{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T17:23:40Z","timestamp":1790011420106,"version":"4.0.1"},"reference-count":135,"publisher":"Elsevier BV","issue":"21","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T00:00:00Z","timestamp":1730851200000},"content-version":"vor","delay-in-days":371,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["DMS2045327"],"award-info":[{"award-number":["DMS2045327"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 DK126925"],"award-info":[{"award-number":["R01 DK126925"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R35GM143019"],"award-info":[{"award-number":["R35GM143019"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental Cell"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.devcel.2023.08.010","type":"journal-article","created":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T10:29:31Z","timestamp":1693909771000},"page":"2338-2358.e5","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":55,"title":["Direct androgen receptor control of sexually dimorphic gene expression in the mammalian kidney"],"prefix":"10.1016","volume":"58","author":[{"given":"Lingyun","family":"Xiong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Yub","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kari","family":"Koppitch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Jin","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Rommelfanger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Miao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingileif B.","family":"Hallgrimsdottir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lior","family":"Pachter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhyong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam L.","family":"MacLean","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3779-1729","authenticated-orcid":false,"given":"Andrew P.","family":"McMahon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.devcel.2023.08.010_bib1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/nrneph.2017.181","article-title":"Sex and gender disparities in the epidemiology and outcomes of chronic kidney disease","volume":"14","author":"Carrero","year":"2018","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.devcel.2023.08.010_bib2","doi-asserted-by":"crossref","DOI":"10.21037\/atm.2020.03.62","article-title":"Understanding sex differences in progression and prognosis of chronic kidney disease","volume":"8","author":"Kattah","year":"2020","journal-title":"Ann. Transl. Med."},{"key":"10.1016\/j.devcel.2023.08.010_bib3","doi-asserted-by":"crossref","first-page":"1968","DOI":"10.1172\/JCI84712","article-title":"Improved renal ischemia tolerance in females influences kidney transplantation outcomes","volume":"126","author":"Aufhauser","year":"2016","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.devcel.2023.08.010_bib4","doi-asserted-by":"crossref","DOI":"10.1186\/s12882-018-1122-z","article-title":"Female sex reduces the risk of hospital-associated acute kidney injury: a meta-analysis","volume":"19","author":"Neugarten","year":"2018","journal-title":"BMC Nephrol."},{"key":"10.1016\/j.devcel.2023.08.010_bib5","doi-asserted-by":"crossref","first-page":"F149","DOI":"10.1152\/ajprenal.00099.2020","article-title":"Sex differences in renal ischemia-reperfusion injury","volume":"319","author":"Hosszu","year":"2020","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.devcel.2023.08.010_bib6","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1084\/jem.74.4.345","article-title":"Experimental nephritis in rats induced by injection of antikidney serum\u00a0: V. Chronic nephritis of insidious development following apparent recovery from acute nephrotoxic nephritis","volume":"74","author":"Smadel","year":"1941","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.devcel.2023.08.010_bib7","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1084\/jem.83.6.449","article-title":"Influence of dietary factors and sex on the toxicity of carbon tetrachloride in rats","volume":"83","author":"Gy\u00f6rgy","year":"1946","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.devcel.2023.08.010_bib8","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1002\/(SICI)1097-0185(19990701)255:3<316::AID-AR7>3.0.CO;2-5","article-title":"Sexual dimorphism of proximal straight tubular cells in mouse kidney","volume":"255","author":"Yabuki","year":"1999","journal-title":"Anat. Rec."},{"key":"10.1016\/j.devcel.2023.08.010_bib9","first-page":"445","article-title":"Effects of sex hormones on the development of giant lysosomes in the proximal tubules of DBA\/2Cr mouse kidney","volume":"202","author":"Yabuki","year":"2003","journal-title":"J.\u00a0Anat."