{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T22:14:22Z","timestamp":1772576062029,"version":"3.50.1"},"reference-count":89,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,12]],"date-time":"2024-03-12T00:00:00Z","timestamp":1710201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental Cell"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.devcel.2024.03.007","type":"journal-article","created":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T14:42:44Z","timestamp":1712241764000},"page":"1439-1456.e7","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Oct4 controls basement membrane development during human embryogenesis"],"prefix":"10.1016","volume":"59","author":[{"given":"Margit","family":"Rosner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Hengstschl\u00e4ger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.devcel.2024.03.007_bib1","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/d41586-018-07663-9","article-title":"Debate ethics of embryo models from stem cells","volume":"564","author":"Rivron","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2024.03.007_bib2","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1083\/jcb.201810084","article-title":"Opening the black box: stem cell-based modeling of human post-implantation development","volume":"218","author":"Taniguchi","year":"2019","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.devcel.2024.03.007_bib3","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1093\/humupd\/dmaa027","article-title":"Modelling human embryogenesis: embryo-like structures spark ethical and policy debate","volume":"26","author":"Pereira Daoud","year":"2020","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.devcel.2024.03.007_bib4","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/nature17948","article-title":"Self-organization of the in\u00a0vitro attached human embryo","volume":"533","author":"Deglincerti","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2024.03.007_bib5","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1038\/ncb3347","article-title":"Self-organization of the human embryo in the absence of maternal tissues","volume":"18","author":"Shahbazi","year":"2016","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.devcel.2024.03.007_bib6","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1038\/s41586-019-1500-0","article-title":"Reconstituting the transcriptome and DNA methylome landscapes of human implantation","volume":"572","author":"Zhou","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2024.03.007_bib7","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1038\/s41586-019-1875-y","article-title":"A developmental landscape of 3D-cultured human pre-gastrulation embryos","volume":"577","author":"Xiang","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2024.03.007_bib8","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1038\/533169a","article-title":"Embryology policy: revisit the 14-day rule","volume":"533","author":"Hyun","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2024.03.007_bib9","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.devcel.2019.02.024","article-title":"Understanding the mechanobiology of early mammalian development through bioengineered models","volume":"48","author":"Vianello","year":"2019","journal-title":"Dev. Cell"},{"key":"10.1016\/j.devcel.2024.03.007_bib10","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/bs.ctdb.2019.10.002","article-title":"Comparative analysis of human and mouse development: From zygote to pre-gastrulation","volume":"136","author":"Mol\u00e8","year":"2020","journal-title":"Curr. Top. Dev. Biol."},{"key":"10.1016\/j.devcel.2024.03.007_bib11","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1016\/j.devcel.2021.08.012","article-title":"Establishment of the vertebrate body plan: rethinking gastrulation through stem cell models of early embryogenesis","volume":"56","author":"Steventon","year":"2021","journal-title":"Dev. Cell"},{"key":"10.1016\/j.devcel.2024.03.007_bib12","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1126\/science.aax0164","article-title":"Self-organization of stem cells into embryos: A window on early mammalian development","volume":"364","author":"Shahbazi","year":"2019","journal-title":"Science"},{"key":"10.1016\/j.devcel.2024.03.007_bib13","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1038\/s41587-021-01004-4","article-title":"Engineered models of the human embryo","volume":"39","author":"Popovic","year":"2021","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.devcel.2024.03.007_bib14","doi-asserted-by":"crossref","first-page":"3548","DOI":"10.1016\/j.cell.2023.07.028","article-title":"An ethical framework for human embryology with embryo models","volume":"186","author":"Rivron","year":"2023","journal-title":"Cell"},{"key":"10.1016\/j.devcel.2024.03.007_bib15","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1038\/s41586-021-03372-y","article-title":"Modelling human blastocysts by reprogramming fibroblasts into iBlastoids","volume":"591","author":"Liu","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2024.03.007_bib16","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1038\/s41586-021-03356-y","article-title":"Blastocyst-like structures generated from human pluripotent stem cells","volume":"591","author":"Yu","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2024.03.007_bib17","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1016\/j.stem.2021.04.031","article-title":"Naive stem cell blastocyst model captures human embryo lineage segregation","volume":"28","author":"Yanagida","year":"2021","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.devcel.2024.03.007_bib18","doi-asserted-by":"crossref","first-page":"5550","DOI":"10.1038\/s41467-021-25853-4","article-title":"Reconstructing aspects of human embryogenesis with pluripotent stem cells","volume":"12","author":"Sozen","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.devcel.2024.03.007_bib19","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1038\/s41421-021-00316-8","article-title":"Generation of human blastocyst-like structures from pluripotent stem cells","volume":"7","author":"Fan","year":"2021","journal-title":"Cell Discov."