.devcel.2018.09.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}