},{"key":"10.1016\/j.devcel.2023.08.010_bib10","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1159\/000049033","article-title":"Effects of sex on renal structure","volume":"90","author":"Neugarten","year":"2002","journal-title":"Nephron"},{"key":"10.1016\/j.devcel.2023.08.010_bib11","doi-asserted-by":"crossref","first-page":"F754","DOI":"10.1152\/ajprenal.00441.2020","article-title":"Distal convoluted tubule sexual dimorphism revealed by advanced 3D imaging","volume":"319","author":"Tahaei","year":"2020","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.devcel.2023.08.010_bib12","doi-asserted-by":"crossref","first-page":"F211","DOI":"10.1152\/ajprenal.00084.2018","article-title":"Differences in renal ammonia metabolism in male and female kidney","volume":"315","author":"Harris","year":"2018","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.devcel.2023.08.010_bib13","doi-asserted-by":"crossref","first-page":"F328","DOI":"10.1152\/ajprenal.00584.2018","article-title":"Recent advances in sex differences in kidney function","volume":"316","author":"Layton","year":"2019","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.devcel.2023.08.010_bib14","doi-asserted-by":"crossref","first-page":"F505","DOI":"10.1152\/ajprenal.00087.2017","article-title":"Gender difference in kidney electrolyte transport. I. Role of AT1a receptor in thiazide-sensitive Na +-Cl \u2212 cotransporter activity and expression in male and female mice","volume":"313","author":"Li","year":"2017","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.devcel.2023.08.010_bib15","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.devcel.2004.05.005","article-title":"Major molecular differences between mammalian sexes are involved in drug metabolism and renal function","volume":"6","author":"Rinn","year":"2004","journal-title":"Dev. Cell"},{"key":"10.1016\/j.devcel.2023.08.010_bib16","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0004802","article-title":"Human and murine kidneys show gender- and species-specific gene expression differences in response to injury","volume":"4","author":"Si","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.devcel.2023.08.010_bib17","doi-asserted-by":"crossref","DOI":"10.1111\/apha.13448","article-title":"Electrolyte and transporter responses to angiotensin II induced hypertension in female and male rats and mice","volume":"229","author":"Veiras","year":"2020","journal-title":"Acta Physiol. (Oxf.)"},{"key":"10.1016\/j.devcel.2023.08.010_bib18","doi-asserted-by":"crossref","first-page":"C897","DOI":"10.1152\/ajpcell.00282.2021","article-title":"Sex-specific adaptations to high-salt diet preserve electrolyte homeostasis with distinct sodium transporter profiles","volume":"321","author":"Torres-Pinzon","year":"2021","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.devcel.2023.08.010_bib19","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.devcel.2019.10.005","article-title":"Single-cell profiling reveals sex, lineage, and regional diversity in the mouse kidney","volume":"51","author":"Ransick","year":"2019","journal-title":"Dev. Cell"},{"key":"10.1016\/j.devcel.2023.08.010_bib20","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1681\/ASN.0000000000000089","article-title":"Multiomics analyses reveal sex differences in mouse renal proximal subsegments","volume":"34","author":"Chen","year":"2023","journal-title":"J.\u00a0Am. Soc. Nephrol."},{"key":"10.1016\/j.devcel.2023.08.010_bib21","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/s41581-020-0259-8","article-title":"Sensing of tubular flow and renal electrolyte transport","volume":"16","author":"Verschuren","year":"2020","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.devcel.2023.08.010_bib22","series-title":"Brenner and Rector\u2019s the Kidney","author":"Yu","year":"2020"},{"key":"10.1016\/j.devcel.2023.08.010_bib23","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1126\/science.7403864","article-title":"Testosterone-mediated sexual dimorphism of mitochondria and lysosomes in mouse kidney proximal tubules","volume":"209","author":"Koenig","year":"1980","journal-title":"Science"},{"key":"10.1016\/j.devcel.2023.08.010_bib24","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/s00424-007-0308-1","article-title":"Gender differences in kidney function","volume":"455","author":"Saboli\u0107","year":"2007","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.devcel.2023.08.010_bib25","doi-asserted-by":"crossref","first-page":"185","DOI":"10.3390\/endocrines2030019","article-title":"Sex differences in renal function: participation of gonadal hormones and prolactin","volume":"2","author":"Franco-Acevedo","year":"2021","journal-title":"Endocrines"},{"key":"10.1016\/j.devcel.2023.08.010_bib26","doi-asserted-by":"crossref","first-page":"F452","DOI":"10.1152\/ajprenal.00188.2003","article-title":"Androgens augment proximal tubule transport","volume":"287","author":"Quan","year":"2004","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.devcel.2023.08.010_bib27","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1177\/1535370217703360","article-title":"Effects of gonadectomy and testosterone treatment on aquaporin expression in the kidney of normotensive and hypertensive rats","volume":"242","author":"Loh","year":"2017","journal-title":"Exp. Biol. Med. (Maywood)"},{"key":"10.1016\/j.devcel.2023.08.010_bib28","first-page":"778","article-title":"The action of testosterone propionate upon the kidneys of rats, dogs and men","volume":"48","author":"Lattimer","year":"1942","journal-title":"J.\u00a0Urol."},{"key":"10.1016\/j.devcel.2023.08.010_bib29","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1038\/ki.2009.522","article-title":"Testosterone increases urinary calcium excretion and inhibits expression of renal calcium transport proteins","volume":"77","author":"Hsu","year":"2010","journal-title":"Kidney Int."