},{"key":"10.1016\/j.devcel.2024.03.007_bib20","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1038\/s41586-021-04267-8","article-title":"Human blastoids model blastocyst development and implantation","volume":"601","author":"Kagawa","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2024.03.007_bib21","doi-asserted-by":"crossref","first-page":"3290","DOI":"10.1016\/j.cell.2022.07.028","article-title":"Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs","volume":"185","author":"Tarazi","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.devcel.2024.03.007_bib22","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/s41586-022-05246-3","article-title":"Embryo model completes gastrulation to neurulation and organogenesis","volume":"610","author":"Amadei","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2024.03.007_bib23","first-page":"562","article-title":"Complete human day 14 post-implantation embryo models from naive ES cells","volume":"622","author":"Oldak","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2024.03.007_bib24","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1038\/s41586-023-06354-4","article-title":"Self-patterning of human stem cells into post-implantation lineages","volume":"622","author":"Pedroza","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2024.03.007_bib25","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1038\/s41586-023-06368-y","article-title":"Pluripotent stem cell-derived model of the post-implantation human embryo","volume":"622","author":"Weatherbee","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2024.03.007_bib26","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/s41422-023-00846-8","article-title":"Dissecting peri-implantation development using cultured human embryos and embryo-like assembloids","volume":"33","author":"Ai","year":"2023","journal-title":"Cell Res."},{"key":"10.1016\/j.devcel.2024.03.007_bib27","doi-asserted-by":"crossref","first-page":"3776","DOI":"10.1016\/j.cell.2023.07.018","article-title":"Modeling post-implantation stages of human development into early organogenesis with stem-cell-derived peri-gastruloids","volume":"186","author":"Liu","year":"2023","journal-title":"Cell"},{"key":"10.1016\/j.devcel.2024.03.007_bib28","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1016\/j.stem.2023.08.005","article-title":"3D-cultured blastoids model human embryogenesis from pre-implantation to early gastrulation stages","volume":"30","author":"Karvas","year":"2023","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.devcel.2024.03.007_bib29","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1038\/d41586-021-00695-8","article-title":"Lab-grown structures mimic human embryo's earliest stage yet","volume":"591","author":"Subbaraman","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2024.03.007_bib30","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1038\/d41586-021-00581-3","article-title":"First complete model of the human embryo","volume":"591","author":"Zheng","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2024.03.007_bib31","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1038\/s41556-019-0349-7","article-title":"A 3D model of a human epiblast reveals BMP4-driven symmetry breaking","volume":"21","author":"Simunovic","year":"2019","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.devcel.2024.03.007_bib32","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1038\/nmat4829","article-title":"Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche","volume":"16","author":"Shao","year":"2017","journal-title":"Nat. Mater."},{"key":"10.1016\/j.devcel.2024.03.007_bib33","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1038\/s41467-017-00236-w","article-title":"A pluripotent stem cell-based model for post-implantation human amniotic sac development","volume":"8","author":"Shao","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.devcel.2024.03.007_bib34","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1038\/s41586-019-1535-2","article-title":"Controlled modelling of human epiblast and amnion development using stem cells","volume":"573","author":"Zheng","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2024.03.007_bib35","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1038\/nmeth.3016","article-title":"A method to recapitulate early embryonic spatial patterning in human embryonic stem cells","volume":"11","author":"Warmflash","year":"2014","journal-title":"Nat. Methods"},{"key":"10.1016\/j.devcel.2024.03.007_bib36","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1038\/s41586-020-2383-9","article-title":"An in\u00a0vitro model of early anteroposterior organization during human development","volume":"582","author":"Moris","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2024.03.007_bib37","doi-asserted-by":"crossref","first-page":"R207","DOI":"10.1016\/j.cub.2017.02.006","article-title":"Basement membranes","volume":"27","author":"Jayadev","year":"2017","journal-title":"Curr. Biol."