{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T20:09:18Z","timestamp":1791144558473,"version":"4.1.0"},"reference-count":66,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":367,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100018542","name":"Natural Science Foundation of Sichuan Province","doi-asserted-by":"publisher","award":["2024040701010031"],"award-info":[{"award-number":["2024040701010031"]}],"id":[{"id":"10.13039\/501100018542","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32270951"],"award-info":[{"award-number":["32270951"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82425027"],"award-info":[{"award-number":["82425027"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31930040"],"award-info":[{"award-number":["31930040"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32470960"],"award-info":[{"award-number":["32470960"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32070900"],"award-info":[{"award-number":["32070900"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["823B1006"],"award-info":[{"award-number":["823B1006"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012165","name":"Key Technologies Research and Development Program","doi-asserted-by":"publisher","award":["2023YFC2306100"],"award-info":[{"award-number":["2023YFC2306100"]}],"id":[{"id":"10.13039\/501100012165","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012165","name":"Key Technologies Research and Development Program","doi-asserted-by":"publisher","award":["2022YFC3401500"],"award-info":[{"award-number":["2022YFC3401500"]}],"id":[{"id":"10.13039\/501100012165","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2042022dx0003"],"award-info":[{"award-number":["2042022dx0003"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2042024YXB001"],"award-info":[{"award-number":["2042024YXB001"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental Cell"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.devcel.2024.10.010","type":"journal-article","created":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T10:34:42Z","timestamp":1730975682000},"page":"379-395.e8","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"title":["A subset of neutrophils activates anti-tumor immunity and inhibits non-small-cell lung cancer progression"],"prefix":"10.1016","volume":"60","author":[{"given":"Zhen","family":"Tang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu-Chang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han-Yue","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Yao","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Shuai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Conghua","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dandan","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.devcel.2024.10.010_bib1","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1016\/j.cell.2023.03.006","article-title":"Immune checkpoint therapy-current perspectives and future directions","volume":"186","author":"Sharma","year":"2023","journal-title":"Cell"},{"key":"10.1016\/j.devcel.2024.10.010_bib2","doi-asserted-by":"crossref","first-page":"5309","DOI":"10.1016\/j.cell.2021.09.020","article-title":"Hallmarks of response, resistance, and toxicity to immune checkpoint blockade","volume":"184","author":"Morad","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.devcel.2024.10.010_bib3","doi-asserted-by":"crossref","first-page":"784","DOI":"10.3389\/fimmu.2020.00784","article-title":"The Tumor Microenvironment in the Response to Immune Checkpoint Blockade Therapies","volume":"11","author":"Petitprez","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.devcel.2024.10.010_bib4","article-title":"Therapeutic Implications of Tumor Microenvironment in Lung Cancer: Focus on Immune Checkpoint Blockade","volume":"12","author":"Genova","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.devcel.2024.10.010_bib5","first-page":"7","article-title":"Cancer statistics, 2022","volume":"72","author":"Siegel","year":"2022","journal-title":"CA Cancer J. Clin."},{"key":"10.1016\/j.devcel.2024.10.010_bib6","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/cac2.12393","article-title":"Cancer situation in China: what does the China cancer map indicate from the first national death survey to the latest cancer registration?","volume":"43","author":"Feng","year":"2023","journal-title":"Cancer Commun. (Lond)"},{"key":"10.1016\/j.devcel.2024.10.010_bib7","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1200\/JCO.21.01845","article-title":"Managing Resistance to Immune Checkpoint Inhibitors in Lung Cancer: Treatment and Novel Strategies","volume":"40","author":"Passaro","year":"2022","journal-title":"J.