},{"key":"10.1016\/j.devcel.2023.08.010_bib30","doi-asserted-by":"crossref","first-page":"F922","DOI":"10.1152\/ajprenal.00560.2019","article-title":"Testosterone modulates renal ammonia metabolism","volume":"318","author":"Harris","year":"2020","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.devcel.2023.08.010_bib31","doi-asserted-by":"crossref","first-page":"F629","DOI":"10.1152\/ajprenal.00260.2021","article-title":"Role of the renal androgen receptor in sex differences in ammonia metabolism","volume":"321","author":"Harris","year":"2021","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.devcel.2023.08.010_bib32","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1111\/j.1523-1755.2005.00589.x","article-title":"Gender hormones and the progression of experimental polycystic kidney disease","volume":"68","author":"Stringer","year":"2005","journal-title":"Kidney Int."},{"key":"10.1016\/j.devcel.2023.08.010_bib33","first-page":"15","article-title":"Sex differences and the role of sex steroids in renal injury","volume":"176","author":"Metcalfe","year":"2006","journal-title":"J.\u00a0Urol."},{"key":"10.1016\/j.devcel.2023.08.010_bib34","doi-asserted-by":"crossref","first-page":"F361","DOI":"10.1152\/ajprenal.00207.2006","article-title":"Renal expression of organic anion transporter OAT2 in rats and mice is regulated by sex hormones","volume":"292","author":"Ljubojevi\u0107","year":"2007","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.devcel.2023.08.010_bib35","article-title":"Gender difference and sex hormone production in rodent renal ischemia reperfusion injury and repair","volume":"8","author":"Robert","year":"2011","journal-title":"J.\u00a0Inflamm. (Lond.)"},{"key":"10.1016\/j.devcel.2023.08.010_bib36","doi-asserted-by":"crossref","first-page":"C1174","DOI":"10.1152\/ajpcell.00450.2011","article-title":"Expression of Na+-D-glucose cotransporter SGLT2 in rodents is kidney-specific and exhibits sex and species differences","volume":"302","author":"Sabolic","year":"2012","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.devcel.2023.08.010_bib37","doi-asserted-by":"crossref","first-page":"F1114","DOI":"10.1152\/ajprenal.00201.2012","article-title":"Sex-dependent expression of Oat3 (Slc22a8) and Oat1 (Slc22a6) proteins in murine kidneys","volume":"304","author":"Breljak","year":"2013","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.devcel.2023.08.010_bib38","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1681\/ASN.2018121244","article-title":"The role of the EGF receptor in sex differences in kidney injury","volume":"30","author":"Zhang","year":"2019","journal-title":"J.\u00a0Am. Soc. Nephrol."},{"key":"10.1016\/j.devcel.2023.08.010_bib39","doi-asserted-by":"crossref","first-page":"7239","DOI":"10.1073\/pnas.94.14.7239","article-title":"Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression","volume":"94","author":"Udy","year":"1997","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"10.1016\/j.devcel.2023.08.010_bib40","doi-asserted-by":"crossref","first-page":"2613","DOI":"10.1210\/me.2006-0007","article-title":"Growth hormone regulation of sex-dependent liver gene expression","volume":"20","author":"Waxman","year":"2006","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.devcel.2023.08.010_bib41","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1210\/me.2009-0242","article-title":"Male-specific hepatic Bcl6: growth hormone-induced block of transcription elongation in females and binding to target genes inversely coordinated with STAT5","volume":"23","author":"Meyer","year":"2009","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.devcel.2023.08.010_bib42","doi-asserted-by":"crossref","first-page":"3594","DOI":"10.1128\/MCB.00280-13","article-title":"Genome-wide analysis of chromatin states reveals distinct mechanisms of sex-dependent gene regulation in male and female mouse liver","volume":"33","author":"Sugathan","year":"2013","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.devcel.2023.08.010_bib43","doi-asserted-by":"crossref","DOI":"10.1128\/MCB.00301-17","article-title":"Feminization of male mouse liver by persistent growth hormone stimulation: activation of sex-biased transcriptional networks and dynamic changes in chromatin states","volume":"37","author":"Lau-Corona","year":"2017","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.devcel.2023.08.010_bib44","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1126\/science.ade7614","article-title":"Sex matters in liver fat regulation","volume":"378","author":"Waxman","year":"2022","journal-title":"Science"},{"key":"10.1016\/j.devcel.2023.08.010_bib45","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.62585","article-title":"Proteomic and transcriptomic profiling reveal different aspects of aging in the kidney","volume":"10","author":"Takemon","year":"2021","journal-title":"ELife"},{"key":"10.1016\/j.devcel.2023.08.010_bib46","first-page":"312","article-title":"Tissue-specific pioneer factors associate with androgen receptor cistromes and transcription programs","volume":"33","author":"Pihlajamaa","year":"2014","journal-title":"EMBO J."