},{"key":"10.1016\/j.devcel.2024.03.007_bib38","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.239889","article-title":"The basement membrane as a structured surface\u00a0\u2013 role in vascular health and disease","volume":"133","author":"Leclech","year":"2020","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.devcel.2024.03.007_bib39","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/bs.ctdb.2018.02.005","article-title":"Basement membranes in development and disease","volume":"130","author":"Sekiguchi","year":"2018","journal-title":"Curr. Top. Dev. Biol."},{"key":"10.1016\/j.devcel.2024.03.007_bib40","doi-asserted-by":"crossref","DOI":"10.1242\/dev.175596","article-title":"The extracellular matrix in development","volume":"147","author":"Walma","year":"2020","journal-title":"Development"},{"key":"10.1016\/j.devcel.2024.03.007_bib41","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abn2265","article-title":"A basement membrane discovery pipeline uncovers network complexity, regulators, and human disease associations","volume":"8","author":"Jayadev","year":"2022","journal-title":"Sci. Adv."},{"key":"10.1016\/j.devcel.2024.03.007_bib42","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1007\/s00018-016-2381-0","article-title":"Laminin: loss-of-function studies","volume":"74","author":"Yao","year":"2017","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.devcel.2024.03.007_bib43","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/dvdy.23711","article-title":"Mouse primitive streak forms in\u00a0situ by initiation of epithelial to mesenchymal transition without migration of a cell population","volume":"241","author":"Williams","year":"2012","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.devcel.2024.03.007_bib44","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1016\/j.cell.2014.01.023","article-title":"Self-organizing properties of mouse pluripotent cells initiate morphogenesis upon implantation","volume":"156","author":"Bedzhov","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.devcel.2024.03.007_bib45","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1038\/s41586-020-2264-2","article-title":"Basement membrane remodelling regulates mouse embryogenesis","volume":"582","author":"Kyprianou","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2024.03.007_bib46","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/0002-9378(58)90185-6","article-title":"A thirteen-day human ovum studied histochemically","volume":"76","author":"Hertig","year":"1958","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.devcel.2024.03.007_bib47","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.ydbio.2012.12.008","article-title":"Analysis of human embryos from zygote to blastocyst reveals distinct gene expression patterns relative to the mouse","volume":"375","author":"Niakan","year":"2013","journal-title":"Dev. Biol."},{"key":"10.1016\/j.devcel.2024.03.007_bib48","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/s41580-019-0134-2","article-title":"Integrins as biomechanical sensors of the microenvironment","volume":"20","author":"Kechagia","year":"2019","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.devcel.2024.03.007_bib49","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1038\/s41556-018-0223-z","article-title":"Integrin trafficking in cells and tissues","volume":"21","author":"Moreno-Layseca","year":"2019","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.devcel.2024.03.007_bib50","doi-asserted-by":"crossref","first-page":"1886","DOI":"10.1002\/pmic.200900758","article-title":"Matrigel: a complex protein mixture required for optimal growth of cell culture","volume":"10","author":"Hughes","year":"2010","journal-title":"Proteomics"},{"key":"10.1016\/j.devcel.2024.03.007_bib51","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.1700764","article-title":"A versatile 3D tissue matrix scaffold system for tumor modeling and drug screening","volume":"3","author":"Rijal","year":"2017","journal-title":"Sci. Adv."},{"key":"10.1016\/j.devcel.2024.03.007_bib52","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1038\/ncb0901-831","article-title":"Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly","volume":"3","author":"O\u2019Brien","year":"2001","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.devcel.2024.03.007_bib53","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1091\/mbc.e04-05-0435","article-title":"\u03b21-Integrin orients epithelial polarity via Rac1 and laminin","volume":"16","author":"Yu","year":"2005","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.devcel.2024.03.007_bib54","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1021\/acschembio.8b00038","article-title":"Activation of Rho family GTPases by small molecules","volume":"13","author":"Palsuledesai","year":"2018","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.devcel.2024.03.007_bib55","doi-asserted-by":"crossref","first-page":"5971","DOI":"10.1038\/onc.2015.45","article-title":"An EGFR\/PI3K\/AKT axis promotes accumulation of the Rac1-GEF Tiam1 that is critical in EGFR-driven