\u00a0Clin. Oncol."},{"key":"10.1016\/j.devcel.2024.10.010_bib8","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/s41423-020-00577-5","article-title":"The cutting-edge progress of immune-checkpoint blockade in lung cancer","volume":"18","author":"Zhou","year":"2021","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.devcel.2024.10.010_bib9","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/s41577-019-0218-4","article-title":"Tumour-intrinsic resistance to immune checkpoint blockade","volume":"20","author":"Kalbasi","year":"2020","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.devcel.2024.10.010_bib10","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1056\/NEJMoa1507643","article-title":"Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung Cancer","volume":"373","author":"Borghaei","year":"2015","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.devcel.2024.10.010_bib11","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1056\/NEJMoa1504627","article-title":"Nivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung Cancer","volume":"373","author":"Brahmer","year":"2015","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.devcel.2024.10.010_bib12","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s12943-021-01489-2","article-title":"Combination strategies with PD-1\/PD-L1 blockade: current advances and future directions","volume":"21","author":"Yi","year":"2022","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.devcel.2024.10.010_bib13","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1038\/s41586-023-06069-6","article-title":"The complementarity of DDR, nucleic acids and anti-tumour immunity","volume":"619","author":"Kornepati","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2024.10.010_bib14","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1200\/JCO.21.01497","article-title":"First-Line Immunotherapy for Non-Small-Cell Lung Cancer","volume":"40","author":"Reck","year":"2022","journal-title":"J.\u00a0Clin. Oncol."},{"key":"10.1016\/j.devcel.2024.10.010_bib15","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1016\/j.immuni.2019.03.009","article-title":"Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species","volume":"50","author":"Zilionis","year":"2019","journal-title":"Immunity"},{"key":"10.1016\/j.devcel.2024.10.010_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.smim.2021.101538","article-title":"Versatile neutrophil functions in cancer","volume":"57","author":"Siwicki","year":"2021","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.devcel.2024.10.010_bib17","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1038\/s41571-019-0222-4","article-title":"Tumour-associated neutrophils in patients with cancer","volume":"16","author":"Shaul","year":"2019","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"10.1016\/j.devcel.2024.10.010_bib18","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1016\/j.ccell.2022.10.008","article-title":"High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in non-small cell lung cancer","volume":"40","author":"Salcher","year":"2022","journal-title":"Cancer Cell"},{"key":"10.1016\/j.devcel.2024.10.010_bib19","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1038\/s41577-021-00571-6","article-title":"Neutrophils in cancer: heterogeneous and multifaceted","volume":"22","author":"Hedrick","year":"2022","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.devcel.2024.10.010_bib20","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1038\/s41577-019-0141-8","article-title":"Heterogeneity of neutrophils","volume":"19","author":"Ng","year":"2019","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.devcel.2024.10.010_bib21","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1186\/s12943-023-01843-6","article-title":"The evolution and heterogeneity of neutrophils in cancers: origins, subsets, functions, orchestrations and clinical applications","volume":"22","author":"Liu","year":"2023","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.devcel.2024.10.010_bib22","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1038\/s41568-020-0281-y","article-title":"Neutrophil diversity and plasticity in tumour progression and therapy","volume":"20","author":"Jaillon","year":"2020","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.devcel.2024.10.010_bib23","doi-asserted-by":"crossref","first-page":"3163","DOI":"10.1016\/j.cell.2021.04.016","article-title":"Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis","volume":"184","author":"Cui","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.devcel.2024.10.010_bib24","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.ccell.2016.06.001","article-title":"Origin