},{"key":"10.1016\/j.devcel.2023.08.010_bib47","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-021-22266-1","article-title":"Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets","volume":"12","author":"Miao","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.devcel.2023.08.010_bib48","doi-asserted-by":"crossref","first-page":"D882","DOI":"10.1093\/nar\/gkz1062","article-title":"New developments on the Encyclopedia of DNA Elements (ENCODE) data portal","volume":"48","author":"Luo","year":"2020","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.devcel.2023.08.010_bib49","doi-asserted-by":"crossref","first-page":"W96","DOI":"10.1093\/nar\/gkq418","article-title":"ToppCluster: a multiple gene list feature analyzer for comparative enrichment clustering and network-based dissection of biological systems","volume":"38","author":"Kaimal","year":"2010","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.devcel.2023.08.010_bib50","doi-asserted-by":"crossref","DOI":"10.1038\/s41419-020-03003-w","article-title":"Understanding lipotoxicity in NAFLD pathogenesis: is CD36 a key driver?","volume":"11","author":"Rada","year":"2020","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.devcel.2023.08.010_bib51","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.molcel.2020.05.007","article-title":"Acetyl-CoA derived from hepatic peroxisomal \u03b2-oxidation inhibits autophagy and promotes steatosis via mTORC1 activation","volume":"79","author":"He","year":"2020","journal-title":"Mol. Cell"},{"key":"10.1016\/j.devcel.2023.08.010_bib52","doi-asserted-by":"crossref","DOI":"10.3390\/ijms17111868","article-title":"Stearoyl-CoA desaturase-1 protects cells against lipotoxicity-mediated apoptosis in proximal tubular cells","volume":"17","author":"Iwai","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.devcel.2023.08.010_bib53","doi-asserted-by":"crossref","first-page":"2238","DOI":"10.1194\/jlr.R056705","article-title":"Recent insights into the biological functions of liver fatty acid binding protein 1","volume":"56","author":"Wang","year":"2015","journal-title":"J.\u00a0Lipid Res."},{"key":"10.1016\/j.devcel.2023.08.010_bib54","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1128\/MCB.01548-12","article-title":"Acyl coenzyme A thioesterase 7 regulates neuronal fatty acid metabolism to prevent neurotoxicity","volume":"33","author":"Ellis","year":"2013","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.devcel.2023.08.010_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.mam.2020.100935","article-title":"Nuclear receptors in the kidney during health and disease","volume":"78","author":"Libby","year":"2021","journal-title":"Mol. Aspects Med."},{"key":"10.1016\/j.devcel.2023.08.010_bib56","doi-asserted-by":"crossref","DOI":"10.1186\/2042-6410-4-14","article-title":"Sex differences in kidney gene expression during the life cycle of F344 rats","volume":"4","author":"Kwekel","year":"2013","journal-title":"Biol. Sex Differ."},{"key":"10.1016\/j.devcel.2023.08.010_bib57","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1005896","article-title":"Clustering gene expression time series data using an infinite Gaussian process mixture model","volume":"14","author":"McDowell","year":"2018","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.devcel.2023.08.010_bib58","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1101\/gr.240663.118","article-title":"Benchmark and integration of resources for the estimation of human transcription factor activities","volume":"29","author":"Garcia-Alonso","year":"2019","journal-title":"Genome Res."},{"key":"10.1016\/j.devcel.2023.08.010_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbagrm.2019.194431","article-title":"Transfer of regulatory knowledge from human to mouse for functional genomics analysis","volume":"1863","author":"Holland","year":"2020","journal-title":"Biochim. Biophys. Acta Gene Regul. Mech."},{"key":"10.1016\/j.devcel.2023.08.010_bib60","doi-asserted-by":"crossref","first-page":"W212","DOI":"10.1093\/nar\/gkz446","article-title":"ChEA3: transcription factor enrichment analysis by orthogonal omics integration","volume":"47","author":"Keenan","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.devcel.2023.08.010_bib61","doi-asserted-by":"crossref","first-page":"2543","DOI":"10.1681\/ASN.2020020184","article-title":"Hnf4a is required for the development of Cdh6-expressing progenitors into proximal tubules in the mouse kidney","volume":"31","author":"Marable","year":"2020","journal-title":"J.\u00a0Am. Soc. Nephrol."},{"key":"10.1016\/j.devcel.2023.08.010_bib62","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1681\/ASN.2019050534","article-title":"The integrated RNA landscape of renal preconditioning against ischemia-reperfusion injury","volume":"31","author":"Johnsen","year":"2020","journal-title":"J.\u00a0Am. Soc. Nephrol."},{"key":"10.1016\/j.devcel.2023.08.010_bib63","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.stem.2008.05.020","article-title":"Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development","volume":"3","author":"Kobayashi","year":"2008","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.devcel.2023.08.010_bib64","doi-asserted-by":"crossref","first-page":"D165","DOI":"10.1093\/nar\/gkab1113","article-title":"JASPAR 2022: the 9th release of the open-access database of transcription factor binding profiles","volume":"50","author":"Castro-Mondragon","year":"2022","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.devcel.2023.08.010_bib65","doi-asserted-by":"crossref","first-page":"3180","DOI":"10.1242\/jcs.048348","article-title":"RFX3 governs growth and beating efficiency of motile cilia in mouse and controls the expression of