tumorigenesis","volume":"34","author":"Zhu","year":"2015","journal-title":"Oncogene"},{"key":"10.1016\/j.devcel.2024.03.007_bib56","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1002\/stem.1365","article-title":"Oct4 interaction with Hmgb2 regulates Akt signaling and pluripotency","volume":"31","author":"Campbell","year":"2013","journal-title":"Stem Cells"},{"key":"10.1016\/j.devcel.2024.03.007_bib57","doi-asserted-by":"crossref","first-page":"10581","DOI":"10.1073\/pnas.1202810109","article-title":"Small molecule-induced cytosolic activation of protein kinase Akt rescues ischemia-elicited neuronal death","volume":"109","author":"Jo","year":"2012","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.devcel.2024.03.007_bib58","doi-asserted-by":"crossref","first-page":"2967","DOI":"10.1073\/pnas.1811923116","article-title":"ERK2 regulates epithelial-to-mesenchymal plasticity through DOCK10-dependent Rac1\/FoxO1 activation","volume":"116","author":"Shin","year":"2019","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"10.1016\/j.devcel.2024.03.007_bib59","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1016\/j.biocel.2003.12.010","article-title":"Papilin, a novel component of basement membranes, in relation to ADAMTS metalloproteases and ECM development","volume":"36","author":"Fessler","year":"2004","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.devcel.2024.03.007_bib60","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1242\/dev.028472","article-title":"C.\u00a0elegans mig-6 encodes papilin isoforms that affect distinct aspects of DTC migration, and interacts genetically with mig-17 and collagen IV","volume":"136","author":"Kawano","year":"2009","journal-title":"Development"},{"key":"10.1016\/j.devcel.2024.03.007_bib61","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.devcel.2020.05.022","article-title":"Comprehensive Endogenous Tagging of Basement Membrane Components Reveals Dynamic Movement within the Matrix Scaffolding","volume":"54","author":"Keeley","year":"2020","journal-title":"Dev. Cell"},{"key":"10.1016\/j.devcel.2024.03.007_bib62","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1093\/humupd\/8.4.333","article-title":"Conception to ongoing pregnancy: The black box of early pregnancy loss","volume":"8","author":"Macklon","year":"2002","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.devcel.2024.03.007_bib63","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1056\/NEJMra000763","article-title":"Implantation and the survival of early pregnancy","volume":"345","author":"Norwitz","year":"2001","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.devcel.2024.03.007_bib64","doi-asserted-by":"crossref","first-page":"dev179564","DOI":"10.1242\/dev.179564","article-title":"Mapping cell migrations and fates in a gastruloid model to the human primitive streak","volume":"146","author":"Martyn","year":"2019","journal-title":"Development"},{"key":"10.1016\/j.devcel.2024.03.007_bib65","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.bbrc.2008.07.111","article-title":"Recombinant human laminin isoforms can support the undifferentiated growth of human embryonic stem cells","volume":"375","author":"Miyazaki","year":"2008","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.devcel.2024.03.007_bib66","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0138346","article-title":"Changes in laminin expression pattern during early differentiation of human embryonic stem cells","volume":"10","author":"Pook","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.devcel.2024.03.007_bib67","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1242\/jcs.069773","article-title":"COPII-mediated vesicle formation at a glance","volume":"124","author":"Jensen","year":"2011","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.devcel.2024.03.007_bib68","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.biocel.2013.11.005","article-title":"Trafficking mechanisms of extracellular matrix macromolecules: insights from vertebrate development and human diseases","volume":"47","author":"Unlu","year":"2014","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.devcel.2024.03.007_bib69","doi-asserted-by":"crossref","DOI":"10.1242\/dmm.043448","article-title":"Membrane trafficking in health and disease","volume":"13","author":"Yarwood","year":"2020","journal-title":"Dis. Model. Mech."},{"key":"10.1016\/j.devcel.2024.03.007_bib70","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s12861-015-0054-0","article-title":"Development of the follicular basement membrane during human gametogenesis and early folliculogenesis","volume":"15","author":"Heeren","year":"2015","journal-title":"BMC Dev. Biol."},{"key":"10.1016\/j.devcel.2024.03.007_bib71","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.reth.2019.04.010","article-title":"Molecular profiling of the basement membrane of pluripotent epiblast cells\u00a0in post-implantation stage mouse embryos","volume":"12","author":"Futaki","year":"2019","journal-title":"Regen. Ther."