and Role of a Subset of Tumor-Associated Neutrophils with Antigen-Presenting Cell Features in Early-Stage Human Lung Cancer","volume":"30","author":"Singhal","year":"2016","journal-title":"Cancer Cell"},{"key":"10.1016\/j.devcel.2024.10.010_bib25","doi-asserted-by":"crossref","first-page":"5466","DOI":"10.1172\/JCI77053","article-title":"Tumor-associated neutrophils stimulate T\u00a0cell responses in early-stage human lung cancer","volume":"124","author":"Eruslanov","year":"2014","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.devcel.2024.10.010_bib26","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1007\/s00262-017-1976-0","article-title":"Phenotype and function of tumor-associated neutrophils and their subsets in early-stage human lung cancer","volume":"66","author":"Eruslanov","year":"2017","journal-title":"Cancer Immunol. Immunother."},{"key":"10.1016\/j.devcel.2024.10.010_bib27","doi-asserted-by":"crossref","first-page":"14.35.1","DOI":"10.1002\/0471141755.ph1435s70","article-title":"Overview of KRAS-Driven Genetically Engineered Mouse Models of Non-Small Cell Lung Cancer","volume":"70","author":"Sheridan","year":"2015","journal-title":"Curr. Protoc. Pharmacol."},{"key":"10.1016\/j.devcel.2024.10.010_bib28","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1101\/gad.1417406","article-title":"Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors","volume":"20","author":"Politi","year":"2006","journal-title":"Genes Dev."},{"key":"10.1016\/j.devcel.2024.10.010_bib29","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.ccr.2007.06.005","article-title":"Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy","volume":"12","author":"Li","year":"2007","journal-title":"Cancer Cell"},{"key":"10.1016\/j.devcel.2024.10.010_bib30","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.ccr.2006.04.022","article-title":"The impact of human EGFR kinase domain mutations on lung tumorigenesis and in\u00a0vivo sensitivity to EGFR-targeted therapies","volume":"9","author":"Ji","year":"2006","journal-title":"Cancer Cell"},{"key":"10.1016\/j.devcel.2024.10.010_bib31","doi-asserted-by":"crossref","first-page":"3243","DOI":"10.1101\/gad.943001","article-title":"Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras. Genes Dev","volume":"15","author":"Jackson","year":"2001","journal-title":"Genes Dev."},{"key":"10.1016\/j.devcel.2024.10.010_bib32","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1038\/nature10937","article-title":"A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response","volume":"483","author":"Chen","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.devcel.2024.10.010_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.108164","article-title":"Tumor-Promoting Ly-6G+ SiglecFhigh Cells Are Mature and Long-Lived Neutrophils","volume":"32","author":"Pfirschke","year":"2020","journal-title":"Cell Rep."},{"key":"10.1016\/j.devcel.2024.10.010_bib34","doi-asserted-by":"crossref","DOI":"10.1126\/science.aal5081","article-title":"Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils","volume":"358","author":"Engblom","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.devcel.2024.10.010_bib35","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1111\/imr.13154","article-title":"Human neutrophils \u2260 murine neutrophils: Does it matter?","volume":"314","author":"Nauseef","year":"2023","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.devcel.2024.10.010_bib36","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/s41423-023-00974-6","article-title":"The chemokines CXCL8 and CXCL12: molecular and functional properties, role in disease and efforts towards pharmacological intervention","volume":"20","author":"Cambier","year":"2023","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.devcel.2024.10.010_bib37","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-020-19973-6","article-title":"CCL7 recruits cDC1 to promote antitumor immunity and facilitate checkpoint immunotherapy to non-small cell lung cancer","volume":"11","author":"Zhang","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.devcel.2024.10.010_bib38","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.ccell.2023.03.004","article-title":"Neutralizing IL-8 potentiates immune checkpoint blockade efficacy for glioma","volume":"41","author":"Liu","year":"2023","journal-title":"Cancer Cell"},{"key":"10.1016\/j.devcel.2024.10.010_bib39","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s13073-023-01164-9","article-title":"Tumor microenvironment remodeling after neoadjuvant immunotherapy in non-small cell lung cancer revealed by single-cell RNA sequencing","volume":"15","author":"Hu","year":"2023","journal-title":"Genome Med."