genes involved in human ciliopathies","volume":"122","author":"El Zein","year":"2009","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.devcel.2023.08.010_bib66","doi-asserted-by":"crossref","first-page":"7567","DOI":"10.1074\/jbc.272.12.7567","article-title":"Prolactin signaling in mammary gland development","volume":"272","author":"Hennighausen","year":"1997","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.devcel.2023.08.010_bib67","doi-asserted-by":"crossref","first-page":"2585","DOI":"10.1038\/sj.onc.1203526","article-title":"The role of STAT proteins in growth hormone signaling","volume":"19","author":"Herrington","year":"2000","journal-title":"Oncogene"},{"key":"10.1016\/j.devcel.2023.08.010_bib68","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1124\/dmd.112.049429","article-title":"Characterization of four new mouse cytochrome P450 enzymes of the CYP2J subfamily","volume":"41","author":"Graves","year":"2013","journal-title":"Drug Metab. Dispos."},{"key":"10.1016\/j.devcel.2023.08.010_bib69","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1042\/bj3450115","article-title":"Molecular cloning and functional characterization of the mouse organic-anion-transporting polypeptide 1 (Oatp1) and mapping of the gene to chromosome X","volume":"345","author":"Hagenbuch","year":"2000","journal-title":"Biochem. J."},{"key":"10.1016\/j.devcel.2023.08.010_bib70","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0167-4781(01)00169-5","article-title":"Functional analysis and androgen-regulated expression of mouse organic anion transporting polypeptide 1 (Oatp1) in the kidney","volume":"1518","author":"Isern","year":"2001","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.devcel.2023.08.010_bib71","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2200582119","article-title":"Inefficient development of syncytiotrophoblasts in the Atp11a -deficient mouse placenta","volume":"119","author":"Ochiai","year":"2022","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"10.1016\/j.devcel.2023.08.010_bib72","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1016\/j.bbalip.2011.12.007","article-title":"Phospholipid flippases: building asymmetric membranes and transport vesicles","volume":"1821","author":"Sebastian","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.devcel.2023.08.010_bib73","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2016.00275","article-title":"P4-ATPases as phospholipid flippases-structure, function, and enigmas","volume":"7","author":"Andersen","year":"2016","journal-title":"Front. Physiol."},{"key":"10.1016\/j.devcel.2023.08.010_bib74","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1002\/path.4067","article-title":"Loss of glutathione S-transferase A4 accelerates obstruction-induced tubule damage and\u00a0renal fibrosis","volume":"228","author":"Liang","year":"2012","journal-title":"J.\u00a0Pathol."},{"key":"10.1016\/j.devcel.2023.08.010_bib75","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1038\/nrc2789","article-title":"ABC transporters in cancer: more than just drug efflux pumps","volume":"10","author":"Fletcher","year":"2010","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.devcel.2023.08.010_bib76","doi-asserted-by":"crossref","first-page":"23005","DOI":"10.1002\/jcp.28861","article-title":"HAO2 inhibits malignancy of clear cell renal cell carcinoma by promoting lipid catabolic process","volume":"234","author":"Xiao","year":"2019","journal-title":"J.\u00a0Cell. Physiol."},{"key":"10.1016\/j.devcel.2023.08.010_bib77","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1681\/ASN.2019040337","article-title":"Proximal tubule translational profiling during kidney fibrosis reveals proinflammatory and long noncoding RNA expression patterns with sexual dimorphism","volume":"31","author":"Wu","year":"2020","journal-title":"J.\u00a0Am. Soc. Nephrol."},{"key":"10.1016\/j.devcel.2023.08.010_bib78","doi-asserted-by":"crossref","first-page":"U95","DOI":"10.1530\/eje.0.151u095","article-title":"The regulation of GH secretion by sex steroids","volume":"151","author":"Chowen","year":"2004","journal-title":"Eur. J. Endocrinol."},{"key":"10.1016\/j.devcel.2023.08.010_bib79","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/j.1365-2265.2006.02676.x","article-title":"Modulation of growth hormone action by sex steroids","volume":"65","author":"Meinhardt","year":"2006","journal-title":"Clin. Endocrinol. (Oxf.)"},{"key":"10.1016\/j.devcel.2023.08.010_bib80","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1016\/j.cmet.2018.12.013","article-title":"Gene-by-sex interactions in mitochondrial functions and cardio-metabolic traits","volume":"29","author":"Norheim","year":"2019","journal-title":"Cell Metab."},{"key":"10.1016\/j.devcel.2023.08.010_bib81","article-title":"Distinct roles of androgen receptor, estrogen receptor alpha, and BCL6 in the establishment of sex-biased DNA methylation in mouse liver","volume":"11","author":"AlOgayil","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.devcel.2023.08.010_bib82","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1074\/jbc.274.1.305","article-title":"Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase","volume":"274","author":"Postic","year":"1999","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.devcel.2023.08.010_bib83","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.107795","article-title":"Sex differences in gene expression and regulatory networks across 29 human tissues","volume":"31","author":"Lopes-Ramos","year":"2020","journal-title":"Cell Rep."