},{"key":"10.1016\/j.devcel.2024.03.007_bib72","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1038\/ncb2965","article-title":"The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification","volume":"16","author":"Boroviak","year":"2014","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.devcel.2024.03.007_bib73","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.ceb.2010.10.015","article-title":"Nuclear mechanics during cell migration","volume":"23","author":"Friedl","year":"2011","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.devcel.2024.03.007_bib74","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.ceb.2018.01.014","article-title":"Dealing with\u00a0the nucleus during cell migration","volume":"50","author":"Calero-Cuenca","year":"2018","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.devcel.2024.03.007_bib75","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/2045-9769-3-7","article-title":"Role of Oct4 in the early embryo development","volume":"3","author":"Wu","year":"2014","journal-title":"Cell Regen."},{"key":"10.1016\/j.devcel.2024.03.007_bib76","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.stem.2019.06.010","article-title":"Defining human pluripotency","volume":"25","author":"Yilmaz","year":"2019","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.devcel.2024.03.007_bib77","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1038\/nature24033","article-title":"Genome editing reveals a role for OCT4 in human embryogenesis","volume":"550","author":"Fogarty","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2024.03.007_bib78","doi-asserted-by":"crossref","first-page":"1980","DOI":"10.1016\/j.bbrc.2018.07.145","article-title":"OCT4 directly regulates stemness and extracellular matrix-related genes in human germ cell tumours","volume":"503","author":"Song","year":"2018","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.devcel.2024.03.007_bib79","doi-asserted-by":"crossref","first-page":"3569","DOI":"10.1128\/MCB.01366-09","article-title":"Rac1 is essential for basement membrane-dependent epiblast survival","volume":"30","author":"He","year":"2010","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.devcel.2024.03.007_bib80","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.molcel.2012.08.030","article-title":"Reciprocal regulation of Akt and Oct4 promotes the self-renewal and survival of embryonal carcinoma cells","volume":"48","author":"Lin","year":"2012","journal-title":"Mol. Cell"},{"key":"10.1016\/j.devcel.2024.03.007_bib81","doi-asserted-by":"crossref","first-page":"14416","DOI":"10.1073\/pnas.251547198","article-title":"Akt\/PKB regulates laminin and collagen IV isotypes of the basement membrane","volume":"98","author":"Li","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.devcel.2024.03.007_bib82","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/nmeth.2019","article-title":"Fiji: an open-source platform for biological-image analysis","volume":"9","author":"Schindelin","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1016\/j.devcel.2024.03.007_bib83","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-017-00661-x","article-title":"Human stem cells alter the invasive properties of somatic cells via paracrine activation of mTORC1","volume":"8","author":"Rosner","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.devcel.2024.03.007_bib84","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/j.stemcr.2015.10.015","article-title":"Lumen Formation Is an Intrinsic Property of Isolated Human Pluripotent Stem Cells","volume":"5","author":"Taniguchi","year":"2015","journal-title":"Stem Cell Rep."},{"key":"10.1016\/j.devcel.2024.03.007_bib85","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1038\/nprot.2010.74","article-title":"Efficient siRNA-mediated prolonged gene silencing in human amniotic fluid stem cells","volume":"5","author":"Rosner","year":"2010","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.devcel.2024.03.007_bib86","article-title":"An antibody-based approach for the in\u00a0situ evaluation of mouse contribution in human stem cell-derived xenografts","author":"Rosner","year":"2018","journal-title":"Protocolexchange"},{"key":"10.1016\/j.devcel.2024.03.007_bib87","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1038\/nmeth.2076","article-title":"ViBE-Z: a framework for 3D virtual colocalization analysis in zebrafish larval brains","volume":"9","author":"Ronneberger","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1016\/j.devcel.2024.03.007_bib88","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1038\/s41596-019-0160-8","article-title":"High-resolution 3D imaging of fixed and cleared organoids","volume":"14","author":"Dekkers","year":"2019","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.devcel.2024.03.007_bib89","first-page":"2878","article-title":"Duodenal macrophages control dietary iron absorption via local degradation of transferrin","volume":"141","author":"Sukhbaatar","year":"2023","journal-title":"Blood"}],"container-title":["Developmental Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1534580724001758?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1534580724001758?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T20:17:44Z","timestamp":1717532264000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1534580724001758"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":89,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["S1534580724001758"],"URL":"https:\/\/doi.org\/10.1016\/j.devcel.2024.03.007","relation":{},"ISSN":["1534-5807"],"issn-type":[{"value":"1534-5807","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Oct4 controls basement membrane development during human embryogenesis","name":"articletitle","label":"Article Title"},{"value":"Developmental Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.devcel.2024.03.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}