},{"key":"10.1016\/j.devcel.2024.10.010_bib40","article-title":"IL-36gamma and IL-36Ra Reciprocally Regulate NSCLC Progression by Modulating GSH Homeostasis and Oxidative Stress-Induced Cell Death","volume":"8","author":"Wang","year":"2021","journal-title":"Adv. Sci. (Weinh)"},{"key":"10.1016\/j.devcel.2024.10.010_bib41","doi-asserted-by":"crossref","first-page":"29355","DOI":"10.1016\/S0021-9258(18)43882-3","article-title":"The murine interleukin 8 type B receptor homologue and its ligands. Expression and biological characterization","volume":"269","author":"Bozic","year":"1994","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.devcel.2024.10.010_bib42","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1126\/science.8036519","article-title":"Neutrophil and B cell expansion in mice that lack the murine IL-8 receptor homolog","volume":"265","author":"Cacalano","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.devcel.2024.10.010_bib43","doi-asserted-by":"crossref","first-page":"5269","DOI":"10.4049\/jimmunol.165.9.5269","article-title":"The CXC chemokine receptor 2, CXCR2, is the putative receptor for ELR+ CXC chemokine-induced angiogenic activity","volume":"165","author":"Addison","year":"2000","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.devcel.2024.10.010_bib44","doi-asserted-by":"crossref","first-page":"11658","DOI":"10.1074\/jbc.M607705200","article-title":"Murine CXCR1 is a functional receptor for GCP-2\/CXCL6 and interleukin-8\/CXCL8","volume":"282","author":"Fan","year":"2007","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.devcel.2024.10.010_bib45","doi-asserted-by":"crossref","first-page":"7033","DOI":"10.1016\/j.bmcl.2010.09.118","article-title":"Receptor agonists of macrophage migration inhibitory factor","volume":"20","author":"Jorgensen","year":"2010","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.devcel.2024.10.010_bib46","doi-asserted-by":"crossref","first-page":"3823","DOI":"10.21037\/tlcr-21-572","article-title":"Tumor immune microenvironment in epidermal growth factor receptor-mutated non-small cell lung cancer before and after epidermal growth factor receptor tyrosine kinase inhibitor treatment: a narrative review","volume":"10","author":"Liu","year":"2021","journal-title":"Transl. Lung Cancer Res."},{"key":"10.1016\/j.devcel.2024.10.010_bib47","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1146\/annurev-immunol-102419-035900","article-title":"Siglecs as Immune Cell Checkpoints in Disease","volume":"38","author":"Duan","year":"2020","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.devcel.2024.10.010_bib48","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1038\/s41571-023-00794-7","article-title":"Immune-checkpoint inhibition for resectable non-small-cell lung cancer - opportunities and challenges","volume":"20","author":"Mountzios","year":"2023","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"10.1016\/j.devcel.2024.10.010_bib49","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1016\/j.cell.2024.02.005","article-title":"Neutrophil profiling illuminates anti-tumor antigen-presenting potency","volume":"187","author":"Wu","year":"2024","journal-title":"Cell"},{"key":"10.1016\/j.devcel.2024.10.010_bib50","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1158\/1078-0432.CCR-20-1319","article-title":"IL8, Neutrophils, and NETs in a Collusion against Cancer Immunity and Immunotherapy","volume":"27","author":"Teijeira","year":"2021","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.devcel.2024.10.010_bib51","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.cytogfr.2016.08.002","article-title":"The CXCL8-CXCR1\/2 pathways in cancer","volume":"31","author":"Liu","year":"2016","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.devcel.2024.10.010_bib52","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1159061","article-title":"CXCL8 and the peritoneal metastasis of ovarian and gastric cancer","volume":"14","author":"Fu","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.devcel.2024.10.010_bib53","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.ctrv.2017.08.004","article-title":"Interleukin-8 in cancer pathogenesis, treatment and follow-up","volume":"60","author":"Alfaro","year":"2017","journal-title":"Cancer Treat. Rev."