},{"key":"10.1016\/j.devcel.2023.08.010_bib84","doi-asserted-by":"crossref","DOI":"10.1126\/science.aba3066","article-title":"The impact of sex on gene expression across human tissues","volume":"369","author":"Oliva","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.devcel.2023.08.010_bib85","doi-asserted-by":"crossref","DOI":"10.1016\/j.gene.2020.144790","article-title":"Single-cell profiling reveals sex diversity in human renal proximal tubules","volume":"752","author":"Huang","year":"2020","journal-title":"Gene"},{"key":"10.1016\/j.devcel.2023.08.010_bib86","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-021-22368-w","article-title":"Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney","volume":"12","author":"Muto","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.devcel.2023.08.010_bib87","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.amjms.2019.11.004","article-title":"Renal lipid metabolism and lipotoxicity in diabetes","volume":"359","author":"Thongnak","year":"2020","journal-title":"Am. J. Med. Sci."},{"key":"10.1016\/j.devcel.2023.08.010_bib88","article-title":"Metabolic interplay between peroxisomes and other subcellular organelles including mitochondria and the endoplasmic reticulum","volume":"3","author":"Wanders","year":"2015","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.devcel.2023.08.010_bib89","doi-asserted-by":"crossref","first-page":"F1117","DOI":"10.1152\/ajprenal.00320.2020","article-title":"Sex differences in renal mitochondrial function: a hormone-Gous opportunity for research","volume":"319","author":"Sultanova","year":"2020","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.devcel.2023.08.010_bib90","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1194\/jlr.M074427","article-title":"Kidney triglyceride accumulation in the fasted mouse is dependent upon serum free fatty acids","volume":"58","author":"Scerbo","year":"2017","journal-title":"J.\u00a0Lipid Res."},{"key":"10.1016\/j.devcel.2023.08.010_bib91","doi-asserted-by":"crossref","DOI":"10.3390\/cells9061342","article-title":"Reactive oxygen species and redox signaling in chronic kidney disease","volume":"9","author":"Irazabal","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.devcel.2023.08.010_bib92","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1146\/annurev-pharmtox-011112-140320","article-title":"Role of nrf2 in oxidative stress and toxicity","volume":"53","author":"Ma","year":"2013","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.devcel.2023.08.010_bib93","doi-asserted-by":"crossref","DOI":"10.3390\/molecules25225474","article-title":"An overview of Nrf2 signaling pathway and its role in inflammation","volume":"25","author":"Saha","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.devcel.2023.08.010_bib94","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.111610","article-title":"Sex differences in resilience to ferroptosis underlie sexual dimorphism in kidney injury and repair","volume":"41","author":"Ide","year":"2022","journal-title":"Cell Rep."},{"key":"10.1016\/j.devcel.2023.08.010_bib95","first-page":"1011","article-title":"Ciliogenesis is reciprocally regulated by PPARA and NR1H4\/FXR through controlling autophagy in\u00a0vitro and in\u00a0vivo","volume":"14","author":"Liu","year":"2018","journal-title":"Autophagy"},{"key":"10.1016\/j.devcel.2023.08.010_bib96","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1016\/j.cmet.2022.10.008","article-title":"Mitochondrial signal transduction","volume":"34","author":"Picard","year":"2022","journal-title":"Cell Metab."},{"key":"10.1016\/j.devcel.2023.08.010_bib97","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1111\/j.1474-9726.2006.00236.x","article-title":"Does caloric restriction extend life in wild mice?","volume":"5","author":"Harper","year":"2006","journal-title":"Aging Cell"},{"key":"10.1016\/j.devcel.2023.08.010_bib98","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1111\/j.1474-9726.2010.00553.x","article-title":"Long-term effects of calorie restriction on serum sex-hormone concentrations in men","volume":"9","author":"Cangemi","year":"2010","journal-title":"Aging Cell"},{"key":"10.1016\/j.devcel.2023.08.010_bib99","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1128\/MCB.06312-11","article-title":"Dynamic, sex-differential STAT5 and BCL6 binding to sex-biased, growth hormone-regulated genes in adult mouse liver","volume":"32","author":"Zhang","year":"2012","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.devcel.2023.08.010_bib100","doi-asserted-by":"crossref","DOI":"10.1210\/endocr\/bqac046","article-title":"Constitutively active STAT5b feminizes mouse liver gene expression","volume":"163","author":"Lau-Corona","year":"2022","journal-title":"Endocrinology"},{"key":"10.1016\/j.devcel.2023.08.010_bib101","doi-asserted-by":"crossref","first-page":"3915","DOI":"10.1016\/S0021-9258(19)50613-5","article-title":"Sex-dependent expression and clofibrate inducibility of cytochrome P450 4A fatty acid omega-hydroxylases. Male specificity of liver and kidney CYP4A2 mRNA and tissue-specific regulation by growth hormone and testosterone","volume":"267","author":"Sundseth","year":"1992","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.devcel.2023.08.010_bib102","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1126\/science.1195262","article-title":"Temperature as a universal resetting cue for mammalian circadian oscillators","volume":"330","author":"Buhr","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.devcel.2023.08.010_bib103","doi-asserted-by":"crossref","first-page":"3284","DOI":"10.1210\/jcem.86.7.7644","article-title":"Synchronicity of frequently sampled thyrotropin (TSH) and leptin concentrations in healthy adults and leptin-deficient subjects: evidence for possible partial TSH regulation by leptin in humans","volume":"86","author":"Mantzoros","year":"2001","journal-title":"J.