},{"key":"10.1016\/j.devcel.2024.10.010_bib54","doi-asserted-by":"crossref","DOI":"10.3390\/cells11152402","article-title":"The AGEs\/RAGE Transduction Signaling Prompts IL-8\/CXCR1\/2-Mediated Interaction between Cancer-Associated Fibroblasts (CAFs) and Breast Cancer Cells","volume":"11","author":"Santolla","year":"2022","journal-title":"Cells"},{"key":"10.1016\/j.devcel.2024.10.010_bib55","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1038\/s41419-023-06230-z","article-title":"Targeting cancer-associated adipocyte-derived CXCL8 inhibits triple-negative breast cancer progression and enhances the efficacy of anti-PD-1 immunotherapy","volume":"14","author":"Huang","year":"2023","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.devcel.2024.10.010_bib56","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1172\/JCI39397","article-title":"CXCR1 blockade selectively targets human breast cancer stem cells in\u00a0vitro and in xenografts","volume":"120","author":"Ginestier","year":"2010","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.devcel.2024.10.010_bib57","doi-asserted-by":"crossref","first-page":"3573","DOI":"10.1016\/j.cell.2021.04.048","article-title":"Integrated analysis of multimodal single-cell data","volume":"184","author":"Hao","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.devcel.2024.10.010_bib58","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1038\/s41423-023-00991-5","article-title":"Combined targeting of CCL7 and Flt3L to promote the expansion and infiltration of cDC1s in tumors enhances T-cell activation and anti-PD-1 therapy effectiveness in NSCLC","volume":"20","author":"Dong","year":"2023","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.devcel.2024.10.010_bib59","doi-asserted-by":"crossref","DOI":"10.15252\/emmm.202114502","article-title":"Carfilzomib modulates tumor microenvironment to potentiate immune checkpoint therapy for cancer","volume":"14","author":"Zhou","year":"2022","journal-title":"EMBO Mol. Med."},{"key":"10.1016\/j.devcel.2024.10.010_bib60","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1093\/abbs\/gmaa032","article-title":"Dispensable role of CCL28 in Kras-mutated non-small cell lung cancer mouse models","volume":"52","author":"Lin","year":"2020","journal-title":"Acta Biochim. Biophys. Sin. (Shanghai)"},{"key":"10.1016\/j.devcel.2024.10.010_bib61","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellin.2023.100100","article-title":"The deubiquitinase OTUD4 inhibits the expression of antimicrobial peptides in Paneth cells to support intestinal inflammation and bacterial infection","volume":"2","author":"Yu","year":"2023","journal-title":"Cell Insight"},{"key":"10.1016\/j.devcel.2024.10.010_bib62","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellin.2022.100047","article-title":"USP2 promotes experimental colitis and bacterial infections by inhibiting the proliferation of myeloid cells and remodeling the extracellular matrix network","volume":"1","author":"An","year":"2022","journal-title":"Cell Insight"},{"key":"10.1016\/j.devcel.2024.10.010_bib63","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1038\/cr.2016.125","article-title":"USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING\/MITA","volume":"26","author":"Zhang","year":"2016","journal-title":"Cell Res."},{"key":"10.1016\/j.devcel.2024.10.010_bib64","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1089\/cmb.2017.0096","article-title":"cutPrimers: A New Tool for Accurate Cutting of Primers from Reads of Targeted Next Generation Sequencing","volume":"24","author":"Kechin","year":"2017","journal-title":"J.\u00a0Comput. Biol."},{"key":"10.1016\/j.devcel.2024.10.010_bib65","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","article-title":"STAR: ultrafast universal RNA-seq aligner","volume":"29","author":"Dobin","year":"2013","journal-title":"Bioinformatics"},{"key":"10.1016\/j.devcel.2024.10.010_bib66","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1093\/bioinformatics\/btt656","article-title":"featureCounts: an efficient general purpose program for assigning sequence reads to genomic features","volume":"30","author":"Liao","year":"2014","journal-title":"Bioinformatics"}],"container-title":["Developmental Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1534580724006294?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1534580724006294?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:31:53Z","timestamp":1770078713000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1534580724006294"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":66,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["S1534580724006294"],"URL":"https:\/\/doi.org\/10.1016\/j.devcel.2024.10.010","relation":{},"ISSN":["1534-5807"],"issn-type":[{"value":"1534-5807","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A subset of neutrophils activates anti-tumor immunity and inhibits non-small-cell lung cancer progression","name":"articletitle","label":"Article Title"},{"value":"Developmental Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.devcel.2024.10.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}