\u00a0Clin. Endocrinol. Metab."},{"key":"10.1016\/j.devcel.2023.08.010_bib104","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1002\/j.2040-4603.2012.tb00441.x","article-title":"Biophysics of glomerular filtration","volume":"2","author":"Thomson","year":"2012","journal-title":"Compr. Physiol."},{"key":"10.1016\/j.devcel.2023.08.010_bib105","doi-asserted-by":"crossref","first-page":"3629","DOI":"10.1016\/j.cub.2021.05.057","article-title":"Molecular evidence for a single origin of ultrafiltration-based excretory organs","volume":"31","author":"G\u0105siorowski","year":"2021","journal-title":"Curr. Biol."},{"key":"10.1016\/j.devcel.2023.08.010_bib106","doi-asserted-by":"crossref","first-page":"F769","DOI":"10.1152\/ajprenal.00484.2018","article-title":"The nephron-arterial network and its interactions","volume":"316","author":"Marsh","year":"2019","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.devcel.2023.08.010_bib107","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-022-32972-z","article-title":"Multimodal single cell sequencing implicates chromatin accessibility and genetic background in diabetic kidney disease progression","volume":"13","author":"Wilson","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.devcel.2023.08.010_bib108","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-022-35297-z","article-title":"Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunity","volume":"13","author":"McEvoy","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.devcel.2023.08.010_bib109","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1681\/ASN.2022010076","article-title":"HNF1B alters\u00a0an evolutionarily conserved nephrogenic program of target genes","volume":"34","author":"Grand","year":"2023","journal-title":"J.\u00a0Am. Soc. Nephrol."},{"key":"10.1016\/j.devcel.2023.08.010_bib110","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.kint.2022.07.027","article-title":"A comparative study of cellular diversity between the Xenopus pronephric and mouse metanephric nephron","volume":"103","author":"Corkins","year":"2023","journal-title":"Kidney Int."},{"key":"10.1016\/j.devcel.2023.08.010_bib111","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-17204-5","article-title":"QuPath: open source software for digital pathology image analysis","volume":"7","author":"Bankhead","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.devcel.2023.08.010_bib112","doi-asserted-by":"crossref","first-page":"i884","DOI":"10.1093\/bioinformatics\/bty560","article-title":"fastp: an ultra-fast all-in-one FASTQ preprocessor","volume":"34","author":"Chen","year":"2018","journal-title":"Bioinformatics"},{"key":"10.1016\/j.devcel.2023.08.010_bib113","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","article-title":"STAR: ultrafast universal RNA-seq aligner","volume":"29","author":"Dobin","year":"2013","journal-title":"Bioinformatics"},{"key":"10.1016\/j.devcel.2023.08.010_bib114","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1093\/bioinformatics\/btt656","article-title":"featureCounts: an efficient general\u00a0purpose program for assigning sequence reads to genomic features","volume":"30","author":"Liao","year":"2014","journal-title":"Bioinformatics"},{"key":"10.1016\/j.devcel.2023.08.010_bib115","doi-asserted-by":"crossref","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.devcel.2023.08.010_bib116","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1038\/nmeth.4324","article-title":"Differential analysis of RNA-seq incorporating quantification uncertainty","volume":"14","author":"Pimentel","year":"2017","journal-title":"Nat. Methods"},{"key":"10.1016\/j.devcel.2023.08.010_bib117","doi-asserted-by":"crossref","first-page":"5048","DOI":"10.1093\/bioinformatics\/btz438","article-title":"PSI-Sigma: a comprehensive splicing-detection method for short-read and long-read RNA-seq analysis","volume":"35","author":"Lin","year":"2019","journal-title":"Bioinformatics"},{"key":"10.1016\/j.devcel.2023.08.010_bib118","doi-asserted-by":"crossref","DOI":"10.12688\/f1000research.15398.1","article-title":"Swimming downstream: statistical analysis of differential transcript usage following Salmon quantification","volume":"7","author":"Love","year":"2018","journal-title":"F1000Res"},{"key":"10.1016\/j.devcel.2023.08.010_bib119","doi-asserted-by":"crossref","first-page":"3573","DOI":"10.1016\/j.cell.2021.04.048","article-title":"Integrated analysis of multimodal single-cell data","volume":"184","author":"Hao","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.devcel.2023.08.010_bib120","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1038\/s41592-021-01282-5","article-title":"Single-cell chromatin state analysis with Signac","volume":"18","author":"Stuart","year":"2021","journal-title":"Nat. Methods"},{"key":"10.1016\/j.devcel.2023.08.010_bib121","doi-asserted-by":"crossref","DOI":"10.1093\/gigascience\/giaa151","article-title":"SoupX removes ambient RNA contamination from droplet-based single-cell RNA sequencing data","volume":"9","author":"Young","year":"2020","journal-title":"Gigascience"},{"key":"10.1016\/j.devcel.2023.08.010_bib122","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.cels.2019.03.003","article-title":"DoubletFinder: doublet detection in single-cell RNA sequencing data using artificial nearest neighbors","volume":"8","author":"McGinnis","year":"2019","journal-title":"Cell Syst."},{"key":"10.1016\/j.devcel.2023.08.010_bib123","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1038\/s41588-021-00790-6","article-title":"ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis","volume":"53","author":"Granja","year":"2021","journal-title":"Nat. Genet."},{"key":"10.1016\/j.devcel.2023.08.010_bib124","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2008-9-9-r137","article-title":"Model-based analysis of ChIP-seq (MACS)","volume":"9","author":"Zhang","year":"2008","journal-title":"Genome Biol."},{"key":"10.1016\/j.devcel.2023.08.010_bib125","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1093\/bioinformatics\/btt143","article-title":"Shrinkage estimation of dispersion in Negative Binomial models for RNA-seq experiments with small sample size","volume":"29","author":"Yu","year":"2013","journal-title":"Bioinformatics"},{"key":"10.1016\/j.devcel.2023.08.010_bib126","doi-asserted-by":"crossref","first-page":"W39","DOI":"10.1093\/nar\/gkv416","article-title":"The MEME Suite","volume":"43","author":"Bailey","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.devcel.2023.08.010_bib127","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.1923","article-title":"Fast gapped-read alignment with Bowtie 2","volume":"9","author":"Langmead","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1016\/j.devcel.2023.08.010_bib128","doi-asserted-by":"crossref","DOI":"10.1093\/gigascience\/giab008","article-title":"Twelve years of SAMtools and BCFtools","volume":"10","author":"Danecek","year":"2021","journal-title":"Gigascience"},{"key":"10.1016\/j.devcel.2023.08.010_bib129","doi-asserted-by":"crossref","first-page":"2204","DOI":"10.1093\/bioinformatics\/btq351","article-title":"BigWig and BigBed: enabling browsing of large distributed datasets","volume":"26","author":"Kent","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.devcel.2023.08.010_bib130","doi-asserted-by":"crossref","first-page":"19619","DOI":"10.1073\/pnas.1908706116","article-title":"The single-cell transcriptomic landscape of early human diabetic nephropathy","volume":"116","author":"Wilson","year":"2019","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"10.1016\/j.devcel.2023.08.010_bib131","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2010-11-3-r25","article-title":"A scaling normalization method for differential expression analysis of RNA-seq data","volume":"11","author":"Robinson","year":"2010","journal-title":"Genome Biol."},{"key":"10.1016\/j.devcel.2023.08.010_bib132","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-28948-z","article-title":"GOATOOLS: a Python library for Gene Ontology analyses","volume":"8","author":"Klopfenstein","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.devcel.2023.08.010_bib133","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2026684118","article-title":"Single-nuclear transcriptomics reveals diversity of proximal tubule cell states in a dynamic response to acute kidney injury","volume":"118","author":"Gerhardt","year":"2021","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"10.1016\/j.devcel.2023.08.010_bib134","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1038\/s41586-021-04262-z","article-title":"Decoding gene regulation in the fly brain","volume":"601","author":"Janssens","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2023.08.010_bib135","doi-asserted-by":"crossref","first-page":"D252","DOI":"10.1093\/nar\/gkx1106","article-title":"HOCOMOCO: towards a complete collection of transcription factor binding models for human and mouse via large-scale ChIP-Seq analysis","volume":"46","author":"Kulakovskiy","year":"2018","journal-title":"Nucleic Acids Res."}],"container-title":["Developmental Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1534580723004069?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1534580723004069?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T20:20:58Z","timestamp":1778617258000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1534580723004069"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":135,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["S1534580723004069"],"URL":"https:\/\/doi.org\/10.1016\/j.devcel.2023.08.010","relation":{},"ISSN":["1534-5807"],"issn-type":[{"value":"1534-5807","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Direct androgen receptor control of sexually dimorphic gene expression in the mammalian kidney","name":"articletitle","label":"Article Title"},{"value":"Developmental Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.devcel.2023.08.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}